The efficacy of benzalkonium chloride for the treatment of dermatomicosis caused by Trichophyton sp. in guinea pig (Cavia cobayo) was evaluated in 200 guinea pigs of two months old, that showed typical clinical signs of dermatomicosis. Hair samples and skin grudges were taken for direct exam and for in vitro culture in Dermatophytes Test Medium and Mycobiotic. Skin biopsies for pathobiology were prepared. The guinea pig were divided in groups A and B of 100 animals each. Group A was treated with 0.1% aqueous benzalkonium chloride solution, whereas group B was treated with water as placebo. All samples were positive to media culture by 3rd to 7th day and Trichophyton mentagrophytes was isolated. Sixty percent of the samples were positive to direct exam. Histological study showed mild hyperkeratosis. Healing of lesions and hair growth were observed in all treated guinea pigs by the end of ...

The aim of this study was to generate calibration equations to predict the nutritional chemical composition of the Italian rye grass (RG) (Lolium multiflorum Lam) by near infrared spectroscopy (NIRS). A total of 75 samples of RG of different harvesting weeks were collected from the IVITA Research Center in Huancayo (Peru). Spectrum capture was performed using NIRS and the chemical analysis was done for reference of the following components: crude protein (CP), ether extract (EE), total ash (CZ), crude fibre (CF) and neutral detergent fibre (NDF). A calibration and validation model by partial least squares (PLS) was developed and the correlation coefficient (R), coefficient of determination (R2), root mean square error of calibration (RMSEC), root mean square error of prediction (RMSEP), ratio range with error (RER) and residual predictive deviation (RPD) were used as statistics of accura...

Se evaluó la eficacia del cloruro de benzalconio en el tratamiento de la dermatomicosis causada por Trichophyton sp. en el cuy (Cavia cobayo). Se utilizó 200 cuyes de 2 meses de edad que presentaban signos clínicos de dermatomicosis. Los cuyes fueron divididos al azar en dos grupos (A y B) similares. Al grupo A se le aplicó una solución acuosa de cloruro de benzalconio al 0.1% como único tratamiento y en el grupo B se empleó agua como placebo. Previo al tratamiento, se tomaron muestras de pelos y escamas de piel para examen directo y cultivo en los medios Dermatophytes Test Medium (DTM) y Mycobiotic, así como biopsias de piel para estudio histológico. Todas las muestras resultaron positivas a hongos entre el 3º y 7º día, tipificándose la especie Trichophyton mentagrophytes con la ayuda de microcultivos y lectura en agar urea. El 60% de las muestras fueron positivas al examen...

The aim of this study was to generate calibration equations to predict the nutritional chemical composition of the Italian rye grass (RG) (Lolium multiflorum Lam) by near infrared spectroscopy (NIRS). A total of 75 samples of RG of different harvesting weeks were collected from the IVITA Research Center in Huancayo (Peru). Spectrum capture was performed using NIRS and the chemical analysis was done for reference of the following components: crude protein (CP), ether extract (EE), total ash (CZ), crude fibre (CF) and neutral detergent fibre (NDF). A calibration and validation model by partial least squares (PLS) was developed and the correlation coefficient (R), coefficient of determination (R2), root mean square error of calibration (RMSEC), root mean square error of prediction (RMSEP), ratio range with error (RER) and residual predictive deviation (RPD) were used as statistics of accura...

5 páginas

The ulcerogénic capacity as a single oral dose of three nonsteroidal anti·inflammatory drugs (NSAIDs) of ample use in Therapeutic as they are celecoxib, ibuprofeno and indometacina was evaluated. Eight (08) male rats were dis tributed in four groups. Animals fasting during 24h previous to experiment. Group 1: lndomethacin was administrated 15 mg/kg oral dose. Group 2: Ibuprofen 100 mg/kg oral dose. Group 3: Celecoxib 100mg/kg/oral dose. Group4: physiological serum (Control). Macroscopic evaluation of small intestine (jejunum-ileum) were carried out at first day after drug administration. Intestinal injury were observed a long the mesenteric si de of the middle and distal jejunum. Macroscopic lesions consisted of bowel thickening and dilatatíon, absence of the mucosa, hyperemia and multiple round ulcers. The treatment with celecoxib was the one that displayed minor damage. The greater ...

