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1
artículo
Publicado 2021
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This research focused on the synthesis of a functional alginate-based material via chemical modification processes with two steps: oxidation and reductive amination. In previous alginate functionalization with a target molecule such as cysteine, the starting material was purified and characterized by UV-Vis,1 H-NMR and HSQC. Additionally, the application of FT-IR techniques during each step of alginate functionalization was very useful, since new bands and spiked signals around the pyranose ring (1200–1000 cm−1) and anomeric region (1000–750 cm−1) region were identified by a second derivative. Additionally, the presence of C1-H1 of β-D-mannuronic acid residue as well as C1-H1 of α-L-guluronic acid residue was observed in the FT-IR spectra, including a band at 858 cm−1 with characteristics of the N-H moiety from cysteine. The possibility of attaching cysteine molecules to an a...
2
tesis de maestría
Publicado 2017
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Tuberculosis is a leading killing disease worldwide with more than 9 million people a ected per year. Current diagnostic methods exhibit several disadvantages; one of the most promising alternatives to overcome this is the development of nanostructured diagnostic systems which are able to detect molecules associated with certain diseases. Graphene since its discovery has been the focus for the development of these sensing elements due to its excellent electronic properties. In this work, a graphene-based eld e ect transistor (FET) has been developed for tuberculosis DNA detection, in order to set the basis for a diagnostic method that overcomes current limitations. The sensing elements composed of graphene monolayers were manufactured in the stages of annealing of the substrate, addition of the linker and functionalization with the addition of a probe DNA for tuberculosis detection. Addi...
3
tesis de maestría
Publicado 2017
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Tuberculosis is a leading killing disease worldwide with more than 9 million people a ected per year. Current diagnostic methods exhibit several disadvantages; one of the most promising alternatives to overcome this is the development of nanostructured diagnostic systems which are able to detect molecules associated with certain diseases. Graphene since its discovery has been the focus for the development of these sensing elements due to its excellent electronic properties. In this work, a graphene-based eld e ect transistor (FET) has been developed for tuberculosis DNA detection, in order to set the basis for a diagnostic method that overcomes current limitations. The sensing elements composed of graphene monolayers were manufactured in the stages of annealing of the substrate, addition of the linker and functionalization with the addition of a probe DNA for tuberculosis detection. Addi...
4
artículo
Publicado 2024
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Transportation is the sector with the highest Greenhouse Gasses (GHG) emissions in Peru, and it is almost completely dependent on fossil energy resources. For the present analysis, we take into account carbon emissions during the production of electricity which may serve as a basis for understanding the carbon footprint (CF) of the alternatives that may be derived from the use of electrical vehicles. Based on the estimated values of emissions according to the type of electricity generation source (renewable or thermal), we have created scenarios to calculate emissions under the condition of electromobility. The CF of the combustion vehicle is 180 gCO2eq/pas-km, while the CF of electric vehicles with renewable energy, national electricity and fossil electricity are 12, 89 and 140 gCO2eq/pas-km respectively. The reduction of CO2 emissions eq. with renewable electrical energy is 93%, while ...
5
artículo
Publicado 2023
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Sensing drug substances by nanostructures are very important in accordance with the management of targeted drug delivery processes and drug substances detections. Boron nitride (BN), aluminum nitride (AlN), and gallium nitride (GaN) decorated carbon cage (BN-C, AlN-C, and GaN-C) scaffolds were assessed towards sensing the thiamazole (TMZ) drug through the wB97XD/6–31 + G* level of density functional theory (DFT) computations. The singular models were optimized and their combinations to each other were stabilized to obtain the interacting TMZ@Scaffold bimolecular complexes and their corresponding features. The results indicated the existence of non-covalent physical interactions between the substances and their electronic features indicated possibility of sensing function for the investigated scaffolds. Based on the variations of values of adsorption energy and energy gap, the features ...
6
objeto de conferencia
Publicado 2015
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A sensor based on molecularly imprinted polymers (MIP) was developed for determination of 3-(3,4-Dichlorophenyl)-1,1- dimethylurea (diuron). The MIP were synthesized by free radical polymerization in wich diuron acted as template, methacrylic acid (MAA) acted as functional monomer and ethylene glycol dimethacrylate (EGDMA) acted as crosslinker. For construction of the sensor, glassy carbon electrode was modified with Nafion® and MIP/NIP (non imprinted polymer) to see the contribution of MIP, as a film, in the diuron recognition. Differential Pulse Voltammetry was used to the quantification of diuron in a range of response 0.4 - 1.2 V in a PBS (pH=8). All parameters affecting the sensor were optimized. The sensor showed a linear response from 1.00x10-5 to 9.616x10-5 M in PBS 0.1 M (pH=8). The limit of detection was 0.58x10-5 mol L-1. The nanostructured sensor was prepared using carbon na...
