El objetivo es actualizar la revisión que sintetiza la evidencia científica publicada respecto a la eficacia y seguridad de las vacunas contra la viruela del mono

Nota Técnica

Sintetizar la evidencia disponible sobre el efecto de las diversas estrategias de reapertura de escuelas implementadas por los gobiernos, en la transmisión de SARS-CoV-2, hospitalización y mortalidad en niños y adolescentes, que acuden a las instituciones educativas, durante los últimos dos años.

Nota Técnica

Nota Técnica

Nota Técnica

Introduction: Anemia is the largest nutritional problem in Peru. Objective: To determine changes in hemoglobin level according to altitude in Peruvian children in order to propose a national correction factor. Design: Descriptive, cross-sectional study. Setting: At national level. Participants: 22 500 children aged 6 to 59 months-old. Interventions: Data from the Demography and Family Health Survey (ENDES 2015) was used to select non-anemic children for the proposed formulation. An exponential regression model was used and the correction factor for hemoglobin (according to altitude) was: 8.3 *e (0,000426 * height) -12. Main outcome measure: Prevalence of anemia according to altitude. Results: The prevalence of anemia was compared according to the proposed correction factor versus the traditional formula used by the Center of Disease Control (CDC). The difference at national level reached...

This article shares the experience of the technology transfer (TT) developed by the Peruvian National Institute of Health (INS) towards the multidisciplinary clinical groups of different IPRESS and managers of the Ministry of Health (MINSA), inside the framework of the development of guidelines for Clinical Practice-Informed in Evidence (GPC-IE). It presents the evolutionary context of the CPG together with the role assumed by the INS, in their development of current regulations and in their implementation. It expresses the inherent situation to operationalization of the process that were not initially contemplated in the guideline and the contributions made to afford it; as the variability of the prioritization strategies of topics to be developed, the additional characteristics of the development group (GE) and methodology group (GM), the relevance of the management group, the pedagogi...

This article presents interventions to prevent mortality and injuries from traffic accidents (TA), from the scientific evidence and perspective of the actors involved. For this purpose, a systematic search was carried out, a policy summary was organized with the participation of key actors to finally carry out a deliberative dialogue with technical representatives of the various institutions related to the approach of the proposed problem. Describe evidence-based interventions related to education, integral infrastructure, pre-hospital assistance, regulations and control that were deliberate and contextualized to our local environment. The multi-sector technical representatives contributed considerations for its implementation, the potential benefits or damages, the use of resources, necessary adaptations, possible barriers and facilitators for its approach. It presents the channeling ro...

Introduction. Depression is a mental disorder that in its most severe form can end in suicide. Objective. This Evidence-based Clinical Practice Guideline (EB-CPG) provides recommendations for the pharmacological and psychotherapeutic treatment of depression in adults. Methods. An adapted EB-CPG was elaborated through a systematic, rigorous and transparent process with a team of methodologists and psychiatrists experts in clinical management of the disease. The guide has seven clinical questions and 10 recommendations, the search and preselection of CPGs was carried out responding to the scope and objectives, which were evaluated through the “Appraisal of Guidelines for Research and Evaluation II” (AGREE-II), and the guide with the best methodological quality was selected for methodological adaptation. A systematic search for evidence to answer the clinical questions was made in multi...

Introduction: Schizophrenia is a psychotic disorder characterized by substantive alteration of mental functioning and effects on the social functionality of affected individuals. Objective: Provide recommendations based on the best available evidence for early approach, pharmacological and psychosocial treatment. Methods: An Evidence-based Clinical Practice Guide (GPC-BE) was developed, adapted through a systematic, rigorous, transparent process, by a working group composed of methodologists and psychiatrists who are experts in the management of schizophrenia. The guide includes four clinical questions and recommendations, we searched for guides that respond to the prioritized topic, guides were pre-selected and evaluated using the “Appraisal of Guidelines for Research and Evaluation II” (AGREE-II) instrument, the one with the best methodological quality...

Introduction. In Peru, hypertensive disorders of pregnancy are the second cause of maternal mortality. Objective. This evidence-based clinical practice guideline (EB-CPG) provides recommendations for the prevention and treatment of pre-eclampsia and eclampsia. Methods. An adapted EB-CPG was elaborated through a systematic, rigorous and transparent process with a group consisting of methodologists and health professionals who are experts in the management of the disease. The guide has sixteen clinical questions and sixteen recommendations. The search and pre-selection of EB-CPGs were performed, which were evaluated through the “Appraisal of Guidelines for Research and Evaluation II” tool (AGREE-II), for its adaptation. The systematic search for evidence to answer the 16 clinical questions were made in multiple databases: MEDLINE / PubMed, EMBASE / Ovid, C...