Objectives. To determine the relationship between obesity at the beginning, in the second and third trimester of pregnancy and macrosomic newborns treated at the National Maternal Perinatal Institute during the period from 2003 to 2005. Materials and methods. An analytical, prospective study in which it was followed two cohorts of pregnant women, the first one with 210 pregnant with adequate prepregnancy weight or overweight; and the second one with 211 pregnant with prepregnancy maternal obesity. We proceeded to descriptive analysis, through percentages, means and standard deviations. For the determination of hypothesis tests proceeded to significant inferential statistics with an alpha level of statistical significance of less than 0.05. To determine the influence, it proceeded to use the Relative Risk (RR) with confidence intervals at 95%.

Interstitial ectopic pregnancy, misnamed cornual, is a rare pathology, but it implies a high morbidity and mortality if it is notdiagnosed and treated on time. We present the case of a one-year-old patient who attended the emergency room due topain, vaginal bleeding, and a 9-week period of amenorrhea. During the ultrasonographic evaluation, a gestational sac withan active embryo was evidenced at the level of the right uterine horn, for which the diagnosis of cornual ectopic pregnancywas considered and proceeding to perform an abdominal hysterectomy. The best knowledge of the natural history of thedisease, as well as an early and timely diagnosis, is the key to the conservative management of this disease.

Objective. To describe the psychological, social and gynecological characteristics of patients with gestational lossseen at the Instituto Nacional Materno Perinatal (2022). Materials and Methods. This research corresponds to aretrospective descriptive observational study, in which 176 clinical histories of patients with gestational losses duringthe year 2022 attended by the psychology service who met the inclusion and exclusion criteria were collected. Ananalysis of frequencies and percentages of the different variables was performed in order to meet the research objectives. Results. The average age of the patients was 30 years (min: 18 years and max: 46 years), with a mean of 2.64gestations in the sample, a minimum of 0 and a maximum of 4 gestational losses. Fetal death (65.34%) was the mostfrequent diagnosis of fetal death. All the patients presented a psychological disorder, with Brie...

Objectives. To determine the relationship between obesity at the beginning, in the second and third trimester of pregnancy and macrosomic newborns treated at the National Maternal Perinatal Institute during the period from 2003 to 2005. Materials and methods. An analytical, prospective study in which it was followed two cohorts of pregnant women, the first one with 210 pregnant with adequate prepregnancy weight or overweight; and the second one with 211 pregnant with prepregnancy maternal obesity. We proceeded to descriptive analysis, through percentages, means and standard deviations. For the determination of hypothesis tests proceeded to significant inferential statistics with an alpha level of statistical significance of less than 0.05. To determine the influence, it proceeded to use the Relative Risk (RR) with confidence intervals at 95%.

Interstitial ectopic pregnancy, misnamed cornual, is a rare pathology, but it implies a high morbidity and mortality if it is notdiagnosed and treated on time. We present the case of a one-year-old patient who attended the emergency room due topain, vaginal bleeding, and a 9-week period of amenorrhea. During the ultrasonographic evaluation, a gestational sac withan active embryo was evidenced at the level of the right uterine horn, for which the diagnosis of cornual ectopic pregnancywas considered and proceeding to perform an abdominal hysterectomy. The best knowledge of the natural history of thedisease, as well as an early and timely diagnosis, is the key to the conservative management of this disease.

Objectives: To determine the relationship between the average pulsatility index of the uterine arteries taken by ultrasound inpregnant women between 11 and 14 and 20 to 26 weeks of gestation with neonatal macrosomia. Materials and methods:Prospective, longitudinal, analytical study. A total of 3,279 pregnant women attended at the National Maternal Perinatal Institutebetween 2011 and 2014, of whom 952 were patients between 11 and 14 weeks and 2327 between 20 and 26 weeks, two groupswere formed: 11 to 14 and 20 to 26 weeks; The weights considered for the comparison were: 3,600, 3,800, 4,000, 4,200 and 4,400grams, a correlation was performed by the Pearson method, statistical significance was performed by means of Chi square test forboth groups, to calculate the probability Of occurrence of events was calculated odss ratio and to evaluate the precision were usedconfidence intervals, subsequ...

