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1
artículo
Publicado 2020
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Background Pyrazinamide is an important drug against the latent stage of tuberculosis and is used in both first- and second-line treatment regimens. Pyrazinamide-susceptibility test usually takes a week to have a diagnosis to guide initial therapy, implying a delay in receiving appropriate therapy. The continued increase in multi-drug resistant tuberculosis and the prevalence of pyrazinamide resistance in several countries makes the development of assays for prompt identification of resistance necessary. The main cause of pyrazinamide resistance is the impairment of pyrazinamidase function attributed to mutations in the promoter and/or pncA coding gene. However, not all pncA mutations necessarily affect the pyrazinamidase function. Objective To develop a methodology to predict pyrazinamidase function from detected mutations in the pncA gene. Methods We measured the catalytic constant (k(...
2
artículo
Publicado 2010
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Antes de haberse formalizado el concepto del Análisis Multiresolución (AMR), la construcción de bases orto normales de ondículas debió ser demasiado dificultoso. Por ello, el estudio del AM R adquiere importancia y por consiguiente la construcción de Ondículas se hace viable. En la construcción de una ondicula Ψ, debemos determinar una función escala Φ, para luego construir su Análisis Multiresolución asociado; en seguida se pasa a construir Ψ, con propiedades deseadas para las aplicaciones.
3
artículo
Publicado 2010
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Before the concept has been formalized Analysis Multiresolution AMR, base construction orthonormal wavelet should be too difficult. For Therefore, the study of AM R becomes important and therefore construction of Wavelets is viable. In the construction of a wavelet Ψ, we determine a scale function Φ, then build your Analysis Associated multiresolution; soon passed has built Ψ with desired properties for applications.
4
artículo
Publicado 2015
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It discloses the experience gained in the radioimmunoassay determination of prolactin (PRL) levels, both in terms of methodology and clinical. Normal, preliminary figures, obtained in 4 women and 4 normal males ranged from 3 to 26 ng / ml, average 17.4 ng / ml. In 12 patients with galactorrhea and / or amenorrhea high concentrations ranging between 33 and 195 ng / ml was found. One of 2 patients under sedative treatment presented hyperprolactinemia; likewise, April 2 acromnegálicos, 1 patient with "non-functioning" and impotence and 1 patient with primary hypothyroidism pituitary tumor. Conversely, 1 patient with panhypopituitarism traumatic fracture because of the skull base was not dosables PRL concentrations. Proof of I-dopa, held in 9 patients with galactorrhea and / or amenorrhea and in patients with pituitary tumor, revealed two types of responses: in 4 cases there is some variati...
5
artículo
Publicado 2015
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It discloses the experience gained in the radioimmunoassay determination of prolactin (PRL) levels, both in terms of methodology and clinical. Normal, preliminary figures, obtained in 4 women and 4 normal males ranged from 3 to 26 ng / ml, average 17.4 ng / ml. In 12 patients with galactorrhea and / or amenorrhea high concentrations ranging between 33 and 195 ng / ml was found. One of 2 patients under sedative treatment presented hyperprolactinemia; likewise, April 2 acromnegálicos, 1 patient with "non-functioning" and impotence and 1 patient with primary hypothyroidism pituitary tumor. Conversely, 1 patient with panhypopituitarism traumatic fracture because of the skull base was not dosables PRL concentrations. Proof of I-dopa, held in 9 patients with galactorrhea and / or amenorrhea and in patients with pituitary tumor, revealed two types of responses: in 4 cases there is some variati...
6
artículo
Publicado 2019
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Intelligence is a construct of notable impact in our sociocultural context, related to a wide range of conceptual and operational definitions which originate positions that highlights cognitive and abstract elements and emotional and social skills, as well was perspectives that are focused on processes underlying the intelligent performance, such as in the case of executive functions (EFs), which are configured as cognitive processes that make it possible the self-regulation (Miyake & Friedman, 2012). Similarly, there are approaches that give intelligence a relevant and predictive role of school performance, an aspect strengthened by the psychometric perspective, where the concept of intelligence has been closely linked to learning. In this line, we also find the classical perspective of crystallized Intelligence of Cattell (1943), which refers to the knowledge acquired through educa...
