La investigación presente posee como objetivo determinar si la facturación electrónica incide en la evasión tributaria del sector farmacéutico los Olivos 2019. Esta investigación está desarrollada bajo el tipo aplicada de nivel explicativo, enfoque cuantitativo con un diseño no experimental transversal causal; utilizando un muestreo no probabilístico por conveniencia y como instrumento para la recolección de datos un cuestionario en base a escala de Likert. La validez de los instrumentos se llevó a cabo mediante el juicio de expertos y el grado de confiabilidad de la investigación se utilizó el paquete estadístico SPSS lo cual fue determinado por el Coeficiente de Alfa de Cronbach que salió 0,808 para la factura electrónica y 0,869 para la evasión tributaria. Los resultados de la investigación después de analizar los datos estadísticos demuestran que la facturación e...

The COVID-19 pandemic has put the world’s governments in an unprecedented situation in which it is necessary to make quick decisions regarding the best strategies to reduce transmission. As part of these strategies, disinfection booths in the community are being implemented in many parts of the world. This document seeks to evaluate the effectiveness and safety of the disinfection booth for people to use in the community through an exhaustive search in the main bibliographic databases as well as in the main relevant institutions worldwide. After conducting the search, we found three technical documents in which the use of these technologies is not recommended because there is insufficient evidence and because they are of potential risk for people due to mucosal conditions. Another WHO recommendation document, although it does not specifically mention&...

Several drugs have been proposed as therapeutic alternatives for COVID-19. An electronic systematic search of MEDLINE (via PubMed) was carried out until March 20th 2020, in order to identify the available evidence on pharmacological interventions for specific treatment of COVID-19. The quality of the evidence from clinical trials was evaluated according to the GRADE methodology. 947 publications were identified and 15 studies were selected: 3 clinical trials, 5 case series and 7 case reports. The existing evidence for hydroxychloroquine, favipiravir and lopinavir/ritonavir comes from clinical trials reporting favorable results for the first two drugs, while no benefit was observed when lopinavir/ritonavir was added to standard treatment. However, due to methodological issues, the evidence for hydroxychloroquine is very low. For favipiravir and lopi...