Objectives: To determine the relationship between the average pulsatility index of the uterine arteries taken by ultrasound inpregnant women between 11 and 14 and 20 to 26 weeks of gestation with neonatal macrosomia. Materials and methods:Prospective, longitudinal, analytical study. A total of 3,279 pregnant women attended at the National Maternal Perinatal Institutebetween 2011 and 2014, of whom 952 were patients between 11 and 14 weeks and 2327 between 20 and 26 weeks, two groupswere formed: 11 to 14 and 20 to 26 weeks; The weights considered for the comparison were: 3,600, 3,800, 4,000, 4,200 and 4,400grams, a correlation was performed by the Pearson method, statistical significance was performed by means of Chi square test forboth groups, to calculate the probability Of occurrence of events was calculated odss ratio and to evaluate the precision were usedconfidence intervals, subsequ...

Objective. To describe the psychological, social and gynecological characteristics of patients with gestational lossseen at the Instituto Nacional Materno Perinatal (2022). Materials and Methods. This research corresponds to aretrospective descriptive observational study, in which 176 clinical histories of patients with gestational losses duringthe year 2022 attended by the psychology service who met the inclusion and exclusion criteria were collected. Ananalysis of frequencies and percentages of the different variables was performed in order to meet the research objectives. Results. The average age of the patients was 30 years (min: 18 years and max: 46 years), with a mean of 2.64gestations in the sample, a minimum of 0 and a maximum of 4 gestational losses. Fetal death (65.34%) was the mostfrequent diagnosis of fetal death. All the patients presented a psychological disorder, with Brie...

Objective. Misoprostol is an analogous of Prostaglandin E1, used for induction of labor when Bishop score is lower than 6. The goal of the study is to describe la eficacy of 25 μg vaginal misoprostol to induction of labor in term gestantions with live fetus. Also describe others outcomes like way of delivery, characteristics of newborn, adverse maternal and perinatal outcomes. Materials and methods. Descriptive and retrospective study. Population: pregnant women hospitalized in Obstetrics C Unit at Instituto Nacional Materno Perinatal for induction of labor with vaginal misoprostol. Period: may 2009 to march 2010. Data in SPSS version 13 to statistics analysis. Results. 25 μg vaginal misoprostol each 6 hours was administrated to 39 pregnants. Mean age was 27 years. Gestacional age 40 weeks (between 37 to 42). 51% was nulliparous, 92% pregnants had Bishop score lower than 5. It is achie...

Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...

Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...

Objective. Misoprostol is an analogous of Prostaglandin E1, used for induction of labor when Bishop score is lower than 6. The goal of the study is to describe la eficacy of 25 μg vaginal misoprostol to induction of labor in term gestantions with live fetus. Also describe others outcomes like way of delivery, characteristics of newborn, adverse maternal and perinatal outcomes. Materials and methods. Descriptive and retrospective study. Population: pregnant women hospitalized in Obstetrics C Unit at Instituto Nacional Materno Perinatal for induction of labor with vaginal misoprostol. Period: may 2009 to march 2010. Data in SPSS version 13 to statistics analysis. Results. 25 μg vaginal misoprostol each 6 hours was administrated to 39 pregnants. Mean age was 27 years. Gestacional age 40 weeks (between 37 to 42). 51% was nulliparous, 92% pregnants had Bishop score lower than 5. It is achie...

