OBJECTIVE: To describe the experience with ivermectin and thiabendazole in patients attended at the Tropical Medicine Institute “Daniel A. Carrión”- UNMSM. MATERIAL AND METHODS: During 2001 and 2002, ivermectin (0,2 mg/kg in single dosis) and thiabendazole (25 mg/kg/3days) were administered to 22 (Group 1) and 20 (Group 2) patients with diagnosis of Strongyloides stercoralis in stools. Controls were performed between 20 and 40 days following treatment. RESULTS: Mean age was 21,8 years (SD 22,6) for group 1 and 33,5 years (SD 14,2) for group 2. There were 12 males (54,5%) in group 1 and 7 (35%) in group 2. Ivermectin was 100% efficient while thiabendazole was 95%; only one case needed a second cycle because of high amount of parasites from the beginning; his next control was negative. Most frequent symptoms were diarrhea (71,4%), abdominal pain (61,9%) and epigastric pain (47,6%); al...

Objective: To conduct metaanalysis by reviewing bibliographic references published during the last 20 years that directly or indirectly compared serologic and parasitologic diagnostic methods for Strongyloides stercoralis infection. Material and methods: We tried to build a tetracoric table to obtain values of serology sensitivity and specificity, choosing parasitologic methods as gold standard. Finally, those references that compared ELISA with parasitologic methods were selected and information was obtained to calculate positive and negative predictive values. Results: Twenty-five references were chosen by applying selection criteria. Positive and negative predictive values were 85,33% and 97,83%, respectively. Conclusion: These results show the potential usefulness of ELISA method as a screening test for strongyloidiasis, in order to facilitate studies in populations exposed to this p...

Objective: To standardize ELISA technique for human Strongyloides stercoralis infection diagnosis. Material and methods: A crude antigen was prepared using filariform larvae obtained from positive stool samples cultured with charcoal. Harvested larvae were crushed by sonication and washed by centrifugation in order to obtain protein extracts to be used as antigen. Final protein concentration was 600 µg/mL. Several kinds of ELISA plates were tested and antigen concentration, sera dilution, conjugate dilution and cut off were determined to identify infection. Sera from patients with both hyperinfection syndrome and intestinal infection demonstrated by parasitological examination were positive controls and sera from people living in non-endemic areas with no infection demonstrated by parasitological examination were negative controls. Results: Best values were 5 µg/mL for antigen, 1/64 fo...

La presente tesis trata sobre el diseño óptimo y la construcción de un tipo de transformadores de corriente para medición y/o protección eléctrica en media tensión (10 KV), compactos, de acuerdo a la época, moldeados en resina y con la capacidad de soportar altos esfuerzos de cortocircuito en condiciones de falla y que sean por consiguiente de gran confiabilidad. El presente tema está dividido en cuatro capítulos antecedidos de una introducción al tema; finalmente se acompañan importantes observaciones y conclusiones luego se indica la bibliografía seguida del apéndice. El estudio de loa transformadores de corriente está basado en las técnicas del circuito equivalente del transformador. Para determinar la corriente de excitación se ha tenido que utilizar las curvas características de pérdidas en el fierro y excitación en corriente alterna para bajo niveles de inducci�...

The objective was to determine how remote education is related to the academic satisfaction of FCCSS UNFV 2020-1 students. The research was basic, with a descriptive scope or level and a non-experimental design. There was a population of 503 students with regular enrollment and attendance from the three schools of the Faculty of Communication Sciences. After applying probabilistic sampling there were 132 students. The results indicated that the students are not very satisfied with the dimensions: Subjects (21.3 %), Teaching 11.3 % and Contents of the syllabus (26.8 %), but with the dimensions communication and platform or virtual environment, satisfaction is average (43 %). It is concluded that a platform based on open software adapted to the reality of the FCCSS-UNFV is necessary, training for students and teachers in the use of new technologies and virtual environments. Acquire new equ...

En un mundo post pandémico, resulta cada vez más difícil, convencer y retener a un público usuario altamente informado. Un consumidor globalizado, resiliente y consciente de conceptos como la ecoeficiencia y la economía circular. Por otro lado, existe una adaptación a la omnicanalidad para acceder a productor y servicios, la flexibilidad de horarios de atención y los diferentes aplicativos para realizar pagos y configurar pedidos para entrega a domicilio, que hoy en día, han abierto las puertas a nuevos mercados, pero, también han orientado a la humanidad hacia una alfabetización digital obligatoria. Un desafío para los nuevos profesionales que egresan de especialidades como publicidad y marketing que, tienen como reto desarrollar competencias digitales y a la vez, habilidades blandas. En este artículo se describen resultados de un estudio realizado en una institución educat...

