1
otro
Publicado 2023
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La sepsis todavía es considerada una condición potencialmente mortal y un reto para las unidades de cuidados intensivos, ya que, aunque existen varias escalas que miden el riesgo de mortalidad son pocos los estudios desarrollados para evaluar la relación entre el riesgo nutricional y la mortalidad después de enfermedad crítica. El puntaje de Riesgo Nutricional en Enfermedad Crítica (Nutricional Risk in Critically ill patients: NUTRIC score), nos permite identificar que pacientes pueden beneficiarse de un soporte nutricional, con el fin de modificar el curso de la enfermedad y disminuir la mortalidad esperada en ellos. Objetivo: El presente estudio se realizó para identificar la tasa de mortalidad relacionada al riesgo nutricional en pacientes con UCI con shock séptico en base al puntaje NUTRIC modificado (mNUTRIC). Metodología: Se realizó un estudio de tipo retrospectivo, obser...
2
tesis de grado
Publicado 2017
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RESUMEN La presente investigación tuvo como finalidad determinar la relación entre la procrastinación académica y la autoeficacia en estudiantes de psicología de una universidad privada de Trujillo. La muestra, fue obtenida mediante un proceso probabilístico estratificado, conformada por 188 estudiantes de psicología, quienes fueron evaluados a través de los instrumentos: la Escala de Procrastinación Académica EPA (Busko 1998, validado por Dominguez, 2014) y la Escala de Autoeficacia General - EAG (Baessler & Schwarzer 1996). El estudio concluyó que existe una correlación negativa altamente significativa (-0.236**) entre procrastinación académica y autoeficacia. Asimismo, los resultados revelaron una relación positiva altamente significativa (0.287**) entre el factor de autorregulación académica y autoeficacia; sin embargo no se halló relación con el factor de posterga...
3
otro
Publicado 2023
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La neuropatía diabética (ND) es un conjunto de signos y/o síntomas dentro de una alteración de nervios periféricos en personas diabéticas, descartando otras posibles causas. El desarrollo de ND se da alrededor del 40 al 50%, esto dentro de los 10 años del inicio de la enfermedad en diabéticos tipo I como en tipo II. Sin embargo, de este grupo, solo el 50% hacen sintomatología. Por ende, la prevalencia asciende con el transcurso de los años, así como el tiempo de duración con cifras de elevadas de glicemia. En el HRDCQ Daniel Alcides Carrión se ha comprobado que la neuropatía influye en el modo de vida del paciente, ya que es resistente a diversas medicaciones. El adecuado control o identificación de los factores de riesgo ha demostrado una reducción notoria de complicaciones a nivel microvascular. No obstante, hay otros factores como el diagnóstico tardío, tratamiento a...
4
artículo
Publicado 2024
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Purpose: The main purpose of this paper is to analyse the influence of capital efficiency on the economic growth of Bangladesh using the Harrod-Domar (H-D) model. Design/methodology/approach: We use annual data from 1980 to 2019 for this paper. Three steps are taken in the data analysis. First, to check the existence of a unit root, we use the augmented Dickey-Fuller (ADF) test and to determine co-integration among the variables, we use the Johansen-Juselius co-integration test. Next, for long-run estimation, we use the dynamic ordinary least square (DOLS) estimator. The sensitivity of the long-run estimations is further checked by the fully modified OLS (FMOLS) and autoregressive distributed lag (ARDL) estimators. Lastly, we use the Granger causality test to determine the long-run causality among the variables. Findings: The long-run co-integration test validates the co-integrating rela...
5
artículo
Publicado 2022
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Methylmercury (MeHg) is one of the most toxic organic mercury compounds found in the environment. The continuous exposure of human beings to this highly toxic compound may damage their nervous system. The present work reports the development and application of a novel electrochemical sensing technique for the quantification of MeHg using a modified carbon paste electrode with multi-walled carbon nanotubes (MWCNTs) combined with ion imprinted polymer, which is highly selective toward MeHg (CPE/MWCNTs/IIP-MeHg) detection. The ion imprinted polymer was synthesized using 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and MeHg employed as ligand, functional monomer and template ion, respectively, and the synthesized material was characterized by Raman spectroscopy and SEM-EDX. Both the proposed and control sensors were characterized by cyclic voltammetry (CV) and electrochemical impedance s...
6
artículo
Publicado 2021
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An electrochemical sensor (CPE-IIHP) was developed for Cd(II) using a carbon paste electrode (CPE) impregnated with an ion-imprinted hybrid polymer (IIHP). A CPE-NIHP was also prepared for comparison. DPASV was used to optimize the sensor response and quantify Cd(II). The sensor presented a wide linear range from low concentrations of Cd(II): 1 to 100 ?g L?1 and high concentrations of Cd(II): 2.75 to 5.0 mg L?1. Ions such as Co(II), Pb(II), Ni(II), Zn(II), Fe(II), Fe(III), Sn(II) and Cu(II), showed no variation in the Cd(II) signal. The CPE-IIHP was successfully applied in river and drinking water analysis, revealing the great potential for its application.
