Modern dental care and use of antibiotics for treatment of oral infections have made that head and neck odontogenic infections will be uncommon. To avoid acute airway obstruction, dentists must be able to recognize and treat fastly this condition. Here, we report a clinical case of a male 51 years old patient with a head and neck deep infection caused by surgical removal of the right mandibular third molar. It is showed clinical characteristics, diagnostic criteria and treatment of such infections.

Trigeminal neuralgia (TN) is a painful neuropathic condition that involves one or more branches of the trigeminal nerve. The pain produced for the TN is described as a very intense acute pain, stabbing or shooting, as an electric shock that usually occurs of form unilateral and that goes all the way of the nerve involved. It is important to make the opportune diagnosis of the condition of TN for adequately differentiate of some odontogenic painful conditions and to prevent that the patient receive unnecessary treatment. The first line of treatment of the TN is the pharmacological therapy, in which is used as a drug of first choice to carbamazepine. The second line of treatment of TN is the non-pharmacological therapy, where include various options of surgical treatment: etiologic or symptomatic.

The aim of this research was to compare systemic administration of azitromicin associated to root scaling and planning to the use of chlorhexidine mouth rinses associated to scaling and root planning, and scaling and root planning only for reducing probing depth and clinical attachment in adult patients with diagnosed of chronic periodontitis. For the trial 42 individuals with chronic periodontitis were selected, they were randomly distributed in three groups as follows: group A associated therapy of azitromicin with root scaling and planning; group B associated therapy with chlorhexidine and root scaling and planning; and group C root scaling and planning only. Probing depth and clinical attachment were recorded before treatment and every month for the next 6 months. The results showed better reduction in probing depth (before treatment: 5.70 ± 0.42 mm; during treatment: 1st month: 2.2...

Modern dental care and use of antibiotics for treatment of oral infections have made that head and neck odontogenic infections will be uncommon. To avoid acute airway obstruction, dentists must be able to recognize and treat fastly this condition. Here, we report a clinical case of a male 51 years old patient with a head and neck deep infection caused by surgical removal of the right mandibular third molar. It is showed clinical characteristics, diagnostic criteria and treatment of such infections.

Trigeminal neuralgia (TN) is a painful neuropathic condition that involves one or more branches of the trigeminal nerve. The pain produced for the TN is described as a very intense acute pain, stabbing or shooting, as an electric shock that usually occurs of form unilateral and that goes all the way of the nerve involved. It is important to make the opportune diagnosis of the condition of TN for adequately differentiate of some odontogenic painful conditions and to prevent that the patient receive unnecessary treatment. The first line of treatment of the TN is the pharmacological therapy, in which is used as a drug of first choice to carbamazepine. The second line of treatment of TN is the non-pharmacological therapy, where include various options of surgical treatment: etiologic or symptomatic.

El objetivo de la investigación fue comparar la eficacia de la administración sistémica de azitromicina asociada al raspaje y alisado radicular con la administración de enjuagatorios con clorhexidina asociados al raspaje y alisado radicular y con el tratamiento con sólo raspaje y alisado radicular, para reducir la profundidad de sondaje periodontal y mejorar los niveles de adherencia clínica en pacientes adultos con periodontitis crónica. Participaron 42 pacientes con periodontitis crónica, distribuidos aleatoriamente en tres grupos, siendo grupo A: azitromicina sistémica asociada a raspaje y alisado radicular; B: enjuagatorios con clorhexidina asociados al raspaje y alisado radicular; C: sólo raspaje y alisado radicular. Se evaluó la profundidad de sondaje periodontal y el nivel de adherencia clínica, antes de iniciar el tratamiento y luego cada mes durante los 6 meses poste...

El objetivo principal del presente estudio fue demostrar que la administración intramuscular preoperatoria de diclofenaco tiene una eficacia superior a la administración intramuscular preoperatoria de ketorolaco para prevenir el dolor posterior a cirugía de tercera molar retenida. Participaron 40 pacientes candidatos a recibir extracción quirúrgica de tercera molar inferior retenida que voluntariamente se incorporaron al estudio, asignados en 2 grupos (diclofenaco y ketorolaco) de 20 integrantes cada uno. El grupo diclofenaco recibió diclofenaco 75 mg y el grupo ketorolaco recibió ketorolaco 60 mg, en ambos casos por vía intramuscular 30 minutos antes de iniciar la cirugía. La evaluación del dolor postoperatorio fue realizada sobre 4 variables: intensidad del dolor según escala visual análoga (EVA) durante las 24 horas posteriores a la cirugía, tiempo para analgesia de resca...

