La investigación se realizó en la institución educativa Túpac Amaru distrito de Pomacanchi, provincia de Acomayo, Cusco - 2019. El objetivo del estudio fue: Establecer la relación existente entre hábitos y técnicas de estudio y el rendimiento escolar en los estudiantes del 6º grado de educación primaria en la institución educativa Túpac Amaru distrito de Pomacanchi, provincia de Acomayo, Cusco - 2019. Siendo la hipótesis que se sustentó la siguiente: Existe relación entre hábitos de estudio y rendimiento escolar en los estudiantes de educación primaria en la institución educativa Túpac Amaru distrito de Pomacanchi, provincia de Acomayo, Cusco - 2019. El tipo de estudio es descriptivo correlacional se efectúa cuando se desea establecer una relación de dependencia entre la variable independiente y dependiente, y su diseño es no experimental. La muestra está constituid...

Objetives: To determine the gastroprotector effect of Copaifera officinalis oil using indomethacin and pyloric ligature in rats. Design: Preclinical study. Setting: Faculties of Medicine, Pharmacy and Biochemistry, National University of San Marcos, Lima, Peru. Biological material: Rats and copaiba oil. Interventions: Copaiba oil was collected in Ucayali, Pucallpa. Cytoprotection was tested with indomethacin considering a normal control group, and indomethacin, copaiba and omeprazole groups. Using visual analogue scale mucosa gastric injuries were referred as those compatible with local necrosis (unviable tissue), hyperemia, flushing, and hemorrhage, and ulcers according to the modified Macallister’s scale. The anti-secretion trial used the pyloric ligature model. Twenty-four albino rats were randomized in three groups: control, copaiba oil 40 mg/kg and omeprazole 10 mg/kg, respectivel...

Objectives: To determine the protective effect of Piper aduncum (matico) leaves ethanol extract and its phytomedicine in capsules in liver cirrhosis induced in rats. Design: Experimental. Location: Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru. Biological material: Leaves of Piper aduncum, and Rattus norvegicus, Holtzman strain. Interventions: The leaves were collected in La Merced district, Pasco department. The phytomedicine capsules were prepared from the plant ethanol extract. Cirrhosis was induced with phenobarbital 0.5 mg/mL diluted in drinking water during 15 days, then carbon tetrachloride 0.2mL/kg 1:1 in olive oil orally during 7 days. Blood samples were drawn in order to determine liver profile and malondialdehyde; the animals were sacrificed, extracting the liver for pathology study. Data were evaluated by multivariate techniques with p <0.05. Ma...

Objective: To determine efficacy and security of of Annona muricata L (guanábana) leaves ethanolic extract plus glibenclamide capsules in controlling glucose levels in type 2 diabetes mellitus patients compared to patients receiving with glibenclamide alone. Design: Randomized, double-blind, parallel-group controlled clinical trial. Setting: Internal Medicine service, Tingo María-EsSalud Hospital I, Huanuco city. Par ticipants: Type 2 diabetes mellitus patients. Interventions: Between May 2007 and September 2007 sixty 38 to 60 year-old patients were randomly assigned to 6 groups, 3 receiving capsules containing 180 mg of Annona muricata L leaves ethanolic extract plus glibenclamide 5 mg and 3 receiving glibenclamide 5 mg tablets only. Main outcome measurements: Reduction of glycemia. Results: There was reduction of glycemic levels, higher in those receiving guanabana plus glibenclamida...

Estudio clínico, aleatorio, grupo paralelo, doble ciego, realizado en el Servicio de Medicina Interna del Hospital I Tingo María, de EsSalud, en el Departamento de Huánuco, para determinar la eficacia y seguridad de cápsulas de extracto etanólico de hojas de Annona muricata L (guanábana) más glibenclamida, para un mejor control de los niveles de glicemia comparado con la administración de glibenclamida sola, en pacientes con diabetes mellitus tipo 2. Entre mayo y setiembre de 2007, 60 pacientes fueron asignados a 6 grupos de manera aleatoria; 3 grupos recibieron cápsulas conteniendo 180 mg de extracto etanólico de hojas de Annona muricata L. más 5 mg de glibenclamida, los otros 3 grupos continuaron solo con glibenclamida, y se evaluaron los niveles de glicemia. Se encontró disminución del nivel de glicemia, siendo mayor el efecto en aquellos que recibieron guanábana más gl...