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artículo
“Objective To assess the association between inadequate prenatal care (IPNC) and Low birth weight (LBW) in newborns of singleton gestation mothers in Peru. Methods We performed a secondary analysis of data from the 2019 Demographic and Health Survey. We included a total of 10,186 women of reproductive age (15 – 49 years) who had given birth to a singleton child in the last 5 years. The dependent variable was LBW (< 2500 g). The independent variables were IPNC (inadequate: when at least one of the IPNC components was absent [number of PNC visits ≥ 6, first PNC visit during the first trimester, compliance with PNC visit contents, and PNC visits provided by trained health personnel]) and each of its components. We evaluated the association using logistic regression models to estimate crude odds ratios and adjusted odds ratios (aOR) and their respective 95% confidence intervals (95% CI...
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“Objective To assess the association between inadequate prenatal care (IPNC) and Low birth weight (LBW) in newborns of singleton gestation mothers in Peru. Methods We performed a secondary analysis of data from the 2019 Demographic and Health Survey. We included a total of 10,186 women of reproductive age (15 – 49 years) who had given birth to a singleton child in the last 5 years. The dependent variable was LBW (< 2500 g). The independent variables were IPNC (inadequate: when at least one of the IPNC components was absent [number of PNC visits ≥ 6, first PNC visit during the first trimester, compliance with PNC visit contents, and PNC visits provided by trained health personnel]) and each of its components. We evaluated the association using logistic regression models to estimate crude odds ratios and adjusted odds ratios (aOR) and their respective 95% confidence intervals (95% CI...
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Objective: To assess the association between inadequate prenatal care (IPNC) and Low birth weight (LBW) in newborns of singleton gestation mothers in Peru. Methods: We performed a secondary analysis of data from the 2019 Demographic and Health Survey. We included a total of 10,186 women of reproductive age (15–49 years) who had given birth to a singleton child in the last 5 years. The dependent variable was LBW (<2500 g). The independent variables were IPNC (inadequate: when at least one of the IPNC components was absent [number of PNC visits≥6, first PNC visit during the first trimester, compliance with PNC visit contents, and PNC visits provided by trained health personnel]) and each of its components. We evaluated the association using logistic regression models to estimate crude odds ratios and adjusted odds ratios (aOR) and their respective 95% confidence intervals (95%CI). Re...
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tesis de grado
Objetivo: Explorar la asociación entre el uso de medicamentos prehospitalarios y el desarrollo de desenlaces fatales en pacientes que requirieron hospitalización por enfermedad por coronavirus-2019 (COVID-19). Métodos: Este estudio de cohorte retrospectivo incluyó a pacientes adultos que fueron hospitalizados debido a COVID-19. Los datos demográficos, clínicos y de laboratorio, el historial de medicación prehospitalaria y la evolución de los desenlaces fatales (uso de oxigenoterapia de alto flujo, ingreso a la unidad de cuidados intensivos [UCI] o mortalidad) se extrajeron de los registros médicos de los pacientes que ingresaron debido a COVID-19 al Hospital Nacional Carlos Seguín Escobedo de Arequipa, Perú; durante julio a septiembre de 2021, período posterior a la segunda ola de casos de COVID-19 en el Perú. La supervivencia se analizó mediante el modelo de riesgos propor...
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Introduction: Variegate porphyria (VP) is a rare disease, resulting from mutation of the protoporphyrinogen oxidase (PPOX) enzyme gene, and it is characterized by cutaneous manifestations and acute neuro-visceral symptoms. Case report: We describe the case of a 21-year-old woman from Peruvian highlands. The patient came to the emergency department for abdominal pain, quadriparesis and reddish urine. The patient also presented the syndrome of inappropriate secretion of antidiuretic hormone (SIADH), motor neuropathy and respiratory failure. These clinical features were diagnosed as consequence of a porphyria crisis. The specific diagnosis was made with an elevated urinary porphobilinogen level (185.7 mg/24hours) and genetic analysis, which showed a rare pathogenic variant of the PPOX gene (nucleotide change: c.78C>A and protein change: p.Cys26*). The patient required intensive care unti...
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Introduction: Hypercalcemia secondary to vitamin D intoxication is a rare condition resulting from inadequate prescription. It is characterized by nonspecific symptomatology and can produce severe neurological, muscular, gastrointestinal, renal, and cardiovascular manifestations. Clinical case: We describe the case of an 86-year-old woman with a history of vitamin D supplementation for three months after hip arthroplasty. The initial presentation was gastrointestinal symptoms and sensorimotor disturbance. Hypercalcemia was found upon evaluation. After ruling out the main organic causes, vitamin D intoxication was suspected, which was confirmed after testing for 25-hydroxyvitamin D levels. Correction of hypercalcemia was performed, and the patient had a favorable clinical evolution.  Conclusion: It is important to consider vitamin D intoxication as a differential diagnosis of hyperca...
