El jengibre peruano, considerado un superfood, es un producto potencial agroexportador del país dada su importancia en el consumo a nivel mundial por sus propiedades funcionales y la tendencia hacia alimentos que proporcionen beneficios a la salud, factores que se incrementaron especialmente en tiempos de la pandemia COVID-19. El Perú actualmente es el cuarto exportador más importante detrás de China, India y Tailandia, siendo nuestros fuertes competidores a nivel mundial, al igual que Brasil en América Latina. La presente investigación identifica y analiza los factores que forman parte del comportamiento de oferta y demanda y su influencia en la competitividad de las exportaciones del jengibre peruano en el periodo de 2012-2021, evaluando cuál es su nivel de incidencia y cómo influye en los diferentes mercados de destino. Para tal efecto, se calculó el Índice de Ventajas Compa...

El presente trabajo se realizó con el objetivo de conocer la importancia de la comunicación dentro de la gestión de la relación con los grupos de interés. Actualmente, las organizaciones buscan articular sus acciones con los problemas que presenta la sociedad, primordialmente con los retos de sostenibilidad. Para que estas acciones sean efectivas, se debe analizar y reconocer quienes son aquellos grupos de interés que se ven afectados por la empresa. De esta manera, el plan de trabajo y el modelo de negocio trabajarán de la mano con aquellos involucrados y comprometidos en la mejora social, económica y medio ambiental. Este estudio presenta la evolución de la responsabilidad social y como esta ha pasado de ser un concepto aplicado a una sola área de la empresa a trabajarse de manera transversal como un modelo de gestión.

The present case corresponds to a 1-month-old male patient with a diagnosis of non-compacted cardiomyopathy associated with congenital heart defects. Noncompacted cardiomyopathy is newly included by the AHA as its own since the second half of the last decade. The diagnosis is mainly echocardiographic. Symptoms in children under one year may start with heart failure. The evolution is variable and tends to improve in some cases. Finally, in later decades, heart failure, thromboembolic events, malignant arrhythmias and sudden death become more pronounced. The management is in medicines for heart failure, to avoid malignant arrhythmias and thromboembolic events.

El presente caso corresponde a un paciente de 1 mes de vida, sexo masculino con diagnóstico de miocardiopatía no compactada asociada a defectos cardiacos congénitos. La miocardiopatía no compactada recién es incluida por la AHA como entidad propia a partir de la segunda mitad de la década pasada. El diagnóstico principalmente es ecocardiográfico. La sintomatología en menores de un año puede empezar con falla cardiaca. La evolución es variable con tendencia a la mejoría en algunos casos para finalmente en décadas posteriores se hace más pronunciada la falla cardiaca, eventos tromboembólicos, arritmias malignas y muerte súbita. El manejo esta en medicamentos para falla cardiaca, evitar arritmias malignas y eventos tromboembólicos.

Introduction: The presence of calcifications may be useful for the diagnosis of breast neoplasia. Objective: To determine the association between the characteristics of mammographic calcifications and malignant neoplasia. Methods: Observational, analytical, retrospective of cases and controls. Developed in the Gynecology Breast Pathology Unit. Female patients with mammogram suggestive of malignant neoplasm with a positive malignancy biopsy were included as cases, and 67 patients without histological evidence of malignancy as controls. Results: The average age of the cases was 54.12 years, in the controls 50.34. 50,.9% (59) are older than or equal to 50 years, OR 2,399 95% CI (1,125-5,114) p = 0.022, of these 52.5% (31) had breast cancer. 9.5% (11) had calcifications suspicious of malignancy, the most frequent, the amorphous and the pleomorphic fine. 37.1% (43) of the total cases have the...

