Objetivo: Determinar cuáles son los factores de riesgo predictivos para la no efectividad de uso de Betalactámicos en pacientes hospitalizados por Infeccion del Tracto Urinario (ITU) en el servicio de medicina interna del Hospital Santa Rosa de Lima. Métodos: Estudio observacional, Analítico, de casos y controles, realizado en el Hospital Santa Rosa ; 280 pacientes hospitalizados con ITU, 140 casos y 140 controles, en el periodo enero-diciembre 2016 fueron incluidos, las variables a analizar fueron: Edad, Sexo, Diabetes Mellitus tipo 2, Enfeemedad Renal Cronica y hospitalizaciones previas. Resultados: Como resultado del análisis la variable Diabetes Mellitus 2 presento un OR: 7.79  IC 95% (4.57-13.27), Enfermedad renal crónica OR: 24.06 IC 95% (12.04- 48.07), Hospitalización previa OR: 3.93 IC 95% (2.37- 6.51) Siendo considerados como factores de asociación positivos y signi...

Introduction: Due to the presence of Covid-19 in the world, several countries, including Peru, have taken measures, including compulsory social isolation (quarantine). The inability of people to carry out their daily activities has directly affected their lifestyles. A population quite susceptible to these changes are university students. Objectives: To develop a validation scale to know what are the changes in lifestyles during the quarantine period in a population of university students from Lima, Peru. Results: The final scale was made up of 25 items. Bartlett's sphericity test was significant (3514.19, gl = 300, p <0.001) and the Kaiser-Meyer-Olkin sample size adequacy indicator was adequate (0.845). The four thematic areas were changes with respect to 1) Eating habits; 2) Harmful habits; 3) Physical activity; and 4) Use of communication media. As it was a Likert-type ordinal meas...

Introduction: Metabolic syndrome (MetS) is a group of cardiovascular risk factors characterized by the presence of low-grade chronic inflammation. Among all the inflammatory biomarkers associated with MetS, the best characterized and well standardized is C-Reactive protein (CRP). Objectives: To evaluate the association between C-Reactive protein and metabolic syndrome in the Peruvian population of the PERU MIGRANT study. Methods: Secondary database analysis of the PERU MIGRANT study. MetS was considered according to the Harmonizing the Metabolic Syndrome criteria. For CRP, a cutoff point of ≥ 3 mg/L was established. Results: We worked with a total of 958 subjects. The prevalence of MetS was 24.53%. In the simple regression analysis, it was found that people with high CRP levels had a 75% higher frequency of having MetS, compared to those who did not p...

Objective: To evaluate the validity of the risk test of the American Diabetes Association (ADA Test) as a screening for hyperglycemia in a sample of workers in Lima, Peru. Methods: Cross-sectional study of diagnostic tests. Secondary analysis of the data generated by the electronic health record of an occupational polyclinic, carried out in January and February 2020. The sample was made up of workers from different areas who attended for their occupational medical evaluation. Prediabetes was considered with a fasting glucose ≥ 100 mg / dl but less than 126 mg / dl. Results: 397 subjects were evaluated. The prevalence of hyperglycemia was 29% (115/397). With a cutoff ≥ 3 points, the ADA Test presented an area under the curve of 0.868, a sensitivity of 94.8%, and a specificity of 51.8%. The PPV was 44.5% and the NPV was 96.1%. Finally, the positive likelihood c...

Objetivo: Evaluar el perfil de sueño en una muestra de estudiantes universitarios durante el tiempo de cuarentena en Lima, Perú. Métodos: Estudio transversal analítico realizado a través de una encuesta virtual durante el período de aislamiento social en el Perú, consecuencia de la pandemia por el COVID-19. Se utilizó el Cuestionario Oviedo de Calidad de Sueño (COCS). Resultados: Como resultados principales se encontró que según las variables sociodemográficas: sexo, zona de residencia, carrera profesional, ciclo académico, mostraron cambios respecto al sueño. Respecto al análisis comparativo del COCS en la dimensión satisfacción subjetiva, insomnio e hipersomnia no existen diferencias significativas en todas las variables sociodemográficas con excepción de la variable cambio (p < 0.05).

