Objetivo: Comparar los resultados del embarazo entre mujeres con y sin COVID-19 atendidas en un hospital nacional de nivel III de Perú. Método: Estudio observacional, retrospectivo y comparativo. Participaron gestantes con RT-PCR positiva y negativa en razón 1:1, y 1:2 con gestantes del año 2019. Se recogió información materna y perinatal. Se usó la prueba exacta de Fisher con significancia de 0,05 y razones de prevalencia (RP) con intervalo de confianza del 95% (IC95%). Resultados: Participaron 51 gestantes con RT-PCR positiva, 51 gestantes con RT-PCR negativa y 102 gestantes del año 2019. Se observó asociación entre los resultados de la RT-PCR y el parto pretérmino (p < 0,05). La RP de parto pretérmino en las gestantes con RT-PCR positiva fue de 3,14 (IC95%: 1,29-7,64) veces en comparación con las gestantes de 2019 y de 4,0 (IC95%: 1,13-14,17) veces en comparación con las...

Objetivo: Describir las complicaciones en histerectomía laparoscópica realizadas desde 2009 hasta 2016 en el Instituto Nacional Materno Perinatal. Metodología: Estudio cuantitativo, descriptivo, retrospectivo. El diseño es trasversal descriptivo. La muestra: 92 pacientes. Resultados: El promedio de edad fue 47.8 ± 7.7 años. La de menor edad 36 años y la mayor, 69. El 94% (86/92) fueron multíparas y el 78% (72/92), amas de casa. El diagnóstico preoperatorio con mayor frecuencia fue leiomioma uterino con 44.6% (41/92), seguido por neoplasia intraepitelial cervical y prolapso genital con 16.3% (15/92). Los pacientes sometidos a histerectomía laparoscópica presentaron complicaciones intraoperatorias en 9% (9/92). Del total de estas complicaciones la lesión vascular se presentó en 5.4% (5/92), la lesión ureteral y vesical en 1.1% (1/92) respectivamente. El 11% (10/92) de la mues...

Objective. Determine the prevalence of endometrial histology in patients with postmenopausal uterine bleeding. Materials and methods. Observational, retrospective, cross. Study 40 cases had histopathological study of patients who had uterine bleeding whose ages were 50 or more years of age were included. Pathological findings were reviewed.

Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...

Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...

Intrauterine fetal growth restriction (IUGR), is a clinical circumstance in which the fetus does not express its genetic growth potential and as a final result there is a decrease in body weight, which is below the 10th percentile for gestational age on a selected growth curve. The global prevalence of IUGR according to different authors varies between 3,7% and 22,4%. In Peru they are reported from 4,8% to 10,1%. Obstetric factors associated with IUGR include: pre-eclampsia with OR=1,69 to OR=66,54; anemia during pregnancy OR=2,18 to OR=9,70; Previous IUGR with OR=3,26 at OR=14,49 and preterm delivery with OR=3,58 at OR=14,60.

Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.

Objective: To describe maternal characteristics and management of therapeutic abortion in women treated in a level III hospital in Peru, during 12 years of experience. Materials and Methods: Observational and retrospective study. All pregnant women who had a therapeutic interruption of pregnancy participated. The medical history of patients treated at the National Maternal Perinatal Institute of Peru, between 2009 and 2020 was reviewed. Results: 385 pregnant women were attended. The mean age was 30.4 years; 45% were nulliparous; and 51% had between 19 and 22 weeks of gestation. The causes were 7.5% due to risk of the life of the pregnant woman and 92.5% due to risk in the physical and mental health of the pregnant woman. 30% presented fetuses with multiple malformations. Uterine curettage was performed in 81%, 15.6% manual vacuum aspiration, six cases of hysterotomy. There were no cases ...

Objective: To evaluate the obstetric outcome of pregnant women with advanced maternal age (EMA) treated at the NationalMaternal Perinatal Institute. Materials and methods: Observational, descriptive and retrospective study of 321 maternaloutgoings occurred during the period from January 1 to June 30, 2016.

