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Evidence-based medicine has improved the safety and efficacy of medical treatments to improve people's health; Even in public health, sufficient evidence to support preventive interventions is a special need in countries with limited budgets, since these countries cannot afford to carry out interventions without evidence of support. Continuing with this model involves two important issues: the first is that decision makers and treating physicians are able to access the best available evidence to support their interventions; likewise, to be able to differentiate good quality publications and avoid supporting their actions in methodologically deficient studies or with important biases, since this could put the patient's health at risk. Because the concept of evidence-based medicine could be considered relatively new, young doctors have some advantage in this regard, since they were trained...
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artículo
Publicado 2021
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Introduction: Co-infection between other microorganisms and SARS-CoV-2, such as viruses, bacteria and fungi, is an important factor in the management of COVID-19, which could increase the difficulties in diagnosis, management, prognosis, and even increase the mortality. Objectives: The objective of this review is to describe the published scientific evidence regarding coinfection in patients with COVID-19. Methods: A bibliographic search of studies published in Spanish or English was carried out using the PubMed, The Cochrane Library and Google Scholar search engines. Studies published between January 2020 and January 24, 2021 were assessed. Results: 25 articles from various continents (America, Asia and Europe) were included. All the studies had patients with a confirmed diagnosis of COVID-19 added to some other test that ...
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artículo
Publicado 2019
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Evidence-based medicine has improved the safety and efficacy of medical treatments to improve people's health; Even in public health, sufficient evidence to support preventive interventions is a special need in countries with limited budgets, since these countries cannot afford to carry out interventions without evidence of support. Continuing with this model involves two important issues: the first is that decision makers and treating physicians are able to access the best available evidence to support their interventions; likewise, to be able to differentiate good quality publications and avoid supporting their actions in methodologically deficient studies or with important biases, since this could put the patient's health at risk. Because the concept of evidence-based medicine could be considered relatively new, young doctors have some advantage in this regard, since they were trained...
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artículo
Publicado 2020
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Introducción La gastritis crónica es unas de las enfermedades más comunes en la población y varía por regiones. Existen diversos factores que influyen en su aparición. Sin embargo, no se ha estudiado a profundidad el efecto de la altura. Objetivos Determinar la asociación entre la zona altitudinal de residencia y gastritis crónica en pacientes ambulatorios de Perú. Métodos Estudio transversal analítico. Se realizó a través del análisis secundario de datos. La variable dependiente fue gastritis crónica, tomada del reporte del paciente y verificado en la historia clínica, según antecedentes patológicos mencionados durante consulta médica. La variable independiente fue la zona altitudinal de residencia (divida en baja altitud, altitud intermedia, elevada y muy elevada). Las covariables secundarias fueron edad, sexo y tiempo viviendo en altura. Se realizaron modelos lineal...
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tesis de grado
Publicado 2018
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Antecedentes: La gastritis es unas de las enfermedades más comunes en la población. Existen diversos factores que influyen en su aparición; sin embargo, no se ha estudiado a profundidad el efecto de la altura. Objetivos: Determinar la asociación entre la zona altitudinal de residencia y gastritis en pacientes ambulatorios del Perú. Métodos: Estudio observacional, analítico y de corte transversal. Se realizó a través del análisis secundario de datos. La variable dependiente fue la gastritis, tomada de la referencia dada por el mismo paciente siempre y cuando el diagnostico lo haya hecho un médico; las variables independientes fueron zona altitudinal de residencia (divida en sin altitud, altitud intermedia, elevada y muy elevada), edad, sexo y tiempo viviendo en altura. Se realizaron modelos lineales generalizados y se consideró significativo el valor p menor a 0,05. Resultados...
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tesis de maestría
Publicado 2022
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El objetivo del estudio fue determinar el rendimiento predictor de mortalidad de escalas de pronóstico en pacientes hospitalizados con COVID-19, en el Hospital Nacional Hipólito Unanue, en el año 2020. Se realizó un estudio de enfoque cuantitativo, observacional, longitudinal y retrospectivo, de alcance descriptivo. Se efectuó un análisis secundario de datos de un estudio previo, con 132 participantes después de aplicar los criterios de selección. Se utilizaron escalas pronóstico para la evaluación del rendimiento predictor de mortalidad como PREDI-CO, NEWS-2, q-SOFA, SIRS, y CRB-65, usando las curvas ROC, medición de áreas bajo la curva, sensibilidad, especificidad, valor predictivo positivo y valor predictivo negativo. Se obtuvo como resultado que la escala PREDI-CO tuvo mejor capacidad predictiva de mortalidad para COVID-19 con un punto de corte ≥6 (AUC=0.656); la escala...
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artículo
Publicado 2023
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Given the importance of the research component to respond to phenomena and problems demanded by society , At Universidad Ricardo Palma, research has been fostered and promoted as an institutional policy. The Instituto de Investigación en Ciencias Biomédicas, which reports to the Rectorate and is integrated into the Facultad de Medicina Humana, has been working to contribute substantially to this growth in research. The research is directly related to the quality processes of higher education, innovation, extension, linking, licensing, accreditation, and finally, the ranking of universities. As is evident, the research is linked to the present and the future of universities. Therefore, measuring the impact of research is essential because educational institutions are and must be permanent generators of intellectual property, knowledge and human resources, which impact the educational...
