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artículo
Objetivo: determinar el efecto de la pronación consciente en la saturación de oxígeno (SaO2) en pacientes hospitalizados por COVID-19. Métodos: estudio de corte transversal analítico. La población estuvo conformada por los pacientes hospitalizados en uno de los pabellones por COVID-19 en el Hospital Nacional Hipólito Unanue durante el periodo junio a agosto del 2020. Se realizó un muestreo por conveniencia de tipo consecutivo de todos los pacientes comprendidos en el periodo de estudio. Se incluyó a pacientes hospitalizados mayores de 18 años, con el diagnóstico de neumonía por COVID-19. Fueron excluidos aquellos con algún grado de encefalopatía, post operados, gestantes, pacientes con inestabilidad hemodinámica. Se comparó la media de saturación arterial de oxígeno (SaO2) basal con la obtenida luego de una y dos horas de pronación. Asimismo, se evaluaron los factores ...
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artículo
Objective: to determine the effect of conscious pronation on oxygen saturation in patients hospitalized for COVID-19. Methods: the present study was analytical - cross-sectional. The population was made up of patients hospitalized in one of the wards for COVID-19 at the Hospital Nacional Hipólito Unánue during the period June to August 2020. A consecutive convenience sampling of all patients included in the period of study. Hospitalized patients older than 18 years were included, with the diagnosis of COVID-19 by serological and molecular tests.Those with some degree of encephalopathy, post-operated, pregnant, patients with hemodynamic instability were excluded. The mean arterial oxygen saturation (SaO2) baseline was compared with that obtained after one and two hours of pronation. Likewise, the factors associated with the change in saturation were evaluated. Results: of the 198 hospit...
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tesis de grado
El propósito del estudio está orientado a analizar el nivel de conocimientos, actitudes y prácticas ambientales que posee la población del distrito de Yunguyo sobre gestión ambiental y contaminación de la bahía del lago Titicaca. La investigación es de naturaleza no experimental, carácter transversal, descriptivo y correlacional, de nivel micro; el universo de estudio estuvo conformado por 17 343 personas mayores de 18 años que residen en la ciudad de Yunguyo; la muestra al azar simple fue de 332 habitantes urbanos. Las técnicas e instrumentos utilizados en el proceso de recolección de información estuvieron conformados principalmente por la encuesta y cuestionario; y en forma complementaria por la observación y procedimiento de registro (fuentes documentales). Los resultados son: El nivel de conocimientos sobre gestión ambiental y contaminación de la bahía del lago Titi...
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artículo
Paracoccidioidomycosis is a systemic mycosis, endemic to Latin America, caused by the dimorphicfungus Paracoccidioides spp., mainly acquired through the inhalation of spores present in theenvironment. It predominantly affects males in rural areas due to their frequent exposure tocontaminated soil. Following primary infection, the pathogen has the potential to spread viahematogenous or lymphatic routes, involving various organs and systems. The acute form ofparacoccidioidomycosis impairs peripheral T-cell function and disrupts neutrophil maturation,while the chronic form is characterized by a progressive decline of the cellular immune response,along with increased Th1-cytokine levels. Severe cases may present with hypergammaglobulinemia,reduced phagocytic capacity and immune dysregulation. The most significant risk factors includeprior immunosuppression and infectious comorbidities, such ...
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artículo
A 19-year-old woman who started with respiratory symptoms and later presented subacute symptoms with behavioral and neurological disorder associated with hallucinations, aggressiveness, mutism, epileptic seizures, facial dyskinesias and fever. MRI was normal, EEG recorded delta waves, CSF and serum studies were negative for secondary causes. Treatment was initiated with acyclovir, anticonvulsants and, subsequently, she received methylprednisolone with immunoglobulin without satisfactory response. Treatment with rituximab was started, with a favorable response. The CSF panel was positive for NMDAr. It is important to recognize early the neuropsychiatric manifestations of this pathology for an opportune management having a positive impact on the long term prognosis.
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The research was funded by FONDECYT through the project Coinfeccion por patogenos respiratorios virales y bacterianos detectados por metodos moleculares en pacientes hospitalizados por COVID-19 y su impacto en la mortalidad y desenlaces desfavorables (Convenio N degrees 044-2020-FONDECYT) and Research Vice-chancellor of Universidad Ricardo Palma.
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Acute liver failure (ALF) is a severe clinical entity that requires a rapid diagnosis and for its proper management requires adequate intensive care support and the possibility of liver transplantation. This study aimed to show clinical epidemiological characteristics of ALF and the problematics of its management in Peru.