Este artículo comparte la experiencia del proceso de transferencia tecnológica (TT) realizada por el Instituto Nacional de Salud (INS) hacia los grupos clínicos multidisciplinarios de las diversas IPRESS y direcciones del Ministerio de Salud (MINSA), dentro del marco de desarrollo de guías de práctica clínica informadas en evidencia (GPC-IE). Presenta el contexto evolutivo de las GPC junto al rol que desarrolló el INS, tanto en el desarrollo de la normativa vigente como en su implementación. Expresa las situaciones propias de la operacionalización del proceso que no fueron contempladas inicialmente en la norma y los aportes realizados para su abordaje; como la variabilidad de las estrategias de priorización de temas a desarrollar, las características adicionales del grupo elaborador (GE) y grupo metodólogo (GM), la relevancia del grupo gestor, las estrategias pedagógicas emp...

Introduction. Neonatal sepsis is a set of clinical signs and symptoms caused by a systemic infection, associated with maternal, neonatal or hospital risk factors. Objective. Provide informed recommendations for the best available evidence for the prevention, diagnosis and treatment of neonatal sepsis. Methods an Evidence-based Clinical Practice Guide (CPG) was developed through an adaptation process, in charge of a team of methodologists and neonatologists who are experts in the clinical management of neonatal sepsis. The search and pre-selection of CPGs that respond to the scope and objectives set were carried out, using the AGREE-II instrument, the methodological quality of the guides was evaluated and their adaptation decided. To identify the evidence that answers the questions in the guideline, a systematic search was carried out in multiple databases: M...

Introduction. In Peru, hypertensive disorders of pregnancy are the second cause of maternal mortality. Objective. This evidence-based clinical practice guideline (EB-CPG) provides recommendations for the prevention and treatment of pre-eclampsia and eclampsia. Methods. An adapted EB-CPG was elaborated through a systematic, rigorous and transparent process with a group consisting of methodologists and health professionals who are experts in the management of the disease. The guide has sixteen clinical questions and sixteen recommendations. The search and pre-selection of EB-CPGs were performed, which were evaluated through the “Appraisal of Guidelines for Research and Evaluation II” tool (AGREE-II), for its adaptation. The systematic search for evidence to answer the 16 clinical questions were made in multiple databases: MEDLINE / PubMed, EMBASE / Ovid, C...