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Dengue is an infectious disease caused by a systemic Flavovirus which is transmitted by mosquitoes of the genus Aedes aegypti and albopictus species (1). The incidence of dengue in the Americas in recent years has increased and spread in several countries, being mostly affected the tropical and subtropical regions, with an increase of the disease in urban and suburban areas, thus constituting a major public health problem, especially in developing countries (1). In Peru, in the departments of Loreto, Madre de Dios, Tumbes Cajamarca, Cusco, Lambayeque, Huanuco, La Libertad and Puno in the last year the highest number of confirmed cases was reported and increased outbreaks of dengue in the country (2 ).

Introduction: There are limited epidemiological reports of Kawasaki disease (KD) in Latin America. Objective: To describe the characteristics, seasonality, and trend of hospitalizations for KD in children. Methods: Descriptive study of secondary analysis was performed with data on hospitalizations due to KD from healthcare institutions from Peru, 2015-2019. Results: Two hundred ninety-seven hospitalizations were registered. 59.9% were male. 82.2% were under five years old, and 16.2% were under one year old. The departments with more hospitalizations were Lima (202 cases), Lambayeque (21 cases), and Piura (17 cases). The seasons of the year with more hospitalizations were winter and spring. The incidence of KD increased from 0.52 to 2.28 cases per 100,000 children under five years old between 2015 and 2019. Conclusions: There was an increase in hospitalizations due to KD, more frequent in...

Introduction. There are limited epidemiological reports of hemolytic uremic syndrome (HUS) in Latin America. Objective. To describe the frequency and characteristics of hospitalizations due to HUS in children aged 0 to 14 years. Methods. Descriptive study of secondary analysis was performed with data on hospitalizations due to HUS from healthcare institutions from Peru, 2015-2022. Results. Two hundred twenty-eight hospitalizations were registered, 52.2% were male, 88.6% were under five years old, and 11% were under one year old. The departments with more hospitalizations were Lima (133 cases) and Arequipa (46 cases). The institutions of the Ministry of Health (MINSA) and Social Security (EsSalud) reported 42.5% and 27.6% of hospitalizations. From 2015 to 2022, the incidence ranged from 0.42 to 1.13 cases/100,000 children under five years of age. Conclusions. Hospitalizations due to HUS w...

El reordenamiento genético es la combinación de segmentos de genes que se produce por la confluencia de algunos virus de la misma especie o afines, lo cual altera la infecciosidad y el grado de patogenicidad del virus. Se produce en virus con genomas segmentados, como los del género Orthobunyavirus (familia Bunyaviridae), que incluye tres segmentos de cadena simple de ARN: el S (small), el M (médium) y el L (large), y son responsables frecuentemente de enfermedad febril aguda indiferenciada (SFAI). Este es el caso de la fiebre producida por el virus Oropuche (OROV), que ha cobrado protagonismo por recientes brotes e incremento de casos en el Perú.

Introducción: Existen limitados reportes epidemiológicos de la enfermedad de Kawasaki en Latinoamérica. Objetivo: Describir las características, estacionalidad y tendencia de las hospitalizaciones por EK en niños. Métodos: Se realizó un estudio descriptivo de análisis secundario con datos de hospitalizaciones por EK de instituciones de salud de Perú en el periodo 2015-2019. Resultados: Se registraron 297 hospitalizaciones. El 59,9% fueron varones. El 82,2% fue menor de cinco años y el 16,2% menor de un año. Los departamentos con más hospitalizaciones fueron Lima, Lambayeque y Piura con 202, 21 y 17 casos. Las estaciones con mayor registro fueron invierno y primavera. La incidencia de EK se incrementó de 0,52 a 2,28 casos/100 000 niños menores de cinco años entre el 2015 al 2019. Conclusiones: Hubo un incremento de las hospitalizaciones por EK, más frecuente en niños meno...

Con el objetivo de determinar los factores asociados a las prácticas de publicación de los médicos que laboran en los hospitales de la ciudad del Cusco, Perú, se realizó un estudio de corte transversal analítico, donde se incluyó a todos los médicos de los hospitales de la ciudad en el año 2014. La búsqueda de publicaciones se realizó en las bases de datos de Google Académico, SciELO, Medline y Scopus. Los médicos del Hospital Nacional Adolfo Guevara Velasco presentaron la mayor frecuencia de publicación científica (49 %).

