1
artículo
Publicado 2020
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A 27-year-old Peruvian woman living with human immunodeficiency virus (HIV) in clinical stage B3 and not on antiretroviral therapy presented with a ten-day history of fever, chills, night sweats and a two-day history of skin lesions. On physical examination, several erythematous-purplish lesions were found on the face and legs. Meningococcal infection was suspected and ceftriaxone was started. Blood culture grew nontyphoidal Salmonella enterica. A biopsy of the skin lesions showed leukocytoclastic vasculitis (LCV); therefore, corticosteroids were added. After two weeks of antibiotic and corticosteroid treatment, the lesions had resolved, but they recurred two days after treatment with prednisone was stopped. Corticosteroids and combination antiretroviral therapy were started simultaneously and the lesions resolved without recurrence. HIV infection has been associated with higher rates of...
2
artículo
Publicado 2024
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Objective: This scoping review aimed to describe studies that evaluate the management of cryptococcal meningitis (CM) using cerebrospinal fluid (CSF) shunts, types of shunts used, and clinically relevant patient outcomes. Methods: We searched in the following databases: PubMed, Web of Science/Core collection, Embase, the Cochrane Library, and clinicaltrials.gov on 1 April 2022. We included two-arm and one-arm cohort studies that evaluated clinically relevant patient outcomes. Case reports were used to describe the type of CSF shunts used and the rationale behind its selection. The selection and extraction processes were independently performed by two authors. Results: This study included 20 cohort studies and 26 case reports. Only seven cohort studies compared two groups. Ventriculoperitoneal shunt was the most commonly used type of shunt (82.1%). The main indications for placing a shunt...
3
tesis de grado
Publicado 2021
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Introducción: la población LGBTI busca atención médica con menor frecuencia y en etapas de enfermedad más avanzadas que la población general. Objetivos: identificar los factores asociados a la falta de búsqueda de atención médica en la población LGBTI en Perú en 2017. Metodología: se realizó un estudio observacional transversal analítico de fuente secundaria usando los datos de la Primera Encuesta Virtual para Personas LGBTI, 2017 en Perú. Se elaboró un modelo de regresión de Poisson con varianza robusta para estimar las razones de prevalencias cruda y ajustada. Resultados: se incluyeron 5 646 participantes en el estudio. El 15.85% no buscó atención médica. El 74.04% vivía en Lima y Callao. El 29.84% no contaba con seguro de salud, mientras que el 46.42% refirió problemas de salud mental. Se encontró que la falta de búsqueda de atención médica fue más frecuente...
4
tesis de grado
Publicado 2020
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Objetivo: Determinar la asociación entre los factores sociodemográficos y reproductivos, y la fecundidad adicional no deseada (FAND) en el Perú según la Encuesta Demográfica y de Salud Familiar (ENDES) del 2018. Materiales y métodos: Se realizó un estudio observacional, analítico transversal, a partir de la ENDES del Perú del año 2018. La FAND es una variable que se creó a partir de la diferencia numérica entre la fecundidad obtenida y la fecundidad deseada. Se categorizó la variable FAND en dos categorías: la diferencia numérica positiva correspondió a presencia de FAND; y la diferencia numérica negativa o nula correspondió a ausencia de FAND. Se realizó una regresión de Poisson, tanto cruda como ajustada. Resultados: Se analizaron los datos de 6944 mujeres entre 40 y 49 años, con una edad promedio de 44,3. Se halló una prevalencia de FAND de 72,5% (IC95%: 70,4%-74...
5
artículo
Publicado 2022
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Background: the neurosurgical burden of disease is high worldwide. Information regarding this in Peru is limited. We aim to describe epidemiological characteristics and temporal distribution of the neurosurgical burden of disease in a high complexity center in Peru. Material and Methods: we carried a cross-sectional analytical study using the surgery registry from the neurosurgical department of Hospital Nacional María Auxiliadora in Lima-Peru, which contains registers from 2008 to 2020. Diagnoses were classified into main diagnosis, a variable with 10 levels, each a broad category; and specific diagnosis, defining the etiology. Absolute and relative frequencies were described on a diagnosis basis. Temporal distribution was described using a heatmap. Chi-squared test was used to evaluate association between variables and sex. Results: there were 2948 surgeries in the studied period. The...
6
artículo
We have read with interest the short communication published by Segovia-Juarez et al., 2020 in Respiratory Physiology & Neurobiology establishing that high altitude reduces the infection rate of COVID-19 but not the case fatality rate in the Peruvian setting. We support this hypothesis, however there could be an important number of under registered deaths on account of a low rate of diagnostic tests performed per inhabitant and mostly in symptomatic patients (Pasquariello and Stranges, 2020).