The objective of this study was to determine the effects of diclofenac, etoricoxib, ibuprofen and paracetamol on the magnitude of orthodontic tooth movement. 50 Holtzman rats participated in 5 groups of 10 rats each. At the beginning of study the distance between the angles inciso-distals of both maxillary incisive was measured in each animal, using a caliper, and immediately an orthodontic device with a reciprocal action force of 35 g. was adhered to them. Each group received different treatments intraperitoneally (A: NaCl, control group, B: diclofenac, C: etoricoxib, D: ibuprofen, E: paracetamol) for 5 days. In all controls made the 1st, 3rd, 5th and 7th days, interincisive distance was significantly lower in the ibuprofen and diclofenac groups, without significant difference in the etoricoxib and paracetamol groups; all compared with control group. It was shown that administration of ...

El objetivo del presente estudio fue determinar los efectos de diclofenaco, etoricoxib, ibuprofeno y paracetamol sobre la magnitud del movimiento dentario ortodóntico. Participaron 50 ratas Holtzman distribuidas en 5 grupos de 10 ratas cada uno. Al inicio del trabajo, en cada uno de los animales, se midió la distancia entre los ángulos incisodistales de los incisivos maxilares empleando un calibrador, e inmediatamente se adhirió un dispositivo ortodóntico con una fuerza de acción recíproca de 35 g en dichos incisivos. Cada grupo recibió tratamientos diferentes por vía intraperitoneal (A: NaCl, grupo control, B: diclofenaco, C: etoricoxib, D: ibuprofeno, E: paracetamol) durante 5 días. En todos los controles hechos al 1er, 3er, 5to y 7mo día, la distancia interincisiva fue significativamente menor en los grupos ibuprofeno y diclofenaco, y sin diferencia significativa en los gru...

Objective. To determine the effect of the Croton lechleri lyophilized extract gel on root pulp tissue of pulpotomies performed on Oryctolagus cuniculus. Methods. Thirty-two two-month-old male New Zealand rabbits race, were randomly assigned into four experimental groups: a) control, b) formocresol, c) 1% Croton lechleri and d) 2.5% Croton lechleri. Four pulpotomies were done on each animal. Clinical variables (abscesses, tooth mobility and infections) and histopathological variables (fiber formation, pro-inflammatory cell and regenerative cell number) were analyzed after 1,7,15, and 30 days. Results. No clinical signs were evident in all experimental groups evaluation at any time period. In the first day histopathological evaluation, there were abundant presence of capillaries in all control group samples and half of formocresol ones, while 1% Croton lechleri and 2.5% Croton lechleri gro...

Introduction: Necrotizing fasciitis is a serious infection that involves the skin, the subcutaneous tissue, and the superficial-deep fascia, it progresses very quickly, and if not treated in time it can cause death. Report case: We present the case of an adult patient with a history of anemia, who was diagnosed with odontogenic necrotizing fasciitis, for which she underwent surgery and underwent intraoral and extraoral drainage plus escharectomy. In addition, pharmacological treatment (intravenous antibiotics) was administered, and an amniotic membrane was placed as a dressing material to reconstruct the hemorrhagic surface left by the necrotizing fasciitis. Conclusions: The amniotic membrane as a dressing material presented favorable results in the patient, obtaining a rapid regeneration of the sequel produced by necrotizing fasciitis.

Surgical antibiotic prophylaxis consists in the use of an antimicrobial drug in a preventive way, that must be active against microorganisms that in high frequency causes posterior infections of our surgical wounds and maintain effective tissue concentrations along the surgery procedure and the posterior time when appears the bacteremia. To reach a successful treatment is necessary to have the knowledge of the resident bactemial flora and the pathogenous flora that infects our surgical wounds. We must choose the correct antibiotic and use it by the correct time. Generally, that time does not exceed 24 hours and in the prophylactic schemes are used some antimicrobial drugs like beta-lactams, azalides lyncosamides and aminoglycosides, that must be selected depending of the medical condition of the patient and some topic related directly with the surgical technique employed.

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.

