Objectives. To determine the relationship between obesity at the beginning, in the second and third trimester of pregnancy and macrosomic newborns treated at the National Maternal Perinatal Institute during the period from 2003 to 2005. Materials and methods. An analytical, prospective study in which it was followed two cohorts of pregnant women, the first one with 210 pregnant with adequate prepregnancy weight or overweight; and the second one with 211 pregnant with prepregnancy maternal obesity. We proceeded to descriptive analysis, through percentages, means and standard deviations. For the determination of hypothesis tests proceeded to significant inferential statistics with an alpha level of statistical significance of less than 0.05. To determine the influence, it proceeded to use the Relative Risk (RR) with confidence intervals at 95%.

Interstitial ectopic pregnancy, misnamed cornual, is a rare pathology, but it implies a high morbidity and mortality if it is notdiagnosed and treated on time. We present the case of a one-year-old patient who attended the emergency room due topain, vaginal bleeding, and a 9-week period of amenorrhea. During the ultrasonographic evaluation, a gestational sac withan active embryo was evidenced at the level of the right uterine horn, for which the diagnosis of cornual ectopic pregnancywas considered and proceeding to perform an abdominal hysterectomy. The best knowledge of the natural history of thedisease, as well as an early and timely diagnosis, is the key to the conservative management of this disease.

Objective. To describe the psychological, social and gynecological characteristics of patients with gestational lossseen at the Instituto Nacional Materno Perinatal (2022). Materials and Methods. This research corresponds to aretrospective descriptive observational study, in which 176 clinical histories of patients with gestational losses duringthe year 2022 attended by the psychology service who met the inclusion and exclusion criteria were collected. Ananalysis of frequencies and percentages of the different variables was performed in order to meet the research objectives. Results. The average age of the patients was 30 years (min: 18 years and max: 46 years), with a mean of 2.64gestations in the sample, a minimum of 0 and a maximum of 4 gestational losses. Fetal death (65.34%) was the mostfrequent diagnosis of fetal death. All the patients presented a psychological disorder, with Brie...

Objectives: To determine the relationship between the average pulsatility index of the uterine arteries taken by ultrasound inpregnant women between 11 and 14 and 20 to 26 weeks of gestation with neonatal macrosomia. Materials and methods:Prospective, longitudinal, analytical study. A total of 3,279 pregnant women attended at the National Maternal Perinatal Institutebetween 2011 and 2014, of whom 952 were patients between 11 and 14 weeks and 2327 between 20 and 26 weeks, two groupswere formed: 11 to 14 and 20 to 26 weeks; The weights considered for the comparison were: 3,600, 3,800, 4,000, 4,200 and 4,400grams, a correlation was performed by the Pearson method, statistical significance was performed by means of Chi square test forboth groups, to calculate the probability Of occurrence of events was calculated odss ratio and to evaluate the precision were usedconfidence intervals, subsequ...

Objective. Misoprostol is an analogous of Prostaglandin E1, used for induction of labor when Bishop score is lower than 6. The goal of the study is to describe la eficacy of 25 μg vaginal misoprostol to induction of labor in term gestantions with live fetus. Also describe others outcomes like way of delivery, characteristics of newborn, adverse maternal and perinatal outcomes. Materials and methods. Descriptive and retrospective study. Population: pregnant women hospitalized in Obstetrics C Unit at Instituto Nacional Materno Perinatal for induction of labor with vaginal misoprostol. Period: may 2009 to march 2010. Data in SPSS version 13 to statistics analysis. Results. 25 μg vaginal misoprostol each 6 hours was administrated to 39 pregnants. Mean age was 27 years. Gestacional age 40 weeks (between 37 to 42). 51% was nulliparous, 92% pregnants had Bishop score lower than 5. It is achie...

Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...

Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...

Intrauterine fetal growth restriction (IUGR), is a clinical circumstance in which the fetus does not express its genetic growth potential and as a final result there is a decrease in body weight, which is below the 10th percentile for gestational age on a selected growth curve. The global prevalence of IUGR according to different authors varies between 3,7% and 22,4%. In Peru they are reported from 4,8% to 10,1%. Obstetric factors associated with IUGR include: pre-eclampsia with OR=1,69 to OR=66,54; anemia during pregnancy OR=2,18 to OR=9,70; Previous IUGR with OR=3,26 at OR=14,49 and preterm delivery with OR=3,58 at OR=14,60.

Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.

Postmenopausal women in the presence of abnormal uterine bleeding spontaneously and unexpectedly requires rigorous evaluation to determine the source of the bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy and endometrial polyp; however, must be ruled endometrial cancer is the cause in about 10 percent of patients. The gold standard for evaluating the endometrium is transvaginal ultrasonography and endometrial biopsy, which are two key components that help reach an accurate diagnosis.

Objective. To determine the clinical and pathological characteristics of the fetus and from the mother in the fetal death of the NationalMaternal Perinatal Institute from 2011 to 2015. Methodology. This is a quantitative, retrospective, observational, descriptive and crosssectionalstudy. Our population is 954 fetuses that died between week 22 of gestation and / or weight greater than 500 gr at the time of birthat the National Maternal Perinatal Institute from 2011 to 2015. Where our sample is 273 and we apply simple random probabilistic sampling.The technique of data collection that is performed is the observation and the instrument are the records where the data (database andmedical history) that has the National Maternal Perinatal Institute are found. The technique for processing the data will be the SPSS StatisticalBase v22.0 program. In the analysis of data will be estimated by frequ...

