This investigation included 65 samples unfolded into 15 students of 20 to 26 years old, selected from Faculty Of Odontology, appcv-ently healthy; 50 patiens infected whith VIH/AIDS; 10 ofthemfrom Al to A3, 17 from Bl to B3, and 23 from el toC3 (CDC clasisification systen 1993). Thrombospondine dosage (TSP1) in plasm 0.25 to 4ug/ml. And in saliva, 4to 5 ug/ml from the control group. Thrombospondine (TSP1) in saliva ofVIH/AIDS patiens, 10 to 35 ug/ml; spit PH 6,50 to 6,70 in the control grou; in the smple ofVIH/AIDS patint ph 6.8to 7.0. The candidiasis evolves progressively prevailing the pseudo membranous type. The saliva flow and the periodontal process (gingivitis). As a constant, the caries process emigration deteriorate$ progressively, as a consequence fa the immune response deerease, aggravating the clinic bolser (buccal pathology). Evultion period of opportunistic infections, is dir...

Righty nine samples were analyzed. As control group 25 students aged 20 to 25 years old from the School of Dentistry were selected. We olso studied 44 patients with HIV-AIDS and tuberculosis, 24 patients only with HIV-AIDS, and 10 subjects aged ears old as control group. The average value of salivary proteasa activity in the control group was 0.067 / 18 horas , and we faund that the highest value and the lowest value were 0.084 and 0.045, respectively. In regards to servan proteasa in the 10 subjects used as control (suject.v without HIV-AIDS and tuberculosis), the highest value of proteasa activity was 0.092, the lowest value of proteasa activity was 0.067, and the avarage value of proteasa activity was 0.078118 horas of enzimic work. Tuberculosis and candidiasis evolved leafily by symbiotic way, and there displaced other opportunistic diseases (Kaposi sarcoma), and eve observed progres...

La trombospondina (TSPI) es una glicoproteína trimérica de P.M. 420 KD y 420,000-D (unidades de D-glucosa), proveniente de una familia de proteínas solubles, caracterizadas por poseer lugares de unión que son en número de cinco; estas son: a)Dominio heparin - sulfato proteoglicanos HSPCs; b)Dominio alfa V beta 3 integrin - arginina (Ar.) - glicina (Gly) - aspártico (Asp.) - alanina (Ala.) y con Ca 2+; c)Subdominio Valina (Val.) - treonina (Thr.) - cisteína (Cys.) - glicina (Gly.) - CD36 (receptor) o gp IV con su carboxil terminal; d)Collagen triple hélice unido al procolágeno de la trombospondina (TSPI), como se muestra en el siguiente esquema: ESQUEMA Nro. 1 Otra de las características de esta familia glicoprotéica, es considerada también como proteina moduladora en la regulación de la emigración y proliferación celular, manifestada durante la evolución de la angiogénes...

The present ínvestigation íncluided: 100 samples, 20 control groups (Universidad NAcional Agraria students), and 80 patients infected with HIVIA1DS; 25 with level 11, 35 with level III, and 20 patients with level /V Average proteinicfractions and salivary percentage were taken: Albumin 45.15%, SALIVARYALBUMIN 15.2%, GAMMAGLOBULIN 7-5.94% (SIGNIFICANCE LEVEL 1.00%).Problem Sample. - In the problem sample we can see a considerable alteration in the serical electropitoretics proteins. Spit: level 11, 22.12% albumin, gammaglobulin 77.64%, level III, albumin 16.35%, gammaglobulin 83.49%. IV 7.71% albumin and 92.37% gammaglobulin. There is a diferrential relationship between normal values of serical gammaglobulin and salivary ones, in HIV/AIDS ínfected patiens and there is an increase of bucal pathologies

This investigation included 65 samples unfolded into 15 students of 20 to 26 years old, selected from Faculty Of Odontology, appcv-ently healthy; 50 patiens infected whith VIH/AIDS; 10 ofthemfrom Al to A3, 17 from Bl to B3, and 23 from el toC3 (CDC clasisification systen 1993). Thrombospondine dosage (TSP1) in plasm 0.25 to 4ug/ml. And in saliva, 4to 5 ug/ml from the control group. Thrombospondine (TSP1) in saliva ofVIH/AIDS patiens, 10 to 35 ug/ml; spit PH 6,50 to 6,70 in the control grou; in the smple ofVIH/AIDS patint ph 6.8to 7.0. The candidiasis evolves progressively prevailing the pseudo membranous type. The saliva flow and the periodontal process (gingivitis). As a constant, the caries process emigration deteriorate$ progressively, as a consequence fa the immune response deerease, aggravating the clinic bolser (buccal pathology). Evultion period of opportunistic infections, is dir...

