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https://purl.org/pe-repo/ocde/ford#5.02.04 18 ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades 15 https://purl.org/pe-repo/ocde/ford#6.04.08 14 https://purl.org/pe-repo/ocde/ford#3.02.26 13 https://purl.org/pe-repo/ocde/ford#5.03.01 13 https://purl.org/pe-repo/ocde/ford#3.02.10 12 Aged 11 más ...
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1
tesis doctoral
Mycobacterium tuberculosis (Mtb) sigue siendo uno de los patógenos más mortales a nivel mundial, a pesar de ser una enfermedad prevenible. La tuberculosis (TB) se trata con una combinación de cuatro medicamentos antituberculosos de primera línea: rifampicina (RIF), isoniacida, pirazinamida y etambutol, para cepas sensibles a los medicamentos. Entre estos, la RIF es uno de los agentes más potentes para controlar la enfermedad. Sin embargo, la resistencia a la RIF conlleva la aparición de casos de TB resistente a la RIF (RR-TB) o multidrogo resistente (MDR-TB). El mecanismo principal de resistencia implica mutaciones en el gen rpoB, que es responsable de aproximadamente el 95% de los casos. No obstante, todavía se están identificando otros mecanismos moleculares y condiciones que podrían contribuir a la propagación de las poblaciones RR-TB y MDR-TB. Esta investigación doctoral s...
2
artículo
The sequence of a comprehensive oral rehabilitation is described in a patient with generalized loss of tooth structure, highlighting the importance of restoring stomatognathic system function through a multidisciplinary approach. The patient was a 57-year-old woman diagnosed with occlusal disharmony, generalized attrition due to parafunction, mild dental crowding, defective restorations, carious lesions, and partial mandibular edentulism. Treatment was performed in two phases: initially, an esthetic mini-JIG was used, and occlusion was stabilized by increasing the vertical dimension using stamped composite resins restorations. In the second phase, veneers, vonlays, and implant-supported crowns were placed in the maxilla, along with a removable partial denture in the mandible, followed by delivery of a protective occlusal splint. The combination of analog and digital techniques allowed fo...
3
artículo
The study investigates the phytochemical profiles of selected wild local vegetables in Central Kalimantan, Indonesia, assessing their potential health benefits in addressing nutritional deficiencies prevalent in the region. A comprehensive analysis was conducted on key metabolites, including phenols, flavonoids, carotenoids, alkaloids, phytosterol, terpenoid, saponin, and glucosinolates. The vegetables examined in this study included Solanum torvum, Cnesmone javanica, Gymnopetalum cochinense, Stenochlaena palustris, Helminthostachys zeylanica, Nauclea orientalis, Neptunia oleraceae, Crinum sp., Etlingera elatior, Calamus sp., Solanum ferox, Colocasia esculenta, Diplazium esculentum, and Rorippa indica. Using the Folin-Ciocalteu method, the total phenolic content in the ethanolic extract ranged from 107.20 to 7393.10 mg GAE 100 g-1. Total flavonoids varied from 27.17-1163.82 mg QE 100 g-1...
4
artículo
Introduction. Hip fractures are a group of frequent pathologies in frail older adults, with a negative impact on functionality. Objective. To determine the clinical, functional, mental, and social characteristics based on the comprehensive geriatric assessment. Methods. 445 patients were evaluated, comorbidity was measured with the Charlson index, baseline functional state with the Barthel index and the Lawton and Brody scale, mental state with the Pfeiffer questionnaire, delirium using the Confusion Assessment Method and social assessment with the Gijón Socio-Family Scale. Categorical variables were presented as absolute value and percentage and continuous variables as mean and standard deviation. Results. The female sex represented 71.5%, the average age in women was 81.58 years and in men 82.58 years. Visual impairment was 48.8% and hearing impairment 46.1%. 46% had more than one com...
5
artículo
Author contribution: All authors made an equal contribution to the development and planning of the study. Conflict of Interest: The authors have no potential conflicts of interest, or such divergences linked with this research study. Data Availability Statement: Data are available from the authors upon request.
6
artículo
The research objective was to establish the relationship that exists between family functioning and the levels of learning achievement of the students of the Alipio Ponce Vásquez Educational Institution in Puerto Maldonado. The research approach was quantitative, the design was non-experimental and the descriptive type was cross-sectional correlational. The population was made up of all the fifth and sixth grade students of the primary level of the Alipio Ponce Vásquez Educational Institution and a sample of 96 students was used, which was obtained by means of a probability sampling. The technique used for data collection was the survey, in the case of the variable family functioning and the documentary analysis in the case of the variable levels of learning achievement. On the other hand, the data collection instruments were the Family Cohesion and Adaptability Assessment Scale and th...
