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1
tesis doctoral
La morbilidad materna extrema constituye una condición grave que compromete la vida y el bienestar de las mujeres gestantes; en ese contexto, el estudio tuvo como objetivo determinar las características epidemiológicas y clínicas de los casos registrados en el Instituto Nacional Materno Perinatal durante el período 2017–2022. Se desarrolló una investigación con enfoque cuantitativo, diseño observacional, descriptivo y retrospectivo, que incluyó a la totalidad de gestantes notificadas como casos de morbilidad materna extrema según los criterios de la Organización Mundial de la Salud, mediante un muestreo censal no probabilístico. El análisis se realizó mediante estadística descriptiva, utilizando medidas de tendencia central y dispersión para variables cuantitativas, así como frecuencias absolutas y relativas para variables cualitativas. Los resultados evidenciaron una ...
2
artículo
Objectives. To determine the relationship between obesity at the beginning, in the second and third trimester of pregnancy and macrosomic newborns treated at the National Maternal Perinatal Institute during the period from 2003 to 2005. Materials and methods. An analytical, prospective study in which it was followed two cohorts of pregnant women, the first one with 210 pregnant with adequate prepregnancy weight or overweight; and the second one with 211 pregnant with prepregnancy maternal obesity. We proceeded to descriptive analysis, through percentages, means and standard deviations. For the determination of hypothesis tests proceeded to significant inferential statistics with an alpha level of statistical significance of less than 0.05. To determine the influence, it proceeded to use the Relative Risk (RR) with confidence intervals at 95%.
3
artículo
Interstitial ectopic pregnancy, misnamed cornual, is a rare pathology, but it implies a high morbidity and mortality if it is notdiagnosed and treated on time. We present the case of a one-year-old patient who attended the emergency room due topain, vaginal bleeding, and a 9-week period of amenorrhea. During the ultrasonographic evaluation, a gestational sac withan active embryo was evidenced at the level of the right uterine horn, for which the diagnosis of cornual ectopic pregnancywas considered and proceeding to perform an abdominal hysterectomy. The best knowledge of the natural history of thedisease, as well as an early and timely diagnosis, is the key to the conservative management of this disease.
4
artículo
Objective. To describe the psychological, social and gynecological characteristics of patients with gestational lossseen at the Instituto Nacional Materno Perinatal (2022). Materials and Methods. This research corresponds to aretrospective descriptive observational study, in which 176 clinical histories of patients with gestational losses duringthe year 2022 attended by the psychology service who met the inclusion and exclusion criteria were collected. Ananalysis of frequencies and percentages of the different variables was performed in order to meet the research objectives. Results. The average age of the patients was 30 years (min: 18 years and max: 46 years), with a mean of 2.64gestations in the sample, a minimum of 0 and a maximum of 4 gestational losses. Fetal death (65.34%) was the mostfrequent diagnosis of fetal death. All the patients presented a psychological disorder, with Brie...
5
artículo
Objectives. To determine the relationship between obesity at the beginning, in the second and third trimester of pregnancy and macrosomic newborns treated at the National Maternal Perinatal Institute during the period from 2003 to 2005. Materials and methods. An analytical, prospective study in which it was followed two cohorts of pregnant women, the first one with 210 pregnant with adequate prepregnancy weight or overweight; and the second one with 211 pregnant with prepregnancy maternal obesity. We proceeded to descriptive analysis, through percentages, means and standard deviations. For the determination of hypothesis tests proceeded to significant inferential statistics with an alpha level of statistical significance of less than 0.05. To determine the influence, it proceeded to use the Relative Risk (RR) with confidence intervals at 95%.
6
artículo
Objetivo. Caracterizar a las gestantes con edad materna avanzada y, de manera exploratoria, evaluar los factores asociados a la presentación de complicaciones en esta población, en un instituto materno peruano en el año 2022. Materiales y métodos. Se realizó una investigación de tipo observacional, descriptivo, de corte transversal y retrospectivo en el Instituto Nacional Materno Perinatal durante el año 2022, de las cuales se revisaron 191 historias clínicas que cumplieron con los criterios de inclusión y exclusión. Posteriormente se realizaron los análisis por medio del programa IBM SPSS versión 25.0. Se realizó un análisis estadístico descriptivo y bivariado mediante la prueba de Chi cuadrado. También se calculó las razones de prevalencia crudas con sus intervalos de confianza del 95%, usando la regresión de Poisson con varianzas robustas. Resultados. Se encontró qu...
7
artículo
Objectives: To determine the relationship between the average pulsatility index of the uterine arteries taken by ultrasound inpregnant women between 11 and 14 and 20 to 26 weeks of gestation with neonatal macrosomia. Materials and methods:Prospective, longitudinal, analytical study. A total of 3,279 pregnant women attended at the National Maternal Perinatal Institutebetween 2011 and 2014, of whom 952 were patients between 11 and 14 weeks and 2327 between 20 and 26 weeks, two groupswere formed: 11 to 14 and 20 to 26 weeks; The weights considered for the comparison were: 3,600, 3,800, 4,000, 4,200 and 4,400grams, a correlation was performed by the Pearson method, statistical significance was performed by means of Chi square test forboth groups, to calculate the probability Of occurrence of events was calculated odss ratio and to evaluate the precision were usedconfidence intervals, subsequ...