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artículo
Publicado 2022
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Write about achievements and and outlook of research in the last ten years from the Instituto de Investigaciones en Ciencias Biomédicas (INICIB) of Universidad Ricardo Palma, it is relevant because research currently occupies a central place in universities, at least rethorically.We present an overview of the evolution of scientific publication, which constitute a real and objective indicator to visualize the trends and projections of research at the Faculty of Human Medicine and at Universidad Ricardo Palma. For this, we will take as reference the records of international bases of recognized prestige as SCOPUS and WEB OF SCIENCE.
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artículo
Publicado 2023
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The Revista de la Facultad de Medicina Humana de la Universidad Ricardo Palma (RFMH) reaches a momentous career achievement when indexed in the prestigious Harvard Library and the Directory of Research Journals Indexing (DRJI). This indexing reflects the journal's firm commitment to advancing medical science and public health through rigorous, high-quality publication.
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artículo
Publicado 2017
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Determinar la variación de la Hb en dos grupos de trabajadores mineros a diferentes altitudes. Metodología: Estudio analítico longitudinal realizado en una empresa privada. La Hb se obtuvo de los exámenes de entrada y los controles anuales de los trabajadores en dos sedes: a nivel del mar y en la serranía peruana (4100 msnm); por personal capacitado y con equipos calibrados a las condiciones ambientales. Se analizó su variación en el transcurso de los años con la prueba estadística PA-GEE y se obtuvieron los valores de p. Resultados: De los 376 trabajadores, el 89% (322) eran hombres, la mediana de edad era 32 años (rango: 20-57) y el 84% (304) laboraba a gran altura. En el análisis multivariado, ser varón (p < 0.001), el índice de masa corporal (IMC) (p = 0.021) y trabajar a gran altura (p < 0.001) se asociaron a la mayor variación de la Hb en el tiempo, ajustado por edad,...
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artículo
Publicado 2021
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Introduction: Most patients infected with the coronavirus disease 2019 (COVID-19) experience mild to moderate symptoms. This condition may affect multiple organs and systems, including the skin, and cutaneous manifestations are varied. Although several studies on COVID-19 have been con-ducted in Peru, to date, this type of manifestation has not been described in the Peruvian population, especially in environments with high prevalence of viral diseases that cause similar dermatological lesions, such as the Peruvian jungle. Case presentation: A 16-year-old male patient with no relevant medical history was admitted to a hospital in the Peruvian jungle due to headache, chills, general malaise, and respiratory distress. On physical examination, oxygen saturation was 89-90%, and a skin rash was observed; it was char-acterized by non-evanescent, confluent, pruritic, and symmetrical morbilliform...
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Introduction. COVID-19 infection in high-altitude districts has been a subject of study for several researchers since the incidence and transmission capacity of this virus is lower at higher altitudes. Objective. Compare the lethality of COVID-19 at different altitudes in different districts of Peru. Material and Methods. We conducted a secondary descriptive observational study based on data from the Ministry of Health, we took as a unit of analysis 1874 districts of Peru, taking the fatality rate as the dependent variable. In our main analysis, we developed a crude and cofactor-adjusted linear regression between the COVID-19 case fatality rate per million inhabitants and altitude of residence of the districts of Peru, we also carried out two sensitivity analyzes, to provide different approaches to the problem, adding two multivariate regression models as a sensitivity analysis, all the ...
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artículo
Publicado 2021
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Objetivo: determinar el efecto de la pronación consciente en la saturación de oxígeno (SaO2) en pacientes hospitalizados por COVID-19. Métodos: estudio de corte transversal analítico. La población estuvo conformada por los pacientes hospitalizados en uno de los pabellones por COVID-19 en el Hospital Nacional Hipólito Unanue durante el periodo junio a agosto del 2020. Se realizó un muestreo por conveniencia de tipo consecutivo de todos los pacientes comprendidos en el periodo de estudio. Se incluyó a pacientes hospitalizados mayores de 18 años, con el diagnóstico de neumonía por COVID-19. Fueron excluidos aquellos con algún grado de encefalopatía, post operados, gestantes, pacientes con inestabilidad hemodinámica. Se comparó la media de saturación arterial de oxígeno (SaO2) basal con la obtenida luego de una y dos horas de pronación. Asimismo, se evaluaron los factores ...
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artículo
Publicado 2021
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Objective: to determine the effect of conscious pronation on oxygen saturation in patients hospitalized for COVID-19. Methods: the present study was analytical - cross-sectional. The population was made up of patients hospitalized in one of the wards for COVID-19 at the Hospital Nacional Hipólito Unánue during the period June to August 2020. A consecutive convenience sampling of all patients included in the period of study. Hospitalized patients older than 18 years were included, with the diagnosis of COVID-19 by serological and molecular tests.Those with some degree of encephalopathy, post-operated, pregnant, patients with hemodynamic instability were excluded. The mean arterial oxygen saturation (SaO2) baseline was compared with that obtained after one and two hours of pronation. Likewise, the factors associated with the change in saturation were evaluated. Results: of the 198 hospit...
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artículo
Publicado 2019
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ABSTRACT Introduction: Male chauvinism is rooted in certain populations, but it has not been measured among those who will be responsible for healthcare. Objective: To determine the factors associated with male chauvinism among the medical students of 12 Peruvian universities. Methods: Cross-sectional multicentre analytical study, with previously collected data, which used validated tests to measure male chauvinism and strong religious beliefs. In addition, other social and educational factors were analysed and the data was crossed. Descriptive and analytical statistics were obtained. Results: In the multivariate analysis, we found an association between male chauvinism and religious non-believers (RP=1.88; 95% CI, 1.47-2.40), as well as being female (RP=0.35; 95% CI, 0.27-0.46). Of the 12 universities evaluated, the least chauvinistic university was in Lima. Using this university as a c...