Introduction: In our context, there are no studies which had evaluated the markers of bone turnover in postmenopausal women with osteoporosis, considering the high rate of morbidity and mortality associated with fragility fractures. Objective: To know the biochemical features of bone metabolism in women with postmenopausal osteoporosis. Methods: A cross-sectional study. 49 women with postmenopausal osteoporosis were included. Bone mineral density in spine, hip and forearm was measured by dual x-ray absorptiometry. Calcium, phosphorus, osteocalcin, alkaline phosphatase, vitamin D and paratohormone were measured in blood. N-telopeptide of collagen type I, calcium and phosphorus were measured in urine by conventional methods. Results: The average age of the participants was 59,1± 7,5 years. The average time since menopause was 12,0 ± 7,9 years. All ...

COVID-19's lethality as well as its rapid spread are responsible for the current world crisis; therefore, from the beginning, drugs with antiviral action against this agent were sought. It is impossible, for now, to know which person in a mild state will develop a high viral load or have a predisposition to develop an extreme response from the immune system, but early treatment in mild cases would not only guarantee greater efficacy, but would avoid severe cases. Currently, there are no double blind, randomized clinical trials or meta-analyzes available to make safe decisions; meanwhile, the pandemic is advancing in our country, generating pain and death. In this context, in Peru, scientific societies have expressed the need for the use of antiviral drugs, even with little evidence, based on the probability of success prior to treatment, for their in vi...

Objectives. To determine and correlate the bone mineral density (BMD) and the biochemical markers of bone metabolism in adults 30 to 40 years old from Lima, Perú, in year 2018. Methods. A total of 84 women and 53 men, 30 to 40 years old from Lima, Perú, were submmited to a descriptive, transversal study. They did not have symptoms nor treatment for bone metabolic diseases. Information about their present health state, personal and familiar physiological and pathological history and physical examinatión were registered. BMD was measured by dual energy-X-ray absorptiometry in spine, hip and forearm. Parathormone, osteocalcine, 25-hidroxi-vitamine-D, luteinizing hormone, estradiol in women, testosterone in men, calcium, phosphorus, alkaline fosfatase, total and fractionated proteins, creatinine were measured in blood; in urine N-telopéptide, calcium and pho...