The aim of this study was to demonstrate that the use of irrigating solutions in surgical procedures does not alter both inflammation processes and tissue repair. Four (04) groups were formed containing 15 rats each. After being dosed with general anaesthesia, they underwent osteotomy in the tibia with tungsten carbide burs and irrigation for 15 seconds, using the following solutions in each group: A) 0,12 % chlorhexidine with cetylpyridinium 0,05 %, B) 0,12 % chlorhexidine with aspartame; C) hexetidine 0,1 %; D) 0,9 % sodium chloride. After 3, 7 and 15 days of surgery, the rats were sacrificed and tissue samples were removed for histopathological analysis. The results showed that groups in which chlorhexidine with cetylpyridinium, and chlorhexidine with aspartame were used, less inflammatory process were found than in groups of sodium chloride and hexetidine. On the process of tissue re...

The objective of the present study was to evaluate and compare the effect of Iidocaine and mepivacaine alone and associated with epinephrine on the cardiovascular and electrocardiographic parameters,60 healthy volunteers were assigned in 4 groups: A (2% lidocaine), B (2% lidocaine with epinephrine 1: 100,000); C (3% mepivacaine), D (mepivacaine 2% with epinephrine 1: 100,000). Therefore of assigned, it was injected ldental cartridge of correspondent anesthetic to each volunteer, using the nerve block anesthesia technique for the inferior mandibular nerve. In each patient was performed the measure of the heart rate, blood pressure and electrocardiogram. These measurements were carried out 5 minutes before and then 15 after minutes the administration of local anesthetic. The participants of the lidocaine 2% without vasoconstrictor group showed decline in the indicator heart rate (p <0.0...

Surgical antibiotic prophylaxis consists in the use of an antimicrobial drug in a preventive way, that must be active against microorganisms that in high frequency causes posterior infections of our surgical wounds and maintain effective tissue concentrations along the surgery procedure and the posterior time when appears the bacteremia. To reach a successful treatment is necessary to have the knowledge of the resident bactemial flora and the pathogenous flora that infects our surgical wounds. We must choose the correct antibiotic and use it by the correct time. Generally, that time does not exceed 24 hours and in the prophylactic schemes are used some antimicrobial drugs like beta-lactams, azalides lyncosamides and aminoglycosides, that must be selected depending of the medical condition of the patient and some topic related directly with the surgical technique employed.

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.

The aim of this study was to demonstrate that the use of irrigating solutions in surgical procedures does not alter both inflammation processes and tissue repair. Four (04) groups were formed containing 15 rats each. After being dosed with general anaesthesia, they underwent osteotomy in the tibia with tungsten carbide burs and irrigation for 15 seconds, using the following solutions in each group: A) 0,12 % chlorhexidine with cetylpyridinium 0,05 %, B) 0,12 % chlorhexidine with aspartame; C) hexetidine 0,1 %; D) 0,9 % sodium chloride. After 3, 7 and 15 days of surgery, the rats were sacrificed and tissue samples were removed for histopathological analysis. The results showed that groups in which chlorhexidine with cetylpyridinium, and chlorhexidine with aspartame were used, less inflammatory process were found than in groups of sodium chloride and hexetidine. On the process of tissue re...

The objective of the present study was to evaluate and compare the effect of Iidocaine and mepivacaine alone and associated with epinephrine on the cardiovascular and electrocardiographic parameters,60 healthy volunteers were assigned in 4 groups: A (2% lidocaine), B (2% lidocaine with epinephrine 1: 100,000); C (3% mepivacaine), D (mepivacaine 2% with epinephrine 1: 100,000). Therefore of assigned, it was injected ldental cartridge of correspondent anesthetic to each volunteer, using the nerve block anesthesia technique for the inferior mandibular nerve. In each patient was performed the measure of the heart rate, blood pressure and electrocardiogram. These measurements were carried out 5 minutes before and then 15 after minutes the administration of local anesthetic. The participants of the lidocaine 2% without vasoconstrictor group showed decline in the indicator heart rate (p <0.0...

Surgical antibiotic prophylaxis consists in the use of an antimicrobial drug in a preventive way, that must be active against microorganisms that in high frequency causes posterior infections of our surgical wounds and maintain effective tissue concentrations along the surgery procedure and the posterior time when appears the bacteremia. To reach a successful treatment is necessary to have the knowledge of the resident bactemial flora and the pathogenous flora that infects our surgical wounds. We must choose the correct antibiotic and use it by the correct time. Generally, that time does not exceed 24 hours and in the prophylactic schemes are used some antimicrobial drugs like beta-lactams, azalides lyncosamides and aminoglycosides, that must be selected depending of the medical condition of the patient and some topic related directly with the surgical technique employed.

The presence of adverse drug reactions with local anesthetics takes us to the search of effective alternatives to this drugs. 60 albino rabbits divided into 6 groups were submifted to infiltrative anesthetic technique in the maxilla with lidocaine, mepivacaine, bupivacaine, chlorpheniramine and dimenhidrinate, in front of sodium chloride 0,9%. The pain threshold belzavior was evaluated with electrical stimulation from Ruhnkorff s bobbin behind the drllg application and comparison between groups was made. The wlzite llsed drugs elevated the pain threshold, with a better response of lidocaine. Both local anesthetics and antihistamine drugs produced an effective local anesthesia, without tissue damage.