7
artículo
Publicado 2021
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This project was supported by FONDECYT-BM (grant #0232019-FONDECYT-BM-IN.INV), FAPESP (grants #2019/006777 and #2014/50945-4), CNPq (grants #301728/2019-4, #408050/2018-7 and #465571/2014-0), and CAPES (PROJ. AUX/PE/PROEX N. 0674/2018). RL and GP received financial support from the OGI, Research Management Bureau (Project FC-F-6-2018).
8
artículo
Publicado 2021
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This work describes an electrochemical sensor for the selective recognition and quantification of amoxicillin and a β-lactam antibiotic in real samples. This sensor consists of a carbon paste electrode (CPE) modified with mag-MIP (magnetic molecularly imprinted polymer), which was prepared by precipitation method via free radical using acrylamide (AAm) as functional monomer, N,N′-methylenebisacrylamide (MBAA) as a crosslinker, and potassium persulfate (KPS) as initiator, to functionalized magnetic nanoparticles. The magnetic non-imprinted polymers (mag-NIP) were prepared using the same experimental procedure without analyte and used for the preparation of a CPE for comparative studies. The morphological, structural, and electrochemical characteristics of the nanostructured material were evaluated using Field emission gun scanning electron microscopy (FEG-SEM), Transmission electron mi...
9
tesis de grado
Publicado 2025
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Polyethylene terephthalate (PET) is a widely used material in container manufacturing, particularly in bottle production. It is characterized by its low cost and widespread availability. However, its improper disposal has significantly exacerbated global plastic pollution. For instance, less than 50% of plastic bottles are recycled. Moreover, studies indicate that this issue has led to a significant accumulation of plastic waste in the oceans, which continues to grow annually and could be considered floating islands of debris. This study proposes replacing PET with polylactic acid (PLA), a biodegradable and biocompatible polymer with suitable properties for bottle production. PLA also has a shorter decomposition time compared to PET, contributing to the reduction of carbon footprint and greenhouse gas emissions. The research methodology included a diagnostic phase to define objectives, i...
10
artículo
Analysis of functioning and role of Foster Groups in community mental health care. Lima, Peru, 2019.
Publicado 2022
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Objective: The operationalization and the role of a participatory model of diagnostic and therapeutic formulations called Foster Groups, implemented in a Community Mental Health Center in Lima, Peru, are analyzed. Material and Methods: The research was based on the participanting observation by experts in community mental health, public health, communication and social sciences, of a total of 24 Foster Group sessions held at the Nancy Reyes Community Mental Health Center in Chorrillos, Lima Peru, during the years 2018-2019. Results: The Foster Groups are structured in sequential phases that follow a logical process of diagnostic formulations and management plans, concurrently performed by professionals from different disciplines for a small group of users, thus allowing both, diagnoses as plans, to be more comprehensive. An environment of trust is generated, allowing people to share expe...
11
artículo
Publicado 2016
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In this work, it has been studied the influence of oxygenated functional groups on adsorption property of an activated carbon (CA), which was prepared from aguaje seeds (Mauritia flexuosa L. F.) by a chemical activation with phosphoric acid. Later the activated carbon was oxidized with nitric acid. The adsorptive capacity of phenolic compounds such as phenol, 4-chlorophenol and 4-nitrophenol were compared using both of the adsorbents, the activated carbon (CA) and the oxidized activated carbon (ACA). The characterizations of both activated carbons were analyzed by nitrogen adsorption measurements, Boehm titration, scanning electron microscopy (SEM) and FTIR spectroscopy. The oxidized sample (ACA) showed an increase in the microporous area from 756 m2/g to 1272 m2/g, likewise ACA presented an increase in the concentration of oxygenated functional groups from 4,22 mmolH+.g-1 to 4,82 mmolH+...
12
artículo
Publicado 2020
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High-surface-area carbon-based capacitors exhibit significant advantages relative to conventional graphite-based systems, such as high power density, low weight, and mechanical flexibility. In this work, novel porous carbon-based electrodes were obtained from commercial cotton fibers (CFs) impregnated with graphene oxide (GO) at different dipping times. A subsequent thermal treatment under inert atmosphere conditions enables the synthesis of electrodes based on reduced GO (RGO) supported on carbon fibers. Those synthetized with 15 min and 30 min of dipping time displayed high specific capacitance given their optimal micro-/ mesoporosity ratio. Particularly, the RGO/CCF15A supercapacitor reports a remarkable specific capacitance of 74.1 F g−1 at 0.2 A g−1 and a high cycling stability with a 97.7% capacitive retention, making this electrode a promising candidate for supercapacitor desi...
