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acid based » acid base (Expander búsqueda), acido base (Expander búsqueda), ai based (Expander búsqueda)
1
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
2
artículo
Publicado 2011
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The current understanding of acid-base physiology states that all changes in the blood, pH, as well as variations in a healthy state and during disease occur through changes in 3 variables: (a) Carbon dioxide (CO2), (b) electrolyte relative concentration, and (c) weak acid concentration. Internal milieu and acid-base disturbances generate alterations inthree areas: a) direct damage in multiple organs and systems, (b) a compensatory response to the disturbance, which may be suitable or incomplete, and (c) functional alterations in immune cells. The classically used Henderson-Hasselbalch equation for the classification of acid-base disorders in respiratory (abnormal CO2) and metabolic (abnormalbicarbonate) and for the “anion gap” calculation, but this equilibrium equation assumes that albumin and phosphate concentrations are very close to normal, a condition that is not necessari...
3
artículo
Publicado 2021
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This research focused on the synthesis of a functional alginate-based material via chemical modification processes with two steps: oxidation and reductive amination. In previous alginate functionalization with a target molecule such as cysteine, the starting material was purified and characterized by UV-Vis,1 H-NMR and HSQC. Additionally, the application of FT-IR techniques during each step of alginate functionalization was very useful, since new bands and spiked signals around the pyranose ring (1200–1000 cm−1) and anomeric region (1000–750 cm−1) region were identified by a second derivative. Additionally, the presence of C1-H1 of β-D-mannuronic acid residue as well as C1-H1 of α-L-guluronic acid residue was observed in the FT-IR spectra, including a band at 858 cm−1 with characteristics of the N-H moiety from cysteine. The possibility of attaching cysteine molecules to an a...
4
artículo
Publicado 2015
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Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been observed both within and among individuals, but the genetic factors responsible for this variation are largely unknown. The goals of this research, therefore, were to assemble, characterize, and annotate the fruit transcriptome of M. dubia in order to reconstruct metabolic pathways and determine if multiple pathways contribute to AsA biosynthesis.RESULTS: In total 24,551,882 high-quality sequence reads were de novo assembled into 70,048 unigenes (mean length = 1150 bp, N50 = 1775 bp). Assembled sequences were annotated using BLASTX against public databases such as TAIR, GR-protein, FB, MGI, RGD, ZFIN, SGN, WB, TIGR_CMR, and JCVI-CMR with 75.2 % of unigenes having annotations. Of the...
5
artículo
Publicado 2025
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Purple corn (Zea mays L.) is a superfood native to Peru, highly regarded for its functional properties and commonly used in the preparation of traditional beverages and desserts, such as chicha morada and mazamorra morada. Following processing, the corn cobs remaining as a byproduct retain significant amounts of bioactive compounds with potential for utilization. This study proposes their use as a primary component in the production of teas. To ensure product safety, the moisture content, total ash, and counts of enterobacteria and aflatoxins in the raw materials were first evaluated. Fourteen formulations were developed, varying in the proportions of corn cobs, quince, stevia, cinnamon, and cloves, as well as extraction times (5 and 10 minutes at 100 °C) with hot water. Two rapid sensory evaluation methods using consumer panels were applied sequentially: Flash Profile (FP) and Check-...
6
artículo
Publicado 2020
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The study of the complex ultracellular processes of nucleic acids is a subject debated as a scientific argument in favor of Intelligent Design (ID). The objective of this work was to analyze some molecular processes of the nucleic acids that suggest the confirmation of the ID theory, through the technique of documentary content analysis. First, the chemical structure of DNA and the combination of nitrogenous bases reflects that the genetic information of each created being is an original mixture of nitrogenous bases that makes each individual unique in the history of the world. Secondly, by studying the processes of DNA replication and repair, it is observed that each enzyme fulfills its function in a coordinated and organized manner avoiding the occurrence of errors and, should this occur, the cell has had very fine repair mechanisms. that correct these alterations in the best possible ...
7
artículo
Publicado 2020
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The study of the complex ultracellular processes of nucleic acids is a subject debated as a scientific argument in favor of Intelligent Design (ID). The objective of this work was to analyze some molecular processes of the nucleic acids that suggest the confirmation of the ID theory, through the technique of documentary content analysis. First, the chemical structure of DNA and the combination of nitrogenous bases reflects that the genetic information of each created being is an original mixture of nitrogenous bases that makes each individual unique in the history of the world. Secondly, by studying the processes of DNA replication and repair, it is observed that each enzyme fulfills its function in a coordinated and organized manner avoiding the occurrence of errors and, should this occur, the cell has had very fine repair mechanisms. that correct these alterations in the best possible ...