7
artículo
Publicado 2021
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This work describes an electrochemical sensor for the selective recognition and quantification of amoxicillin and a β-lactam antibiotic in real samples. This sensor consists of a carbon paste electrode (CPE) modified with mag-MIP (magnetic molecularly imprinted polymer), which was prepared by precipitation method via free radical using acrylamide (AAm) as functional monomer, N,N′-methylenebisacrylamide (MBAA) as a crosslinker, and potassium persulfate (KPS) as initiator, to functionalized magnetic nanoparticles. The magnetic non-imprinted polymers (mag-NIP) were prepared using the same experimental procedure without analyte and used for the preparation of a CPE for comparative studies. The morphological, structural, and electrochemical characteristics of the nanostructured material were evaluated using Field emission gun scanning electron microscopy (FEG-SEM), Transmission electron mi...
8
artículo
Publicado 2025
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This study examined the feasibility of removing dexamethasone (DEX) from aqueous solutions using molecularly imprinted polymers (MIPs). The binding energy, used to evaluate the affinity between imprinted molecule and functional monomer, was calculated for DEX using molecular simulation via the density functional theory method. From this approach, three different functional monomers were tested: methacrylic acid, N-(Hydroxymethyl) acrylamide, and 2-hydroxyethyl methacrylate designated as MIP-DEX1, MIP-DEX2, MIP-DEX3, respectively. All of them were prepared by the precipitation polymerization method, with trimethylolpropane trimethacrylate used as the crosslinker. Moreover, the kinetics of adsorption and adsorption isotherms were evaluated using different models to assess the adsorption mechanisms of DEX on polymers. The results showed that equilibrium between the polymer and DEX is reache...
9
artículo
Publicado 2021
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This project was supported by FONDECYT-BM (grant #0232019-FONDECYT-BM-IN.INV), FAPESP (grants #2019/006777 and #2014/50945-4), CNPq (grants #301728/2019-4, #408050/2018-7 and #465571/2014-0), and CAPES (PROJ. AUX/PE/PROEX N. 0674/2018). RL and GP received financial support from the OGI, Research Management Bureau (Project FC-F-6-2018).
10
artículo
Publicado 2021
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The present work shows the synergistic application of reflectance spectroscopy and core-shell molecularly imprinted polymer (MIP) for rapid quantification of tartrazine in soft drinks. Studies evaluated the performance of the MIPs synthesized in the presence of silica nanoparticles unfunctionalized and functionalized with [3-(methacryloyloxy)propyl]trimethoxysilane. Although the use of functionalized silica nanoparticles promoted the highest adsorption capability of tartrazine, the material was found to be less selective when it was applied in real samples. Interestingly, the most accurate results were obtained via the application of the MIP synthesized in the presence of unfunctionalized silica nanoparticles (SiO2@MIP). The optimized core-shell MIP was also characterized by Raman spectroscopy and scanning electron microscopy. The use of direct reflectance spectroscopy in the analyte det...
11
artículo
Publicado 2023
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The present study reports the development and application of a rapid, low-cost in-situ method for the quantification of tartrazine in carbonated beverages using a smartphone-based colorimetric device with molecularly imprinted polymer (MIP). The MIP was synthesized using the free radical precipitation method with acrylamide (AC) as the functional monomer, N,N′-methylenebisacrylamide (NMBA) as the cross linker, and potassium persulfate (KPS) as radical initiator. The smartphone (RadesPhone)-operated rapid analysis device proposed in this study has dimensions of 10 × 10 × 15 cm and is illuminated internally by light emitting diode (LED) lights with intensity of 170 lux. The analytical methodology involved the use of a smartphone camera to capture images of MIP at various tartrazine concentrations, and the subsequent application of the Image-J software to calculate the red, green, blue ...
12
artículo
Publicado 2020
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Two new ionic imprinted hybrid polymers (IIHP) and their corresponding non imprinted hybrid polymers (NIHP) were synthesized. The prepared IIHP was highly selective to Cd2+. To prepare the IIHP, 1-vinylimidazole (VIN) was used as the functional monomer, (3-mercaptopropyl) trimethoxysilane (MP) or (3-aminopropyl) trimethoxysilane (AMP) was used as the functional organosilane, trimethylolpropane (TRIM) was used as the crosslinking agent, AIBN was used as a radical initiator and TEOS was used as a functional precursor. The functional monomer was selected considering calculations based on the density functional theory (DFT). The fabricated materials were characterized via field emission gun scanning electron microscopy (FEG-SEM), Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX) and thermogravimetric analysis (TGA). The maximum adsorption capacity of ...
13
artículo
Publicado 2021
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The present work reports the successful synthesis of a novel Pb2+ ion-imprinted polymer (Pb-IIP) based on a rhodizonate-like selective ligand by precipitation. Three functional monomers, namely acid acrylic (ACRY), 2-acrylamido-2-methylpropane sulfonic acid (AMPSA) and allylamine (ALLY), were chosen by computer simulation using density functional theory (DFT). The materials obtained were applied for the selective removal of Pb2+ from aqueous solutions and were characterized by Fourier transform Infra-red (FTIR), scanning electronic microscopy (SEM) and flame atomic absorption spectrometry (FAAS). The results obtained from the adsorption experiments performed under optimal conditions were in good agreement with the computational design and showed that IIP-AMPSA exhibited a relatively higher adsorption capacity for Pb2+ (51.84 mg g?1) than IIP–ACRY (31.02 mg g?1) and IIP-ALLY (12.90 mg g...
