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1

artículo

Exportation of MDR TB to europe from setting with actively transmitted persistent strains in peru

Publicado por
Acosta F., Agapito J., Cabibbe A.M., Cáceres T., Sola C., Pérez-Lago L., Abascal E., Herranz M., Meza E., Klotoe B., Muñoz P., Rossolini G.M., Bartoloni A., Tortoli E., Cirillo D.M., Gotuzzo E., García De Viedma D.

Publicado 2019

Enlace

We performed a cross-border molecular epidemiology analysis of multidrug-resistant tuberculosis in Peru, Spain, and Italy. This analysis revealed frequent transmission in Peru and exportation of a strain that recreated similar levels of transmission in Europe during 2007-2017. Transnational efforts are needed to control transmission of multidrug- resistant tuberculosis globally. © 2019, Centers for Disease Control and Prevention (CDC). All rights reserved.

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artículo

Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections

Publicado por
Abascal E., Herranz M., Acosta F., Agapito J., Cabibbe A.M., Monteserin J., Ruiz Serrano M.J., Gijón P., Fernández-González F., Lozano N., Chiner-Oms Á., Cáceres T., Pintado P.G., Acín E., Valencia E., Muñoz P., Comas I., Cirillo D.M., Ritacco V., Gotuzzo E., García de Viedma D.

Publicado 2020

Enlace

It is relevant to evaluate MDR-tuberculosis in prisons and its impact on the global epidemiology of this disease. However, systematic molecular epidemiology programs in prisons are lacking. A health-screening program performed on arrival for inmates transferred from Peruvian prisons to Spain led to the diagnosis of five MDR-TB cases from one of the biggest prisons in Latin America. They grouped into two MIRU-VNTR–clusters (Callao-1 and Callao-2), suggesting a reservoir of two prevalent MDR strains. A high-rate of overexposure was deduced because one of the five cases was coinfected by a pansusceptible strain. Callao-1 strain was also identified in 2018 in a community case in Spain who had been in the same Peruvian prison in 2002–5. A strain-specific-PCR tailored from WGS data was implemented in Peru, allowing the confirmation that these strains were currently responsible for the majo...

3

artículo

Building a network for multicenter, prospective research of central nervous system infections in South America: process and lessons learned.

Publicado por
Delgado, A., Nelson, Christina, Mori, Nicanor, Thanh Ton, Zunt, Joseph, Kochel, T., Romero, A., Gadea, N., Tilley, D., Ticona, E., Soria, J., Celis, V., Huanca, D., Rivas, M., Stiglich, M., Sihuincha, M., Donayre, G., Celis, J., Romero, R., Tam, N., Tipismana, M., Espinoza, I., Rozas, M., Peralta, A., Sanchez, E., Vasquez, L., Muñoz, P., Ramirez, G., Reyes, I.

Publicado 2018

Enlace

Las redes de colaboración de multicentros son esenciales para el avance de la investigación y mejorando la atención clínica de variedad de condiciones. La redes de investigación son particularmente importantes para las infecciones del sistema nervioso central, las cuales son difíciles de estudiar. Se revisa nuestra experiencia de desarrollo de redes de investigación en encefalitis en doce hospitales de cinco ciudades peruanas desde el año 2009, y se presentan sugerencias prácticas para ayudar a otros grupos de investigación en áreas de recursos limitados.