Objective. To identify perinatal outcomes in pregnant women with advanced maternal age (EMA) treated at the NationalMaternal Perinatal Institute. Materials and methods. Observational, descriptive and retrospective study of 321 maternaloutgoings occurred during the period from January 1 to June 30, 2016.

The genitourinary syndrome of menopause clinically is evident 4 to 5 years after menopause, and objective changes arepresent in 25-50% of all postmenopausal women. The most frequent symptoms are vaginal dryness ( 75%), dyspareunia(38%), and vaginal itching, vaginal discharge and pain (15%); and the diagnosis is based on clinical criteria. The principlestherapeutic are based on the restoration of urogenital physiology and relief of symptoms; including non-hormonal / lubricanttherapeutic options, systemic hormonal therapy, local estrogen therapy and other alternatives. The genitourinary syndromeof menopause is one of the most important determinants of sexual function and urogenital health, with a significant impact onthe quality of life related to female health.

Endocervical polyps are the most common benign pathologies of the cervix, whose etiology is still unknown. They appear in 2 to 5% of women. In general they originate in the endocervical canal and less frequently from the ectocervix. The case of a 51-year-old woman whose last menstruation date was 2 years ago is presented and goes to a climacteric office for routine, asymptomatic control and a 1x0,5 cm color polypoid tumor is visualized in the gynecological examination. Pink with shortened sessile pedicle, to whom polypectomy is performed and whose histological study reveals endocervical polyp without signs of malignancy.

Objective: To describe the epidemiological characteristics, contraception and psychological well-being in a series of women two years after therapeutic abortion. Materials and methods: Observational, descriptive study of a series of cases. The women whose therapeutic abortion procedure was performed at the National Maternal Perinatal Institute of Peru in 2018 participated and who at the time of the interview had passed two years, with prior informed consent. Sociodemographic data, obstetric profile, family planning method before therapeutic abortion and current were collected. The BIEPS Scale was applied to measure the psychological well-being of the participants two years after therapeutic abortion. Descriptive analysis was carried out and the identity of the participants was safeguarded. Results: 12 women were studied two years after presenting therapeutic abortion. At the ti...

The evaluation of quality of life should focus mainly on the patient’s perception of her state of health, being an activeparticipant in this process. Instruments for measuring health-related quality of life (HRQL) can be classified into genericinstruments that measure multiple areas or domains and that are applicable to all individuals, regardless of the pathologythat affects them; And specific instruments, which are those that measure the functioning of the patient in one or severalareas and are characterized by paying particular attention to those symptoms or problems specific to a particular diseaseand those areas considered to be most affected, being only applicable to patients Specific. In daily clinical practice it is usefulto evaluate: improvement of clinical diagnosis, individualization and prioritization of treatments, improving the doctor-patientrelationship, and monitoring c...

Fetal growth restriction (RCF) is a clinical circumstance in which the fetus does not express its genetic potential for growth and as a final result a decrease in body weight occurs, which is below the 10th percentile for gestational age, in a selected growth curve. Among the etiological factors include: maternal, fetal and placental causes. It is classified as Precocious and late. The appropriate time for delivery is determined by gestational age and fetal condition.

Objective: To describe the prevalence and characteristics of seropositive pregnant women for SARS-CoV-2. Material and methods: Quantitative, cross-sectional and descriptive study. Performed in pregnant women screened for SARS-CoV-2 who met selection criteria at hospital admission. Variables of maternal characteristics, pregnancy complications and newborn condition were collected from the respective medical history. Data analysis was performed using descriptive statistics and 95% confidence intervals. Results: 1477 pregnant women admitted to hospitalization were screened, identifying a seroprevalence of anti-SARS-CoV-2 antibodies in 5.28% (95% CI: 4.22% -6.57%). Among the cases of positive seroprevalence, IgM 11.5% (95% CI: 5.7% -21.3%), IgM / IgG 64.1% (95% CI: 5.7% -21.3%), IgG 19% (95% CI: 15.7% and 35.6) were observed %), 91% of seropositive pregnant women were asymptomatic, 40% of se...