Objective: To evaluate the obstetric outcome of pregnant women with advanced maternal age (EMA) treated at the NationalMaternal Perinatal Institute. Materials and methods: Observational, descriptive and retrospective study of 321 maternaloutgoings occurred during the period from January 1 to June 30, 2016.

Objective. To identify perinatal outcomes in pregnant women with advanced maternal age (EMA) treated at the NationalMaternal Perinatal Institute. Materials and methods. Observational, descriptive and retrospective study of 321 maternaloutgoings occurred during the period from January 1 to June 30, 2016.

The genitourinary syndrome of menopause clinically is evident 4 to 5 years after menopause, and objective changes arepresent in 25-50% of all postmenopausal women. The most frequent symptoms are vaginal dryness ( 75%), dyspareunia(38%), and vaginal itching, vaginal discharge and pain (15%); and the diagnosis is based on clinical criteria. The principlestherapeutic are based on the restoration of urogenital physiology and relief of symptoms; including non-hormonal / lubricanttherapeutic options, systemic hormonal therapy, local estrogen therapy and other alternatives. The genitourinary syndromeof menopause is one of the most important determinants of sexual function and urogenital health, with a significant impact onthe quality of life related to female health.

Endocervical polyps are the most common benign pathologies of the cervix, whose etiology is still unknown. They appear in 2 to 5% of women. In general they originate in the endocervical canal and less frequently from the ectocervix. The case of a 51-year-old woman whose last menstruation date was 2 years ago is presented and goes to a climacteric office for routine, asymptomatic control and a 1x0,5 cm color polypoid tumor is visualized in the gynecological examination. Pink with shortened sessile pedicle, to whom polypectomy is performed and whose histological study reveals endocervical polyp without signs of malignancy.

The evaluation of quality of life should focus mainly on the patient’s perception of her state of health, being an activeparticipant in this process. Instruments for measuring health-related quality of life (HRQL) can be classified into genericinstruments that measure multiple areas or domains and that are applicable to all individuals, regardless of the pathologythat affects them; And specific instruments, which are those that measure the functioning of the patient in one or severalareas and are characterized by paying particular attention to those symptoms or problems specific to a particular diseaseand those areas considered to be most affected, being only applicable to patients Specific. In daily clinical practice it is usefulto evaluate: improvement of clinical diagnosis, individualization and prioritization of treatments, improving the doctor-patientrelationship, and monitoring c...

Fetal growth restriction (RCF) is a clinical circumstance in which the fetus does not express its genetic potential for growth and as a final result a decrease in body weight occurs, which is below the 10th percentile for gestational age, in a selected growth curve. Among the etiological factors include: maternal, fetal and placental causes. It is classified as Precocious and late. The appropriate time for delivery is determined by gestational age and fetal condition.

Objective: To describe the prevalence and characteristics of seropositive pregnant women for SARS-CoV-2. Material and methods: Quantitative, cross-sectional and descriptive study. Performed in pregnant women screened for SARS-CoV-2 who met selection criteria at hospital admission. Variables of maternal characteristics, pregnancy complications and newborn condition were collected from the respective medical history. Data analysis was performed using descriptive statistics and 95% confidence intervals. Results: 1477 pregnant women admitted to hospitalization were screened, identifying a seroprevalence of anti-SARS-CoV-2 antibodies in 5.28% (95% CI: 4.22% -6.57%). Among the cases of positive seroprevalence, IgM 11.5% (95% CI: 5.7% -21.3%), IgM / IgG 64.1% (95% CI: 5.7% -21.3%), IgG 19% (95% CI: 15.7% and 35.6) were observed %), 91% of seropositive pregnant women were asymptomatic, 40% of se...

Introduction: COVID-19 disease spreads rapidly. Seroprevalence in pregnant women entering for hospitalization and clinical characteristics in this type of population in Peru is not known. Objective: To determine the prevalence and clinical-epidemiological characteristics of pregnant women with anti-SARS-CoV-2 antibodies at a level III hospital in Peru. Methods: Observational and cross-sectional study performed at the National Maternal Perinatal Institute of Peru. Pregnant women admitted for hospitalization were screened for COVID-19 infection. Results of anti-SARSCoV-2 serological tests and information on maternal and perinatal characteristics were obtained. Data analysis was performed using descriptive statistics and 95% confidence intervals. Results: In 2 419 pregnant women screened we identified a prevalence of 7.0% of anti-SARS-CoV-2 antibodies (95% IC: 6.1% to 8.1%), including IgM i...

Introducción. La enfermedad de COVID-19 se propaga rápidamente. Se desconoce la seroprevalencia en mujeres embarazadas que ingresan a hospitalización y sus características propias en este tipo de población en Perú. Objetivo. Determinar la prevalencia y características clínico-epidemiológicas de gestantes con anticuerpos anti-SARS-CoV-2 en un hospital nivel III de Perú. Métodos. Estudio observacional de tipo transversal, realizado en el Instituto Nacional Materno Perinatal de Perú, entre el 15 de abril y 15 de mayo de 2020. Participaron todas las gestantes que ingresaron a hospitalización y fueron tamizadas para la infección por SARS-CoV-2 mediante pruebas serológicas, cuyos resultados fueron analizados conjuntamente con sus características clínicas y epidemiológicas, utilizando estadígrafos descriptivos e intervalos de confianza al 95%, y mediante la prueba de independ...