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1
artículo
Publicado 2022
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Infectious bursal disease is a pathology of viral origin that affects poultry, causing a high mortality rate. Existing vaccines face the problem of the appearance of new strains, so searches are made for molecules with potential binding affinity to viral proteins. Withania somnifera extract is involved in the replication of infectious bursitis virus, but the possible mechanism of action is not well understood. The aim of this study was to identify, through in silico methods, the phytoconstituents of W. somnifera with binding affinity to the active site of viral protein 1 (VP1) of infectious bursal disease virus. Molecular docking assays were performed between VP1 and 27 phytoconstituents described in W. somnifera. The binding energy data obtained were analysed with the Kruskal-Wallis test and Dunn’s test (p<0.05). The results showed that the compounds somniferin, withanolide A, with...
2
artículo
Publicado 2020
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This paper deals with the automation of psychological assessments to help to select the right candidate for the organization during the recruitment process on a human resources consulting firm. The solution was developed with Kanban Method and cloud computing, such as Amazon Web Services (AWS), where it was integrated and launched with other services to improve security and operativity. Experiments were divided into functionalities: (1) an interface for mobile phones and (2) notifying recruiter by SMS and Email when candidate finalize the tests. The results show improved recruiter response time to analyze test results and prepare psychological reports in two and a half months. The recruiter's performance increased by up to 5% in person-hours.
3
artículo
Publicado 2019
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When we refer to pain, we are faced with an unpleasant sensation that causes certain reactions in the human body that prevent its production, so it is of vital importance to understand what the symptomatology of pain is, how it is produced and how it can be avoided. production, there are cases where the pain becomes pathological where found in the patient's thoughts, therefore the present work tries to demonstrate that its production can be avoided in the face of intense painful situations that occur when working in the recovery of the mobility of the patient. articulation of the knee, which by its nature is painful, added to the fear of feeling pain on the part of the patient does not help the patient's recovery, the experimentation consists of taking the pain from the approach of not thinking about it and relaxing and evaluating it by an environment of cerebral analysis through the lev...
4
artículo
Publicado 2020
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Methylmercury (MeHg+) is a mercury species that is very toxic for humans, and its monitoring and sorption from environmental samples of water are a public health concern. In this work, a combination of theory and experiment was used to rationally synthesize an ion-imprinted polymer (IIP) with the aim of the extraction of MeHg+ from samples of water. Interactions among MeHg+ and possible reaction components in the pre-polymerization stage were studied by computational simulation using density functional theory. Accordingly, 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and ethanol were predicted as excellent sulfhydryl ligands, a functional monomer and porogenic solvent, respectively. Characterization studies by scanning electron microscopy (SEM) and Brunauer–Emmett–Teller (BET) revealed the obtention of porous materials with specific surface areas...
5
artículo
Publicado 2023
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This work was carried out by the importance of providing insights into the nano-based drug delivery of anticancers. To this aim, a representative model of aluminum nitride (AN) nanocage scaffold and two of its boron and gallium doped forms (BAN and GAN) were investigated towards the adsorption of thiotepa (Tep) anticancer. Density functional theory (DFT) calculations were performed to evaluate the stabilized structures and their corresponding electronic features. The results indicated the contribution of N-head and S-head of Tep to interactions with each scaffold resulting six complexes; NTep@AN and STep@AN, NTep@BAN and STep@BAN, NTep@GAN and STep@GAN. In each complex model, the characteristic features were obtained based on the interactions details and frontier molecular orbitals related features. In this regard, the investigated scaffolds were found suitable for adsorbing the Tep subs...
6
artículo
Publicado 2023
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Inertial kinetics and kinematics have substantial influences on human biomechanical function. A new algorithm for Inertial Measurement Unit (IMU)-based motion tracking is presented in this work. The primary aims of this paper are to combine recent developments in improved biosensor technology with mainstream motion-tracking hardware to measure the overall performance of human movement based on joint axis-angle representations of limb rotation. This work describes an alternative approach to representing three-dimensional rotations using a normalized vector around which an identified joint angle defines the overall rotation, rather than a traditional Euler angle approach. Furthermore, IMUs allow for the direct measurement of joint angular velocities, offering the opportunity to increase the accuracy of instantaneous axis of rotation estimations. Although the axis-angle representation requi...