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Coronavirus disease 2019 has put the world in a health emergency. Searching for information on the Internet largely reflects people's interest in this pandemic. Objective: Conduct an exploratory analysis of Internet search trends during the 2019 coronavirus disease outbreak. Methods: Google Trends was used to provide data on the relative volume of Google searches for terms related to 2019 coronavirus disease. The evaluation period was from January 01 to May 17, 2020. Results: The search term used to know this pandemic was “coronavirus”, the most searched symptom was “fever”, followed by “sore throat” and “cough”, in addition, the interest of users to know the transmission routes of the acute respiratory syndrome coronavirus 2. As for preventive measures, the most searched term was “stay home”, followed by “facial masks”, “social distancing” and “washing hand...
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La enfermedad COVID-19 ha puesto en emergencia sanitaria al mundo. La búsqueda de información a través de internet refleja en gran medida el interés de las personas acerca de esta pandemia. El presente estudio tuvo como objetivo determinar la asociación entre el volumen relativo de búsqueda del término combinado [coronavirus + covid-19 + "nuevo coronavirus" + covid + SARS-CoV-2] y el número de casos confirmados y de muertes diarias por la COVID-19. Se utilizó Google TrendsTM para proporcionar datos sobre el volumen relativo de búsqueda en Google de los términos seleccionados y compararlos con el número de casos confirmados y de muertes diarias por la COVID-19 en los 10 países más afectados de Latinoamérica, reportados por el panel de control de la Organización Mundial de la Salud. El período de evaluación fue del 01 de enero al 14 de junio del año 2020. Para obtener la...
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“Background: Booster doses have been described as effective in reducing hospitalizations and deaths from the new variants. However, its coverage is heterogeneous in Latin America and the Caribbean (LAC), one of the regions most affected by the pandemic. We aimed to assess the factors associated with not receiving a coronavirus disease 2019 (COVID-19) vaccine booster dose in adults from LAC. Methods: We analyzed a secondary database compiled by the University of Maryland and Facebook assessing the global impact of COVID-19. We included Facebook users over 18 years of age who resided in LAC and responded to the survey between February 13, 2022, and March 14, 2022. We evaluated sociodemographic characteristics, comorbidities, food, and economic insecurity, mental health, and vaccination-related practices. We calculated crude (cPR) and adjusted (aPR) prevalence ratios with their respective...
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“Background: Booster doses have been described as effective in reducing hospitalizations and deaths from the new variants. However, its coverage is heterogeneous in Latin America and the Caribbean (LAC), one of the regions most affected by the pandemic. We aimed to assess the factors associated with not receiving a coronavirus disease 2019 (COVID-19) vaccine booster dose in adults from LAC. Methods: We analyzed a secondary database compiled by the University of Maryland and Facebook assessing the global impact of COVID-19. We included Facebook users over 18 years of age who resided in LAC and responded to the survey between February 13, 2022, and March 14, 2022. We evaluated sociodemographic characteristics, comorbidities, food, and economic insecurity, mental health, and vaccination-related practices. We calculated crude (cPR) and adjusted (aPR) prevalence ratios with their respective...
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We aimed to conduct a scoping review to assess the profile of retracted health sciences articles authored by individuals affiliated with academic institutions in Latin America and the Caribbean (LAC). We systematically searched seven databases (PubMed, Scopus, Web of Science, Embase, Medline/Ovid, Scielo, and LILACS). We included articles published in peer-reviewed journals between 2003 and 2022 that had at least one author with an institutional affiliation in LAC. Data were collected on the year of publication, study design, authors' countries of origin, number of authors, subject matter of the manuscript, scientific journals of publication, retraction characteristics, and reasons for retraction. We included 147 articles, the majority being observational studies (41.5%). The LAC countries with the highest number of retractions were Brazil (n = 69), Colombia (n = 16), and Mexico (n = 15)...
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“Objetivo: Evaluar los factores asociados a la lactancia materna adecuada (LMA) entre las madres peruanas durante el 2019. Materiales y métodos: Realizamos un análisis secundario de la base de datos de la Encuesta Demográfica y de Salud Familiar (ENDES) 2019 de Perú. La LMA se definió con base en las recomendaciones de la Organización Mundial de la Salud, que la definió como iniciar la lactancia materna dentro de la primera hora de vida y continuar con lactancia materna exclusiva hasta los 6 meses. Para determinar los factores asociados con ABF, se utilizó un modelo lineal generalizado de Poisson con función log-link. Se calcularon razones de prevalencia ajustadas (RPa) con sus respectivos intervalos de confianza al 95% (IC 95%). Resultados: Se identificó una prevalencia de LBA de 48,1% entre 11.157 mujeres que relataron al menos un hijo en los últimos cinco años. La mayor...