The ulcerogénic capacity as a single oral dose of three nonsteroidal anti·inflammatory drugs (NSAIDs) of ample use in Therapeutic as they are celecoxib, ibuprofeno and indometacina was evaluated. Eight (08) male rats were dis tributed in four groups. Animals fasting during 24h previous to experiment. Group 1: lndomethacin was administrated 15 mg/kg oral dose. Group 2: Ibuprofen 100 mg/kg oral dose. Group 3: Celecoxib 100mg/kg/oral dose. Group4: physiological serum (Control). Macroscopic evaluation of small intestine (jejunum-ileum) were carried out at first day after drug administration. Intestinal injury were observed a long the mesenteric si de of the middle and distal jejunum. Macroscopic lesions consisted of bowel thickening and dilatatíon, absence of the mucosa, hyperemia and multiple round ulcers. The treatment with celecoxib was the one that displayed minor damage. The greater ...

The objective was to determine the effect of Salmonella Typhimurium on the chemical composition and microbiological quality of the meat of guinea pig (Cavia porcellus). 30 male guinea pigs for fattening were used that were distributed in 3 treatments with ten (10) repetitions each; T1: mixed feeding + saline solution (control), T2: mixed feeding and experimentally challenged with Salmonella Typhimurium, T3: mixed feeding + APC (antibiotic growth promoter) and experimentally challenged with Salmonella Typhimurium. T1 animals were dosed orally with saline solution, while T2 and T3 were challenged with an infective dose (2 x 106 CFU) of Salmonella Typhimurium, only once on the 11th day of the start of the experiment. Despite manifesting the disease in animals challenged with Salmonella, they did not show differences (p <0.05) in the concentration of protein and ethereal extract on a dry ...

The effect of Salmonella Typhimurium was determined on the productive parameters of guinea pigs (Cavia porcellus). Forty recently weaned male guinea pigs fed with a base diet were used. The animals were distributed in four treatments with 10 repetitions each were used. T1: saline solution (control); T2: saline + AGP (antibiotic growth promoter antibiotic); T3: challenge with Salmonella Typhimurium; T4: challenge with Salmonella Typhimurium + AGP. Dosing with saline or with an infective dose of Salmonella Typhimurium (2 x 106 CFU) was made on day 11 of the study. Bodyweight gain, feed consumption, feed conversion, carcass yield and economic gain were evaluated. Samples were taken from organs and meat after the slaughtering for the microbiological analysis. Animals challenged with Salmonella (T3 and T4) showed lower bodyweight gain, higher feed intake and poorer feed conversion compared to...

The effect of Salmonella Typhimurium was determined on the productive parameters of guinea pigs (Cavia porcellus). Forty recently weaned male guinea pigs fed with a base diet were used. The animals were distributed in four treatments with 10 repetitions each were used. T1: saline solution (control); T2: saline + AGP (antibiotic growth promoter antibiotic); T3: challenge with Salmonella Typhimurium; T4: challenge with Salmonella Typhimurium + AGP. Dosing with saline or with an infective dose of Salmonella Typhimurium (2 x 106 CFU) was made on day 11 of the study. Bodyweight gain, feed consumption, feed conversion, carcass yield and economic gain were evaluated. Samples were taken from organs and meat after the slaughtering for the microbiological analysis. Animals challenged with Salmonella (T3 and T4) showed lower bodyweight gain, higher feed intake and poorer feed conversion compared to...

