Objective. Know clinical and pathological epidemiologic characteristics from HELLP Syndrome of admitted patients in the Maternal Intensive Care Unit from INMP. Materials and methods. Clinical histories from admitted patients in the Maternal Intensive Care Unit from INMP since August of 2014 to August 31st of 2016 were checked out. Furthermore, 502 records: 49 record of patients with HELLP Syndrome y 452 records of patients with preeclampsia diagnostic were included.

Objective: to acknowledge the pathological, clinical and epidemiological characteristics of early-onset severe preeclampsia and late-onset severe preeclampsia in patients admitted in the maternal intensive care unit (MICU) of the maternal perinatal national institute (INMP). Methods: We develop a comparative transversal descriptive study. Clinical charts were reviewed from August first of 2014 until September thirty of 2018 getting 332 charts of early-onset preeclampsia and 325 charts of the late-onset type. Results: The mean age of the patients with early-onset severe preeclampsia was 27.84 years (IC 26.88- 28.81) (p: 0.72), the mean for hospital stay was higher in the patients with the early-onset type (p: 0.006). The new born showed statistical difference in weight (p=0.000), height (p=0.000) and the APGAR score was lower in the early-onset group (p=0.000). We did not found difference...

Objective:  To compare the SOFA score at admission and 24 hours and evaluate its usefulness in predicting maternal death. Materials and methods: A cross-sectional descriptive study of patients admitted to the Maternal ICU of the INMP was carried out from August 2014 to July 2019. Parametric and non-parametric tests were applied according to a previous evaluation of normality and a statistical significance p<0.05. Statistical analysis was performed using the statistical package STATA version 13. Results: The mean age corresponds to 28.32 years. The mean gestational age corresponded to 31.33 weeks; The mean hospital stay was 4.52 days. The area under the curve for SOFA at entry was 0.8818 and the area under the curve for SOFA at 24 hours was 0.9755.     P=0.1225. No significant differences were found between them. It was determined that the best cut-off poi...

Objective. Know clinical and pathological epidemiologic characteristics from HELLP Syndrome of admitted patients in the Maternal Intensive Care Unit from INMP. Materials and methods. Clinical histories from admitted patients in the Maternal Intensive Care Unit from INMP since August of 2014 to August 31st of 2016 were checked out. Furthermore, 502 records: 49 record of patients with HELLP Syndrome y 452 records of patients with preeclampsia diagnostic were included.

Objective: to acknowledge the pathological, clinical and epidemiological characteristics of early-onset severe preeclampsia and late-onset severe preeclampsia in patients admitted in the maternal intensive care unit (MICU) of the maternal perinatal national institute (INMP). Methods: We develop a comparative transversal descriptive study. Clinical charts were reviewed from August first of 2014 until September thirty of 2018 getting 332 charts of early-onset preeclampsia and 325 charts of the late-onset type. Results: The mean age of the patients with early-onset severe preeclampsia was 27.84 years (IC 26.88- 28.81) (p: 0.72), the mean for hospital stay was higher in the patients with the early-onset type (p: 0.006). The new born showed statistical difference in weight (p=0.000), height (p=0.000) and the APGAR score was lower in the early-onset group (p=0.000). We did not found difference...

Objective:  To compare the SOFA score at admission and 24 hours and evaluate its usefulness in predicting maternal death. Materials and methods: A cross-sectional descriptive study of patients admitted to the Maternal ICU of the INMP was carried out from August 2014 to July 2019. Parametric and non-parametric tests were applied according to a previous evaluation of normality and a statistical significance p<0.05. Statistical analysis was performed using the statistical package STATA version 13. Results: The mean age corresponds to 28.32 years. The mean gestational age corresponded to 31.33 weeks; The mean hospital stay was 4.52 days. The area under the curve for SOFA at entry was 0.8818 and the area under the curve for SOFA at 24 hours was 0.9755.     P=0.1225. No significant differences were found between them. It was determined that the best cut-off poi...

Objective: To determine the clinical characteristics and management of subcapsular hepatic hematoma (SHH) as a result of severe preeclampsia and HELLP syndrome in the period 2004-2016. Design: Descriptive, retrospective study, series of cases type. Setting: Instituto Nacional Materno Perinatal, Lima, Peru. Material: We reviewed the clinical charts of patients with SHH. Methods: The clinical charts of cases with SHH attended at our institution between 2004 and 2016 were reviewed. Search also included PubMed and the results were compared with those in the literature. Main outcome measures: Incidence, clinical features, diagnosis, management and results. Results: 31 cases of SHH were found, with an incidence of 1 in 6 000 to 9 000 births. The mean maternal age was 34 years and 80% were multiparous. Diagnosis was usually through direct visualization of the hepatic rupture during caesarean se...

