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1
tesis doctoral
Publicado 2001
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Desarrolla un nuevo modelo de computación neuronal basado en moléculas e interacciones moleculares. Es un modelo jerárquico: nivel molecular, nivel celular y nivel de organismo. El modelo se aplicó para resolver problemas de aprendizaje de máquina y tiene aplicaciones en inteligencia artificial.
2
artículo
This research sought to describe the teaching strategies used by teachers in the interaction processes of first grade students in two educational institutions in Lima. The technique used was, in the first place, observation, for which a field notebook and a checklist were used. Second, interviews were applied to teachers. Among the finds, the significance of the strategies employed, such as teamwork, dynamics of integration and assignment of roles in the modes of interaction of first grade students, was evidenced. Likewise, certain predominant attitudes were observed among some students, which evidenced the establishment of both horizontal and vertical interactions.
3
artículo
Publicado 2022
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The Soxhlet method in extracting plasticizers from PVC compounds presents various areas for improvement, such as the amount of solvent used, the time required in the process, and its costs. This study proposes replacing the Soxhlet method with the ultrasound-assisted method to reduce the time, costs, and amount of solvent used in plasticizer extraction. It also proposes using solvent recovered from previous extractions to reduce costs further. The study involved experimentation with three different grades of PVC compounds (medical, cable, and profile) to compare the recovery of plasticizers by the Soxhlet and the ultrasound-assisted methods. The plasticizers obtained were analyzed using gas chromatography, gas chromatography coupled with mass spectroscopy, and Fourier-transform infrared spectroscopy to evaluate the results of each extraction method as compared to reference co...
4
artículo
Publicado 2022
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The Soxhlet method in extracting plasticizers from PVC compounds presents various areas for improvement, such as the amount of solvent used, the time required in the process, and its costs. This study proposes replacing the Soxhlet method with the ultrasound-assisted method to reduce the time, costs, and amount of solvent used in plasticizer extraction. It also proposes using solvent recovered from previous extractions to reduce costs further. The study involved experimentation with three different grades of PVC compounds (medical, cable, and profile) to compare the recovery of plasticizers by the Soxhlet and the ultrasound-assisted methods. The plasticizers obtained were analyzed using gas chromatography, gas chromatography coupled with mass spectroscopy, and Fourier-transform infrared spectroscopy to evaluate the results of each extraction method as compared to reference co...
5
artículo
Publicado 2015
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The research involved two stages: In the first one, screening methodology was performed toevaluate the effect of the most significant factors: temperature, time and ratio raw material:solvent (MP: S) on the extraction of fructooligosaccharides (FOS) and reducing sugars (AR)from yacon flour. A factorial arrangement 2K were used; the levels for the factors were: time5-40 minutes; ratio MP: S 1:10-1:70 g / ml; temperature 30-90 ° C; responses variables wereextraction yield of FOS and AR. The results indicated that only the factor ratio MP: S hadsignificant effect on the extraction of FOS and AR (p-value <0.05). In the next stage, manylevels of ratio MP: S (1:10 to 1: 100 g / ml) were evaluated holding for time 5 minutes andtemperature at 30°C. Maximum extraction and greatest recovery of the extract was obtainedwith ratio MP:S 1:30. Finally, two kinetic models were used to describe the ...
6
artículo
The coffee industry, coffee shops and restaurants are in constant expansion and growth. Consequently, large amounts of Spent Coffee Grounds (SCG) are generated, which are solid coffee residues obtained after the ground coffee leaching process. This residue can be reused because of its compounds as phenolics. The objective of the present study was to evaluate the effect of extraction time (30-90 min) assisted by ultrasound (45kHz and 50 W), liquid-solid ratio (10-40 ml/g) and ethanol concentration (20-93.8%) in the total phenolic compounds (CFT) content expressed as mg gallic acid/g SCG dry matter. Surface response methodology (MSR) was used, as an efficient technique that minimizes the number of experiments, through the central rotational compound design (DCCR) to determine the effect of these 3 factors and to perform the optimization of the extraction process conditions of total phenoli...
7
artículo
The coffee industry, coffee shops and restaurants are in constant expansion and growth. Consequently, large amounts of Spent Coffee Grounds (SCG) are generated, which are solid coffee residues obtained after the ground coffee leaching process. This residue can be reused because of its compounds as phenolics. The objective of the present study was to evaluate the effect of extraction time (30-90 min) assisted by ultrasound (45kHz and 50 W), liquid-solid ratio (10-40 ml/g) and ethanol concentration (20-93.8%) in the total phenolic compounds (CFT) content expressed as mg gallic acid/g SCG dry matter. Surface response methodology (MSR) was used, as an efficient technique that minimizes the number of experiments, through the central rotational compound design (DCCR) to determine the effect of these 3 factors and to perform the optimization of the extraction process conditions of total phenoli...
