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1
artículo
Publicado 2019
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When we refer to pain, we are faced with an unpleasant sensation that causes certain reactions in the human body that prevent its production, so it is of vital importance to understand what the symptomatology of pain is, how it is produced and how it can be avoided. production, there are cases where the pain becomes pathological where found in the patient's thoughts, therefore the present work tries to demonstrate that its production can be avoided in the face of intense painful situations that occur when working in the recovery of the mobility of the patient. articulation of the knee, which by its nature is painful, added to the fear of feeling pain on the part of the patient does not help the patient's recovery, the experimentation consists of taking the pain from the approach of not thinking about it and relaxing and evaluating it by an environment of cerebral analysis through the lev...
2
artículo
Publicado 2021
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The aim of the study was to analyze the marking of the cataloged pattern of brain image to unlearn from a philosophical conceptualization. From July 2020 to June 2021 the study was carried out at the National University ¨San Luis Gonzaga¨, Ica, Peru. After giving 15 training workshops and 5 postgraduate courses for research training, four university teachers were randomly selected where two levels of intellectual function were considered (1st: memory and 2nd: learning), but only the intellectual function of learning through five practical criteria of conceptual evaluation (conceptual framework of apprehension, conceptual operationalization, recognition of conceptual image, conceptual application and conceptual imprecision). Through an example that consisted of the quantitative technique of measurement by psycho-labor test of pencil and paper, the evaluation of the level of intellectual...
3
objeto de conferencia
In the present project it is focused on patients Amotrophy Lateral Sclerosis (ALS), so these patients do not have control of their motor functions therefore are unable to move on their own, requiring third party assistance to move with his wheelchair. Patients of Amyotrophic Lateral Sclerosis do not lose their cognitive ability, which is why you can use it to control his wheelchair as part of a computer chandler system using Cyton board of open BCI brain signals is extracted and with the help of deep learning classification of signals, so the patient can move their own means be held. In this project it was possible to perform communication computer brain, in addition to the proper functioning of the system, in addition it was possible to implement a security system that protects the patient against accidents, so the patient is safer to move; whole system gives the patient, partial indepe...
4
artículo
Publicado 2020
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Objective: To describe the treatment of acute ischemic strokes with intravenous rtPA and determine the factors associated with the functional outcomes of patients treated with thrombolysis in a Peruvian hospital. Material and Methods: A prospective, longitudinal cohort study of patients with ischemic stroke who received rtPA over a period of 3 years was performed. The association of demographic and clinical data with functional status was assessed 3 months after the intervention. Simple and multivariate Poisson regression models were performed to evaluate associations with functional prognosis, and Relative Risk (RR) with a 95% confidence interval (CI) was used as a measure of association. Results: During the study period, 74 patients (1.19% of the total) received IV thrombolysis, and 68.18% of them achieved functional independence (mRS 0-2) at 90 days. We found a mortality of 6%, an int...
5
artículo
Publicado 2025
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Background: Disorders of gut–brain interaction (DGBI) are multifactorial. Early-life events are proposed as factors involved in their etiopathogenesis. The relationship between mode of delivery, prematurity, and DGBI development remains unclear. This study examines whether cesarean delivery and prematurity contribute to early childhood DGBI. Methods: Caregivers of children aged 1 month to 4 years from four Colombian cities participated in a cross-sectional study. Pediatricians completed the Spanish-validated Questionnaire of Pediatric Gastrointestinal Symptoms Rome IV (QPGS-IV). Data of children born by cesarean delivery and prematurity were compared with controls. Categorical data were analyzed using Fisher’s exact test, and odds ratios (ORs) with 95% confidence intervals (CIs). Results: DGBIs were identified in 26.6% of children, with functional constipation (FC) being the most pre...
6
artículo
Introduction: Computed tomography (CT) is the primary diagnostic tool used in evaluating acute Trauma Brain Injury (TBI). Single-photon Emission Computerized Tomography (SPECT) is been used in TBI, with better results in brain functional evaluation than CT or MRI. Relationship between CT and SPECT after TBI was studied, but neurocognitive status is not included. Patients may have neurocognitive impairment with none or few abnormalities in structural images from CT. Material and Methods: Twenty patients between 16 and 60 years old with mild or moderate trauma brain injury were studied. CT scan, brain SPECT and neuropsychological evaluation were made at admission. Obtained data was matched. Results: CT scan and SPECT were abnormal in 16 and 19 patients. CT scan showed 15 brain lesions and SPECT 29 brain lesions. All patients with neurocognitive impairment had an abnormal SPECT. Discussion:...