Introduction: The incidence of thyroid cancer has increased worldwide. Peru has few reports describing the national and regional epidemiology of thyroid cancer. Objective: The incidence of thyroid cancer has increased worldwide. Peru has few reports describing the national and regional epidemiology of thyroid cancer. Methods: A descriptive study of trends was conducted with secondary data obtained from a public information source in Peru. The ICD 10: C73.0 coding record was evaluated, by age group, year and region. The age-standardized prevalence (period 2005 to 2016) and mortality (period 2005 to 2015) were calculated by region and year of study. Results: In the 2005-2016 period, 19 513 cases of thyroid cancer were recorded. The age group with the highest frequency was 30 to 59 years (57.7%). The prevalence increased from 4.7 to 15.2 cases per 100 000 inhabitants in the period 2005-2016...

La pandemia por la enfermedad por coronavirus (COVID-19) está afectando los sistemas de salud en los países de la región. Asimismo, afecta las coberturas de vacunación en varios países del mundo (3). Esto se debe a la priorización de actividades sanitarias, sociales y económicas que han tomado los países para contener, controlar y mitigar la pandemia. Por ejemplo, en el Perú las medidas de distanciamiento social y la suspensión temporal del Programa Nacional de Inmunizaciones (PNI) han propiciado dificultades de movilización de personas y la desconfianza del personal sanitario y de la población sobre el uso de las vacunas. Esto ha generado la reacción inmediata del PNI mediante actividades de promoción para contener un probable perjuicio en las coberturas de vacunación.

Introducción La enfermedad por coronavirus 2019 ha sido reportada en la población pediátrica; sin embargo, existe limitada información en países de América Latina y El Caribe. Objetivos Describir la frecuencia de casos, defunciones, incidencia acumulada y letalidad atribuida a COVID-19 en niños y adolescentes de países de América Latina y El Caribe. Métodos Se realizó un estudio observacional utilizando los registros de casos atribuidos a COVID-19 en niños y adolescentes publicados por los Ministerios de Salud de 16 países de América Latina y tres países de El Caribe hasta el 20 de mayo de 2020. Se clasificaron los casos y las defunciones por sexo y grupo de edad. Además, se calcularon la incidencia acumulada y letalidad por cada país. Resultados Se reportaron 20 757 casos de COVID-19 de 0 a 19 años (4,2% del total de enfermos). El 52,4% fue en el grupo de 10 a 19 años...

Background. Cervical ectopic pregnancy is the implantation of the embryo in the lining of ​​the endocervical canal lining. It represents less than 1% of all ectopic pregnancies. Case description: We report two patients who come to the emergency room for transvaginal bleeding. The diagnosis of cervical ectopic pregnancy was made by transvaginal ultrasound (7- and 8-weeks' gestation). Treatment was started with methotrexate (28-year-old patient) and methotrexate-folinic acid (35-year-old patient). Due to the increase in human chorionic gonadotropin hormone, it was decided to perform an abdominal hysterectomy (28-year-old patient) and McDonald-type cervical curettage-cerclage (35-year-old patient). There were no complications after surgery in both patients. Conclusions: The treatment of cervical ectopic pregnancy is controversial. The most appropriate therapy should be chosen to preserv...

Background: Kawasaki disease (KD) is an acute and self-limited vasculitis common in children under five years. The diagnosis is a challenge in children under six months of age. Report case: We report a three-month-old infant with fever and a painful neck tumor of three days of disease. He was diagnosed with an abscessed cervical mass and received antibiotic treatment for ten days. During hospitalization, macular erythematous lesions developed throughout the body, persistence of fever, and elevated inflammatory markers. Echocardiography was performed, finding dilatation of the coronary arteries, being diagnosed with incomplete KD. He received intravenous human immunoglobulin and acetylsalicylic acid. He is currently undergoing cardiology controls with acetylsalicylic acid due to persistent dilatation of the coronary arteries. Conclusions: Cervical adenitis can mimic other skin infections ...

Budd-Chiari syndrome is caused by an obstruction of blood flow to the liver. Published cases of the antiphospholipid syndrome associated with BCS are limited in the pediatric population. We report a 15-year-old adolescent who presented with fever, ascites, and hepatosplenomegaly. Hepatic Doppler ultrasound revealed no flow in the right and middle hepatic veins and in the inferior vena cava. Abdominal tomography revealed extensive thrombosis of the inferior vena cava. During hospitalization, she was diagnosed with antiphospholipid syndrome and systemic lupus erythematosus. She was given treatment with unfractionated heparin, low molecular weight heparin, and anticoagulants. Budd-Chiari syndrome secondary to the antiphospholipid syndrome is a life-threatening disease. Timely diagnosis and treatment improve the quality of life of the patient.