7
artículo
The research objective was to establish the relationship that exists between family functioning and the levels of learning achievement of the students of the Alipio Ponce Vásquez Educational Institution in Puerto Maldonado. The research approach was quantitative, the design was non-experimental and the descriptive type was cross-sectional correlational. The population was made up of all the fifth and sixth grade students of the primary level of the Alipio Ponce Vásquez Educational Institution and a sample of 96 students was used, which was obtained by means of a probability sampling. The technique used for data collection was the survey, in the case of the variable family functioning and the documentary analysis in the case of the variable levels of learning achievement. On the other hand, the data collection instruments were the Family Cohesion and Adaptability Assessment Scale and th...
8
tesis de grado
El objeto de estudio de la presente investigación fue analizar de qué manera la tutela jurisdiccional efectiva, puede coadyuvar a la materialización del derecho a la tenencia compartida; bajo un enfoque cuantitativo y de diseño teoría fundamentada, logrando así obtener que la actividad jurisdiccional sea decisiva para la materialización del derecho a la Tenencia Compartida, pues esta garantizará que ambos padres tengan las condiciones ideales para desarrollar la tenencia bajo los cánones de una vida digna. Asimismo, pretende promover el ejercicio del derecho a la paternidad responsable, es decir, el actuar consciente de cada uno de los padres en la educación integral de sus hijos permitirá forjarse un futuro personal, familiar, académico y/o laboral; finalmente, incide en el libre desarrollo de la personalidad y proyecto de vida de cada uno de sus hijos, quienes podrán arrib...
9
artículo
Objective: This is to develop the architectural design of the type III hospital in Colonel Gregorio Albarracin Lanchipa District, to overcome the shortage of health infrastructure, enabling better service, so a comprehensive health system and better quality of life for population. Method: For the study and development Descriptive research was used to obtain information on health issues in the field of study. Experimental design was also used, allow to propose an adequate hospital infrastructure for the city of Tacna. Finally interviews, l iterature exploration, photographic record and reliable cases projects were conducted. Results: The study site needs to improve care medical facilities and that has no infrastructure to specialized care, the same may have radii of service, catering to the population of districts closest to this, both in infrastructure and specialized equipment and other...
10
artículo
Objective: This is to develop the architectural design of the type III hospital in Colonel Gregorio Albarracin Lanchipa District, to overcome the shortage of health infrastructure, enabling better service, so a comprehensive health system and better quality of life for population. Method: For the study and development Descriptive research was used to obtain information on health issues in the field of study. Experimental design was also used, allow to propose an adequate hospital infrastructure for the city of Tacna. Finally interviews, l iterature exploration, photographic record and reliable cases projects were conducted. Results: The study site needs to improve care medical facilities and that has no infrastructure to specialized care, the same may have radii of service, catering to the population of districts closest to this, both in infrastructure and specialized equipment and other...
11
artículo
The aim of the present study was to examine the relationship between students’ cognitive and self-regulatory strategies, academic engagement, and academic achievement in higher education, analyzing the mediating role of reading comprehension. Different tasks to assess the constructs were administered to 209 students (Mage = 21.71; SD = 4.36). The students' GPA was used as a measure of academic achievement. Significant associations were found between cognitive and self-regulation strategies, academic engagement, reading comprehension, and students' GPA. In addition, a positive association was found between cognitive and self-regulation strategies and academic engagement. Finally, the structural equation model showed that cognitive and self-regulation strategies and academic engagement have direct effects on students' GPA. Additionally, an indirect effect of cognitive and self-regulation...
12
artículo
In Mexico, a high percentage of young people experience symptoms of generalized anxiety, which are associated with difficulties in executive functions (EF). However, previous studies have shown inconsistent results, as they often rely solely on either objective or subjective measures. Therefore, this study focused on analyzing the relationship between generalized anxiety and EF using both a neuropsychological battery and a self-report questionnaire, in order to provide a more comprehensive understanding of cognitive functioning in adolescents. A quantitative, non-experimental, cross-sectional, correlational, and explanatory design was employed. The sample consisted of 96 adolescents between 12 and 15 years old from the state of Puebla, Mexico. A total of 10.41% of participants presented severe symptoms of generalized anxiety. A significant relationship was found between anxiety and one o...
13
artículo
Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been observed both within and among individuals, but the genetic factors responsible for this variation are largely unknown. The goals of this research, therefore, were to assemble, characterize, and annotate the fruit transcriptome of M. dubia in order to reconstruct metabolic pathways and determine if multiple pathways contribute to AsA biosynthesis.RESULTS: In total 24,551,882 high-quality sequence reads were de novo assembled into 70,048 unigenes (mean length = 1150 bp, N50 = 1775 bp). Assembled sequences were annotated using BLASTX against public databases such as TAIR, GR-protein, FB, MGI, RGD, ZFIN, SGN, WB, TIGR_CMR, and JCVI-CMR with 75.2 % of unigenes having annotations. Of the...