Objetivo: Evaluar la validez de la prueba de riesgo de la Asociación Americana de Diabetes (Prueba ADA) como cribado para prediabetes en una muestra de trabajadores peruanos. Métodos: Estudio transversal de pruebas diagnósticas. Análisis secundario de los datos generados por el registro electrónico en salud de un policlínico ocupacional. La muestra estuvo conformada por trabajadores de diferentes áreas que asistieron para su evaluación médica ocupacional. La muestra estuvo conformada por trabajadores de diferentes áreas que asistieron para su evaluación médica ocupacional. Se consideró prediabetes con una glucosa en ayunas ≥ 100 mg/dl pero menor a 126 mg/dl. Resultados: Se evaluaron 397 sujetos. La prevalencia de prediabetes fue 29% (115/397). Con un corte ≥ 3 puntos, la Prueba ADA presentó un área bajo la curva de 0.868, una sensibilidad del 94,8% y una especificidad ...

Objetivo: Determinar cuáles son los factores de riesgo predictivos para la no efectividad de uso de Betalactámicos en pacientes hospitalizados por Infeccion del Tracto Urinario (ITU) en el servicio de medicina interna del Hospital Santa Rosa de Lima. Métodos: Estudio observacional, Analítico, de casos y controles, realizado en el Hospital Santa Rosa ; 280 pacientes hospitalizados con ITU, 140 casos y 140 controles, en el periodo enero-diciembre 2016 fueron incluidos, las variables a analizar fueron: Edad, Sexo, Diabetes Mellitus tipo 2, Enfeemedad Renal Cronica y hospitalizaciones previas. Resultados: Como resultado del análisis la variable Diabetes Mellitus 2 presento un OR: 7.79  IC 95% (4.57-13.27), Enfermedad renal crónica OR: 24.06 IC 95% (12.04- 48.07), Hospitalización previa OR: 3.93 IC 95% (2.37- 6.51) Siendo considerados como factores de asociación positivos y signi...

Introduction: Due to the presence of Covid-19 in the world, several countries, including Peru, have taken measures, including compulsory social isolation (quarantine). The inability of people to carry out their daily activities has directly affected their lifestyles. A population quite susceptible to these changes are university students. Objectives: To develop a validation scale to know what are the changes in lifestyles during the quarantine period in a population of university students from Lima, Peru. Results: The final scale was made up of 25 items. Bartlett's sphericity test was significant (3514.19, gl = 300, p <0.001) and the Kaiser-Meyer-Olkin sample size adequacy indicator was adequate (0.845). The four thematic areas were changes with respect to 1) Eating habits; 2) Harmful habits; 3) Physical activity; and 4) Use of communication media. As it was a Likert-type ordinal meas...

Introduction: Metabolic syndrome (MetS) is a group of cardiovascular risk factors characterized by the presence of low-grade chronic inflammation. Among all the inflammatory biomarkers associated with MetS, the best characterized and well standardized is C-Reactive protein (CRP). Objectives: To evaluate the association between C-Reactive protein and metabolic syndrome in the Peruvian population of the PERU MIGRANT study. Methods: Secondary database analysis of the PERU MIGRANT study. MetS was considered according to the Harmonizing the Metabolic Syndrome criteria. For CRP, a cutoff point of ≥ 3 mg/L was established. Results: We worked with a total of 958 subjects. The prevalence of MetS was 24.53%. In the simple regression analysis, it was found that people with high CRP levels had a 75% higher frequency of having MetS, compared to those who did not p...

“Background: The metabolically obese normal-weight (MONW) phenotype has been considered a risk factor for different chronic diseases, but its role in high blood pressure (HBP) is still unclear. The aim of the study is to determine if the MONW phenotype constitutes a risk factor for hypertension in Peruvian adults belonging to a 5-year cohort. Methods: This is a retrospective cohort study. A secondary analysis from the database of the PERU MIGRANT study was carried out from the MONW and non-MONW cohorts; after a 5-year follow-up, the appearance of HBP was evaluated in the subjects of both cohorts. To assess the strength and magnitude of the association, a Poisson regression model (crude and adjusted) with robust variance was used. The measure of association was the relative risk (RR). Results: The incidence of HBP was 11.30%. In the multivariable analysis, subjects with the MONW phenoty...

