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1
artículo
Publicado 2024
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We present the case of a 44-year-old male patient with a family history of lymphoma and hyperthyroidism. He started the disease three months before admission to hospital with pain in the right leg, abdominal pain, weight loss and night sweats. He was diagnosed in his hospitalization with ascites in a cavity of undetermined etiology, and multiple polygastric and fossa lymph nodes right iliac. At 6 months, the symptoms persist and a nodule is added on the penis, left testicular edema and purulent discharge from the right inguinal node, being diagnosed orchiepididymitis. Initially he had negative markers for tuberculosis (TB), however, a lymph node biopsy was performed and the analysis with Xpert MTB/RIF where it resulted positive. The patient improved considerably with anti-TB treatment and antibiotics for purulent discharge.
2
artículo
Publicado 2010
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This is the case of a 33 years old man with history of homosexual relations and heavy alcohol drinking. Tobacco, marijuana, cocaine, basic paste and cocaine hydrochloride consumption since age 18. Because of human immunodeficiency virus infection he received irregular treatment (2006-2008) with highly active antiretroviral therapy (HAAT), regulated in the past 12 months. As the patient showed positive resistant acid-fast bacilli he received since June 2008 standard antituberculous treatment [2RHZE/4(HR)2)] (R: rifampicin; H: isoniazid; Z: pirazinamide; E: ethambutol) that was withdrawn 6 months later when the patient showed pulmonary negative acid fast bacilli. In March 2009 he felt intense lumbar pain, difficulty in walking, hypertrophy of cervical lymph nodes, cough and fever. Cervical lymph node discharge culture disclosed M. tuberculosis resistant to rifampicin. Imagenology showed se...
3
artículo
Publicado 2022
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Objetive: To describe a pediatric case with initial diagnosis of lymph node tuberculosis (TB) that became multidrug resistant miliar and meningeal tuberculosis (TB-MDR) due to treatment dropout twice. Case report: a 4-year-old boy with initial diagnosis of lymph node tuberculosis who had two episodes of dropout from the sensitive scheme treatment. Three months later, there was evidence of bilateral involvement suggestive of miliary TB. During hospitalization, he developed meningeal tuberculosis and hydrocephalus. Due to the history of treatment dropout, a sensitivity of gastric aspirate study was requested, identifying it as multidrug-resistant TB. He started the EZLfxKmEtoCs treatment scheme and complications management, achieving improvement. Conclusions: Treatment dropout is one of the main causes of drug resistance in tuberculosis and its complications. It is necessary to reinforce t...
4
artículo
Publicado 2025
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Tuberculosis affects one-third of the global population, with the highest incidence concentrated in developing countries and among immunosuppressed patients. Among its extrapulmonary manifestations, intestinal involvement ranks sixth in frequency, with a predilection for the ileocecal region, typically presenting as intestinal inflammatory changes and necrotic lymph nodes. The most common symptoms include abdominal pain, fever, and palpable mass, often associated with histological findings of confluent caseating granulomas and ulcerative mucosal lesions. Intestinal inflammatory processes can result from various etiologies. From an imaging perspective, it is essential to identify descriptors that help differentiate inflammatory-infectious conditions from neoplastic processes. Here, we present a case of intestinal tuberculosis with multifasic abdominopelvic computed tomography findings con...
5
artículo
Publicado 2013
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Tuberculosis and brucellosis remain important causes of morbidity and mortality in many countries, for the detection of both diseases requires efficient and sensitive tool for effectuate the diagnosis. This study was aimed to evaluate and compare the duplex PCR versus the nested PCR, for detection of Brucella spp. (BR) and Mycobacterium spp. (TB). A total of 100 samples of tissues from tracheo-bronchial lymph nodes, bovine lung and bacterial isolate as positive controls were used. Were evaluated ten combinations of primers which were designed to flank the segment of the 16S rRNA sequence (RB) and antigen gen MPB70 (TB), the best result for the Duplex PCR was obtained with the primers Bru-2F/Bru-2R for BR and Tub-1F/Tub-N-R for TB. The amplification of the products was 225 and 230-bp respectively. In order to compare the results of the proposed technique, all samples were initially analyz...
6
artículo
Publicado 2013
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Tuberculosis and brucellosis remain important causes of morbidity and mortality in many countries, for the detection of both diseases requires efficient and sensitive tool for effectuate the diagnosis. This study was aimed to evaluate and compare the duplex PCR versus the nested PCR, for detection of Brucella spp. (BR) and Mycobacterium spp. (TB). A total of 100 samples of tissues from tracheo-bronchial lymph nodes, bovine lung and bacterial isolate as positive controls were used. Were evaluated ten combinations of primers which were designed to flank the segment of the 16S rRNA sequence (RB) and antigen gen MPB70 (TB), the best result for the Duplex PCR was obtained with the primers Bru-2F/Bru-2R for BR and Tub-1F/Tub-N-R for TB. The amplification of the products was 225 and 230-bp respectively. In order to compare the results of the proposed technique, all samples were initially analyz...
7
artículo
Publicado 2024
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Introduction: enlargement of superficial lymph nodes is a frequent clinical finding which may be among the first evidences of a significant illness or of a specific clinical syndrome.Objective: exploring clinico-pathological relationships in patients consulting for the first time with a clinically detectable lymphadenopathy and no defined diagnosis.Materials and Methods: cross sectional prospective study including patients with clinically detectable lymphadenopathy (nodes over 1 cm in diameter) and often also suspicion of tuberculosis. Lymph node biopsies, fine needle aspirations, and other contributing diagnostic tests were performed. A histopathological classification was structured to arrange the information on the patients and to correlate laboratory findings with clinical ones.Results: patients recruited were 154; 55 (45.5%) out of 70 patients who had a tentative diag...
8
artículo
Publicado 2024
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Introduction: enlargement of superficial lymph nodes is a frequent clinical finding which may be among the first evidences of a significant illness or of a specific clinical syndrome.Objective: exploring clinico-pathological relationships in patients consulting for the first time with a clinically detectable lymphadenopathy and no defined diagnosis.Materials and Methods: cross sectional prospective study including patients with clinically detectable lymphadenopathy (nodes over 1 cm in diameter) and often also suspicion of tuberculosis. Lymph node biopsies, fine needle aspirations, and other contributing diagnostic tests were performed. A histopathological classification was structured to arrange the information on the patients and to correlate laboratory findings with clinical ones.Results: patients recruited were 154; 55 (45.5%) out of 70 patients who had a tentative diag...
