A 19-year-old woman who started with respiratory symptoms and later presented subacute symptoms with behavioral and neurological disorder associated with hallucinations, aggressiveness, mutism, epileptic seizures, facial dyskinesias and fever. MRI was normal, EEG recorded delta waves, CSF and serum studies were negative for secondary causes. Treatment was initiated with acyclovir, anticonvulsants and, subsequently, she received methylprednisolone with immunoglobulin without satisfactory response. Treatment with rituximab was started, with a favorable response. The CSF panel was positive for NMDAr. It is important to recognize early the neuropsychiatric manifestations of this pathology for an opportune management having a positive impact on the long term prognosis.

Objetivo: determinar el efecto de la pronación consciente en la saturación de oxígeno (SaO2) en pacientes hospitalizados por COVID-19. Métodos: estudio de corte transversal analítico. La población estuvo conformada por los pacientes hospitalizados en uno de los pabellones por COVID-19 en el Hospital Nacional Hipólito Unanue durante el periodo junio a agosto del 2020. Se realizó un muestreo por conveniencia de tipo consecutivo de todos los pacientes comprendidos en el periodo de estudio. Se incluyó a pacientes hospitalizados mayores de 18 años, con el diagnóstico de neumonía por COVID-19. Fueron excluidos aquellos con algún grado de encefalopatía, post operados, gestantes, pacientes con inestabilidad hemodinámica. Se comparó la media de saturación arterial de oxígeno (SaO2) basal con la obtenida luego de una y dos horas de pronación. Asimismo, se evaluaron los factores ...

Objective: to determine the effect of conscious pronation on oxygen saturation in patients hospitalized for COVID-19. Methods: the present study was analytical - cross-sectional. The population was made up of patients hospitalized in one of the wards for COVID-19 at the Hospital Nacional Hipólito Unánue during the period June to August 2020. A consecutive convenience sampling of all patients included in the period of study. Hospitalized patients older than 18 years were included, with the diagnosis of COVID-19 by serological and molecular tests.Those with some degree of encephalopathy, post-operated, pregnant, patients with hemodynamic instability were excluded. The mean arterial oxygen saturation (SaO2) baseline was compared with that obtained after one and two hours of pronation. Likewise, the factors associated with the change in saturation were evaluated. Results: of the 198 hospit...