7
tesis de grado
Publicado 2019
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A través de la presente tesis titulada “Implementación de un sistema contable y su incidencia en la toma de decisiones gerenciales en Faminox S.R.L” tiene como objetivo principal demostrar que con la implementación y formulación de un sistema de información contable mejorará positivamente en la gestión de la contabilidad para la toma de decisiones gerenciales. El sistema de información contable que se implementa en Faminox S.R.L como una propuesta es el CONCAR SQL. En el proceso de la tesis se evaluará los aspectos generales sobre el planeamiento del problema que se identifica con el objetivo de analizar, buscar información y dar diagnóstico preciso para un resultado oportuno. Para dar a conocer las situaciones que provocan estas incidencias se ha aplicado un instrumento: guía de entrevista. En conclusión que la gerencia debe desarrollar capacitar permanente al personal ...
8
artículo
Publicado 2020
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In this paper, a three-dimensional numerical solution for the bending study of laminated composite doubly-curved shells is presented. The partial differential equations are solved analytically by the Navier summation for the midsurface variables; this method is only valid for shells with constant curvature where boundary conditions are considered simply supported. The partial differential equations present different coefficients, which depend on the thickness coordinates. A semi-analytical solution and the so-called Differential Quadrature Method are used to calculate an approximated derivative of a certain function by a weighted summation of the function evaluated in a certain grin domain. Each layer is discretized by a grid point distribution such as: Chebyshev-Gauss-Lobatto, Legendre, Ding and Uniform. As part of the formulation, the inter-laminar continuity conditions of displacement...
9
artículo
Publicado 2020
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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
10
tesis de grado
Publicado 2022
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El presente trabajo presenta como objetivo determinar como la implementación del Sistema Móvil mejorará la gestión de soporte de TI para la empresa FTS E.I.R.L. Acerca de la gestión de atención al cliente, gestión de índice de productividad y gestión de eficiencia de procesos. La empresa FTS E.I.R.L. actualmente cuenta con un sistema de manejo de los procesos de soporte de TI deficiente; no obstante, dicho sistema presenta algunos errores en su funcionamiento, lo cual afecta considerablemente a las áreas de consultas y de atención. Esto se debe principalmente por la demora en la atención a clientes, ocasionando dificultades en la búsqueda de productos, pérdidas de productos y un deficiente flujo de negocio del sistema actual. El soporte de TI cubre todos los servicios que asisten en el buen uso, mantenimiento e implementación de los recursos técnicos de la empresa. Se pue...
11
tesis de grado
Publicado 2017
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The main challenge for Peruvian SMEs is obtaining information for decision making. In this context, the use of data analysis technologies such as Business Intelligence and Analytics are not very accessible to companies, due to economic and human capital limitations. The main objective of the project is the implementation of a technological model that combines Business Intelligence and Analytics with Cloud Computing, to allow retail SMEs to integrate and process their data to make informed and timely decisions regarding inventory planning and management, with a low cost of implementation and deployment. For the development of the project, a preliminary investigation is carried out about Business Intelligence, Analytics and Cloud Computing technologies, where the applications of each one is studied and success cases of retail SMEs worldwide. Then, the technological model oriented to the ne...
12
artículo
Publicado 2023
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The video game industry has undergone one of the most significant transformations in recent times. This is reflected not only in the economic aspect but also in the increasing number of players who want to explore and interact in the world of video games in recent years. As for the Real-Time Strategy (RTS) genre, which reached its peak in the early 2000s, it did not continue to see the same trend in game development, and the population of active players has been declining [1]. The primary reason for this continuous decline is the competition from games in other genres such as First Person Shooter (FPS), Multiplayer Online Battle Arena (MOBA), and other genres with attractive characteristics that set them apart. In response to this, a solution is offered, which involves the development of a multiplayer RTS video game for Windows operating systems (PC), with the aim of generating greater i...
13
artículo
Publicado 2019
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The task of elaborating accurate test suites for program testing can be an extensive computational work. Mutation testing is not immune to the problem of being a computational and time-consuming task so that it has found relief in the use of heuristic techniques. The use of Genetic Algorithms in mutation testing has proved to be useful for probing test suites, but it has mainly been enclosed only in the field of imperative programming paradigms. Therefore, we decided to test the feasibility of using Genetic Algorithms for performing mutation testing in functional programming environments. We tested our proposal by making a graph representations of four different functional programs and applied a Genetic Algorithm to generate a population of mutant programs. We found that it is possible to obtain a set of mutants that could find flaws in test suites in functional programming languages. Ad...
