Medicinal plants are becoming more important every day as alternatives to various diseases compared to chemical therapies. The present bibliographic review aims to identify the phytochemical characteristics of the phenolic compounds and phytopharmacological activities of Porophyllum ruderale, responsible for its nutritional properties and its anti-inflammatory, antileshmanial and antioxidant activity, for this we describe some phytochemical characteristics of Porophyllum ruderale that could be responsible of its medicinal properties. Despite there being limited scientific information on all the mechanisms of action and medicinal activities of Porophyllum ruderale, this review brings together a series of studies that report its anti-inflammatory, antileshmanial and antioxidant activity. In this way, through the bibliographic review, important information was collected on the phytochemical...

In patients undergoing dialysis, malnutrition is a very frequent characteristic, which is why oral nutritional supplementation administered to these patients can contribute to adequate protein intake and energy intake, thus improving protein anabolism. The objective of the present review was oriented to the bibliographic search of existing scientific articles on the nutritional contribution based on artificial enteral nutrition in patients with chronic renal disease submitted to dialysis which tends to increase morbidity and mortality in these patients, also different risk factors that are associated to malnutrition and future consequences in this type of patients are mentioned. Most of the customized formulas aimed at feeding patients with chronic kidney disease are of great help to the patient, providing proteins and nutrients vital to health, considering that these formulas could bene...

The bibliographycal review of indirect methods of assessment of adherence to therapeutic was performed, in order to publicize to health professional available strategies that can be helpful to achieve the effectiveness of prescribed treatment; whenever such methods are applicable in the clinical interview with patient in daily work, especially of physician.

Was the literature review of therapy by inhalation in the treatment of respiratory diseases; chronic obstructive puhnonary disease (COPD), asthma, chronic bronchopulmonary, with a growing interest in using it in other pathologies whose target organ is the lung infections. However, the precise medication in the proper use of inhalers, leam about disease and medication use to ensure effective treatment. The desire to enhance the proper use of the inhaler makes the patient more anxious and vulnerable for its improvement, the correct use of the inhaler reduces the possible adverse effects. Asthmatic patients, pharmaceutical care shows positive results in the quality of life of the patient. The Chemical Pharmaceutical is the ideal professional to perform pharmaceutical care to patients with asthma by his academic background and experience in care in community pharmacies.

Se realizó la revisión bibliográfica de los métodos indirectos de valoración del cumplimiento terapéutico, con la finalidad de dar a conocer al profesional de la salud las estrategias disponibles que pueden servir de ayuda para alcanzar la efectividad del tratamiento prescrito; toda vez que tales métodos son aplicables en la entrevista clínica al paciente en el quehacer cotidiano, sobretodo del médico.

Se realizó la revisión bibliográfica de la terapia por inhalación en el tratamiento de enfermedades respiratorias; enfermedad puhnonar obstructiva crónica (EPOC), asma, infecciones broncopulmonares crónicas, con un interés creciente por emplearla en otras patologías cuyo órgano diana es el pulmón. Sin embargo, la medicación precisa del manejo correcto de inhaladores, conocer la enfermedad y el medicamento a usar para asegurar el tratamiento efectivo. El deseo de mejorar el manejo correcto del inhalador hace al paciente más ansioso y vulnerable por lograr su mejoría, la utilización correcta del inhalador disminuye los posibles efectos adversos. La atención farmacéutica orientada a pacientes asmáticos, demuestra resultados positivos en la calidad de vida del paciente. El Químico Farmacéutico es el profesional idóneo para realizar la atención farmacéutica a pacientes a...

The aim of this studio was explore the antioxidant, anti-inflammatory anti-enzimatic potential of hydro-alcoholic extract of Caesalpinia spinosa "tara" pods. The antioxidant activity was determined by neutralization of radical 1,1-diphenyl-2-picryl-hidrazilo (DPPH•+) and 2,2'-azinobis acid (3-ethylbenzothiazoline)-6-sulfonic acid (ABTS•+). The antienzymatic activity was assessed by inhibition of the enzymes collagenase and elastase. The antiinflammatory activity was determined by the method of induction of plantar edema in rats λ-carrageenan. 30 albino rats Holtzman strain were used, with average weight 200 ± 20g, randomly distributed in five groups of six, a control with saline, a group with indomethacin pharmacological standard and intervention groups with alcoholic extract doses of 50, 100 and 250 mg/kg, respectively. The extract showed antioxidant activity in DPPH (EC50 = 4,52 ...

