Tuberculosis: Searching for mycobacterium antigens inglomerull

• Autores: Maita, Rosa, Seminario, Violeta, Jara, Delia, Sánchez, Luis, Palomino, Felio, Torres, Ebert, Meléndez, Rosa, Victorio, John, Escalante, Isabel
• Formato: artículo
• Fecha de Publicación: 1996
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revistas - Universidad Nacional Mayor de San Marcos
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/4743
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/anales/article/view/4743
• Nivel de acceso: acceso abierto
• Materia: Tuberculosis; bacillus Calmette Guerin; membranoproliferative glomerulonephritis; streptavidivin method; Bacillus Calmette Guerin; Glomerulonefritis Membranoproliferativa; Método Streptavidin

The aim of this work done at the Instituto de Patologia de la Facultad de Medicina-UNMSM was to know the frequency of secondary tuberculous glomerulonephritis, through a retrospective study of 42 autopsies and 3 post mortem biopsies in 45 tuberculous patients with glomerulonephritis. Mycobacterium antigens in renal glomeruli were identified by immunomicroscopy. The glomerular lesion was classified with the 1988 WHO classification of renal diseases. Clinical pathological correlation was done. We concluded : a) 37,78% of the cases in this study had Mycobacterium antigens positive in the glomeruli; b) In all the positive cases the glomerular lesion was classified as membranoproliferative or mesangiocapillary glomerulonephritis; c) Most of the patients with secondary mesangiocapillary glomerulonephritis had chronic pulmonary tuberculosis.