El objetivo: Describir cómo influye la Programación Neurolingüística (PNL), en la persuasión publicitaria de los maestrandos de marketing UNFV 2019. Conocer cómo se desenvuelven cuando tienen que convencer a sus clientes, usando sus convicciones y sobre todo sus conocimientos de las técnicas neurolingüísticas. Método: Investigación descriptiva explicativa, diseño no experimental, transaccional. Con una población 44 maestrandos de marketing y negocios de la EUPG-UNFV. Se uso una adaptación del Test estilo autoaprendizaje con Modelo PNL. Resultados: La programación neurolingüística nos ayuda a comprender patrones y conductas de las personas que son clientes de los profesionales marketeros, quienes pueden usar esta ciencia entendiendo los mecanismos mentales que se generan sus clientes ante una necesidad, por lo tanto, una vez identificados, pueden llegar a ser trabajados e...

Con el propósito de genotipificar las mutaciones de resistencia a antiretrovirales existentes en una porción de la Trancriptasa Reversa (TR) del Virus de la Inmunodeficiencia Humana 1 Subtipo B (codones 151 a 261), se colectaron once muestras (n=11) provenientes del Comité de Prevención y Control de SIDA (COPRECOS) del Hospital Militar Central como parte del proyecto: “Detección de Mutaciones Puntuales en VIH-1 relacionadas a Resistencia a Antiretrovirales”. Todas las muestras se sometieron a amplificación por PCR y secuenciamiento mediante el método de Sanger para proceder al análisis de las mutaciones con el Software HIV db versión 4.1.2 de la Universidad de Stanford (disponible online). De acuerdo a los resultados de genotipificiación de la secuencia parcial de la TR, sólo dos de las 11 muestras presentaron mutaciones primarias relacionadas a resistencia a antiretrovira...

The objective was to determine how remote education is related to the academic satisfaction of FCCSS UNFV 2020-1 students. The research was basic, with a descriptive scope or level and a non-experimental design. There was a population of 503 students with regular enrollment and attendance from the three schools of the Faculty of Communication Sciences. After applying probabilistic sampling there were 132 students. The results indicated that the students are not very satisfied with the dimensions: Subjects (21.3 %), Teaching 11.3 % and Contents of the syllabus (26.8 %), but with the dimensions communication and platform or virtual environment, satisfaction is average (43 %). It is concluded that a platform based on open software adapted to the reality of the FCCSS-UNFV is necessary, training for students and teachers in the use of new technologies and virtual environments. Acquire new equ...

Con el fin de que los transformadores de potencia tengan un normal funcionamiento, la norma ASTM D-1816 indica que el contenido de agua presente en el aceite de los transformadores deberán sean iguales o inferiores a 30 ppm. Cuando estos valores sobrepasan estos valores, nos indica que la parte activa del transformador presenta un alto contenido de agua que pueden poner en riesgo el normal desempeño del transformador incluso a fallar y salir de servicio. La forma tradicional de reparar estos transformadores es realizar el proceso de secado en un taller de reparaciones. Este proceso por lo general tiene una duración aproximada de 28 días desde el desmontaje del transformador, hasta su instalación y puesta en marcha en el cliente.

La educación es un fenómeno social y cultural que va evolucionando al ritmo de la humanidad, este proceso se ajusta y se adapta a las necesidades y las exigencias del contexto digital; sin embargo, en los últimos años son los individuos los que están cambiando las formas de aprender y percibir la realidad con competencias digitales relacionadas al desarrollo de la enseñanza con el uso de aplicaciones web. La investigación busca como objetivo principal, determinar el nivel de incidencia entre las competencias digitales y el uso de herramientas web 3.0 en una universidad pública en Lima. Para ello se tomó una muestra de 132 universitarios pertenecientes de la escuela profesional de Ciencias de la Comunicación, en adelante denominada EPCCOM. La metodología fue basada en un enfoque cuantitativo y utilizando la prueba estadística de Chi cuadrado. La investigación concluye, demost...

