Objetivo: Determinar los factores asociados con el éxito, abandono e irregularidad del tratamiento de la tuberculosis (TB) drogo sensible en el Perú. Métodos: Estudio observacional analítico, de nivel relacional, de cohorte retrospectiva. Se estudio todos los casos registrados en el Sistema de Información Gerencial de TB del Ministerio de Salud en el año 2017. Se utilizó la prueba de Chi2, análisis de regresión logística y se obtuvo el Odds Ratio crudo y ajustado. Resultados: De 29,646 casos registrados, se incluyeron 26,659. El éxito del tratamiento fue 85.81%, abandono 7.88% y la prevalencia de irregularidad 14.9%. Los principales factores asociados al éxito y abandono fueron: ser niño, adolescente o adulto joven, sexo femenino, tratamiento en establecimientos de Essalud, apoyo del PAN TBC, reacciones adversas a medicamentos, irregularidad, ser abandono recuperado, procede...

La finalidad del documento es fomentar el auspicio del INS en el desarrollo de actividades científico tecnológicos, realizados por terceros o en forma conjunta con la institución. Siendo su objetivo principal el establecer los mecanismos de autorización de auspicios que otorga el Instituto Nacional de Salud para la realización de actividades científicotecnológico, relacionados con la salud, por terceros o en forma conjunta con la institución.

El objetivo es evaluar las brechas en la realización de las pruebas de tamizaje de cáncer en los servicios de salud públicos, a nivel distrital en el Perú

The aim was to describe the prevalence, clinical manifestations, and associated factors of long-COVID. Bibliographic research of systematic reviews and meta-analyses was carried out in MEDLINE (through PubMed) until April 7th, 2022. 37 articles were found and 3 were included. Evidence quality was assessed via AMSTAR 2 criteria. Long-COVID prevalence is 43% (IC95%: 39% – 46%). Main clinical manifestations were weakness (41% [IC95%: 25% – 59%]), malaise (33% [IC95%: 15% – 57%]), fatigue (31% [IC95%: 24% – 39%]), concentration impairment (26% [IC95%: 21% – 32%]), and breathlessness (25% [IC95%: 18% – 34%]). Factors associated with long COVID were female sex, initial disease severity, age, and presence of comorbidities.

Background: Tuberculosis (TB) is sanitary and national research priority. Scientific production on TB in Peru has not been studied. Objectives: To analyze publications on tuberculosis (TB) done in Peru in the period 1981-2010. Design: Bibliometric study on tuberculosis in Peru. Setting: Universidad Nacional Mayor de San Marcos and Instituto Nacional de Salud, Lima, Peru. Analysis unit: Original articles including reports and series of cases completely developed in Peru or multicentre studies with participation of Peruvian settings. Interventions: Bibliographic search was performed in journals with indization in Medline, SciELO and LILACS 1981-2010. Year of publication, authors, time for realization, language, study area, publication type, study design, study field, population studied, type of research as defined by WHO, institutions participating, financing, and impact factor were regist...

La investigación biomédica es un instrumento clave para mejorar la calidad y la expectativa de vida. En estos últimos años, la investigación biomédica en nuestro país se ha desarrollado vertiginosamente y con escaso control por parte del Estado, pese que a nivel mundial se encuentran establecidas medidas formales encaminadas a proteger los derechos y el bienestar de los pacientes y las personas que participan en investigaciones

El objetivo del presente documento normalizar y regular los documentos del Sistema de Gestión (DSG) del Instituto Nacional del Perú. Las disposiciones contenidas en la presente directiva se aplican a toda creación intelectual desarrollada por los servidores públicos del Instituto Nacional de Salud, personas naturales con otro tipo de relación formal con el INS (Ejm: prácticas pre profesionales, rotación pasantía, etc.) personas jurídicas vinculadas al INS mediante acuerdos, convenios interinstitucionales y/o relaciones contractuales, con el fin de realizar actividades conjuntas de investigación científica y/o desarrollo tecnológico.

Several drugs have been proposed as therapeutic alternatives for COVID-19. An electronic systematic search of MEDLINE (via PubMed) was carried out until March 20th 2020, in order to identify the available evidence on pharmacological interventions for specific treatment of COVID-19. The quality of the evidence from clinical trials was evaluated according to the GRADE methodology. 947 publications were identified and 15 studies were selected: 3 clinical trials, 5 case series and 7 case reports. The existing evidence for hydroxychloroquine, favipiravir and lopinavir/ritonavir comes from clinical trials reporting favorable results for the first two drugs, while no benefit was observed when lopinavir/ritonavir was added to standard treatment. However, due to methodological issues, the evidence for hydroxychloroquine is very low. For favipiravir and lopi...

Texto completo en: https://repositorio.ins.gob.pe/xmlui/handle/INS/1321

El objetivo es revisar la literatura científica sobre las intervenciones farmacológicas para el tratamiento de la enfermedad por el coronavirus 2019 (COVID – 19).

Research priorities are a fundamental component of national health research systems. In the year 2021, the National Institute of Health led the process of identifying the "national research priorities in COVID-19 (SARS-CoV-2) and other respiratory viruses with pandemic potential: Preparing for the next pandemic, 2022-2026”. The process was developed following the previous methodology for identification of research priorities used by the Instituto Nacional de Salud (Perú), which was to be adapted to a virtual environment, with four phases. Six strategic objectives to be achieved were formulated and served as an umbrella for the identification of national priorities, a total of 21 research priorities were identified. It is recommended that a plan for the implementation of research priorities be formulated and executed and that the Ministry of Health, through its different instances, tak...