8
artículo
The coffee industry, coffee shops and restaurants are in constant expansion and growth. Consequently, large amounts of Spent Coffee Grounds (SCG) are generated, which are solid coffee residues obtained after the ground coffee leaching process. This residue can be reused because of its compounds as phenolics. The objective of the present study was to evaluate the effect of extraction time (30-90 min) assisted by ultrasound (45kHz and 50 W), liquid-solid ratio (10-40 ml/g) and ethanol concentration (20-93.8%) in the total phenolic compounds (CFT) content expressed as mg gallic acid/g SCG dry matter. Surface response methodology (MSR) was used, as an efficient technique that minimizes the number of experiments, through the central rotational compound design (DCCR) to determine the effect of these 3 factors and to perform the optimization of the extraction process conditions of total phenoli...
9
artículo
The coffee industry, coffee shops and restaurants are in constant expansion and growth. Consequently, large amounts of Spent Coffee Grounds (SCG) are generated, which are solid coffee residues obtained after the ground coffee leaching process. This residue can be reused because of its compounds as phenolics. The objective of the present study was to evaluate the effect of extraction time (30-90 min) assisted by ultrasound (45kHz and 50 W), liquid-solid ratio (10-40 ml/g) and ethanol concentration (20-93.8%) in the total phenolic compounds (CFT) content expressed as mg gallic acid/g SCG dry matter. Surface response methodology (MSR) was used, as an efficient technique that minimizes the number of experiments, through the central rotational compound design (DCCR) to determine the effect of these 3 factors and to perform the optimization of the extraction process conditions of total phenoli...
10
artículo
Publicado 2012
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This paper presents an investigation of the extraction of essential oils by steam distillation. The process is analyzed and a model is developed for the extraction of essential oil of eucalyptus in pilot scale with a steam flow of 5.73 g / min. According to the model Dunckhorst-Houghton, which considers the effect of axial dispersion, and the use of optimization procedures to establish the model parameters, excellent agreement was obtained between the amount of oil extracted theoretical and experimental.
11
artículo
The aim of this study was to extract collagen from the waste produced in the processing of anchovies (canned and surimi). To this end, non-collagenous proteins was solubilized with a solution of 0,1N sodium hydroxide and neutralized with successive washes with water (pH close to neutral). Then, the residues were decalcified with a EDTA 0,5M solution; degreased with butanol 10% and finally the collagen protein were solubilized with acetic acid 0,5M and precipitated with sodium chloride 2,6M. Collagen precipitated was dialyzed and lyophilized. The hydroxyproline content (Hip) were quantified in waste and lyophilized collagen, getting the values of 6,5 and 52,9 mg of hydroxyproline/g sample, respectively. The solubility of lyophilized collagen decreased about 40% at a concentration of 12% NaCl. Gel electrophoresis showed a strong band of approximately 110 kDa molecular weight that correspon...
12
tesis de grado
Publicado 2014
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En los orígenes de la ciencia de la computación todo el énfasis estuvo puesto en desarrollar sistemas que automatizaran tareas que se hacían manualmente. Este era suficiente desafío. En la actualidad, se han automatizado muchas tareas y el gran desafío es cómo mejorar la capacidad de los sistemas para alcanzar nuevos requerimientos: agregar nuevas interfaces, combinar múltiples fuentes de datos en una sola, interactuar con dispositivos móviles y reemplazar viejas aplicaciones con nuevas. La tendencia de hoy es hacia un paradigma orientado a los procesos, donde las aplicaciones cubren la actividad global de la empresa y las herramientas son los BPMS (Business Process Management Systems o Sistemas de Gestión de Procesos de Negocio). Los modelos actuales resultan insuficientes porque son pobres en su integración y se orientan a describir datos y transacciones. El cambio de enfoqu...
13
artículo
Publicado 2020
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In order to evaluate the forms of interaction in the main Instagramers from Peru and Colombia, an exploratory analysis of their profiles was carried out on the Instagram audiovisual platform during 2019. For this reason, firstly, the Heepsy tool was used to establish the influencers with greater impact within the platform in both countries and then, through the monitoring tools Fan Page Karma and Social Blade, to determine a set of variables and parameters regarding their interaction. The results show that the audience index is higher for Instagramers from Colombia than for the ones from Peru. In addition, there is a clear trend among digital audiences to value content through likes as a sign of interaction with it, but on the other hand, there is a representative decrease in expressing their impressions with words and comments regarding what they observe; this is also established by the...
