El estudio titulado GESTIÓN DEL DESARROLLO EN LA COMUNIDAD NATIVA ALTO CUBANTIA, PANGOA PROVINCIA SATIPO PROGRAMA NACIONAL PAIS 2021, tiene por fin: Determinar la influencia de la gestión del Programa Nacional País en el desarrollo de la comunidad nativa Alta Cubantia, San Martin de Pangoa Provincia de Satipo – 2021. Metodología: de método científico, de enfoque cuantitativo, de nivel básico, de diseño no experimental, descriptivo, correlacional. El estudio se llevó a cabo en la comunidad nativa Alta Cubantia, perteneciente al centro poblado Cubantia, San Martin de Pangoa, de la Provincia de Satipo. La muestra la constituyeron 67 pobladores de la comunidad a quienes se les aplico un cuestionario estructurado. Los resultados demuestran la gestión del Programa Nacional País influye de acuerdo a la percepción de la población, en un nivel medio (61.2%), en un nivel alto (32.8%...

OBJECTIVES: To determine the presence of p53 mutations among patients with colorectal carcinoma and their relationship with the tumoral size and with Dukes’ stage classification. MATERIALS AND METHODS: Anatomopathological specimens of 40 cases of colorectal carcinoma from the Hospital Central FAP, taken between 1987 and 1996, were re-examined. For detecting p53 protein mutations, the streptavidin-biotin immunoperoxidase immunohistochemical assay with do-7 antibody was used, pre-processing the samples with microwaves. RESULTS: All cases were adenocarcinomas, mostly moderately differentiated; 18 were in Dukes B, 16 Dukes in C, 4 in Dukes A and 2 in Dukes D stage. Tumoral size was directly related with Dukes’ stage, having a mean size of 5,5 cm3 for Dukes A, and 50,12 cm3 for Dukes D. There was a presence of p53 mutation in 55% of cases; the higher p53 expression, both the higher Dukesâ...

The aim of this work done at the Instituto de Patologia de la Facultad de Medicina-UNMSM was to know the frequency of secondary tuberculous glomerulonephritis, through a retrospective study of 42 autopsies and 3 post mortem biopsies in 45 tuberculous patients with glomerulonephritis. Mycobacterium antigens in renal glomeruli were identified by immunomicroscopy. The glomerular lesion was classified with the 1988 WHO classification of renal diseases. Clinical pathological correlation was done. We concluded : a) 37,78% of the cases in this study had Mycobacterium antigens positive in the glomeruli; b) In all the positive cases the glomerular lesion was classified as membranoproliferative or mesangiocapillary glomerulonephritis; c) Most of the patients with secondary mesangiocapillary glomerulonephritis had chronic pulmonary tuberculosis.

We studied 51 patient from Lima and other peruvian districts with vitiligo, acquired idiopatic illness, that is due to gradual melanocyte destruction and immunological disturbances. The purposes were the early diagnosis of other associated autoimmune diseases and to do a clinic pathological correlation including family data. We studied circulating autoantibodies and skin biopsis in immunomicroscopy. Generalized vulgaris vitiligo was the most frequent type of vitiligo. The 33.3% of all the cases had other associated autoimmune disease and 37.2% hypersensitivity I disease. The 19.6% has family members with vitiligo and 31.2% with other autoimmune diseases.