Se analizaron 89 muestras de las cuales 25 alumnos, de 20 a 25 años de la Facultad de Odontología seleccionados como grupo control. 44 pacientes con HIV/SIDA, TBC, 24 pacientes con HIVISIDA, 10 personas de 24 a 45, años de edad como grupo control. La actividad de la proteasa salival en el control, arrojó como promedio 0.067 (absorvencia), siendo la mayor lectura 0.084, la menor actividad 0.045. En cuanto a la proteasasa sérica en 10 personas (sin HIV/SIDA TBC). arrojó mayor actividad 0.092 y menor actividad 0.067 como promedio 0.078 (,abs.). La tuberculosis y la candidiasis evolucionan frondosamente en forma simbiótica, siendo desplazadas otras enfermedades oportunistas (Sarcoma de Kaposi), observándose disminución progresiva del flujo saliva como constante inhibición del proceso carioso, periodontales (simple gingivitis). En pacientes con HIV/SIDA TBC, la actividad de la prote...

La trombospondina (TSPI) es una glicoproteína trimérica de P.M. 420 KD y 420,000-D (unidades de D-glucosa), proveniente de una familia de proteínas solubles, caracterizadas por poseer lugares de unión que son en número de cinco; estas son: a)Dominio heparin - sulfato proteoglicanos HSPCs; b)Dominio alfa V beta 3 integrin - arginina (Ar.) - glicina (Gly) - aspártico (Asp.) - alanina (Ala.) y con Ca 2+; c)Subdominio Valina (Val.) - treonina (Thr.) - cisteína (Cys.) - glicina (Gly.) - CD36 (receptor) o gp IV con su carboxil terminal; d)Collagen triple hélice unido al procolágeno de la trombospondina (TSPI), como se muestra en el siguiente esquema: ESQUEMA Nro. 1 Otra de las características de esta familia glicoprotéica, es considerada también como proteina moduladora en la regulación de la emigración y proliferación celular, manifestada durante la evolución de la angiogénes...

The present ínvestigation íncluided: 100 samples, 20 control groups (Universidad NAcional Agraria students), and 80 patients infected with HIVIA1DS; 25 with level 11, 35 with level III, and 20 patients with level /V Average proteinicfractions and salivary percentage were taken: Albumin 45.15%, SALIVARYALBUMIN 15.2%, GAMMAGLOBULIN 7-5.94% (SIGNIFICANCE LEVEL 1.00%).Problem Sample. - In the problem sample we can see a considerable alteration in the serical electropitoretics proteins. Spit: level 11, 22.12% albumin, gammaglobulin 77.64%, level III, albumin 16.35%, gammaglobulin 83.49%. IV 7.71% albumin and 92.37% gammaglobulin. There is a diferrential relationship between normal values of serical gammaglobulin and salivary ones, in HIV/AIDS ínfected patiens and there is an increase of bucal pathologies

The tumor necrosis factor (TNF) is an important mediator of the inflammatory reactions; it seems to play a central roll in the pathogenesis of several chronic inflammatory diseases including the periodontitis. It has been demonstrated that different rates exist from TNF alpha in vitro and in vivo between the individuals, so it can be associated with the presence of certain genetic polymorphism. The purpose of this investigation is to study the degree of polymorphism of the gene TNF-alpha (-308G/A) in samples of adult Peruvian patients and analyze the relationship with periodontal processes. For the study 81 blood samples with anticoagulant EDTA of people between 25 and 52 years were collected (47,5 average ± 7,4). 11 of them were people who had severe periodontal processes (average 35,2 ± 2,3). There was a greater frequency of genotype GG (G alele for the gene TNF-alpha-308) of the 82,...

The XXI century characterized by technological noteworthy events in all disciplines of the human been. Concerning to the problematic health undoubtedly with the genetic code decipher (decade 50) and lastly with the sequence of the human genome (aims of the last century). This event comprise, also of medicine and on yours of oral cavity y bait of saliva county in what studies bases in results, shortly past will form the strategies of preparation in the diagnostic of treatment plan of the illness in hospitals and private practice convencionals of biologicals markers, genetics, test, genetics counsul; structure of this manner in news paradigms of future treatment for f illness of the oral cavity.

The tumor necrosis factor (TNF) is an important mediator of the inflammatory reactions; it seems to play a central roll in the pathogenesis of several chronic inflammatory diseases including the periodontitis. It has been demonstrated that different rates exist from TNF alpha in vitro and in vivo between the individuals, so it can be associated with the presence of certain genetic polymorphism. The purpose of this investigation is to study the degree of polymorphism of the gene TNF-alpha (-308G/A) in samples of adult Peruvian patients and analyze the relationship with periodontal processes. For the study 81 blood samples with anticoagulant EDTA of people between 25 and 52 years were collected (47,5 average ± 7,4). 11 of them were people who had severe periodontal processes (average 35,2 ± 2,3). There was a greater frequency of genotype GG (G alele for the gene TNF-alpha-308) of the 82,...

The XXI century characterized by technological noteworthy events in all disciplines of the human been. Concerning to the problematic health undoubtedly with the genetic code decipher (decade 50) and lastly with the sequence of the human genome (aims of the last century). This event comprise, also of medicine and on yours of oral cavity y bait of saliva county in what studies bases in results, shortly past will form the strategies of preparation in the diagnostic of treatment plan of the illness in hospitals and private practice convencionals of biologicals markers, genetics, test, genetics counsul; structure of this manner in news paradigms of future treatment for f illness of the oral cavity.