7
artículo
Publicado 2016
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The following essay introduces a number of researches, reflections, and quotes extremely relevant onareas such as neuroscience, pedagogy and psychology. Each area specializes in certain subjects but,in some moment, they meet and share common ground, nourish each other and help us understandmore and more the complex world of knowledge, the functioning of the brain and the human behavior.Our concern today is the decline of the word, reading and its possibilities, as well as the increase ofmedia interests such as the television that has deeply depreciated in the last three decades. We believethat certain trendy practices today have not contributed to improve our production and intellectuality;instead, said practices have led to an alarming mental impoverishment easy to observe in teenagers(even undergraduate students) and children.We will start recalling some general discoveries in the fiel...
8
artículo
Publicado 2016
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The following essay introduces a number of researches, reflections, and quotes extremely relevant onareas such as neuroscience, pedagogy and psychology. Each area specializes in certain subjects but,in some moment, they meet and share common ground, nourish each other and help us understandmore and more the complex world of knowledge, the functioning of the brain and the human behavior.Our concern today is the decline of the word, reading and its possibilities, as well as the increase ofmedia interests such as the television that has deeply depreciated in the last three decades. We believethat certain trendy practices today have not contributed to improve our production and intellectuality;instead, said practices have led to an alarming mental impoverishment easy to observe in teenagers(even undergraduate students) and children.We will start recalling some general discoveries in the fiel...
9
artículo
Publicado 2018
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The neuroscientist advances and developments help us to comprehend the brain function and how can we take advantage of these advances for the benefit of a specific area. Learning and language has a physiological and cognitive explanation. Both explanations are considered for the neuroscience andthe neuropedagogical. How, when and why do we learn are questions that have a response in the light of the neuroscience. The acquisition of language is done in a natural manner without forgetting the brain complex process. The acquisition of a second language benefits to the brain and provides it with new neural nets.
10
artículo
Publicado 2018
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The neuroscientist advances and developments help us to comprehend the brain function and how can we take advantage of these advances for the benefit of a specific area. Learning and language has a physiological and cognitive explanation. Both explanations are considered for the neuroscience andthe neuropedagogical. How, when and why do we learn are questions that have a response in the light of the neuroscience. The acquisition of language is done in a natural manner without forgetting the brain complex process. The acquisition of a second language benefits to the brain and provides it with new neural nets.
11
artículo
Publicado 2022
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Ischemic brain injury represents a major cause of death worldwide with limited treatment options with a narrow therapeutic window. Accordingly, novel treatments that extend the treatment from the early neuroprotective stage to the late regenerative phase may accommodate a much larger number of stroke patients. To this end, stem cell-based regenerative therapies may address this unmet clinical need. Several stem cell therapies have been tested as potentially exhibiting the capacity to regenerate the stroke brain. Based on the long track record and safety profile of transplantable stem cells for hematologic diseases, bone marrow-derived mesenchymal stromal cells or mesenchymal stromal cells have been widely tested in stroke animal models and have reached clinical trials. However, despite the translational promise of MSCs, probing cell function remains to be fully elucidated. Recognizing th...
12
artículo
Publicado 2016
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This paper intends to approach to the notion of ‘brain death’ as a paradigm used to determine ‘clinical death’, not as the death of the brain and the survival of the body, but rather as the cessation of all vital functions, i.e. death per se. This notion of ‘brain death’ will be analyzed based on what neurosciences can contribute today regarding the nature and complexity of the brain, and simultaneously, breaking new grounds when attempting to give an answer to this matter.
13
artículo
Publicado 2016
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This paper intends to approach to the notion of ‘brain death’ as a paradigm used to determine ‘clinical death’, not as the death of the brain and the survival of the body, but rather as the cessation of all vital functions, i.e. death per se. This notion of ‘brain death’ will be analyzed based on what neurosciences can contribute today regarding the nature and complexity of the brain, and simultaneously, breaking new grounds when attempting to give an answer to this matter.
14
artículo
Publicado 2021
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Background: Heterotopic ossification (OH) is a complication described in patients with neurological damage. Case report: Patient who suffered a multiple trauma and traumatic brain injury (TBI), with fractures and neurological deficit secondary to TBI, who presented several heterotopic ossifications (OH) during his evolution that compromised the achievement of functional objectives. The main manifestation was swelling and limitation of the articular range (RA) for the extension of the left hip and knee, which kept the lower left limb (MI) flexed, preventing standing and walking. He was diagnosed as osteoma secondary to neurological trauma and received structured medical management, which included surgical intervention: “resection of the osteoma and tenotomy in hamstrings”, obtaining improvement of the joint range, chieving standing and walking with biomechanical support. Discussion: T...
