1
tesis de maestría
Publicado 2023
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Este informe de consultoría ofrece un análisis exhaustivo y recomendaciones estratégicas para shoes.pe, un mercado en línea emergente para productores locales de calzado en El Porvenir, Trujillo, Perú. En primer lugar, se presenta la organización y su contexto operativo, allanando el camino para profundizar posteriormente en el problema clave. Identificando de este modo el reto principal que consiste en convencer a los productores locales de calzado para que vendan en línea a través de shoes.pe. A continuación, se lleva a cabo una revisión exhaustiva de la bibliografía, que incluye siete áreas temáticas diferentes relacionadas con la investigación establecida y las perspectivas de la industria para proporcionar una base sólida para la siguiente exploración. Seguidamente, se emplean metodologías cualitativas y cuantitativas para realizar un análisis en profundidad del pr...
2
tesis de maestría
Publicado 2023
Enlace
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Este informe de consultoría ofrece un análisis exhaustivo y recomendaciones estratégicas para shoes.pe, un mercado en línea emergente para productores locales de calzado en El Porvenir, Trujillo, Perú. En primer lugar, se presenta la organización y su contexto operativo, allanando el camino para profundizar posteriormente en el problema clave. Identificando de este modo el reto principal que consiste en convencer a los productores locales de calzado para que vendan en línea a través de shoes.pe. A continuación, se lleva a cabo una revisión exhaustiva de la bibliografía, que incluye siete áreas temáticas diferentes relacionadas con la investigación establecida y las perspectivas de la industria para proporcionar una base sólida para la siguiente exploración. Seguidamente, se emplean metodologías cualitativas y cuantitativas para realizar un análisis en profundidad del pr...
3
artículo
Publicado 2020
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Objective: To search for all the information and available evidence on infection with SARS-CoV-2, a virus that appeared during the first 4 months of 2020, and pregnancy. Methods: Systematic review in PubMed and Google Scholar databases until April 25, 2020. We searched for published articles related to pregnant women infected with SARS-CoV-2. There was no language restriction. The search was extended to the references of the articles found. Results: In pregnant women with COVID-19, more than 90% of patients evolve mildly, 2% require intensive care. One maternal death has been reported. Prematurity occurs in approximately 25% of the cases, with predominance of late preterm infants; premature rupture of membranes presents in about 9%. Perinatal mortality is lower or similar to that of the general population, and vertical transmission has not been shown. Conclusions: Obstetrician-...
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5
revisión
Publicado 2018
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HRvD and SS were funded by the Wellcome Trust of Great Britain ( 089276/Z/09/Z and 106680/Z/14/Z ) and a Li Ka Shing Foundation–University of Oxford Global Health Program strategic award ( LG17 ). JCBA has been awarded a doctoral scholarship by CIENCIACTIVA, an initiative of the Peruvian National Council of Science, Technology and Technological Innovation (CONCYTEC); grant contract number 231-2015-FONDECYT. HY was supported by the National Science Fund for Distinguished Young Scholars ( No.81525023 ), the National Natural Science Foundation of China ( No. 81473031 ), the Li Ka Shing Oxford Global Health Programme ( No.B9RST00-B900.57 ).
6
artículo
Publicado 2023
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Background: PD-1 inhibitors combined with chemotherapy have shown efficacy in gastric or gastro-esophageal junction cancer. We compared the efficacy and safety of pembrolizumab plus chemotherapy with placebo plus chemotherapy in participants with locally advanced or metastatic HER2-negative gastric or gastro-esophageal junction adenocarcinoma. Methods: KEYNOTE-859 is a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial, done at 207 medical centres across 33 countries. Eligible participants were aged 18 years and older with previously untreated histologically or cytologically confirmed locally advanced or metastatic HER2-negative gastric or gastro-esophageal junction adenocarcinoma and an Eastern Cooperative Oncology Group performance status of 0 or 1. Patients were randomly assigned (1:1) to receive pembrolizumab or placebo 200 mg, administered intravenously every 3...
7
artículo
Publicado 2017
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Purpose To describe benefits and toxicities of adjuvant endocrine therapies in women younger than 35 years with breast cancer (n = 582) enrolled in the Suppression of Ovarian Function Trial (SOFT) and Tamoxifen and Exemestane Trial (TEXT). Methods In SOFT, women still premenopausal after surgery with or without chemotherapy were randomly assigned to tamoxifen alone, tamoxifen plus ovarian function suppression (OFS), or exemestane plus OFS. In TEXT, all received OFS with or without concomitant chemotherapy and were randomly assigned to exemestane plus OFS or tamoxifen plus OFS. We summarize treatment efficacy, quality of life, and adherence of the cohort of women younger than 35 years in SOFT and TEXT, alongside data from the cohort of older premenopausal women. Results For 240 human epidermal growth factor receptor 2-negative patients younger than 35 years enrolled in SOFT after receivin...
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artículo
The recognition of space weather hazards is increasingly growing, highlighting the importance of monitoring and forecasting it. High precision satellite positioning techniques have become essential in various areas of social and economic infrastructure. However, it is well-known that Global Navigation Satellite Systems (GNSS) can be affected by space weather-induced ionospheric variations. This poses a challenge as it can impact the reliability and accuracy of GNSS-based systems. Space weather phenomena can also have significant effects on aviation systems and electric power grids. Given that many of these phenomena occur on a global scale, it is crucial to have a comprehensive monitoring and observation network. Currently, numerous ground-based observations are managed by local government or academic bodies. In contrast, space-based observations are typically operated by space agencies,...