7
artículo
Publicado 2023
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Marijuana is the most widely used illicit drug in the world, especially among young people. This study is relevant to policy makers because it expands the knowledge regarding drug use in vulnerable youth, al-lowing health authorities to reduce marijuana consumption via educa-tional, family, and governmental strategies and policies. The objective of this study was to determine the prevalence of frequent marijuana consumption and its associated factors in young people before admission to juvenile detention centers in Peru. The data was taken from the 2016 National Population Census of the Youth Diagnostic and Rehabilitation Centers in Peru. The final sample was made up of 1,848 people with ages between 14 and 22 years old, with a median age of 17 (95.6% males). The variable frequent marijuana consumption was de-fined as the use of marijuana at least once a week, prior to entering the cente...
8
artículo
Publicado 2023
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Background: Actinomycosis is an unusual chronic bacterial infection, even rarer in people living with HIV. It is not considered an AIDS-defining disease. However, the role in co-presentation or overlap with other opportunistic conditions of advanced HIV is unknown. Case presentation: A 49-year-old Peruvian male presented with a 4-month history of dysphagia, odynophagia, hyporexia and wasting. He underwent an upper digestive endoscopy, in which ulcers with a necrotic center were observed, therefore, the initial diagnostic assumption was esophageal cancer. Subsequent pathology report excluded neoplasms and confirmed the diagnosis of actinomycosis. Serology for human immunodeficiency virus was requested, yielding a positive result. Antimicrobial treatment with amoxicillin and antiretroviral therapy were indicated, with slow clinical improvement. After 4 months, epigastric discomfort present...
9
artículo
Publicado 2020
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Leprosy (Hansen’s disease) is a chronic granulomatous condition caused by Mycobacterium leprae, a microorganism that affects the skin and Schwann’s cells. Making a diagnosis of this condition is difficult in non-endemic areas because of low clinical suspicion. During the 2012-2019 time period, three cases of Hansen’s disease were diagnosed and treated in the ID service of Dos de Mayo Hospital. The average time history of the disease was 4 years. Patients started their condition with the appearance of pruriginous papular lesions affecting specific body regions, progressing to generalized nodular lesions. Paresthesia and tactile, thermal, pain, and vibratory hypoesthesia were found. These manifestations later progressed to anesthesia. Diagnosis was made through bacilloscopy in lymphatic fluid and skin node biopsy. Clinical features for each patient are also described. We emphasize th...
10
artículo
Publicado 2020
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Leprosy (Hansen’s disease) is a chronic granulomatous condition caused by Mycobacterium leprae, a microorganism that affects the skin and Schwann’s cells. Making a diagnosis of this condition is difficult in non-endemic areas because of low clinical suspicion. During the 2012-2019 time period, three cases of Hansen’s disease were diagnosed and treated in the ID service of Dos de Mayo Hospital. The average time history of the disease was 4 years. Patients started their condition with the appearance of pruriginous papular lesions affecting specific body regions, progressing to generalized nodular lesions. Paresthesia and tactile, thermal, pain, and vibratory hypoesthesia were found. These manifestations later progressed to anesthesia. Diagnosis was made through bacilloscopy in lymphatic fluid and skin node biopsy. Clinical features for each patient are also described. We emphasize th...
11
informe técnico
Publicado 2023
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El curso de Internado en Medicina es un curso de especialidad en la carrera de medicina de carácter práctico dirigido a los estudiantes del 13 ciclo, que busca desarrollar competencias específicas de práctica clínica (diagnóstico, promoción, prevención y tratamiento) y de profesionalismo (sentido ético, legal y responsabilidad profesional) a través de la rotación en las áreas de Medicina. El internado constituye la parte final de la carrera en la cual el estudiante aplica las competencias que ha desarrollado a lo largo de su formación. Es una etapa de preparación pre profesional.
12
informe técnico
Publicado 2023
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El curso Integración Clínico-Patológica 3 es un curso de especialidad de la carrera de medicina, de carácter teórico, que se dicta a los estudiantes del 8vo ciclo de la carrera de medicina y que contribuye con el desarrollo de la competencia general Uso de la Información para el Pensamiento Crítico (nivel 3) y la competencia específica Práctica clínica (nivel 2). A través del curso los estudiantes integran los mecanismos fisiopatológicos con la patogénesis y manifestaciones clínicas de los problemas de salud que se abordan en relación al sistema vascular y corazón, enfermedades inflamatorias, enfermedades infecciosas, entre otras. La comprensión de esta integración permite a los estudiantes establecer las bases del diagnóstico clínico y las pautas del manejo de los problemas de salud abordados. 1
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informe técnico
Publicado 2023
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El curso de Internado en Ginecología y Obstetricia es un curso de especialidad en la carrera de medicina de carácter práctico dirigido a los estudiantes del ciclo 14, que busca desarrollar las competencias generales Ciudadanía, COmunicación oral y escrita, Uso de la información para el pensamiento crítico y las competencias específicas de Profesionalismo y Práctica Clínica a través de la rotación en las áreas de Ginecología y Obstetricia. El internado constituye la parte final de la carrera en la cual el estudiante aplica las competencias que ha desarrollado a lo largo de su formación. Es una etapa de preparación pre profesional.
