Evalúa los compuestos bioactivos, la actividad inhibitoria hialuronidasa y la capacidad antioxidante de la fruta Pourouma. cecropiifolia. Las frutas fueron recolectadas en Puerto Maldonado y clasificadas taxonómicamente en el Museo de Historia Natural. El extracto metanol/agua de la fruta fue liofilizado, este se denominó extracto de uvilla (EU) y este constituyó la unidad experimental. Los compuestos bioactivos del EU como el contenido total de polifenoles (CPT), contenido de flavonoides totales (CFT), antocianinas (ANT) y ácido ascórbico (AA) fueron analizados por espectrofotometría. Se utilizaron tres pruebas in vitro para medir la capacidad antioxidante: poder reductor, capacidad de captación del radical DPPH y capacidad de captación del radical ABTS. La técnica HPLC y HPLC/EM/EM se llevo a cabo para evaluar el perfil de polifenoles e identificar los compuestos. El comporta...

Describe algunas pautas sobre la investigación en plantas medicinales, para lograr su uso adecuado con el debido sustento científico. Por ello, el estudio comprende: 1) la caracterización fotoquímica; 2) el estudio de las especificaciones de la calidad del extracto; 3) el aislamiento y elucidación estructural del principio activo; 4) las especificaciones del fitomedicamento. En la Facultad de Odontología se han realizado varios trabajos de tesis sobre plantas medicinales; entre estas se menciona a la Tabebuia serratifolia, en la cual se comprobó la actividad antibacteriana del extracto de la corteza sobre Streptococcus mutans. En otra investigación se demuestra que el aceite esencial de Minthostachys mollis (muña) presentaba actividad antibacteriana frente a bacterias orales. Las especies Plantago major L y Citrus paradisi, presentes en una pasta tópica, resultaron ser efectiva...

The seed and peel of the Passiflora tripartita fruit, have compounds of great importance that could be used by the agroindustry, pharmaceutical industry and medicine. This review article collects information on phenolic compounds, dietary fibers, and essential oils that fruit fractions have. The pulp of this fruit is intended for the preparation of antioxidant and additive functional beverages. The reports mention that the seeds have a high amount of polyunsaturated fatty acids, phenolic, and terpenes, and suggest being used in the form of nanoemulsions and as antimicrobials. Also, the terpenes in the essential oil of the seed have been linked to the treatment of colon cancer. Regarding the use of the peel, many species of the same genus are investigated for their antioxidant capacity, pectin content, dietary fiber and antimicrobial activity, having potential uses as antioxidant additive...

“Pitahaya amarilla” (Hylocereus megalanthus) and “tumbo serrano” (Passiflora tripartita var. mollisima) two fruits that grow in Peru. The aim of this study was to evaluate the hypoglycemic activity by in vitro inhibition of α-amylase and α-glucosidase enzymes. The fruits were pulped and lyophilized, and after the obtaining of aqueous extracts, the total phenolic content (TPC) was determined by the Folin-Ciocalteu method. Inhibitory activity was determined by IC50, and the type of inhibition was evaluated using 0,25-2 mg/mL and 0,02-0,28 mg/mL of the extract of tumbo serrano for α-amylase and α-glucosidase, respectively. For pitahaya amarilla, 4-64 mg/mL and 0,8-25,6 mg/mL were used for each enzyme, respectively. The TPC for the tumbo serrano and pitahaya amarilla were 614,67 and 16,17 mg/100 g of sample, respectively, expressed as gallic acid equivalents. The aqueous extract ...

The objective of the present study was to evaluate the extraction and microencapsulation of antioxidant compounds from Oenocarpus bataua Mart seed, commonly known as “ungurahui” or “patawa”. The extraction process was performed in an ultrasonic bath and the orthogonal composite central design of the response surface methodology (RSM) was used to determine the optimal extraction conditions, using two factors: ethanol concentration (48.44 to 91.56%) and extraction time (13.83 to 46.17 min). The optimal extraction conditions (48.44% ethanol and 13.83 min) allowed to obtain the extract (EUL) with the highest number of antioxidants (yield (YI): 24.64%, total phenolic content (TPC): 452.76 mg GAE/g EUL and DPPH: 74.26%). Microencapsulation of EUL with maltodextrin by spray drying produced microcapsules (EUM) of homogeneous size (5 µm), without cracks or fissures and that preserved its...

The objective of the present study was to evaluate the extraction and microencapsulation of antioxidant compounds from Oenocarpus bataua Mart seed, commonly known as “ungurahui” or “patawa”. The extraction process was performed in an ultrasonic bath and the orthogonal composite central design of the response surface methodology (RSM) was used to determine the optimal extraction conditions, using two factors: ethanol concentration (48.44 to 91.56%) and extraction time (13.83 to 46.17 min). The optimal extraction conditions (48.44% ethanol and 13.83 min) allowed to obtain the extract (EUL) with the highest number of antioxidants (yield (YI): 24.64%, total phenolic content (TPC): 452.76 mg GAE/g EUL and DPPH: 74.26%). Microencapsulation of EUL with maltodextrin by spray drying produced microcapsules (EUM) of homogeneous size (5 µm), without cracks or fissures and that preserved its...

The aguaymanto is a native species of the Peruvian highland, which has a tiny fruit that disagrees with its greatness and nutritional therapy. The present investigation had as objetive to assess and compare the total polyphenol content by the Folin-Ciocalteu method and antioxidant capacity of the fruits of Physalis peruviana L., from Huánuco, Junín, Ancash y Cajamarca by the method of the DPPH (1,1-diphenyl-2-picril-hidrazilo). The fruit coming from Huánuco presented a higher content of phenolic compounds expressed as 149.3 ± 1.62 mg/Eq of gallic acid/100g fruit. In addition, greater antioxidant capacity obtaining as inhibitory concentration IC50 1.86 mg/mL, compared with the fruits from Junín, Ancash y Cajamarca; and it would be a good source of consumption in benefit for the health.

El fruto del Vaccinium floribundum Kunth “pushgay”, integra al grupo de los berries nativos, el cual presenta una gran cantidad de antioxidantes, mucho mayor que los arándanos que actualmente se exportan a diferentes países. El objetivo de este estudio fue la determinación de los parámetros fisicoquímicos y la capacidad antioxidante in vitro del extracto vegetal del Vaccinium floribundum Kunth. Se prepararon extractos por maceración a partir de frutos liofilizados, usando como solvente etanol al 50 %, 70 % y 96 %. Los extractos presentaron valores similares de densidad relativa, sólidos totales, índice de refracción, grados Brix y pH. El tamizaje fitoquímico evidenció la presencia de carbohidratos, azúcares reductores, taninos, compuestos amino y heterósidos, destacando los compuestos fenólicos y flavonoides de relevante capacidad antioxidante. El extracto al 50 % prese...