Objective. To determine the clinical and management features of hepatic sub capsular hematoma (HSH) as a result of severe preeclampsia and HELLP syndrome in the period between 2004 and 2014. Materials and methods. We reviewed the cases with HSH in our institution retrospectively. Clinical features, diagnosis, medical and surgical management were defined. Search also included PubMed. The results of our study were compared with those already published.

Objective. To determine the clinical and management features of hepatic sub capsular hematoma (HSH) as a result of severe preeclampsia and HELLP syndrome in the period between 2004 and 2014. Materials and methods. We reviewed the cases with HSH in our institution retrospectively. Clinical features, diagnosis, medical and surgical management were defined. Search also included PubMed. The results of our study were compared with those already published.

The liver rupture in pregnancy (LRP) is a disease of low incidence but high morbidity and mortality, being a devastating complication in patients with severe preeclampsia (SPE), approximately 200 cases in the world literature and some individual cases in the national literature are reported. Objectives: The main objective was to describe the most frequent clinical features in patients with SPE admitted to the Unidad de Cuidados Intensivos Materna (UCIM) at the Instituto Nacional Materno Perinatal (INMP). Materials and methods: The medical records of patients with the diagnosis of LRP treated in the UCIM in the period between 2004 and 2013 were reviewed, a record of data collection was used and frequency analysis was performed for most common signs and symptoms.

The liver rupture in pregnancy (LRP) is a disease of low incidence but high morbidity and mortality, being a devastating complication in patients with severe preeclampsia (SPE), approximately 200 cases in the world literature and some individual cases in the national literature are reported. Objectives: The main objective was to describe the most frequent clinical features in patients with SPE admitted to the Unidad de Cuidados Intensivos Materna (UCIM) at the Instituto Nacional Materno Perinatal (INMP). Materials and methods: The medical records of patients with the diagnosis of LRP treated in the UCIM in the period between 2004 and 2013 were reviewed, a record of data collection was used and frequency analysis was performed for most common signs and symptoms.

Introduction. Consultations outside the Maternal Intensive Care Unit (ICU) enable early identification of critical complicationsin obstetric patients, preventing clinical deterioration. Objective. To identify the characteristics of non-ICU consultationsand their relationship with maternal Near Miss events and ICU admission. Methods. An observational, correlational,and retrospective study was conducted, including 768 patients assessed outside the ICU at the Instituto Nacional MaternoPerinatal (INMP) between January and December 2022. Sociodemographic and clinical variables were collected. Bivariateand multivariate analyses were performed to evaluate the association between organ dysfunctions and the outcomesof Near Miss events and ICU admission. Adjusted risk ratios (RR) with 95% confidence intervals (CI95%) were estimated.A p-value <0.05 was considered statistically significant. Resul...

Introduction. In Peru, hypertensive disorders of pregnancy are the second cause of maternal mortality. Objective. This evidence-based clinical practice guideline (EB-CPG) provides recommendations for the prevention and treatment of pre-eclampsia and eclampsia. Methods. An adapted EB-CPG was elaborated through a systematic, rigorous and transparent process with a group consisting of methodologists and health professionals who are experts in the management of the disease. The guide has sixteen clinical questions and sixteen recommendations. The search and pre-selection of EB-CPGs were performed, which were evaluated through the “Appraisal of Guidelines for Research and Evaluation II” tool (AGREE-II), for its adaptation. The systematic search for evidence to answer the 16 clinical questions were made in multiple databases: MEDLINE / PubMed, EMBASE / Ovid, C...

We report the first successful case of fetal surgery for spina bifida repair in Peru. A pregnant woman was referred to our center at 23 weeks’ gestation because of prenatal diagnosis of spina bifida. We formed a multidisciplinary international team with the goal of performing the first open intrauterine surgery in Peru. We performed a successful intrauterine surgery at 25 weeks of gestation and a healthy infant was born by cesarean section at 37 weeks of gestation. We demonstrated the feasibility of this complex intrauterine surgery in our local setting.