7
artículo
Publicado 1962
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In this paper, systematically describes the technology developed in this laboratory for the analysis of skeletal muscle, taken as an expression of the cellular phase of the organism, which is a great tool for future research on the changes that would occur in the intracellular environment during various pathological processes, or in many other biological problems. In our particular case, and as part of the curriculum of renal failure, we want to establish if it means intracellular biochemical changes, as with the extracellular environment, or whether its composition is more or less independent of renal function.
8
artículo
Publicado 2024
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The purpose of the present paper is to improve the global convergence results established so far concerning the Augmented Lagrangian Algorithm with exponential penalty function for solving nonlinear programming problems with equality and inequality constraints. We prove global convergence for KKT points under the PAKKT-regular constraint qualifications, which results as a consequence that accumulation points generated by the algorithm are PAKKT points. This convergence result is new for the augmented Lagrangian Method based on the exponential penalty function. An interesting consequence is that the estimates of the Lagrange multipliers computed by the method remain bounded in the presence of the quasi-normality condition. Finally we give optimality and feasibility results for the convex case.
9
tesis de maestría
Publicado 2024
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Los modelos geoestadísticos gaussianos son útiles cuando los datos siguen una distribución normal. Sin embargo, cuando la distribución de los datos es simétrica pero hay presencia de observaciones atípicas entonces se debe asumir una distribución simétrica con colas más pesadas. Por otro lado, en estos modelos geoestadísticos cuando se tienen muchos datos, el principal problema para la inferencia radica en la matriz de covarianza asociada al modelo. En este contexto, esta tesis se ha centrado en extender modelos geoestadísticos usando la distribución normal independiente a través de una función de covarianza tapering o reducida. La función de reducción en la covarianza permite que la matriz de covarianza sea dispersa, característica muy útil en bases de datos grandes. Para la estimación a través de inferencia clásica se propone usar la aproximación de Laplace, para ...
10
artículo
Publicado 2023
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Objective: To identify the associated factors and assess the inequalities of full vaccination coverage (FVC) among Peruvian infants aged 12–23 months during the COVID-19 pandemic in a nationally representative sample. Methods: We carried out a population-based cross-sectional study based on a secondary data analysis using the 2021 Peruvian Demographic Health Survey (DHS) in infants aged 12 to 23 months. The sampling design was probabilistic, multistage, stratified, and independent at both departmental and area of residence levels. FVC was defined according to the WHO definition. We performed generalized linear models (GLM) Poisson family log link function to estimate crude (aPR) and adjusted prevalence ratios (aPR). Also, for inequality assessment, we calculated the concentration curve (CC), concentration index (CI), and Erreygers normalized concentration index (ECI). Results: We inclu...
11
artículo
Publicado 2025
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In Mexico, a high percentage of young people experience symptoms of generalized anxiety, which are associated with difficulties in executive functions (EF). However, previous studies have shown inconsistent results, as they often rely solely on either objective or subjective measures. Therefore, this study focused on analyzing the relationship between generalized anxiety and EF using both a neuropsychological battery and a self-report questionnaire, in order to provide a more comprehensive understanding of cognitive functioning in adolescents. A quantitative, non-experimental, cross-sectional, correlational, and explanatory design was employed. The sample consisted of 96 adolescents between 12 and 15 years old from the state of Puebla, Mexico. A total of 10.41% of participants presented severe symptoms of generalized anxiety. A significant relationship was found between anxiety and one o...
12
objeto de conferencia
We present the simulation of the application of the Model-based Predictive Control (MPC) of the drum level in a Combined Cycle Plant in order to minimize the time for reaching the highest capacity of plant, around 225 MW. In contrast to others control techniques, our simulation yields that the MPC has shown capabilities as to reach its expected power in about 40 minutes before than PID, time which normally takes the whole industrial process under this control. In the present study, we have tested up to three different reference functions in order to compare performance during the drum level control. According to the simulations, the MPC working together with these reference functions is seen to be promising in the sense of providing efficiency to the plant from the startup until the time when system is reaching 225 MW. We have also calculated a minor discrepancy of order of lees than 5%.