The aim of the study was to determine the productive parameters of guinea pigs raised with diets supplemented with fish oil and sacha inchi seeds. Forty eight male guinea pigs of 42 days old were used, with an initial body weight of 615 g. The guinea pigs were randomly assigned to 4 treatments with 3 repetitions (rearing pools) of 4 animals each. Dietary treatments were: T0: Control, T1: diet supplemented with 1.0% fish oil; T2: diet supplemented with 4.0% sacha inchi seed; and T3: diet supplemented with 1.0% fish oil + 4.0% sacha inchi seed. The experimental phase lasted 28 days. Body weight gain, feed intake, feed conversion and carcass yield were evaluated. The average of individual body weight gain ranged between 315 and 353 g per treatment, consumption ranged between 1172 and 1224 g dry matter, feed conversion ranged between 3.53 and 3.73 and carcass yield varied between 69.4 and 71...

The aim of the study was to determine the productive parameters of guinea pigs raised with diets supplemented with fish oil and sacha inchi seeds. Forty eight male guinea pigs of 42 days old were used, with an initial body weight of 615 g. The guinea pigs were randomly assigned to 4 treatments with 3 repetitions (rearing pools) of 4 animals each. Dietary treatments were: T0: Control, T1: diet supplemented with 1.0% fish oil; T2: diet supplemented with 4.0% sacha inchi seed; and T3: diet supplemented with 1.0% fish oil + 4.0% sacha inchi seed. The experimental phase lasted 28 days. Body weight gain, feed intake, feed conversion and carcass yield were evaluated. The average of individual body weight gain ranged between 315 and 353 g per treatment, consumption ranged between 1172 and 1224 g dry matter, feed conversion ranged between 3.53 and 3.73 and carcass yield varied between 69.4 and 71...

The present study evaluated the effect of the inclusion of probiotic, prebiotic and the combination of both (symbiotic) in the diet on the productive parameters of guinea pigs (Cavia porcellus). Fifty 3-day-old male guinea pigs were selected from a Prolific-Dairy maternal line developed in the IVITA-El Mantaro Research Station (Peru) and randomly distributed in five treatments consisting of a basal diet of forages (rye-grass and red clover). supplemented with wheat bran (T5), plus probiotic (T1), prebiotic (T2), symbiotic (T3) and antibiotic growth-promoter (AGP) (T4). The probiotic was a mixture of six bacterial species isolated from the intestine and guinea pig faeces; the prebiotic was a commercial mannanoligosaccharide and the APC was Zn-bacitracin. The response to treatments was evaluated for 56 days in terms of body weight gain, feed intake and feed conversion ratio. No significant...

The aim of this study was to evaluate the effect of dietary supplementation with sodium butyrate (BS) on productive performance in fattening guinea pigs. Fifty 14-21 days old weaned male guinea pigs were randomly distributed in five treatments (0, 100, 200, 300 ppm of BS, 200 ppm of Zn-Bacitracin). Body weight gain, feed consumption and feed conversion were evaluated 70 days after supplementation. No response patterns were detected due to BS or Zn-Bacitracin treatments. It is concluded that, under the experimental conditions, supplementation with BS did not improve the productive parameters evaluated.

The aim of this study was to determine the applicability of near infrared spectroscopy (NIRS) for the nutritional assessment of two important forage species in the country: alfalfa (Medicago sativa L) and red clover (Trifolium pratense L). For this, 75 samples of alfalfa varieties (SW 8210, WL 625HQ) and 75 of red clover varieties (Quiñequeli, Kendland) obtained from the paddocks of the IVITA El Mantaro Experimental Station, Junín region, Peru were used. Proximal analysis was performed determining the content of crude protein (CP), ether extract (EE), crude fibre (CF), total ash (TA) and neutral detergent fibre (NDF), and the spectrum was captured using NIRS equipment. The calibration and validation models were developed to estimate the predictive capacity using Partial Least Squares (PLS), and the accuracy and precision statistics used were the Correlation Coefficient (R), Determinati...