Surgical antibiotic prophylaxis consists in the use of an antimicrobial drug in a preventive way, that must be active against microorganisms that in high frequency causes posterior infections of our surgical wounds and maintain effective tissue concentrations along the surgery procedure and the posterior time when appears the bacteremia. To reach a successful treatment is necessary to have the knowledge of the resident bactemial flora and the pathogenous flora that infects our surgical wounds. We must choose the correct antibiotic and use it by the correct time. Generally, that time does not exceed 24 hours and in the prophylactic schemes are used some antimicrobial drugs like beta-lactams, azalides lyncosamides and aminoglycosides, that must be selected depending of the medical condition of the patient and some topic related directly with the surgical technique employed.

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.

El estudio comparó el nivel de sedación usando midazolam por vía oral combinado con gelatina y jugo de durazno en sedación consciente. Los datos se obtuvieron de 10 niños preescolares con conducta negativa que iban a ser sometidos a sedación consciente, El grupo “A” fueron 5 niños a los cuales se les administro midazolam combinado con gelatina (0.5mg/kg), vía oral , el grupo “B” fueron otros 5 niños que se les administro midazolam combinado con jugo de Durazno (0,5mg/kg) , vía oral. Se evaluó grado de aceptación, periodo de latencia, nivel de sedación y funciones vitales al inicio, durante y al final de la sedación. Se encontró un mayor grado de aceptación en los pacientes que recibieron midazolam combinado con gelatina, su inicio de acción fue mucho más rápido, empezando el tratamiento a los 22 minutos de a haber recibido el fármaco, comparado con el midazola...

Aims: Cancer is the first cause of death in the Peruvian population; searching alternative treatments of medicinal plants constitute a promissory field to find new anticancer drugs. The main objective in this study was to evaluate the phytochemical screening, total phenolic content, antioxidant and cytotoxic activity of ethanol extract of Chromolaena laevigata (C. laevigata) on human tumor cell lines. Study Design: The fresh leaves of C. laevigata were soaked with ethanol followed by phytochemical screening using standard methods. Place and Duration of Study: Laboratory of Applied Chemistry, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga de Ica, Ica, Peru; Laboratory “Abraham Vaisberg Wolach”, Universidad Peruana Cayetano Heredia, Lima, Peru. Methodology: Phytochemical screening was assessed by using chemical reactives. Total phenolic content (TPC) was de...

El estudio comparó el nivel de sedación usando midazolam por vía oral combinado con gelatina y jugo de durazno en sedación consciente. Los datos se obtuvieron de 10 niños preescolares con conducta negativa que iban a ser sometidos a sedación consciente, El grupo “A” fueron 5 niños a los cuales se les administro midazolam combinado con gelatina (0.5mg/kg), vía oral , el grupo “B” fueron otros 5 niños que se les administro midazolam combinado con jugo de Durazno (0,5mg/kg) , vía oral. Se evaluó grado de aceptación, periodo de latencia, nivel de sedación y funciones vitales al inicio, durante y al final de la sedación. Se encontró un mayor grado de aceptación en los pacientes que recibieron midazolam combinado con gelatina, su inicio de acción fue mucho más rápido, empezando el tratamiento a los 22 minutos de a haber recibido el fármaco, comparado con el midazola...

The authors thank Universidad Nacional Mayor de San Marcos for helping to support this research. Cesar Franco-Quino is a doctoral student studying an Epidemiological Researcher Doctorate at Universidad Peruana Cayetano Heredia under FONDECYT/ CIENCIAACTIVA scholarship EF033-235-2015 and supported by training grant D43 TW007393 awarded by Fogarti International Center of the US National Institutes of Health.

The aim of this study was to demonstrate that the use of irrigating solutions in surgical procedures does not alter both inflammation processes and tissue repair. Four (04) groups were formed containing 15 rats each. After being dosed with general anaesthesia, they underwent osteotomy in the tibia with tungsten carbide burs and irrigation for 15 seconds, using the following solutions in each group: A) 0,12 % chlorhexidine with cetylpyridinium 0,05 %, B) 0,12 % chlorhexidine with aspartame; C) hexetidine 0,1 %; D) 0,9 % sodium chloride. After 3, 7 and 15 days of surgery, the rats were sacrificed and tissue samples were removed for histopathological analysis. The results showed that groups in which chlorhexidine with cetylpyridinium, and chlorhexidine with aspartame were used, less inflammatory process were found than in groups of sodium chloride and hexetidine. On the process of tissue re...