8
artículo
Publicado 2017
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The alterations of the lipid metabolism and the uncertainty at the moment of selecting beneficial foods to the human body lead to the investigation of omega fatty acids. The study is based on the evaluation of the effect of three preparation methods of chía seed, before getting the oil through two extraction methods and the characterization of the lipid fraction of chia seed (Salvia hispánica L.) from Colta-Ecuador. The oil yield of the conditioned seeds showed statistical differences. Regarding the extraction method, the differences were highly significant, the use of ether in the Soxhlet equipment showed the superiority in the oil performance in a relation of approximately 2:1 versus immersion in hexane. The presence and the content of fatty acids was determined by the use of a gas chromatograph with FiD detector Agilent Technologies 5975C brand, fatty acids were separated with a cap...
9
artículo
Publicado 2016
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In this work, it has been studied the influence of oxygenated functional groups on adsorption property of an activated carbon (CA), which was prepared from aguaje seeds (Mauritia flexuosa L. F.) by a chemical activation with phosphoric acid. Later the activated carbon was oxidized with nitric acid. The adsorptive capacity of phenolic compounds such as phenol, 4-chlorophenol and 4-nitrophenol were compared using both of the adsorbents, the activated carbon (CA) and the oxidized activated carbon (ACA). The characterizations of both activated carbons were analyzed by nitrogen adsorption measurements, Boehm titration, scanning electron microscopy (SEM) and FTIR spectroscopy. The oxidized sample (ACA) showed an increase in the microporous area from 756 m2/g to 1272 m2/g, likewise ACA presented an increase in the concentration of oxygenated functional groups from 4,22 mmolH+.g-1 to 4,82 mmolH+...
10
artículo
Publicado 2020
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Our efforts are oriented to assess bovine Y-chromosome gene expression patterns. One set of genes that are of interest are the so-called X-degenerate Y-chromosome genes that are located in the male-specific region of the Y-chromosome (MSY). This region contains 95% of the DNA of the Y chromosome. These genes are single copy and have an X-chromosome homolog. Both, the Y-encoded and X-encoded homologs have ubiquitous expression profiles. However, some genes, like SRY that regulates male sex determination, have functions that are more specific. Identifying DNA sequence differences between these homologs will allow evaluation of their spatial and temporal expression patterns. Identification of the Y-encoded mRNAs and their isoforms will allow our understanding of tissue specific expression of isoforms in male tissues. The latter will facilitate our evaluation of gene function in male sex dif...
11
artículo
Publicado 2020
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Our efforts are oriented to assess bovine Y-chromosome gene expression patterns. One set of genes that are of interest are the so-called X-degenerate Y-chromosome genes that are located in the male-specific region of the Y-chromosome (MSY). This region contains 95% of the DNA of the Y chromosome. These genes are single copy and have an X-chromosome homolog. Both, the Y-encoded and X-encoded homologs have ubiquitous expression profiles. However, some genes, like SRY that regulates male sex determination, have functions that are more specific. Identifying DNA sequence differences between these homologs will allow evaluation of their spatial and temporal expression patterns. Identification of the Y-encoded mRNAs and their isoforms will allow our understanding of tissue specific expression of isoforms in male tissues. The latter will facilitate our evaluation of gene function in male sex dif...
12
tesis de grado
Publicado 2025
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Polyethylene terephthalate (PET) is a widely used material in container manufacturing, particularly in bottle production. It is characterized by its low cost and widespread availability. However, its improper disposal has significantly exacerbated global plastic pollution. For instance, less than 50% of plastic bottles are recycled. Moreover, studies indicate that this issue has led to a significant accumulation of plastic waste in the oceans, which continues to grow annually and could be considered floating islands of debris. This study proposes replacing PET with polylactic acid (PLA), a biodegradable and biocompatible polymer with suitable properties for bottle production. PLA also has a shorter decomposition time compared to PET, contributing to the reduction of carbon footprint and greenhouse gas emissions. The research methodology included a diagnostic phase to define objectives, i...
13
artículo
Publicado 2019
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The species belonging to the genus Bothrops are very important in the field of research for possessing proteolytic enzymes, which has as main characteristics to have a varied biological action and contribute to disorders in coagulation, necrosis and hemorrhage formation therefore a modern platform is needed in the study of these enzymes to be able to suggest an updated methodological model in the study of all the proteins expressed by a biological system that allows us to know the current status of the species, as well as to use this information in the biotechnological construction of information with possible future therapeutic purposes. The first objective is to purify and characterize one of the proteolytic enzymes present in the venom, such as metalloprotease, for which we initially worked with Hydrophobic Interaction chromatography with columns from the HITrap system, which resulted...