Se tuvo como objetivo explorar los potenciales antioxidante, antienzimático y antiinflamatorio del extracto hidroalcohólico de vainas de Caesalpinia spinosa “tara”. La actividad antioxidante se determinó por neutralización de los radicales 1,1-difenil-2-picril-hidrazilo (DPPH•+) y del ácido 2,2’-azinobis (3-etilbenzotiazolin)-6-sulfónico (ABTS•+). La actividad antienzimática se evaluó por inhibición de las enzimas colagenasa y elastasa. La actividad antiinflamatoria se determinó por el método de inducción de edema plantar en ratas por λ-carragenina. Se emplearon 30 ratas albinas de cepa Holtzman, con peso promedio de 200 ± 20 g, distribuidas al azar en cinco grupos de seis, un control con suero fisiológico, un grupo con el estándar farmacológico indometacina y los grupos de intervención con el extracto hidroalcohólico en dosis de 50, 100 y 250 mg/kg, respecti...

Con el fin de evaluar el efecto que ejercen las semillas de chía (Salvia hispanica L.) sobre los niveles de glicemia postprandial en jóvenes estudiantes universitarias sanas, se propone un estudio experimental donde las participantes fueron 25 jóvenes universitarias sanas, de 19 a 26 años y sin antecedentes familiares de diabetes. En días distintos, se les administró por vía oral 50 g de glucosa diluida en agua de mesa (primera administración) y 50 g de glucosa con 30 g de chía (segunda administración), posteriormente, se midió la glucosa en sangre periférica a los 0, 30, 60, 90 y 120 minutos. Los resultados demostraron que la administración que incluyó las semillas de chía logró disminuir de manera significativa la curva de glicemia postprandial en comparación con el control con glucosa, especialmente en los minutos 60, 90 y 120. El área bajo la curva glicémica que in...

Maca (Lipidium meyenii Walp,) is a Peruvian product with different properties and health benefits, however, depending on its nature both in its processed state and as a raw material, it can present polluting substances from its natural appearance or state of conservation. The objective of the study was to detect mycotoxigenic molds and identify heavy metals of lead and mercury in maca flour from the Buenos Aires agricultural market in the Carhuamayo District, Huancayo Province and Junín Department. The detection of molds was made by the direct method, appreciating species of the genus Cephalosporium sp. (HMD1) and Penicillium sp. (HMD2) and by the indirect method a dilution (-7) 5x108 cfu / mL of yeast was obtained. In the identification of heavy metals by atomic absorption spectrophotometry, the presence of lead was evidenced in 0.17 mg / kg average amount at the toxic value of the per...

This study aimed to characterize the chemical components of essential oil of Citrus sinensis L., determine its antibacterial activity and make dosageforms, mainly for local use. The essential oil was obtained from the dried leaves of the selected species, using a hydrodistillation system with water steam sweep; tests were conducted miscibility and determination of physical constants, such as specific gravity, refractive index and optical rotation. The chemical composition was determined by Gas Chromatography/Mass Spectrometry (CG/EM), standing out in the sugiero: chromatogram spectral signals in the elucidating: Limonene, beta-linalool, decanal and 2 (10)-pinene(1S,5S)-(-)-. The determination of antibacterial activity in vitro was tested by agar diffusion method and the formation of inhibition halos against strains of Gram (+), as Staphylococcus aureus ATCC 25,933 and Staphylococcus epid...

This study aimed to characterize the chemical components of essential oil of Citrus sinensis L., determine its antibacterial activity and make dosageforms, mainly for local use. The essential oil was obtained from the dried leaves of the selected species, using a hydrodistillation system with water steam sweep; tests were conducted miscibility and determination of physical constants, such as specific gravity, refractive index and optical rotation. The chemical composition was determined by Gas Chromatography/Mass Spectrometry (CG/EM), standing out in the sugiero: chromatogram spectral signals in the elucidating: Limonene, beta-linalool, decanal and 2 (10)-pinene(1S,5S)-(-)-. The determination of antibacterial activity in vitro was tested by agar diffusion method and the formation of inhibition halos against strains of Gram (+), as Staphylococcus aureus ATCC 25,933 and Staphylococcus epid...

The aim of the study was to evaluate the antioxidant and antiphotoaging effects of extracts of brown alga Macrocystis integrifolia Bory and develop a dermocosmetic form. From this extracts, was designed the dermocosmetic form in concentrations of 1, 3 and 5%, on a base made of lard with incorporation of beeswax and sesame oil to a pH of 6,5. The antioxidant activity was determined by in vitro methods as CDP and ABTS. The evaluation of antiphotoaging effect in vivo was performed using 25 albino female mice of Mus musculus specie, strain Bald / C53, who were divided into five groups of five mice each; except the group that served as blank, control and intervention groups were depilated hair back and subjected to UVB irradiation for 7 days, morning and night. The in vitro antioxidant activity assay showed that between extracts from stem, foliage and bulb of this alga, there are differences ...

