ABSTRACT The behavioral variant of frontotemporal dementia (bvFTD), characterized by early behavioral abnormalities and late memory impairment, is a neurodegenerative disorder with a detrimental impact on patients and their caregivers. bvFTD is often difficult to distinguish from other neurodegenerative diseases, such as Alzheimer's disease (AD), using brief cognitive tests. Combining brief socio-cognitive and behavioral evaluations with standard cognitive testing could better discriminate bvFTD from AD patients. We sought to evaluate the diagnostic accuracy of brief socio-cognitive tests that may differentiate bvFTD and AD patients with low educational levels. Methods: A prospective study was performed on 51 individuals over the age of 50 with low educational levels, with bvFTD or AD diagnosed using published criteria, and who were receiving neurological care at a multidisciplinary neur...

Introducción: La mayoría de los pacientes hospitalizados por COVID-19 presentan una manifestación neurológica, pero los marcadores para manifestaciones neurológicas específicas y cómo estas afectan los resultados clínicos aún no están claros. Objetivo: Describir la frecuencia de manifestaciones neurológicas en pacientes hospitalizados con COVID-19 y analizar su relación con marcadores y desenlaces clínicos relevantes. Métodos: Estudio retrospectivo incluyendo adultos hospitalizados por COVID-19 con al menos una manifestación neurológica. Cefalea, anosmia, ageusia, y polineuromiopatia se clasificaron como manifestaciones neurológicas inespecíficas, mientras que crisis epilepticas, disminución del nivel de conciencia, delirio, ataxia, movimientos anormales, y eventos cerebrovasculares como específicas. Asociaciones evaluadas: a) covariables clínicas y de laboratorio co...

Background: Most of hospitalized patients with COVID-19 have had neurological manifestations. However, biomarkers for specific neurological manifestations and how these affect clinical outcomes are still unclear. Objective: To describe the frequency of neurological manifestations in patients hospitalized with COVID-19 and analyze their relationship with biomarkers and relevant clinical outcomes. Methods: This retrospective cohort study included adult patients hospitalized due to COVID-19 with at least one neurological manifestation. Headache, anosmia, ageusia, and polyneuromyopathy were classified as nonspecific neurological manifestations, whereas epileptic seizures, decreased level of consciousness, delirium, encephalitis, abnormal movements, ataxia, and cerebrovascular events as specific. Assessed associations: a) clinical and laboratory covariates with the presentation of a specific ...