13
tesis de maestría
El objetivo de este trabajo es el desarrollo de un plan estratégico de la Fusión de Carbón Máster Bike-Shimano con base en el año 2021 para los próximos 5 años. Para formular este plan, analizamos los factores externos de ambas empresas a fin de conocer la situación del mercado actual y los factores internos para identificar las oportunidades que nos permitan atender las necesidades de dicho mercado. Tomando en cuenta que ambas empresas se destacan en I+D, utilizamos la metodología de Osterwalder con el objetivo de conocer las necesidades del cliente y, en base a ellas, establecer un modelo de negocio de constante evolución para la alianza. Como resultado de este trabajo, establecimos las estrategias de negocio, las cuales están desarrolladas en el plan funcional y el plan financiero. Estos planes reflejan un modelo de negocio sostenible basado en la innovación. El monto de i...
14
tesis de grado
El presente plan de negocios se encuentra en el rubro de comercialización de productos ecológicos, la empresa se dedicará a la elaboración y venta de carbón ecológico, elaborado a base de cáscara de coco, abastecida por los principales negocios dedicados a la venta de coco helado, quienes envían sus desperdicio al relleno sanitario. El aprovisionamiento de la materia prima se realizara en la ciudad de Tarapoto, ciudad conocida como la ciudad de las palmeras, por su alta producción de coco. En cuanto a la estructura organiza fue diseñada para una micro empresa, la que cuenta con funciones integradas para cada área. La empresa se acogerá al régimen laboral general. El plan económico y financiero ha determinado la rentabilidad del negocio, presenta el Valor actual neto económico (VAN) de S/. 238,020 y el Valor actual neto financiero de S/. 239,693. La Tasa interna de retorno ...
15
artículo
Publicado 2022
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This research aims to determine the effect of activated carbon obtained from cocoa husks (Theobroma cacao L.) on the adsorption of iron (II) present in water of an aquifer for human consumption. Charcoal was prepared at different carbonization temperatures (500, 600 and 700 °C) for 30 minutes and activated with phosphoric acid in the proportions of 1:1. Iron (II) adsorption was determined as a function of variations in mixing speed, contact time, charcoal dosage and stirring speed. It was determined that, over the range considered, agitation speeds had no significant effect on the percentage of iron (II) removal, being the dose of activated carbon and temperature, the most influential variables. The water samples had an initial iron concentration of 3.15 mg/L and 4 mg/L. The best iron (II) adsorption result was obtained with activated carbon at the carbonization temperature of 700 °C, ...
16
artículo
Publicado 2022
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Methylmercury (MeHg) is one of the most toxic organic mercury compounds found in the environment. The continuous exposure of human beings to this highly toxic compound may damage their nervous system. The present work reports the development and application of a novel electrochemical sensing technique for the quantification of MeHg using a modified carbon paste electrode with multi-walled carbon nanotubes (MWCNTs) combined with ion imprinted polymer, which is highly selective toward MeHg (CPE/MWCNTs/IIP-MeHg) detection. The ion imprinted polymer was synthesized using 2-mercaptobenzothiazole (MBT), acrylic acid (AA) and MeHg employed as ligand, functional monomer and template ion, respectively, and the synthesized material was characterized by Raman spectroscopy and SEM-EDX. Both the proposed and control sensors were characterized by cyclic voltammetry (CV) and electrochemical impedance s...
17
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
18
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
19
tesis de grado
Publicado 2018
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El uso de nanopartículas metálicas en sensores se da gracias a las propiedades características de estos materiales a escala nano, principalmente el aumento del área superficial. El área superficial disminuye cuando las nanopartículas se aglomeran, surgiendo la necesidad de soportarlas en sustratos de elevada área superficial. En este trabajo de investigación se estudia el método autoensamblado capa por capa para anclar nanopartículas de plata en diferentes superficies carbonosas: Carbones porosos jerarquizados, nanotubos de carbón con diferentes funcionalidades (Sin funcionalizar, funcionalizados con –COOH y –OH) y se evalúa el efecto sobre la detección de cianuro libre. Las nanopartículas de plata han sido sintetizadas utilizando dos agentes reductores diferentes (citrato de sodio y tirosina). La caracterización de las nanopartículas por voltamperometría cíclica en...
20
tesis de grado
Publicado 2015
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El objetivo del proyecto, es estimar la viabilidad técnica y económica a nivel de prefactibilidad para la instalación de una planta industrial de carbón activado a partir del bagazo de caña de azúcar (Saccharum Officinarum), en la región Loreto. El estudio de mercado estimó una demanda insatisfecha de 4 432, 279 toneladas de carbón activado para el año 2016, sobre la base de la demanda histórica de C.A. La ingeniería del proyecto, muestra el estudio de la materia prima, describe el proceso productivo, muestra los balances de materia y energía, especificaciones de los equipos, área necesaria requerida por el proyecto es de 10605.00 m2, incluyendo áreas verdes y el estudio de impacto ambiental. La organización del proyecto describe las áreas, secciones que comprende; funciones, responsabilidades y muestra el organigrama de la empresa. Se determinó que el proyecto requiere...