Objective. To evaluate the changes that have occurred from 2012 to 2017, and analyze the factors that influence them. Materials and Methods. The maternal-perinatal statistical database managed by the National Maternal Perinatal Institute was analyzed. All those births belonging to Metropolitan Lima, born alive, of single births were included, obtaining a total of 107,581 deliveries. A multivariate analysis was performed adjusting for different obstetric and socioeconomic variables. Results. There were no significant changes in Low Birth Weight, Preterm Birth and PEG between the different years. In all three cases, mild anemia is playing as a protective factor 0.91 (0.74-1.1), 0.80 (0.72-0.90) and 0.85 (0.76-0.95), respectively. While pre-eclampsia is the most influential risk factor, OR: 2.90 (2.25-3.73), 5.23 (4.61-5.98) and 3.00 (2.57-3.49), respectively. Conclusion. The risk of Low Bi...

Objetivo: Determinar las características clínicas de la infección vulvovaginal por Candida albicans (CVV) en mujeres en edad reproductiva.  Materiales y métodos: Investigación observacional, descriptiva, retrospectiva y transversal. Se incluyó una muestra de 120 mujeres con diagnóstico de infección vulvovaginal por Candida Albicans atendidas en consulta externa en el Instituto Nacional Materno Perinatal periodo 2018. Resultados: La prevalencia de infección vulvovaginal por Candida albicans fue 28%. Las características sociodemográficas fueron, edad mediana con 53,3%, estado civil conviviente 39,2%, instrucción superior 49,2% y ama de casa 53,3%. Respecto a las características ginecológicas incluyeron número de parejas sexuales 2,1±0,8, uso de anticonceptivo depoprovera con 35% y anticonceptivo oral combinado 28,3%; hábitos de higiene íntima ocasional 61,7%.  L...

Intrauterine fetal growth restriction (IUGR), is a clinical circumstance in which the fetus does not express its genetic growth potential and as a final result there is a decrease in body weight, which is below the 10th percentile for gestational age on a selected growth curve. The global prevalence of IUGR according to different authors varies between 3,7% and 22,4%. In Peru they are reported from 4,8% to 10,1%. Obstetric factors associated with IUGR include: pre-eclampsia with OR=1,69 to OR=66,54; anemia during pregnancy OR=2,18 to OR=9,70; Previous IUGR with OR=3,26 at OR=14,49 and preterm delivery with OR=3,58 at OR=14,60.

Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.

Objective: determine if gestation in advanced maternal age is associated with a higher risk of maternal perinatal complicationsthan in adolescent gestation. Materials and methods: observational, correlational, retrospective, cross-sectional study wascarried out with a population of 6475 pregnant women and 7645 pregnant women attended at the National Maternal PerinatalInstitute who have been controlled and culminated in the institution in the period between January From 2012 to December2015.

Postmenopausal women in the presence of abnormal uterine bleeding spontaneously and unexpectedly requires rigorous evaluation to determine the source of the bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy and endometrial polyp; however, must be ruled endometrial cancer is the cause in about 10 percent of patients. The gold standard for evaluating the endometrium is transvaginal ultrasonography and endometrial biopsy, which are two key components that help reach an accurate diagnosis.

Postmenopausal women in the presence of abnormal uterine bleeding spontaneously and unexpectedly requires rigorous evaluation to determine the source of the bleeding. The most common cause of postmenopausal bleeding is endometrial atrophy and endometrial polyp; however, must be ruled endometrial cancer is the cause in about 10 percent of patients. The gold standard for evaluating the endometrium is transvaginal ultrasonography and endometrial biopsy, which are two key components that help reach an accurate diagnosis.

Restricción del crecimiento fetal intrauterino (RCIU), es una circunstancia clínica en la cual el feto no expresa su potencial genético de crecimiento y como resultado final ocurre una disminución en el peso corporal, el cual queda por debajo del percentil 10 para la edad gestacional, en una curva de crecimiento seleccionada. La prevalencia global de RCIU según distintos autores varía entre 3,7% a 22,4%. En el Perú se reportan del 4,8% al 10,1%. Los factores obstétricos asociados a RCIU destacan: preeclampsia con OR=1,69 al OR=66,4; anemia durante la gestación OR=2,18 al OR=9,70; RCIU previa con OR=3,26 al OR=14,49 y parto pretérmino con OR=3,58  al  OR=14,60.