The present study evaluated the effect of the inclusion of probiotic, prebiotic and the combination of both (symbiotic) in the diet on the productive parameters of guinea pigs (Cavia porcellus). Fifty 3-day-old male guinea pigs were selected from a Prolific-Dairy maternal line developed in the IVITA-El Mantaro Research Station (Peru) and randomly distributed in five treatments consisting of a basal diet of forages (rye-grass and red clover). supplemented with wheat bran (T5), plus probiotic (T1), prebiotic (T2), symbiotic (T3) and antibiotic growth-promoter (AGP) (T4). The probiotic was a mixture of six bacterial species isolated from the intestine and guinea pig faeces; the prebiotic was a commercial mannanoligosaccharide and the APC was Zn-bacitracin. The response to treatments was evaluated for 56 days in terms of body weight gain, feed intake and feed conversion ratio. No significant...

The aim of this study was to evaluate the effect of dietary supplementation with sodium butyrate (BS) on productive performance in fattening guinea pigs. Fifty 14-21 days old weaned male guinea pigs were randomly distributed in five treatments (0, 100, 200, 300 ppm of BS, 200 ppm of Zn-Bacitracin). Body weight gain, feed consumption and feed conversion were evaluated 70 days after supplementation. No response patterns were detected due to BS or Zn-Bacitracin treatments. It is concluded that, under the experimental conditions, supplementation with BS did not improve the productive parameters evaluated.

The aim of this study was to determine the applicability of near infrared spectroscopy (NIRS) for the nutritional assessment of two important forage species in the country: alfalfa (Medicago sativa L) and red clover (Trifolium pratense L). For this, 75 samples of alfalfa varieties (SW 8210, WL 625HQ) and 75 of red clover varieties (Quiñequeli, Kendland) obtained from the paddocks of the IVITA El Mantaro Experimental Station, Junín region, Peru were used. Proximal analysis was performed determining the content of crude protein (CP), ether extract (EE), crude fibre (CF), total ash (TA) and neutral detergent fibre (NDF), and the spectrum was captured using NIRS equipment. The calibration and validation models were developed to estimate the predictive capacity using Partial Least Squares (PLS), and the accuracy and precision statistics used were the Correlation Coefficient (R), Determinati...

The present study evaluated the effect of supplementation with increasing levels of a liquid probiotic on the histomorphometry of the small intestine in guinea pigs. Fifty male guinea pigs were used from 3 days of age, distributed in a completely randomized design of five treatments with 10 repetitions each: 0, 1, 2 or 3 ml of probiotic or an antibiotic growth promoter (AGP, Zn-Bacitracin). Samples of duodenum, jejunum and ileum were taken from each animal at 84 days of age and the length and width of the intestinal villi, the depth of the Lieberkühn crypts and the length/depth relationship were measured. There were no consistent response patterns for most of the measurements in the three segments, except for a linear response (p=0.047) of the length/depth ratio in the duodenum and a positive effect (p=0.008) of the AGP over the length of villi in the ileum. It is concluded that, under ...

The present study evaluated the effect of supplementation with increasing levels of a liquid probiotic on the histomorphometry of the small intestine in guinea pigs. Fifty male guinea pigs were used from 3 days of age, distributed in a completely randomized design of five treatments with 10 repetitions each: 0, 1, 2 or 3 ml of probiotic or an antibiotic growth promoter (AGP, Zn-Bacitracin). Samples of duodenum, jejunum and ileum were taken from each animal at 84 days of age and the length and width of the intestinal villi, the depth of the Lieberkühn crypts and the length/depth relationship were measured. There were no consistent response patterns for most of the measurements in the three segments, except for a linear response (p=0.047) of the length/depth ratio in the duodenum and a positive effect (p=0.008) of the AGP over the length of villi in the ileum. It is concluded that, under ...