13
artículo
El documento a texto completo no se encuentra disponible en el Repositorio de la Universidad Autónoma del Perú debido a las restricciones de la casa editorial donde se encuentra publicada.
14
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
15
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
16
artículo
En el presente trabajo, consideramos el problema de minimizar una función continua, cuasiconvexa y Holder sobre el conjunto optimal, no necesariamente diferenciable. Para esto utilizamos las direcciones normalizadas del cono normal de los conjuntos de nivel de la función y elegimos los pasos basándonos en el conocimiento del valor óptimo de la función objetivo, también presentamos un ejemplo y su implementación computacional en Matlab.
17
artículo
In this work, we consider the problem of minimizing a quasiconvex, continue and Hölder function on the set optimal, not necessarily differentiable. We use the normalized direction of the normal con e of the set level of function and employ the stepsize rule based in knowledge of the optimal value of the objective function; we also present an example and us computational implementations in Matlab.
18
artículo
HIV-associated neurocognitive disorder (HAND) is not a well recognized entity but has high prevalence and impact in individuals infected with HIV. The term HAND encompasses a spectrum of progressive central nervous system (CNS) involvement, ranging from asymptomatic neurocognitive impairment and minor neurocognitive disorder through to the most severe form of HIV-associated dementia (HAD). While the incidence of HAD has declined significantly with highly active antiretroviral treatment (HAART), the milder forms of HAND have increased. In this review, updated nomenclature and research case definitions to guide HAND diagnosis are described. Clinical manifestations, diagnosis and treatment recommendations are also outlined. Finally, while neurocognitive impairment is typically diagnosed with full neuropsychological evaluation, the interpretation of test results is based on comparing the pat...
19
artículo
Estimation of nitrogen content in sugarcane based on vegetation indices derived from Sentinel-2 data
Publicado 2025
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Sugarcane occupies a large territorial scale in the world and is constantly searching for mechanisms to monitor nutrients in the crop production cycle, using non-destructive methods. The study aimed to estimate the nitrogen content in the sugarcane leaf was developed in the 2021/2022 harvest on two commercial fields of dryland cultivars (RB867515 = 50.75 ha) and (CVSP7870 = 48.56 ha) at the Serranópolis-Goiás mill, evaluating the efficiency of the biochemical vegetation indices Fraction of Absorbed Photosynthetically Active Radiation (fAPAR) and Canopy Chlorophyll Content (CCC) processed using the radiation transfer model RTM PROSAIL, compared to the Normalized Difference Vegetation Index (NDVI) and Green Normalized Difference Vegetation Index (GNDVI), processed using mathematical band ratio models. Both were based on a time series of Sentinel-2 data as input variables. The validation ...
20
artículo
Publicado 2024
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THIS RESEARCH PROJECT IS CARRIED OUT TO MEASURE THE CONTAMINATED AIR AND THE CONCENTRATION OF SUSPENDED PARTICLES RANGING BETWEEN 2.5ΜG AND 10ΜG ALSO KNOWN AS PM10 AND SUSPENDED PARTICLES SMALLER THAN 2.5ΜG KNOWN AS PM2.5, IN THE, DISTRICT OF VENTANILLA AND MI PERU, IN PERU. THE WORK CONSISTS OF MEASURING CO2 AND PM2.5 AND PM10 POLLUTION TO PREVENT THE HEALTH OF THE INHABITANTS OF THE AREA UNDER STUDY. THE IMPLEMENTATION OF A SYSTEM TO MEASURE THE CO2 CONTAMINATED AIR AND THE CONCENTRATION OF PM10 AND PM2.5 POLLUTANTS IS CARRIED OUT. THE MEASUREMENT SYSTEM CONSISTS OF A DUST AND CO2 SENSOR, THE SYSTEM ALSO INCLUDES AN AMBIENT TEMPERATURE AND HUMIDITY SENSOR, A DHT11 SENSOR FOR THE MEASUREMENT OF AMBIENT TEMPERATURE AND HUMIDITY, AND AN ESP8266 MODULE FOR WIRELESS RECORDING AND CLOUD RECORDING. THE SENSOR VALUES ARE PROCESSED BY AN ARDUINO UNO R3 CARD AND ESP8266 VIA WIFI. A CLOUD COMP...