14
artículo
Technological innovation engages with new journalism narratives in a context marked by a wide information offer, in which the media try to differentiate themselves and generate more interactivity towards their audiences. This investigation analyses the use of Augmented Reality as an informative tool on Antena 3 news, in the period between January and April 2019. This Spanish television channel is a pioneer in the implementation of this display technology that recreates immersive situations superimposing physical and virtual realities. The main objective is identifying topics that use AR most, as well as determine their form, interactivity level and main functions. With a clear informative purpose, these resources are mainly associated with news of general interest, normally with a certain prevision or durability. Additionally, this study outlines main characteristics of a surrounding inn...
15
artículo
Technological innovation engages with new journalism narratives in a context marked by a wide information offer, in which the media try to differentiate themselves and generate more interactivity towards their audiences. This investigation analyses the use of Augmented Reality as an informative tool on Antena 3 news, in the period between January and April 2019. This Spanish television channel is a pioneer in the implementation of this display technology that recreates immersive situations superimposing physical and virtual realities. The main objective is identifying topics that use AR most, as well as determine their form, interactivity level and main functions. With a clear informative purpose, these resources are mainly associated with news of general interest, normally with a certain prevision or durability. Additionally, this study outlines main characteristics of a surrounding inn...
16
artículo
Earth's behavior comprehension can be achieved by the analysis of Remote Sensing data, but considering the unprecedented volumes of information currently provided by different satellites sensors, the problem can be regarded as a big data problem. Machine learning techniques have the potential to improve the analysis of this type of data; however, most current machine learning algorithms are unable to properly process such huge volumes of data. In the attempt to overcome the computational limitations related to Remote Sensing Big Data analysis, we implemented the K-Means algorithms, a clustering technique, as distributed solution, exploiting the capabilities of cloud computing infrastructure for processing very large datasets. The solution was developed over the InterCloud Data Mining Package, which is a suite of distributed classification methods, previously employed in hyperspectral ima...
17
artículo
The presentation of the cyber language as one of the variations of the language includes a discussion on its nature as an intermediate form between oral language and written language and the forces responsible for the linguistic changes. On the one hand, we have the popular usage that has given rise to the constant evolution of the language and, on the other hand, the educated speech which strives to recover its etymological form (Betancourt, 2010). The objective of the present study is to analyze the linguistic phenomena present in the texts listed on the Facebook page called “Confessions” of 6 Peruvian universities, 3 from the city of Arequipa and 3 subsidiaries of Lima universities in this city. The corpus consists of 70 texts, the design is transversal, descriptive and documentary and we used as a tool a registration form of linguistic variations in which spelling, lexical-semant...
18
artículo
The presentation of the cyber language as one of the variations of the language includes a discussion on its nature as an intermediate form between oral language and written language and the forces responsible for the linguistic changes. On the one hand, we have the popular usage that has given rise to the constant evolution of the language and, on the other hand, the educated speech which strives to recover its etymological form (Betancourt, 2010). The objective of the present study is to analyze the linguistic phenomena present in the texts listed on the Facebook page called “Confessions” of 6 Peruvian universities, 3 from the city of Arequipa and 3 subsidiaries of Lima universities in this city. The corpus consists of 70 texts, the design is transversal, descriptive and documentary and we used as a tool a registration form of linguistic variations in which spelling, lexical-semant...
19
artículo
The presentation of the cyber language as one of the variations of the language includes a discussion on its nature as an intermediate form between oral language and written language and the forces responsible for the linguistic changes. On the one hand, we have the popular usage that has given rise to the constant evolution of the language and, on the other hand, the educated speech which strives to recover its etymological form (Betancourt, 2010). The objective of the present study is to analyze the linguistic phenomena present in the texts listed on the Facebook page called "Confessions" of 6 Peruvian universities, 3 from the city of Arequipa and 3 subsidiaries of Lima universities in this city. The corpus consists of 70 texts, the design is transversal, descriptive and documentary and we used as a tool a registration form of linguistic variations in which spelling, lexical-semantic a...
20
artículo
The present study explores the application of virtual reality (VR) as an innovative therapy in treating schizophrenia, a condition that presents significant challenges with existing therapeutic approaches. Through a comprehensive bibliometric review using Web of Science, Scopus, and the Bibliometrix package, this work analyzes 252 articles, highlighting the growing prominence of VR in research. The results indicate growing international collaboration, with the UK, US, and Canada leading in contributions. Keyword analysis underscores a focus on “virtual reality exposure therapy,” suggesting growing interest in this modality. The findings support the potential of VR to improve the quality of life of patients, alleviating symptoms and improving social and cognitive functions. This analysis highlights the need for more research to optimize and validate VR as a therapeutic tool, pointing ...