El objetivo del estudio fue evaluar el efecto antioxidante y antifotoenvejecimiento de extractos de la alga parda Macrocystis integrifolia Bory y elaborar una forma dermocosmética. Obtenidos los extractos, se diseñó una forma dermocosmética en concentraciones de 1, 3 y 5%, elaboradas sobre una base de manteca de cerdo con incorporación de cera de abejas y aceite de sésamo a un pH de 6,5. La actividad antioxidante in vitro se determinó por lo métodos CDP y ABTS. La evaluación del efecto antifotoenvejecimiento in vivo se realizó empleando 25 ratones albinos hembra de la especie Mus musculus, cepa Bald/C53, que fueron distribuidos en cinco grupos de cinco ratones cada uno; a excepción del grupo que sirvió de blanco, el grupo control y los grupos de intervención fueron depilados en el lomo y se sometieron a la irradiación UVB durante 7 días, mañana y noche. El ensayo in vitro...

Objective of the study was to compare the sunscreen effect in vivo of a cream made with the hydroalcoholic extract of the brown seaweed Macrocystis pyrifera (Linnapus) Agardh, with comercial sunscreens in skin lesions prevention. The biological sample was collected in the continental socket from Yanyarina beach, San Juan de Marcona, Ica region. Hydroalcoholic extract (ethanol 1:1) was obtained for maceration process since 300 g seaweed. With the extract was formulated and design the blocker dermocosmetic using concentrations of 5, 10, and 15%, respectively, with a mixture of solids aliphatic alcohols, consisting mainly of Cetyl alcohol (C16H3O) and Stearyl alcohol (C18H39O) 50/70%. Were used albino mice, mus musculus specie, bald c53 strain, adult males, with average weight 30 g. Photoprotective potential in vivo was tested through topical application on mice skin, in the dorsal anterior...

El estudio tuvo como objetivo comparar el efecto fotoprotector in vivo de una crema elaborada con el extracto hidroalcohólico de la macroalga parda Macrocystis pyrifera (Linnapus) Agardh frente a bloqueadores solares comerciales en la prevención de lesiones de piel. La muestra biológica fue colectada en el zócalo continental de la playa Yanyarina de San Juan de Marcona de la región Ica. El extracto hidroalcohólico (etanol-agua 1:1) se obtuvo por proceso de maceración a partir de 300 g de alga. Con el extracto se formuló y diseño el bloqueador dermocosmético empleando concentraciones 5, 10 y 15%, respectivamente, con una mezcla de alcoholes alifáticos sólidos, conformados principalmente por alcohol cetílico (C16H3O) y alcohol estearílico (C18H39O) 50/70%. Se emplearon 35 ratones albinos adultos machos de la especie Mus musculus cepa Bald C53 de peso promedio 30g. El potencia...

Was determinated chemical composition of essential oil from Caesalpinia spinosa, obtained by stripping with steam method, with a yield of 0,125% v/w, as well as its antioxidant capacity and antibacterial effect against Streptococcus mutans ATCC 35668. To identify chemical constituents were employed Gas Chromatography and Mass Spectrometry (GC/MS), finding 23 compounds, being in greater quantity: pelargonaldehído (11,21%); dihydro-neoclovene-(i) (5,51%); naphthalene,1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-,(15-CIS)- (4,87%) y dihydro-cis-alfa-copaene-8-ol (4,13%). Evaluation of antioxidant activity was performed using the methods of 2,2-diphenyl-1-picrylhydrazyl (DPPH) and acid radical 2,2'-azino-bis- (3-etilbenzotiazolin-6-sulfonic acid) (ABTS—⁺), determining that IC50 to both methods was > 200 µL/mL, using as captation reference trolox®, which had IC50 3,8 µg/mL....

Se determinó la composición química del aceite esencial de Caesalpinia spinosa, obtenido por el método de destilación por arrastre con vapor de agua con un rendimiento de 0,125% v/p, así como su capacidad antioxidante y actividad antibacteriana frente a Streptococcus mutans ATCC 35668. Para la identificación de los constituyentes químicos se emplearon Cromatografía de Gas y Espectrometría de Masas (CG/EM), encontrándose 23 compuestos, de los cuales destacan en mayor porcentaje: pelargonaldehído (11,21%); dihydro-neoclovene-(i) (5,51%); naphthalene,1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-(1-methylethyl)-,(15-CIS)- (4,87%) y dihydro-cis-alfa-copaene-8-ol (4,13%). La evaluación de la actividad antioxidante se realizó aplicando los métodos de 2,2–difenil-1-picrilhidracilo (DPPH) y del radical ácido 2,2’-azino-bis-(3-etilbenzotiazolin-6-sulfónico) (ABTS—⁺), determinándo...