The effect of adding oregano (Origanum vulgare) essential oil and dry ginger (Zingiber officinale) in the diet on body weight gain, feed intake and feed conversion rate was evaluated in 624 male Cobb 500 broiler chicks randomly assigned into four treatments with four replicates of 39 chicks each. Intestine and liver samples from four broilers per treatment were collected at day 14 and two at day 42 after treatment to determine possible histological toxic alterations and to determine the intestinal histomorphometry of jejunum. The treatments were: APC, Bacitracin methylene disalicylate (1 kg/MT of feed) and colistine sulfate 8% (0.25 kg/MT); SPC, without growth promoter; AEO, oregano essential oil (1 kg /MT); and JD, dryy ginger (10 kg/MT). There was no statistical difference between groups in body weight gain, feed intake and feed conversion rate. Group AEO showed slightly larger villi b...

The effect of adding oregano (Origanum vulgare) essential oil and dry ginger (Zingiber officinale) in the diet on body weight gain, feed intake and feed conversion rate was evaluated in 624 male Cobb 500 broiler chicks randomly assigned into four treatments with four replicates of 39 chicks each. Intestine and liver samples from four broilers per treatment were collected at day 14 and two at day 42 after treatment to determine possible histological toxic alterations and to determine the intestinal histomorphometry of jejunum. The treatments were: APC, Bacitracin methylene disalicylate (1 kg/MT of feed) and colistine sulfate 8% (0.25 kg/MT); SPC, without growth promoter; AEO, oregano essential oil (1 kg /MT); and JD, dryy ginger (10 kg/MT). There was no statistical difference between groups in body weight gain, feed intake and feed conversion rate. Group AEO showed slightly larger villi b...

We explored the concentration patterns of the bioactive metabolite plumericin produced by Himatanthus tarapotensis (Apocynaceae) under different edaphic conditions and variations in rainfall intensity, as well as its potential role in the chemical defense against insect herbivores. Values of plumericin concentration from leaves were obtained by High-Performance Liquid Chromatography, and evaluated as a function of differences in soil types, variation of precipitation, and variation of the abundance of insect herbivores, using first a Repeated Measures Correlation (rmcorr) and then a Generalized Linear Mixed Model (GLMM) analysis. Plumericin concentration is highly variable among plants, but with a significantly higher concentration in plants growing on clay soil compared to that of the white-sand soil habitat (p < 0.001). Plumericin concentration is not affected by precipitation. The cat...

Se evaluaron in vitro extractos de siete plantas medicinales utilizadas específicamente contra la leishmaniasis cutánea en la región de Madre de Dios, en el Perú, contra las formas de promastigotes y amastigotes axénicos de la Leishmania amazonensis. Una de ellas mostró interesantes actividades leishmanicidas (IC50 = 5g/ml en amastigotes). El aislamiento bioguiado del extracto eólico de la corteza del tallo de Himatanthus sucuuba (Spruce ex Mull. Arg.) Woodson (Apocynaceae) proporcionó los iridoides espirolactona isoplumericina y plumericina. Esta última mostró una reducción de la infección de los macrófagos similar a la del medicamento de referencia Amphotericin B (IC50 = 0,9 y 1M, respectivamente). Estos hallazgos validan el uso tradicional de Himatanthus sucuuba en el tratamiento de la leishmaniasis cutánea (Uta) en el Perú