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artículo
Publicado 2020
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Tsunamis are rare events compared with the other natural disasters, but once it happens, it can be extremely devastating to the coastal communities. Extensive inland penetration of tsunamis may cause the difficulties of understanding its impact in the aftermath of its generation. Therefore the social needs to technologies of detecting the wide impact of great tsunamis have been increased. Recent advances of remote sensing and technologies of image analysis meet the above needs and lead to more rapid and efficient understanding of tsunami affected areas. This paper provides a review of how remote sensing methods have developed to contribute to post-tsunami disaster response. The evaluations in the performances of the remote sensing methods are discussed according to the needs of tsunami disaster response with future perspective. ©2020 by the authors. Licensee MDPI, Basel, Switzerland.
2
artículo
Publicado 2023
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Background: PD-1 inhibitors combined with chemotherapy have shown efficacy in gastric or gastro-esophageal junction cancer. We compared the efficacy and safety of pembrolizumab plus chemotherapy with placebo plus chemotherapy in participants with locally advanced or metastatic HER2-negative gastric or gastro-esophageal junction adenocarcinoma. Methods: KEYNOTE-859 is a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial, done at 207 medical centres across 33 countries. Eligible participants were aged 18 years and older with previously untreated histologically or cytologically confirmed locally advanced or metastatic HER2-negative gastric or gastro-esophageal junction adenocarcinoma and an Eastern Cooperative Oncology Group performance status of 0 or 1. Patients were randomly assigned (1:1) to receive pembrolizumab or placebo 200 mg, administered intravenously every 3...