Introducción: La presencia de calcificaciones puede ser útil para el diagnóstico de neoplasia de mama. Objetivo: Determinar la asociación entre las características de las calcificaciones mamográficas y neoplasia maligna. Métodos: Estudio observacional, analítico, retrospectivo de casos y controles. Desarrollado en la Unidad de Patología Mamaria de ginecología. Se incluyeron como casos a pacientes mujeres con mamografía sugerente de neoplasia maligna con biopsia positiva a malignidad y como controles a 67 pacientes sin evidencia histológica de neoplasia. Resultados: La edad media de los casos fue de 54,12 años, en los controles 50,34. El 50,9%(59) son mayores o iguales a 50 años, OR 2,399 IC 95% (1,125 – 5,114) p=0,022, de estos el 52,5% (31) tenían cáncer de mama. El 9,5%(11) presentaron calcificaciones sospechosas de malignidad, las más frecuentes, la amorfa y la fina...

duplicación 4q,We report the case of a newborn with multiple congenital malformations by unbalanced chromosome complement 46,XY,der(20),t(4;20)(q21;q13.1)mat originated by a reciprocal translocation apparently balanced between chromosomes 4 and 20 in the mother who had a karyotype 46,XX,t(4;20)(q21;q13.1) de novo. The proband´s karyotype showed a duplication of the distal segment of the long arm of chromosome 4 (partial trisomy 4q). The phenotype was altered, presenting several craniofacial, and malformations of internal organs that led to his early death. hereditary commitment and to detect posible carriers. The risks also were determined to provide an appropiate genetic counseling.

Medical genetics is rapidly advancing thanks to technologies that accurately define which genes are involved in the development of diseases. Some syndromes occur in the general population, and their diagnosis and treatment are important to provide patients with an adequate care and prognosis. We present the case of a dysmorphic child who was born at 33 weeks of pregnancy by caesarean delivery due to preeclampsia. Cytogenetic analysis showed a heterozygous deletion on the short arm of chromosome 17 (46, XX, del 17p11.2). The diagnosis was complemented by MLPA analysis, which measures the presence/absence of certain genes defined in some syndromes, and confirmed the deletion of 2.1 megabases of DNA, including the RAI1 gene, responsible for the Smith-Magenis syndrome.

The partial trisomy 4p, usually originated from translocations between chromosome 4 and other non-homologous chromosomes or pericentric inversion of chromosome 4, causing abnormal chromosome gametes between normal and the inverted one, yielding a recombinant chromosome duplication can carry small ami segments (4p) or the long arm (4q) the latter being non-viable. The phenotypic characteristics of this condition present with severe mental retardation, delayed psychomotor development, craniofacial anomalies, strabismus, musculoskeletal defects, heart defects, cryptorchidism and micropenis. We describe the case of a 1-year 6-month child with delay in psychomotor development and dysmorphic features, having a recombinant 4p duplication of paternal origin. It is the first case of duplication 4p found in our institution due to hereditary, it is necessary to perform counseling to parents and mon...

Chromosomal deletions are structural abnormalities that cause loss of genomic material, depending on itslength they use to generate several disabling genetic conditions. Interstitial deletion of chromosome 17 shortarm in 17p11.2 region is related to the appearance of phenotypic characteristics related to a genetic conditionknown as Smith-Magenis syndrome. This deletions spans in a range between <1.5 and 9 Mb, shows somefeatures as craniofacial dysmorphia, delayed psychomotor development, speech problems, sleep disorders,limb abnormalities, malformations of brain, heart and kidney also are expressed. We present a case of a 10monthsold girl with brachycephaly, bulging forehead, sunken eyes, epicanthal folds, malformed ears, shortphiltrum, small mouth and ventriculomegaly. The gir´sl karyotype was 46,XX,del(17)(p11.2), no moleculartests were performed because they were not available, bu...

We describe the case of a male term neonate with psychomotor development anomalies, craniofacial defects, limbs and genital anomalies, born at Instituto Nacional Materno Perinatal in which an interstitial chromosomal deletion was found in the long arm of chromosome 4. The karyotype of the newborn was 46, XY, del (4) (q22q25) de novo. The phenotypic traits observed in the propositus were compatible with 4q- syndrome.

Trisomy 8 is an uncommon anomaly in neonates, frequently being a lethal condition among individuals with pure trisomiclines and more tolerable in mosaics cases. This aneuploidy is mainly characterized by a moderate - severe intellectual deficitand poor motor coordination. Affected individuals presents craniofacial malformations, prominent forehead, arched palate,deformed ears with low implantation, elongated trunk, reduced motility, articular defects and deep plantar grooves, which isone of the main characteristics of this condition. Abnormalities of internal organs are of varying severity. We present the reportof two cases of trisomy 8 or Warkany syndrome 2 born at Instituto Nacional Materno Perinatal.