8
artículo
Objectives: To determine the relationship between the average pulsatility index of the uterine arteries taken by ultrasound inpregnant women between 11 and 14 and 20 to 26 weeks of gestation with neonatal macrosomia. Materials and methods:Prospective, longitudinal, analytical study. A total of 3,279 pregnant women attended at the National Maternal Perinatal Institutebetween 2011 and 2014, of whom 952 were patients between 11 and 14 weeks and 2327 between 20 and 26 weeks, two groupswere formed: 11 to 14 and 20 to 26 weeks; The weights considered for the comparison were: 3,600, 3,800, 4,000, 4,200 and 4,400grams, a correlation was performed by the Pearson method, statistical significance was performed by means of Chi square test forboth groups, to calculate the probability Of occurrence of events was calculated odss ratio and to evaluate the precision were usedconfidence intervals, subsequ...
9
artículo
Objetivo: Determinar la prevalencia de cesárea previa como indicación de parto por cesárea en un hospital peruano en el periodo de enero a diciembre del año 2022. Materiales y Métodos: Se realizó un estudio descriptivo a partir de la información de las historias clínicas de las gestantes con indicación de parto por cesárea atendidas en un hospital. De una población de 6100 gestantes atendidas en el 2022 se obtuvo un total de 236 historias clínicas de pacientes que se les realizó cesárea con antecedente de cesárea. Se extrajo información sociodemográfica y clínica. Resultados: Se encontró que la prevalencia de cesárea previa como indicación de parto por cesárea fue de un 21.6%. La edad media de las pacientes atendidas fue de 32.5 años, el grado de instrucción más prevalente fue de secundaria completa con un 57.6%, el 75.4% de pacientes fueron convivientes, fina...
10
artículo
Objective. Misoprostol is an analogous of Prostaglandin E1, used for induction of labor when Bishop score is lower than 6. The goal of the study is to describe la eficacy of 25 μg vaginal misoprostol to induction of labor in term gestantions with live fetus. Also describe others outcomes like way of delivery, characteristics of newborn, adverse maternal and perinatal outcomes. Materials and methods. Descriptive and retrospective study. Population: pregnant women hospitalized in Obstetrics C Unit at Instituto Nacional Materno Perinatal for induction of labor with vaginal misoprostol. Period: may 2009 to march 2010. Data in SPSS version 13 to statistics analysis. Results. 25 μg vaginal misoprostol each 6 hours was administrated to 39 pregnants. Mean age was 27 years. Gestacional age 40 weeks (between 37 to 42). 51% was nulliparous, 92% pregnants had Bishop score lower than 5. It is achie...
11
artículo
Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...
12
artículo
Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...
13
artículo
Objective. Misoprostol is an analogous of Prostaglandin E1, used for induction of labor when Bishop score is lower than 6. The goal of the study is to describe la eficacy of 25 μg vaginal misoprostol to induction of labor in term gestantions with live fetus. Also describe others outcomes like way of delivery, characteristics of newborn, adverse maternal and perinatal outcomes. Materials and methods. Descriptive and retrospective study. Population: pregnant women hospitalized in Obstetrics C Unit at Instituto Nacional Materno Perinatal for induction of labor with vaginal misoprostol. Period: may 2009 to march 2010. Data in SPSS version 13 to statistics analysis. Results. 25 μg vaginal misoprostol each 6 hours was administrated to 39 pregnants. Mean age was 27 years. Gestacional age 40 weeks (between 37 to 42). 51% was nulliparous, 92% pregnants had Bishop score lower than 5. It is achie...
14
artículo
Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...
15
artículo
Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...
16
artículo
Intrauterine fetal growth restriction (IUGR), is a clinical circumstance in which the fetus does not express its genetic growth potential and as a final result there is a decrease in body weight, which is below the 10th percentile for gestational age on a selected growth curve. The global prevalence of IUGR according to different authors varies between 3,7% and 22,4%. In Peru they are reported from 4,8% to 10,1%. Obstetric factors associated with IUGR include: pre-eclampsia with OR=1,69 to OR=66,54; anemia during pregnancy OR=2,18 to OR=9,70; Previous IUGR with OR=3,26 at OR=14,49 and preterm delivery with OR=3,58 at OR=14,60.
17
artículo
Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.
18
artículo
Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.
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artículo
Postmenopausal women in the presence of abnormal uterine bleeding spontaneously and unexpectedly requires rigorous evaluation to determine the source of the bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy and endometrial polyp; however, must be ruled endometrial cancer is the cause in about 10 percent of patients. The gold standard for evaluating the endometrium is transvaginal ultrasonography and endometrial biopsy, which are two key components that help reach an accurate diagnosis.
20
artículo
Postmenopausal women in the presence of abnormal uterine bleeding spontaneously and unexpectedly requires rigorous evaluation to determine the source of the bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy and endometrial polyp; however, must be ruled endometrial cancer is the cause in about 10 percent of patients. The gold standard for evaluating the endometrium is transvaginal ultrasonography and endometrial biopsy, which are two key components that help reach an accurate diagnosis.