15
artículo
The need to develop a BCI brain- computer interface system for the control of a robotic arm in Peru arises from the possibility of interconnecting the human nervous system with a robotic or mechatronic system, and using this concept to recover some motor function. Brain Computer Interface (BCI) is a communication system based on the recording of brain signals (EEG). The electroencephalogram is the basis and support of the BCI technology. It is a novel technology that allows human-machine interaction in a virtual or physical environment, through a communication channel between the central nervous system and a robotic device. In recent years, the aforementioned systems have caused the interest of important research centers worldwide.
16
artículo
Publicado 2011
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Background: Maca, Lepidium meyenii walp, is a plant that grows in Peruvian Andes’ highlands. It is used as food because of its nutritional value and its ethnical and medical properties related to fertility and vitality. Currently public interest has increased on food and dietetic supplements that contain active principles like polyphenol compounds with inhibitory effect on acetylcholinesterase and butyrylcholinesterase activities, thus improving cognitive functions through mechanisms yet unknown; for this reason maca has been proposed as an adaptogen that increases energy and resistance and diminishes stress. Objectives: To determine the energetic effect of yellow maca on memory and learning by biochemical tests, in an animal model of weaning rats. Design: Experimental study. Setting: Biochemistry and Nutrition Research Center, Faculty of Medicine, Universidad Nacional Mayor de San Mar...
17
artículo
Publicado 2024
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Exposure to high-altitude hypobaric hypoxia provides a useful pathophysiological model for studying the brain's response to reduced oxygen availability. In this study, gene expression was analyzed in different brain regions (hypothalamus, striatum, hippocampus, and cerebral cortex) of rats exposed to 3153 m a.s.l., focusing on markers of inflammation and cellular adaptation: NLRP3, IL-1β, and HIF-1α. For the samples obtained from each brain region, three consecutive procedures were performed following the manufacturer's instructions: total RNA extraction, reverse transcription to complementary DNA (cDNA), and quantification by real-time PCR (qPCR). Findings showed limited induction of NLRP3, whereas IL-1β and HIF-1α were markedly overexpressed. These results suggest that cerebral hypoxia triggers a sustained inflammatory response during the 28-day exposure period, accompanied by HI...
18
artículo
Publicado 2019
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Intelligence is a construct of notable impact in our sociocultural context, related to a wide range of conceptual and operational definitions which originate positions that highlights cognitive and abstract elements and emotional and social skills, as well was perspectives that are focused on processes underlying the intelligent performance, such as in the case of executive functions (EFs), which are configured as cognitive processes that make it possible the self-regulation (Miyake & Friedman, 2012). Similarly, there are approaches that give intelligence a relevant and predictive role of school performance, an aspect strengthened by the psychometric perspective, where the concept of intelligence has been closely linked to learning. In this line, we also find the classical perspective of crystallized Intelligence of Cattell (1943), which refers to the knowledge acquired through educa...
19
artículo
Publicado 2022
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Introducción: La enfermedad oncológica cerebral de tipo estesioneuroblastoma es un tumor poco frecuente, pero con extensiones que pueden llegar hasta la base del cráneo y, en ocasiones, puede presentar metástasis a grandes distancias que comúnmente llegan hasta los pulmones. Esta investigación tuvo como propósito, identificar y analizar los cambios neuropsicológicos antes y después de la intervención quirúrgica. Método: Se consideró apenas un participante para este estudio de caso, un hombre con 53 años que residía en la ciudad de Lisboa. Se aplicó un screening constituido por diversas subpruebas de la WISC y la figura compleja de Rey, además se evaluó la regulación emocional a partir de la prueba EADS. Resultados: En la evaluación preoperatoria se verificaron alteraciones significativas para la atención, memoria, funciones ejecutivas y todos...
20
artículo
Publicado 2025
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The relationship between executive functions (EF), creative personality, and academic performance in Argentine university students was examined. A total of 248 students (M = 22.97 years, SD = 4.43) from various Argentine provinces participated. The Adult Executive Functioning Inventory (ADEXI), the Cognitive Flexibility Scale, the Creative Behavior Scale (ECC), and the Creative Personality Scale (EPC) were used, along with academic performance data and sociodemographic information. Data were collected online through Google Forms and analyzed using Spearman correlations and mediation analysis with robust Maximum Likelihood estimator and Bootstrap. Cognitive flexibility exhibited the most robust correlation with grade point average (r = .281, p < .001), followed by working memory difficulties (r = -.234, p < .001). Creative personality correlated positively with grade point average (...