Objective: To determine the presence of Acanthamoeba genus in symptomatic persons. Setting: Cayetano Heredia National Hospital Ophthalmology Service. Material and methods: One hundred individuals without evidence of corneal lesion had corneal samples examined during April and May 1999. Samples were sowed in neapolitan agar and non-nutritive agar, incubated and checked after 7 days. Results: Acanthamoeba cysts were found in 16 out of the 100 samples; 44 subjects were male; diagnosis was not different in both sexes; 63% of individuals were below 20 year-old; infection was predominant in younger people; 89% referred visits to areas where the parasite had been reported (Piura, Ica); 58 subjects referred swimming in pools or rivers. Out of 76 subjects who reported daily use water source, 63% obtained it from water-tank cars and 25% from wells; infection was more frequent in the latter ones (3...

Objective: To estimate seroprevalence of human toxocariosis in Lima inhabitants. Design: Cross-sectional study, non aleatory selection. Material and methods: To people living in Lima city urban marginal communities, an interview and clinical examination were done and serum samples obtained to detect antibodies against Toxocara by ELISA technique. Stool samples were also obtained to check parasites causing cross reactions with serology. Results: From 553 persons examined 23,3% were reactive. There were no sex differences and ELISA results related to anemia, leucocytosis, eosinophilia or intestinal parasites. People older than 15 yearold had twice the possibility to be reactive. Most frequent symptom in positive individuals was decrease of visual capacity. Most frequent parasites were Blastocystis hominis, Entamoeba coli, Giardia lamblia. Conclusions: Human toxocariosis is frequent in Lima...

Objective: To determine human toxocariosis prevalence in subjects presenting suspicious ocular symptoms. Material and methods: Subjects with symptoms and suspicion of intraocular toxocariosis damage attended at various Lima hospitals ophtalmology services were studied. Blood samples were obtained and Toxocara serology by ELISA technique was done, along with leukocyte counts. An epidemiological questionnaire was also applied to identify behaviors associated to infection risk. Results: Forty-five persons were studied, 19 male and 26 female, 55,6% were reactive by ELISA test. No differences in sex and serology results were observed; among participants between 15 and 45 years old, 63% were reactive. There were no significant differences in the epidemiological factors studied. No association between eosinophilia and serology was observed. Conclusions: Human infection by Toxocara is frequent i...

OBJECTIVE: To determine the presence of Acanthamoeba genus in several Ica city (south of Lima) water sources. MATERIAL AND METHODS: Thirty-one samples from 7 natural water sources (lagoons) and 24 artificial sources (wells, tanks for rehabilitation therapy, reservoirs and cisterns) were examined during May 1997 in several points of the city. Samples were sowed in Agar Myast and in Agar Napolitan, incubated at 37°C and checked after 10 days. Positive samples were inoculated to immunocompetent mice by intranasal route; resultant lesions were cultured again following the same procedure. RESULTS: In 11 samples (35,5%) Acanthamoeba cysts were isolated, 6 from natural sources and 5 from artificial sources; among negative samples only one came from natural source and the other 19 came from artificial sources inside homes or from the local hospital. OR =22,8 was obtained for exposition to natur...

Objetive: To standardise ELISA technique for Toxocara canis human infection diagnosis by using excreted-secreted antigen prepared in our country. Material and methods: T. canis eggs were collected by incubation with formalin (2%) at 28oC in order to obtain third stage larvae that were freed and incubated in RPMI at 37°C for 7 days; the medium was replaced by a similar one and stored at - 20°C. Antigen was concentrated and protein dosage was made. Sera from patients with toxocariasis and newborns were used as positive and negative controls by ELISA technique, dilutions ¼ to 1/1024. Polystyrene plates were sensitised with antigen in several concentrations and conjugated peroxidase with horseradish IgG, anti human IgG and substrate OPD were used. Absorbance was read with spectrophotometer (Multiskan plus labsystems) at 492 nm. Cut off point was determined by negative sera absorbencies ar...

Objective: To estimate intestinal coccidiae infection prevalence of in asymptomatic children from a marginal community in Lima. Material and Methods: Stool samples were collected from 79 asymptomatic children aged 7 months through 7 year-old from Asentamiento Humano “Las Casuarinas de Villa”. Direct smear and colored frotis by Kinyoun technique were prepared. Another portion was placed in small bottles with potasium bicromatum 2,5% to obtain sporulation. After 10 days, frotis were colored by Kinyoun. Results: Direct smear detected one sample with Cryptosporidium (1,3%). In frotis colored before sporulation, 3 with Cryptosporidium (3,8%) were found and one with Isospora belli (1,3%); in frotis colored post-sporulation 6 samples with Cryptosporidium (7.59%) were detected and one with Isospora belli. Conclusion: Sporulation increases Cryptosporidium detection.