14
artículo
Publicado 2018
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Camu camu is a typical Amazon native fruit shrub that possesses a diploid genome, moderate genetic diversity, and population structure. The fruits accumulate several essential nutrients and synthesize L-ascorbic acid (vitamin C) in great quantities and an array of diverse secondary metabolites with corroborated in vitro and in vivo health-promoting activities. These beneficial effects include antioxidative and antiinflammatory activities, antiobesity, hypolipidemic, antihypertensive and antidiabetic effects, DNA damage and cancer protection effects, and other bioactivities. Many health-promoting phytochemicals are biosynthesized in several metabolic pathways of camu camu. Their reconstruction from the fruit transcriptome database was accomplished by our research group. These include basic metabolic pathways such as glycolysis and pentose phosphate pathway, vitamin C biosynthesis pathways...
15
tesis doctoral
Publicado 2020
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Descargue el texto completo en el repositorio institucional de la Universidade Estadual de Campinas: https://hdl.handle.net/20.500.12733/1641647
16
artículo
Publicado 2020
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Two commercial varieties of Peruvian Pouteria lucuma fruits namely “Seda” and “Beltrán” were characterized in terms of their physicochemical properties as well as their primary and secondary metabolites content and profile. Free sugars, dietary fiber, and starch comprise the main components in both varieties. Phenolic compounds derived from flavanoids (flavan-3-ols), gallic acid, and their derivatives were identified. Xanthophylls were tentatively identified based on their UV-vis spectra and enclosed the majority of the carotenoids found in lucuma. Additionally, both varieties showed to be sources of lipophilic compounds such as tocopherols (?, ?, and ?) and triterpenoids. The triterpenoid ?-amyrin was identified in a Pouteria fruit for the first time. The in vitro antioxidant capacity (AoxC) of the lipophilic fraction represented approximately 30% of the total AoxC. These resul...
17
artículo
Publicado 2024
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Peruvian fava beans (PFB) are used in traditional cuisine as a nutrient-rich, flavorful, and textural ingredient; however, little is known about their industrial properties. This study evaluated the physicochemical, nutritional, and techno-functional characteristics of PFB varieties: Verde, Quelcao, and Peruanita. PFB exhibited distinct physical characteristics, quality parameters, and morphology. The color patterns of the seed coat and the hardness were the main parameters for distinguishing them. Nutritionally, all three samples exhibited high protein (23.88–24.88 g/100 g), with high proportion of essential amino acids, high dietary fiber (21.74–25.28 g/ 100 g), and mineral content. They also contain polyphenols (0.79–1.25 mg GAE/g) and flavonoids (0.91–1.06 mg CE/g) with antioxidant potential (16.60–21.01 and 4.68–5.17 µmol TE/g for ABTS and DPPH assays, respectively). Th...
18
artículo
Publicado 2024
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The germination of quinua improves the content of polyphenols, flavonoids, amino acids, dietary fiber, vitamin E, antioxidants and other bioactive compounds, making this pseudocereal a nutritious and healthy source for the preparation of functional foods. The aim of this work was to assess the effect of the germination of quinua on the nutritional, biological and functional properties, in turn to be able to analyze the potential that this golden grain has in the food industry. For the systematic review, the databases (Scopus, Scielo and Science Direct) were used, following the PRISMA guideline and the PIO strategy (Population, Intervention, Outputs), which helped to formulate the search equations and to identify the most relevant articles of the last 5 years. The results of the bibliometric analysis showed that the germination of quinua improves the nutritional properties and the content...
19
artículo
Publicado 2024
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The germination of quinua improves the content of polyphenols, flavonoids, amino acids, dietary fiber, vitamin E, antioxidants and other bioactive compounds, making this pseudocereal a nutritious and healthy source for the preparation of functional foods. The aim of this work was to assess the effect of the germination of quinua on the nutritional, biological and functional properties, in turn to be able to analyze the potential that this golden grain has in the food industry. For the systematic review, the databases (Scopus, Scielo and Science Direct) were used, following the PRISMA guideline and the PIO strategy (Population, Intervention, Outputs), which helped to formulate the search equations and to identify the most relevant articles of the last 5 years. The results of the bibliometric analysis showed that the germination of quinua improves the nutritional properties and the content...
20
tesis de grado
Publicado 2025
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This research work focuses on the development of a plant-based mayonnaise (PBM) using Sacha Inchi seeds (Plukenetia huayllabambana) and chia seed mucilage (Salvia hispanica L.), in response to the growing demand for healthier alternatives to traditional mayonnaise. The research question posed is how the incorporation of chia mucilage can replace egg yolk in the formulation of mayonnaise while maintaining similar sensory and nutritional characteristics. The main objective of the study was to evaluate different formulations of PBM, varying the content of chia mucilage (between 1% and 3%) and the water content (43% to 45%), as well as other ingredients such as salt, oil, pepper, and lemon juice. The aim was to determine the emulsion stability, omega-3 content, rheological properties, and physicochemical characteristics of the formulations. The results showed that the formulation with 3% chi...