14
artículo
Publicado 2020
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Methylmercury (MeHg+) is a mercury species that is very toxic for humans, and its monitoring and sorption from environmental samples of water are a public health concern. In this work, a combination of theory and experiment was used to rationally synthesize an ion-imprinted polymer (IIP) with the aim of the extraction of MeHg+ from samples of water. Interactions among MeHg+ and possible reaction components in the pre-polymerization stage were studied by computational simulation using density functional theory. Accordingly, 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and ethanol were predicted as excellent sulfhydryl ligands, a functional monomer and porogenic solvent, respectively. Characterization studies by scanning electron microscopy (SEM) and Brunauer–Emmett–Teller (BET) revealed the obtention of porous materials with specific surface areas...
15
tesis de maestría
Publicado 2024
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Parque Eterno es una empresa de servicios fúnebres con más de 20 años en el mercado. Su proceso de gestión de contratos ha venido evolucionando de forma lenta debido a factores culturales y generacionales respecto al tipo de cliente. Este proceso inicialmente era totalmente manual y en veinte años solo ha evolucionado a un porcentaje manual mediante el uso de algunos formatos y a otro automatizado mediante el uso de un sistema de escritorio. Con la llegada del COVID-19, la alta demanda y el aumento desmedido de uso de los servicios hicieron colapsar este proceso de gestión de contratos. El presente trabajo tuvo por finalidad mejorar la gestión de contratos de la empresa Parque Eterno. Para ello se propuso el desarrollo e implementación de un nuevo sistema con una nueva tecnología. El objetivo fue determinar el impacto de la implementación de este nuevo sistema en la gestión de...
16
tesis de grado
Publicado 2018
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La Empresa Nacional de Telecomunicaciones – ENTEL PERU ha tenido inconvenientes para llevar a cabo sus actividades para resolver problemas informáticos a nivel de hardware y software dentro de las áreas de gerencia, desarrollo, plataforma, contabilidad y monitoreo ya que no cuentan con una aplicación para reportar sus incidencias al área de soporte técnico, lo que ocasiona dificultades en el ambiente laboral; por consiguiente, el objetivo del presente trabajo es determinar la influencia del desarrollo de una aplicación web en la gestión de incidencias en la Empresa Nacional de Telecomunicaciones. Para ello, como solución tecnológica es desarrollar una aplicación web utilizando la metodología RUP para mejorar la gestión de incidencias y a su vez recuperar el nivel habitual de funcionamiento de forma que la calidad del servicio y la disponibilidad se mantengan. Los resultados...
17
artículo
Publicado 2024
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Business sustainability has become a global imperative in response to the environmental, social, and economic challenges facing our world. In this context, the measurement and evaluation of business sustainability have become crucial to guide the actions of organizations towards more responsible and sustainable practices. However, the lack of specific measurement instruments for specific regional contexts may limit the ability of companies to evaluate and improve their sustainability performance. In this paper, we present the design of a business sustainability measurement method adapted to the context of Tarma, Peru. Tarma, a region located in the heart of the Peruvian Andes, is characterized by its cultural, environmental, and economic diversity, making it a unique context to address business sustainability. This article proposes a method for measuring business sustainability based on ...
18
artículo
Publicado 2019
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ATMs are widely used around the world, which leads to the development of new functionalities that need to consider usability. For this reason, the following article presents the development of graphical interfaces for ATM of BBVA Continental Bank, which follows a user-centered process design. In the first place, we gathered information about our target user. Then, we developed a prototype based on the previous information and the needs of the bank, which also took into account expert’s feedback. Finally, real users in the bank itself validated the prototypes.
19
artículo
Publicado 2023
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Currently due to the pandemic situation that has affected the world community without distinction of languages, customs and creeds, technology was incorporated massively to achieve the continuity of progress in research, and development of culture and academic education, through this progress. As an introduction we can mention that this research is achieved by the need to do physics using other tools easy to manipulate with basic programming knowledge, likewise in the repositories there are many other studies that applied computationally the development of simulations of different physical phenomena. The method to use is the GeoGebra tools applying the basic syntax that is obtained by entering the equations in the input bar of the GeoGebra software already preset, being these equations calculated many times by students using differential equations, which obtains the solution equation dep...
20
objeto de conferencia
Presentación que se llevó a cabo durante el VI Congreso Internacional de Computación y Telecomunicaciones COMTEL 2014 del 22 al 25 de octubre de 2014 en Lima, Perú. COMTEL, es un certamen organizado por la Facultad de Ingeniería de Sistemas, Cómputo y Telecomunicaciones de la Universidad Inca Garcilaso de la Vega, que congrega a profesionales, investigadores y estudiantes de diversos países con el fin de difundir e intercambiar conocimientos, mostrar experiencias académicas-científicas y soluciones para empresas en las áreas de Computación, Telecomunicaciones y disciplinas afines.