14
artículo
Publicado 2024
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This work describes the preparation of a molecularly imprinted polymer (MIP) platform on polyethylene terephthalate (MIP-PET) via RAFT polymerization for analyzing tartrazine using a smartphone. The MIP-PET platform was characterized using Fourier transform infrared (FTIR) techniques, Raman Spectroscopy, X-ray photoelectron spectroscopy (XPS), and confocal microscopy. The optimal pH and adsorption time conditions were determined. The adsorption capacity of the MIP-PET plates with RAFT treatment (0.057 mg cm−2) was higher than that of the untreated plates (0.028 mg cm−2). The kinetic study revealed a pseudo-first-order model with intraparticle diffusion, while the isotherm study indicated a fit for the Freundlich model. Additionally, the MIP-PET demonstrated durability by maintaining its adsorption capacity over five cycles of reuse without significant loss. To quantify tartrazine, im...
15
artículo
Publicado 2004
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Hepatitis C virus (HCV) has high genomic variability and, since its discovery, at least six different types and an increasing number of sub-types have been reported. There is not knowledge about the degree of genetic variation among HCV strains circulating in the Andean region of South America. In order to study the degree of genetic variability of strains isolated at the HNERM, in this preliminary study it was obtained the sequences from the 5’ non coding region (5’ NCR) belonging to 12 patients and were reported to the GenBank obtaining the accession identifications.
16
artículo
Publicado 2020
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Methylmercury (MeHg+) is a mercury species that is very toxic for humans, and its monitoring and sorption from environmental samples of water are a public health concern. In this work, a combination of theory and experiment was used to rationally synthesize an ion-imprinted polymer (IIP) with the aim of the extraction of MeHg+ from samples of water. Interactions among MeHg+ and possible reaction components in the pre-polymerization stage were studied by computational simulation using density functional theory. Accordingly, 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and ethanol were predicted as excellent sulfhydryl ligands, a functional monomer and porogenic solvent, respectively. Characterization studies by scanning electron microscopy (SEM) and Brunauer–Emmett–Teller (BET) revealed the obtention of porous materials with specific surface areas...
17
artículo
Publicado 2020
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Methylmercury (MeHg+) is a mercury species that is very toxic for humans, and its monitoring and sorption from environmental samples of water are a public health concern. In this work, a combination of theory and experiment was used to rationally synthesize an ion-imprinted polymer (IIP) with the aim of the extraction of MeHg+ from samples of water. Interactions among MeHg+ and possible reaction components in the pre-polymerization stage were studied by computational simulation using density functional theory. Accordingly, 2-mercaptobenzimidazole (MBI) and 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and ethanol were predicted as excellent sulfhydryl ligands, a functional monomer and porogenic solvent, respectively. Characterization studies by scanning electron microscopy (SEM) and Brunauer–Emmett–Teller (BET) revealed the obtention of porous materials with specific surface areas...
18
artículo
Publicado 2023
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Addressing the global challenge of sustainable waste management, this research investigates the influence of social dynamics and digital connectivity on rural residents’ willingness to adopt waste classification practices, essential for sustainable environmental management. Through a comprehensive analysis of 5413 rural participants surveyed in the China Labor-force Dynamic Survey (CLDS), this study employs a novel mixed-methods approach. It integrates quantitative analysis with the Manski social interaction framework and a Recursive Bivariate Probit model to explore the intricate interplay between community interactions, internet access, and environmental behaviors. Our methodology stands out for its unique combination of social theory and econometric modeling to address a pressing environmental issue. Results highlight a significant effect of mobile internet use and social interactio...
19
artículo
Publicado 2025
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Multiple sclerosis (MS) is a chronic autoimmune condition causing damage to the protective covering of nerves in the central nervous system. Pediatric multiple sclerosis is a rare form of the disease that affects 3-5% of individuals with multiple sclerosis. Pediatric Onset Multiple Sclerosis (POMS) has a rather different clinical profile from the more prevalent adult multiple sclerosis. Alongside the classic symptoms of multiple sclerosis, children tend to present with various atypical symptoms that can impact motor milestones, speech development, and cognitive functions. This review aims to explore the pathogenesis, clinical features, diagnosis and progression of Pediatric Onset Multiple Sclerosis into adulthood, address the challenges accompanying this transition and identify strategies and therapies to overcome them. Pediatric multiple sclerosis patients transitioning into adulthood f...
20
artículo
Publicado 2015
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The countries of the Andean subregion Bolivia, Chile, Colombia, Ecuador, Peru and Venezuela, integrated into the Andean Health Organization - Hipólito Unanue Convention (ORAS - CONHU) developed and approved by Resolution REMSAA XXXIII / 474 of 23 November 2012, Andean Policy Planning and Management of Human Resources in Health and implementation of its Action Plan 2013-2017.