Introduction: COVID-19 disease spreads rapidly. Seroprevalence in pregnant women entering for hospitalization and clinical characteristics in this type of population in Peru is not known. Objective: To determine the prevalence and clinical-epidemiological characteristics of pregnant women with anti-SARS-CoV-2 antibodies at a level III hospital in Peru. Methods: Observational and cross-sectional study performed at the National Maternal Perinatal Institute of Peru. Pregnant women admitted for hospitalization were screened for COVID-19 infection. Results of anti-SARSCoV-2 serological tests and information on maternal and perinatal characteristics were obtained. Data analysis was performed using descriptive statistics and 95% confidence intervals. Results: In 2 419 pregnant women screened we identified a prevalence of 7.0% of anti-SARS-CoV-2 antibodies (95% IC: 6.1% to 8.1%), including IgM i...

Introducción. La enfermedad de COVID-19 se propaga rápidamente. Se desconoce la seroprevalencia en mujeres embarazadas que ingresan a hospitalización y sus características propias en este tipo de población en Perú. Objetivo. Determinar la prevalencia y características clínico-epidemiológicas de gestantes con anticuerpos anti-SARS-CoV-2 en un hospital nivel III de Perú. Métodos. Estudio observacional de tipo transversal, realizado en el Instituto Nacional Materno Perinatal de Perú, entre el 15 de abril y 15 de mayo de 2020. Participaron todas las gestantes que ingresaron a hospitalización y fueron tamizadas para la infección por SARS-CoV-2 mediante pruebas serológicas, cuyos resultados fueron analizados conjuntamente con sus características clínicas y epidemiológicas, utilizando estadígrafos descriptivos e intervalos de confianza al 95%, y mediante la prueba de independ...

Objetivo: Identificar los factores de riesgo obstétricos y perinatales asociados a recien nacidos con malformaciones congénitas (MC) en gestantes atendidas en el Instituto Nacional Materno Perinatal durante el periodo 2018. Material y Métodos: Estudio observacional, retrospectivo, corte transversal en mujeres hospitalizadas de enero a diciembre 2018 que cumplieron con criterios de inclusión. Las variables de estudio fueron: edad materna, edad gestacional, tipo de parto, peso al nacer, puntuación Apgar al nacer, tipo de MC y supervivencia. Se utilizó análisis estadístico para cálculo de prevalencias y proporciones. Se aplicó la prueba de Mann-Whitney y Chi-cuadrado. Para estimar las curvas de sobrevida se usó el Método de Kaplan Meier. Resultados: Se enrolaron 340 casos que representan el  1,9% de prevalencia de MC. La tasa de mortalidad neonatal específica de MC fue 8,1...

Objetivos: Evaluar las diferencias en el manejo médico del aborto terapéutico usando Mifepristone más Misoprostol comparado con el uso de Misoprostol solo. Materiales y métodos: Se realizó un estudio observacional, de cohorte retrospectiva y multicéntrica (Instituto Nacional Materno Perinatal [INMP], Hospital Regional de Pucallpa, Hospital Santa Rosa de Piura y Hospital Regional de Loreto), en gestantes con indicación de aborto terapéutico, según lo establecido en la RM N° 486-2014-MINSA. Las pacientes enroladas en el INMP, al ingreso recibieron 200 mg de Mifepristona y a las 24 horas Misoprostol 800 µg colocado en fondo de saco vaginal posterior al cérvix, seguido de 400 µg vía sublingual, cada 3 horas hasta la expulsión del feto y placenta, siendo el tope 5 dosis por día; las pacientes de los tres hospitales restantes se les administro solo Misoprostol bajo el mismo esq...