Introducción: Aunque se está generando múltiple evidencia clínica sobre la COVID-19, también es crítico abordar sobre las estrategias y acciones que han adoptado las personas para enfrentar situaciones estresantes durante la cuarentena obligatoria debido a la pandemia. Objetivo: Determinar los factores asociados al afrontamiento psicológico frente a la COVID-19 en la población general. Métodos: Estudio transversal analítico. Se reclutaron los participantes a través de una encuesta en línea, durante el periodo de pandemia por la COVID-19. Se evaluó el nivel de afrontamiento pasivo y activo, utilizando la escala de afrontamiento frente a riesgos extremos. Adicionalmente, se utilizó la media de los puntajes de afrontamiento pasivo y activo, se evaluó la asociación con variables sociodemográficas, pertenencia a grupos, cumplimiento de aislamiento social y reporte de conocer ...

Introduction: Piura, located in a seismic zone, faces challenges related to food security. The aim of this study was to analyze aspects related to food insecurity in the region following the 6.1-magnitude earthquake that occurred in 2021, within the context of the COVID-19 pandemic. Methods: A secondary analysis was performed in 177 people exposed to the earthquake in Piura. Food insecurity was assessed with the Household Food Insecurity Access Scale. Its association with insomnia, resilience, anxiety/depressive symptoms, and general variables were determined using generalized linear models. Results: Food insecurity was observed in 31.1% (95% CI: 24.3–38.4) of participants. This prevalence was higher in people with mild (PR: 1.73, 95% CI: 1.12–2.70) and moderate (PR: 1.55, 95% CI: 1.09–2.22) anxiety symptoms, severe depressive symptoms (PR: 2.74, 95% CI: 1.24–6.03), and previous ...

Objectives To determine the association between internet addiction disorder (IAD) and anxiety and depressive symptomatology in high school students in two private schools in Chiclayo, Peru, during the COVID-19 pandemic. Materials and methods Analytical cross-sectional investigation of 505 adolescents from two private schools. The dependent variables were anxiety and depressive symptomatology, measured with the Beck Adapted Depression Questionnaire (BDI-IIA) and the Beck Anxiety Inventory (BAI), respectively. The main independent variable was IAD, measured with the Internet Addiction Test instrument(IATI). Prevalence ratios (PR) and 95% confdence intervals (95%CI) were estimated. Results The average age was 14.16 years and 54.9% were women. 22.2% and 3.2% presented mild and moderate IAD; respectively. 9.3% presented severe anxiety and 34.3% severe depressive symptomatology. In the simple ...

Objective: We aimed to evaluate the association between sleep quality and erectile dysfunction in young university students. Methods: A cross-sectional survey was conducted in men aged 18–30 years from Universidad Ricardo Palma, Lima, Peru. The survey comprised the International Index of Erectile Function, Pittsburgh Sleep Quality Index, Berlin questionnaire, and questions related to sociodemographic data. Prevalence ratios were estimated with generalized linear models. Results: Of 381 participants, the median age was 23 years. Half of the students (50.9%) had poor sleep quality, of which 72.7% had mild erectile dysfunction and 20.6% mild to moderate dysfunction. Prevalence of erectile dysfunction was significantly higher in students with poor sleep quality than in students with good sleep quality (aPR = 6.48; 95% CI: 4.58–9.17) after adjusting for age, academic year, nutritional sta...

Background: Obesity causes the loss of body homeostasis and pre-disposes to the development of disease; some individuals present al-terations described even having a normal body mass index (BMI), and these are called thin metabolically obese. The objective was to carry out a systematic review with meta-analysis to determine the preva-lence of metabolically-obese normal-weight (MONW) worldwide.Methods: The search for studies was conducted from May to June 2022 in the EMBASE, PubMed, WOS, and Scopus databases. The pu-rification and ordering of data were carried out using the Excel 2016 program, later a meta-analysis with the Stata version 17 program.Results: A total of 408,251 people with normal BMI were identi-fied, of whom 78,054 had a metabolic disorder, and the prevalence after the meta-analysis was 26.78% (95% confidence interval: 18.45 - 36.03) with high heterogeneity (I2 = 99.86%).C...

