Objective: To study human bartonellosis cases at Monzon valley and to determine the Lutzomyia species that may play a role in the transmission of the disease in the area. Material and methods: Carrion’s disease cases were studied at the deep jungle Monzon valley, Huamalies province, Huanuco, where and epidemic outbreak occurred between 1997 and 1998. Diagnosis was done by blood smear, culture and serology. CDC light traps and Shan-non trap in intra y peridomiciliary ambient were used for phlebotominae sandflies capture. Results: At 21 places the disease affected 140 people, 25 between 1 and 4 year-old, 81 women and 59 men; 121 presented the acute phase of the disease, 16 the intercalar phase and 3 the eruptive phase. The area population cutivates coca, coffee and cacao. Conclusion: Monzon valley is a new endemic area of human bartonellosis where transmission is mainly in intra and peri...

Objectives: To determine the composition of Lutzomyia species at the Rimac valley. Material and methods: The area studied was the Ullupampa annex (2000 msnm), San Jeronimo de Surco district, Huarochiri province, Lima. The sandflies were captured using Shannon traps, CDC light traps and direct capture, in intra and peridomiciliary ambient and natural refuges. Results: We identified 1742 phlebotomine sandflies of the Lutzomyia genus, 52,6% corresponded to Lutzomyia verrucarum, 28,2% to Lutzomyia peruensis, and 19,2% to Lutzomyia noguchi; the first two were more abundant in intra and peridomiciliary ambients, and the latest in natural refuges. Lutzomyia density presents seasonal variations, mostly found between March and May. Night activity peak is between 20 and 21 hours. Conclusions: Fruit cultivations surrounded housings separated by “pircas” and domestic animals within the house fav...

Objectives: To determine the epidemiology of cutaneous leishmaniasis. Material and Methods: Personal interviews were done to 727 inhabitants of 140 houses in eight localities of Llaucano valley, Chota province, Cajamarca, searching for leishmaniasis cases. The risk factors were analyzed using odds ratio calculation, 95% confidence interval in each selected variable and Epi Info 2000 program. Results: Two hundred and six cutaneous leishmaniasis cases were diagnosed, 63 with active lesions and 143 with scars. Leishmaniasis was present in all age groups without sex differences, but children under 10 years old were more affected. High percentage of cases showed lesions in face and arms suggesting intra and peridomiciliary transmission at Llaucano valley. The risk factors for leishmaniasis transmission were identified as following: To have the house located in the rural area (OR=3,97, CI95% 1...

Objetivos: Caracterizar las moléculas de respuesta humoral anti Paragonimus mexicanus/P. peruvianus para diferenciar la infección en fase aguda y fase crónica, mediante la evaluación de la dinámica de la respuesta inmune. Diseño: Observacional, longitudinal. Institución: Instituto de Medicina Tropical Daniel A. Carrión, Facultad de Medicina, UNMSM Material biológico: Animales de experimentación. Principales medidas de resultados: Determinación de IgG e IgM anti Paragonimus. Resultados: Existió diferencia significativa de medias de la DO entre los grupos crónico y no infectados para los anticuerpos IgG anti ES de Paragonimus. Los anticuerpos IgM anti Paragonimus tuvieron una ligera elevación entre los días 7 a 20 post inoculación (pi), y una tendencia hacia la disminución entre los días 40 y 60 pi. Conclusiones: La dinámica de producción de anticuerpos IgG e IgM anti P...

Objetivos: Detectar el genoma proviral de HTLV-1 mediante el desarrollo de reacción en cadena de la polimerasa (PCR). Diseño: Descriptivo. Institución: D.A. Microbiología Médica, Facultad de Medicina, UNMSM. Participantes: Personas con y sin sospecha de HTLV-I. Principales medidas de resultados: detección de HTLV-1 mediante PCR. Resultados: El 71,4% de los pacientes con sospecha clínica de HTLV-I fue reactivo por métodos Inmunológico. Elisa HTLV I-II Biokit detectó 5 casos reactivos (X=2,359 ± DE: 0,7309); los dos casos con sospecha clínica de HTLV- I fueron no reactivos (DO: 0,007 y 0,04); los tres casos con antecedente clínico de estrongiloidiosis fueron no reactivos al Elisa (DO: 0,029, 0,001 y 0,00). El promedio de los sueros no reactivos con antecedente clínico de HTLV-1 y estrongiloidiosis fue 0,0154 ±0,018. En el grupo de voluntarios sanos, el promedio de las DO fue...