Objective. To estimate the mortality attributable to diabetes mellitus (DM) as recorded by Peru’s Ministry of Health and its association with the human development index (HDI). Methods. This was an ecological study based on a secondary analysis of death records belonging to the Ministry of Health for the period from 2005 to 2014. A death was considered attributable to DM if the underlying cause of death given in the death record was DM. Mortality attributable to DM has been presented descriptively and in terms of geospatial analyses, and Spearman’s rho was used to test for an association between the difference in the mortality attributable to DM (between 2005-2006 and 2013-2014) and the HDI in Peru’s various departments.

Incontinentia pigmenti es una rara genodermatosis ligada al cromosoma X caracterizada por lesiones ampollares distribuidas sobre las líneas de Blaschko. Esta se presenta en cuatro estadios: vesicular, verrugoso, hiperpigmentado y atrófico. Es más frecuente en mujeres por su letalidad en varones, aunque hay casos de sobrevivencia en ellos. Se presenta el caso de un varón de 30 días de nacido que presentó lesiones vesiculo-ampollares de distribución lineal siguiendo las líneas de Blaschko. Se le realizó una biopsia cutánea cuya conclusión fue incontinentia pigmenti en estadio vesicular. Este es el primer caso varón reportado en la literatura peruana.

Objetivos: Determinar la tasa de publicación de las tesis de pregrado de Medicina Humana de una Universidad estatal de Cusco (Perú), en revistas científicas indizadas, así como las características y el impacto de estas publicaciones. Material y métodos: Se realizó un estudio retrospectivo; se recolectaron todas las tesis de pregrado de la universidad mencionada entre el 2000 y 2012, se determinó si fueron o no publicadas en alguna revista científica, mediante una búsqueda realizada en Google Académico, Lilacs, Lipecs, SciELO y Medline. Resultados: En el periodo de estudio se registraron 398 tesis de pregrado de Medicina Humana; fueron publicadas 20 (5,0%). Las bases de datos Lilacs (100,0%) y Lipecs (95,0%) fueron donde se encontraron la mayor cantidad de tesis. Solo una de las tesis fue publicada en una revista no peruana. Conclusiones: La tasa de publicación de las ...

Introduction: The incidence of thyroid cancer has increased worldwide. Peru has few reports describing the national and regional epidemiology of thyroid cancer. Objective: The incidence of thyroid cancer has increased worldwide. Peru has few reports describing the national and regional epidemiology of thyroid cancer. Methods: A descriptive study of trends was conducted with secondary data obtained from a public information source in Peru. The ICD 10: C73.0 coding record was evaluated, by age group, year and region. The age-standardized prevalence (period 2005 to 2016) and mortality (period 2005 to 2015) were calculated by region and year of study. Results: In the 2005-2016 period, 19 513 cases of thyroid cancer were recorded. The age group with the highest frequency was 30 to 59 years (57.7%). The prevalence increased from 4.7 to 15.2 cases per 100 000 inhabitants in the period 2005-2016...

El reordenamiento genético es la combinación de segmentos de genes que se produce por la cofluencia de algunos virus de la misma especie o virus, altera la infecciosidad y el grado de patogenicidad del virus.

OBJETIVO: Determinar los factores asociados a mortalidad en pacientes diabéticos tipo 2 hospitalizados en tres hospitales de la ciudad del Cusco, 2016. MATERIALES Y METODOS: Estudio de tipo casos y controles (17 casos y 34 controles por cada sede hospitalaria) realizado en los hospitales de la ciudad del Cusco (Hospital Regional del Cusco, Hospital Antonio Lorena y Hospital Adolfo Guevara Velasco) durante el año 2016. Se recolectó la información de las historias clínicas mediante una ficha de recolección de datos. Se realizó análisis descriptivo de las variables categóricas y numéricas; así como análisis bivariado entre los posibles factores asociados con la variable de interés “defunción”, para lo cual se calcularon los odds ratio (OR), con sus respectivos intervalos de confianza al 95%. Se consideraron significativos los valores p<0,05. RESULTADOS: De los 153 registro...

Job satisfaction is defined as a pleasurable or positive emotional state resulting from a subjective perception of the work experiences of the subject (1). Worker satisfaction in the performance of their duties plays a very important role in the quality of health care; therefore the measurement of job satisfaction is a necessary task. In Peru we have limited information on job satisfaction that presents health personnel in some areas experiencing armed conflict, one being the sector Kiteni Echarate district (adjacent to the VRAE - Valley of the Apurimac and Ene rivers) of the Province of the Convention in the region of Cusco (2).