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“Objetivo: Evaluar los factores asociados a la lactancia materna adecuada (LMA) entre las madres peruanas durante el 2019. Materiales y métodos: Realizamos un análisis secundario de la base de datos de la Encuesta Demográfica y de Salud Familiar (ENDES) 2019 de Perú. La LMA se definió con base en las recomendaciones de la Organización Mundial de la Salud, que la definió como iniciar la lactancia materna dentro de la primera hora de vida y continuar con lactancia materna exclusiva hasta los 6 meses. Para determinar los factores asociados con ABF, se utilizó un modelo lineal generalizado de Poisson con función log-link. Se calcularon razones de prevalencia ajustadas (RPa) con sus respectivos intervalos de confianza al 95% (IC 95%). Resultados: Se identificó una prevalencia de LBA de 48,1% entre 11.157 mujeres que relataron al menos un hijo en los últimos cinco años. La mayor...
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Existe una imperiosa necesidad de evaluar los instrumentos de procrastinación actuales, con especial atención a la Escala de Procrastinación Académica (EPA), ampliamente utilizada en Latinoamérica, cuya dimensionalidad ha experimentado variaciones constantes en la literatura. Para ello se aplicó la EPA a 1308 estudiantes universitarios siguiendo un muestreo no probabilístico. Inicialmente, se observó que el ítem 4 reflejaba una actividad cotidiana más que comportamientos directos de procrastinación. Posteriormente, se exploraron diversas variaciones de la EPA, conforme a la literatura y las propuestas del presente estudio. El modelo de dos factores, excluyendo el ítem 4 y con correlación de errores entre los ítems 6 y 7, demostró ser adecuado en términos de ajuste, logrando la invarianza entre los participantes de ambos sexos. El estudio concluye que se debe emplear la EP...
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Objetivo: Evaluar la producción científica de los institutos de salud de Perú en Scopus, 2010-2022. Métodos: Estudio bibliométrico realizado en Scopus durante septiembre del 2022, en 14 institutos de salud especializados públicos de Perú. Incluimos estudios originales que tuvieran al menos un autor de alguno de los institutos. Resultados: Los institutos incluidos publicaron entre 0 y 347 artículos originales (H-index entre 0 y 51). Los institutos de la ciudad de Lima fueron los que tuvieron mayor producción. En los siete institutos con mayor producción, el porcentaje de artículos con autor corresponsal del instituto evaluado varió entre 22.3% y 36.7%, y el porcentaje de estudios que declararon ser financiados por el instituto varió entre 0% y 11.6%. Conclusión: La producción científica de los institutos evaluados fue heterogénea, a predominio de aquellos ubicados en Lima...
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Objective: To evaluate the scientific production of Peruvian health institutes in Scopus, 2010-2022. Methods: We conducted a Bibliometric study in Scopus during September 2022, in 14 public specialized health institutes of Peru. We included original studies with at least one author from one of the institutes. Results: The institutes included published between 0 and 347 original articles (H-index between 0 and 51). The institutes in the city of Lima were the ones with the highest production. In the seven institutes with the highest production, the percentage of articles with a corresponding author from the institute evaluated ranged from 22.3% to 36.7%, and the percentage of studies that reported being financed by the institute ranged from 0% to 11.6%. Conclusion: The scientific production of the evaluated institutes was heterogeneous, with a predominance of those located in Lima. The ins...
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Introduction: Due to the high incidence of mpox in Peru and the poor knowledge about this disease among healthcare workers in non-endemic countries, it is crucial to determine the knowledge status of Peruvian physicians. Methodology: We conducted an analytical cross-sectional study based on an online survey from August to September 2022. Physicians who had a medical license and lived and practiced medicine in Peru were included. To evaluate the factors associated with a higher level of knowledge, we used crude (cPR) and adjusted (aPR) prevalence ratios with 95% confidence intervals (95% CI) using Poisson regression. Results: We included 463 physicians. The mean age was 36.6 (SD: 10.3) years, and most were male (58.1%). Regarding knowledge, the median knowledge score was 14 [IQR: 13 to 15] out of 17 points. In terms of knowledge gaps, only 60.7% of the participants knew that there was an ...