14
artículo
Publicado 2020
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In order to evaluate the forms of interaction in the main Instagramers from Peru and Colombia, an exploratory analysis of their profiles was carried out on the Instagram audiovisual platform during 2019. For this reason, firstly, the Heepsy tool was used to establish the influencers with greater impact within the platform in both countries and then, through the monitoring tools Fan Page Karma and Social Blade, to determine a set of variables and parameters regarding their interaction. The results show that the audience index is higher for Instagramers from Colombia than for the ones from Peru. In addition, there is a clear trend among digital audiences to value content through likes as a sign of interaction with it, but on the other hand, there is a representative decrease in expressing their impressions with words and comments regarding what they observe; this is also established by the...
15
artículo
Publicado 2023
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Diabetic foot ulcers are microvascular lesions considered one of the most serious complication of people with diabetes, by not having sufficient caution and care they can evolve into ulcers with difficult and slow healing, coupled with all existing pharmacological treatments, people of indigenous communities complement the treatments by using Traditional Medicine (TM) with adjuvant treatments based on plant extracts that help the wound healing process. The objective was to know the use of Aloe vera, honney, Calotropis procera, Caléndula officinalis, Plectranthus amboinicus y Centella asiática, Jatropha multífida, Phellodendri, Annona muricata L, however, most localized clinical studies are performed in rodents and in-vitro. This is due to the methodologies established to determine the safety and efficacy of use in humans and in this way, through the multidisciplinary health team, coll...
16
artículo
Publicado 2010
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In this paper we have studied the effect of the moisture from the eucalyptus leaf and the time of extraction on the yield of essential oil and the production cost. We took into account parameters such as steam temperature, pressure extraction, porous bed, steam flow and temperature of condensation. A Central Composite Rotational Design was used to evaluate optimum extraction areas and the cost that would follow, searching always to increase yields and reduce costs. According to this design, the extraction with the lowest production costs (0.57 Nuevos Soles by mL of essential oil) is reached when the leaves have moisture between 25 and 30% and are extracted with times between 98 and 126 min.
17
artículo
Publicado 2010
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In this paper we have studied the effect of the moisture from the eucalyptus leaf and the time of extraction on the yield of essential oil and the production cost. We took into account parameters such as steam temperature, pressure extraction, porous bed, steam flow and temperature of condensation. A Central Composite Rotational Design was used to evaluate optimum extraction areas and the cost that would follow, searching always to increase yields and reduce costs. According to this design, the extraction with the lowest production costs (0.57 Nuevos Soles by mL of essential oil) is reached when the leaves have moisture between 25 and 30% and are extracted with times between 98 and 126 min.
18
artículo
Publicado 2020
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Fructooligosaccharides (FOS) are fructose polymers, linked by β-glucosidic bonds (2-1), considered low caloric food sweeteners with prebiotic function and can be obtained from sucrose by biosynthesis. The fruits of the carob tree (Prosopis pallida) contain mainly carbohydrates where sucrose stands out. For this reason, the production of FOS from carob extract was optimized using a pectinase from A. aculeatus. The response surface methodology using was applied to optimize the parameters that affected production: time, temperature and carob extract; then they were verified experimentally. The biosynthesis process of FOS was carried out with carob extract at the concentrations of 20, 35 and 50 ° Bx, Pectinase at 10, 35 and 61mg, at 45, 55 and 65 °C for 0,5, 9,5 and 18 h, with stirring at 150 rpm The analysis methods were glucose oxidase and AOAC 999.03, for glucose and FOS respectively a...
19
artículo
Publicado 2021
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Authors are very thankful to CONCYTECFONDECYT, process E041-01 (Contract number 123-2018-FONDECYT-BM-IADT/AV), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Process 305250/2019-1, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES) Finance Code 001 and Programa Nacional de Pós-Doutorado (PNPD).
20
artículo
Publicado 2002
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It is to create the Ministry of Production in an attempt to support a national plan of production, a sector to formulate policy and direct the production, processing and extractive activity. Industrialization and commercialization of aquatic and agricultural and mining metallurgical promote, coordinate and guide his development, maximizing the productivity of each of the products you need the domestic market and for export projection.