During the COVID-19 pandemic, university students have adopted measures that completely transformed their educational environment, and this has generated an increase in psychological stress. The present study aimed to identify the factors associated with anxiety, depression, and stress in students at a university in Peru during the COVID-19 pandemic in 2020. We conducted a cross-sectional analytical study in students in Lima, Peru. The DASS-21 scale was used to measure levels of depression, anxiety, and stress and associate it with socio-educational and COVID-19-related variables using generalized linear models with Poisson distribution, log link, and robust variance. Of 400 students surveyed, 19.2%, 23.2% and 17.2% of students presented depression, anxiety, and stress, respectively. The frequency of depression (PR = 0.91, 95%CI: 0.84–0.99), anxiety (PR = 0.90, 95%CI: 0.83–0.99) and ...

Introducción: El síndrome metabólico (MetS) es un grupo de factores de riesgo cardiovascular que se caracteriza por la presencia de inflamación crónica de bajo grado. Entre todos los biomarcadores inflamatorios asociados al MetS, el mejor caracterizado y bien estandarizado es la proteína C-Reactiva (PCR). Objetivo: Evaluar la asociación entre la proteína C-Reactiva y el síndrome metabólico en la población peruana del estudio PERU MIGRANT. Métodos: Estudio transversal analítico. Análisis de base de datos secundario del estudio PERU MIGRANT. Se consideró MetS según los criterios de Harmonizing the Metabolic Syndrome. Para la PCR, se dispuso un punto de corte ≥ 3 mg/L. Se usó modelos lineales generalizados de familia de Poisson para hallar la razón de prevalencias cruda y ajustada. Resultados: Se trabajó con un total de 958 sujetos. La prevalencia de MetS fue de 24,53%....

Introducción: Los estudiantes universitarios se han visto obligados a cambiar sus hábitos debido a la cuarentena por la pandemia COVID-19. Objetivo: Desarrollar una escala de validación para conocer los cambios en los estilos de vida durante la cuarentena en estudiantes universitarios de Lima, Perú. Métodos: Estudio transversal, observacional, analítico. Se encuestaron a 549 universitarios de medicina humana y psicología de dos universidades privadas de Lima de forma virtual. Se realizó la validez de constructo, la fiabilidad y los rangos/categorías para calificar el estilo de vida. Resultados: La escala final quedó conformada por 25 reactivos. La prueba de esfericidad de Bartlett fue significativa (3514,19, gl= 300, p<0,001) y el indicador de adecuación del tamaño de muestra Kaiser-Meyer-Olkin fue adecuado (0,845). Las cuatro áreas temáticas fueron cambios con respecto a 1...

Introducción: La resistencia a la insulina (RI) es una de las principales causas del desarrollo de patologías crónicas. Es indispensable su detección temprana, por ello es importante estudiar métodos más asequibles y menos costosos como los biomarcadores. Objetivo: Determinar la precisión diagnóstica de once biomarcadores para RI en una muestra de pobladores peruanos. Metodología: Estudio de pruebas diagnósticas. Análisis de base de datos secundario del estudio PERU MIGRANT. Para medir RI se utilizó como referencia la evaluación del modelo homeostático (HOMA-IR) ≥ 2,8. Los biomarcadores se basaron en la ratio de lípidos, los indicadores de lípido visceral, los indicadores con triglicéridos y glucosa (TyG), y los indicadores con cintura abdominal. Para la precisión se utilizó el análisis de la curva de características operativas del receptor y el área bajo la curva...

Introduction: Piura, located in a seismic zone, faces challenges related to food security. The aim of this study was to analyze aspects related to food insecurity in the region following the 6.1-magnitude earthquake that occurred in 2021, within the context of the COVID-19 pandemic. Methods: A secondary analysis was performed in 177 people exposed to the earthquake in Piura. Food insecurity was assessed with the Household Food Insecurity Access Scale. Its association with insomnia, resilience, anxiety/depressive symptoms, and general variables were determined using generalized linear models. Results: Food insecurity was observed in 31.1% (95% CI: 24.3–38.4) of participants. This prevalence was higher in people with mild (PR: 1.73, 95% CI: 1.12–2.70) and moderate (PR: 1.55, 95% CI: 1.09–2.22) anxiety symptoms, severe depressive symptoms (PR: 2.74, 95% CI: 1.24–6.03), and previous ...