The aim was to describe the prevalence, clinical manifestations, and associated factors of long-COVID. Bibliographic research of systematic reviews and meta-analyses was carried out in MEDLINE (through PubMed) until April 7th, 2022. 37 articles were found and 3 were included. Evidence quality was assessed via AMSTAR 2 criteria. Long-COVID prevalence is 43% (IC95%: 39% – 46%). Main clinical manifestations were weakness (41% [IC95%: 25% – 59%]), malaise (33% [IC95%: 15% – 57%]), fatigue (31% [IC95%: 24% – 39%]), concentration impairment (26% [IC95%: 21% – 32%]), and breathlessness (25% [IC95%: 18% – 34%]). Factors associated with long COVID were female sex, initial disease severity, age, and presence of comorbidities.

Según los datos disponibles en la búsqueda electrónica, la vacuna de ARN mensajero de fabricación china ARCoVax se encuentra en Fase 3 y no se encontraron resultados preliminares.

El objetivo es sintetizar la evidencia científica publicada respecto a la eficacia y seguridad de la vacuna BNT162b2, desarrollada por Pfizer-BioNTech, contra la COVID-19 en población de 5 a 11 años

El objetivo del presente informe es brindar la evidencia disponible sobre el medicamento de Brii Bioscience basado en anticuerpos monoclonales neutralizantes contra la COVID-19.

El objetivo del presente informe es brindar la evidencia disponible sobre el medicamento de Sinopharm basado en inmunoglobulina humana contra la COVID-19

La ayahuasca es una liana que crece en la Amazonía y con la cual se prepara una sustancia con potentes propiedades psicoactivas, también denominada ayahuasca. Esta sustancia está ligada con la cosmovisión de los pueblos amazónicos que la consideran una planta espiritual y medicinal por las visiones y percepción de los efectos que produce. Las investigaciones en laboratorio muestran que la ayahuasca contiene derivados betacarbolínicos como la harmina y derivados triptamínicos como la N,N-dimetiltriptamina (DMT), moléculas que intervienen en determinados fenómenos psicodislépticos de tipo alucinatorio -visiones de seres sobrenaturales- junto a alteraciones de la conciencia del yo descritas como una sensación de muerte y renacimiento que pueden llevan al usuario de la ayahuasca a un estado de éxtasis espiritual y bienestar. Estos efectos han sido descritos en la literatura y se...

Determina las características de la población peruana que no busca atención médica por deficiencias de calidad de atención en salud según el análisis de la base de datos de la ENAHO en el periodo 2005-2015. Es un estudio cuantitativo, descriptivo, retrospectivo. Utiliza como fuente de datos las bases de datos de la Encuesta Nacional de Hogares (ENAHO) en el periodo 2005- 2015. Considera como deficiencia de calidad de atención a los casos de maltrato del personal de salud, demora de atención y lejanía del centro de salud. Encuentra que existe un aumento de la proporción de personas que no buscan atención médica por deficiencia de calidad de atención en 90,0%, el aumento de la proporción por maltrato es de 368,4%, el aumento por demora en la atención aumentó en 320,2% y el aumento por lejanía es de 11%. La mayoría son mujeres, de edad comprendida entre 30 y 59 años, de ...

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Objectives. To evaluate the differences in the perception of inequality in access to health care according to the ethnic group with which Peruvian adults identify. Material and Methods. Analytical cross-sectional study conducted with a secondary analysis of data from the I National Survey of Perception of Inequalities 2022. The dependent variable was the perception of inequality in the access to health and the independent variables were sociodemographic characteristics. Differences in the perception of inequality in the access to health care according to the ethnic group were evaluated with Poisson-type generalized linear models to estimate the crude and adjusted Prevalence Ratio (aPR) for the other variables. Results. Of the 1,530 respondents, 50.2% were female and the mean age was 40.0 years (95%CI: 39.23 - 40.73). For 71.8%, access to health was very unequal. And the prevalence of a p...

Objectives: To evaluate inequalities in the distribution of diagnostic tests for dengue in Peruvian provinces. Material and Methods: Ecological study of 108 provinces. Sociodemographic characteristics (sex, age group, education level, area of residence and ethnicity) were evaluated as sources of inequality using the Oaxaca-Blinder method in Sk, Gk and Rk by decomposing the GINI index. Results: The GINI index was 0.34.  In the decomposition, there were high values of Sk in the white or mestizo group (Sk=1.07) and the urban area (Sk=0.95), while there were high values of Gk in Quechua (Gk=0.62), Aymara (Gk=0.62) and Afro-Peruvian (Gk=0.44) groups with respect to the white or mestizo group (Gk=0.19). In addition, there were high Rk values in the aimara group (Rk=0.27) and with primary education (Rk=0.20). Conclusion: Ethnicity, area of residence and level of education were the main sources...

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El objetivo es sintetizar la evidencia científica publicada respecto a la eficacia y seguridad de una dosis de refuerzo a los 3 meses luego de completar un esquema de vacunación primario contra COVID-19.

El objetivo de este artículo es presentar las pautas metodológicas establecidas en el manual de Evaluaciones Tecnológicas Sanitarias Cortas, que fueron desarrolladas por la Red Nacional de Evaluación de Tecnologías Sanitarias del Perú. El propósito del manual es estandarizar las metodologías de desarrollo de las Evaluaciones Tecnológicas Sanitarias Cortas entre las instituciones de evaluación de tecnologías de salud. Con la elaboración de este manual se busca contribuir a la toma de decisiones informada en evidencia para mejorar el acceso de la población a tecnologías sanitarias seguras y eficaces en el país.

The objective of this article is to present the methodological guidelines established in the manual of Short Health Technology Assessment, which were developed by the Peruvian National Network of Health Technology Assessments. The purpose of the manual is to standardize the methodologies of development of Short Health Technology Assessments between institutions of health technology assessment. This manual seeks to contribute to evidence-informed decision-making to improve the population's access to safe and effective health technologies in Peru

The COVID-19 pandemics required the countries to take decisions rapidly. Consequently, the National Institute of Health (INS) developed a series of documents of scientific evidence synthesis according to the Ministry of Health’s requirements. Based on these reports, the INS developed recommendations to update normative documents related to COVID-19’s management. This article describes the construction of a new methodology applied by the INS to synthesize scientific evidence during the COVID-19 pandemic. Moreover, it emphasizes the efforts and strategies used to guarantee the methodological quality and the implementation of the GRADE approach. Finally, it provides a short reflection on the limitations and challenges of using evidence to design national public policies in the future.

The COVID-19 pandemics required the countries to take decisions rapidly. Consequently, the National Institute of Health (INS) developed a series of documents of scientific evidence synthesis according to the Ministry of Health’s requirements. Based on these reports, the INS developed recommendations to update normative documents related to COVID-19’s management. This article describes the construction of anew methodology applied by the INS to synthesize scientific evidence during the COVID-19 pandemic. Moreover, it emphasizes the efforts and strategies used to guarantee the methodological quality and the implementation of the GRADE approach. Finally, it provides a short reflection on the limitations and challenges of using evidence to design national public policies in the future.