The aim of the study was to evaluate the possible modifications in the arterial pressure, corporal weigh and creatinine cleareance in urine gathered during 24 hours, in healthy young people, under therapy with two non steroidal anti inflammatory drugs (NSAID’s); one of them not selective to Ciclooxigenase (Ibuprofen) and a selective inhibitor of Ciclooxigenase - 2 (Celecoxib), during three days in standardized dose, in comparison with a control group that was administered placebo, in a double blind study. The results indicate that there are not statistically significant differences among the three groups, for the clinical and laboratory evaluated parameters (p <0,05). We conclude that a short term therapy with the used NSAID’s doesn’t produce clinical impact modifications in the arterial pressure, corporal weigh and creatinine cleareance in urine gathered during 24 hours.

Desde la aparición del hombre ha habido una sensación temida, incluso por aquellos más "valientes": la odontalgia o dolor dental, y su abolición por quienes estamos dedicados a esta especialidad siempre ha representado un reto. Una de las herramientas de la terapéutica moderna es el uso de los antiflamatorios no esteroideos (AINES). Desde la antiguedad se han buscado recetas de muy variada índole para su tratamiento, empleándose en algunas civilizaciones el opio o jugo de amapola, el cual era muy usado por los médicos árabes, pero que caería por mucho tiempo en desuso por su alto potencial de dependencia. Es hacia mediados del siglo XIX, tras el seguimiento de muchas investigaciones sobre el poder antipirético de la corteza del sauce que se demuestra la actividad de su principal componente, el ácido salicílico como antiflamatorio y analgésico, llegando en 1853 a prepararse ...

The aim of the study was to evaluate the possible modifications in the arterial pressure, corporal weigh and creatinine cleareance in urine gathered during 24 hours, in healthy young people, under therapy with two non steroidal anti inflammatory drugs (NSAID’s); one of them not selective to Ciclooxigenase (Ibuprofen) and a selective inhibitor of Ciclooxigenase - 2 (Celecoxib), during three days in standardized dose, in comparison with a control group that was administered placebo, in a double blind study. The results indicate that there are not statistically significant differences among the three groups, for the clinical and laboratory evaluated parameters (p <0,05). We conclude that a short term therapy with the used NSAID’s doesn’t produce clinical impact modifications in the arterial pressure, corporal weigh and creatinine cleareance in urine gathered during 24 hours.

Desde la aparición del hombre ha habido una sensación temida, incluso por aquellos más "valientes": la odontalgia o dolor dental, y su abolición por quienes estamos dedicados a esta especialidad siempre ha representado un reto. Una de las herramientas de la terapéutica moderna es el uso de los antiflamatorios no esteroideos (AINES). Desde la antiguedad se han buscado recetas de muy variada índole para su tratamiento, empleándose en algunas civilizaciones el opio o jugo de amapola, el cual era muy usado por los médicos árabes, pero que caería por mucho tiempo en desuso por su alto potencial de dependencia. Es hacia mediados del siglo XIX, tras el seguimiento de muchas investigaciones sobre el poder antipirético de la corteza del sauce que se demuestra la actividad de su principal componente, el ácido salicílico como antiflamatorio y analgésico, llegando en 1853 a prepararse ...

The present investigation incluided: 100 samples, 20 control groups (Universidad Nacional Agraria students), and 80 patients infected with HIVIAIDS; 25 with level If, 35 with level III, and 20patients with level IV. Average proteinic fractions and salivary percentage were taken: Albumin 45.15%, SALIVARY ALBUMIN 15.2%, GAMMAGLOBULIN 75.94% (SIGNIFICANCE LEVEL 1.00%). Problem Sample.- In the problem sample we can see a considerable alteration in the serical electrophorelics proteins. Spit: level II, 22.12% albumin, gammaglobulin 77.64%, level III, albumin 16.35%, gammaglobulin 83.49%. IV 7.71% albumin and 92.37% gammaglobulim. There is a diferrential relationship between normal values of serical gammaglobulim and salivary ones, in HIV/AIDS infected patiens and there is an increase of bucal pathologies.

The present investigation incluided: 100 samples, 20 control groups (Universidad Nacional Agraria students), and 80 patients infected with HIVIAIDS; 25 with level If, 35 with level III, and 20patients with level IV. Average proteinic fractions and salivary percentage were taken: Albumin 45.15%, SALIVARY ALBUMIN 15.2%, GAMMAGLOBULIN 75.94% (SIGNIFICANCE LEVEL 1.00%). Problem Sample.- In the problem sample we can see a considerable alteration in the serical electrophorelics proteins. Spit: level II, 22.12% albumin, gammaglobulin 77.64%, level III, albumin 16.35%, gammaglobulin 83.49%. IV 7.71% albumin and 92.37% gammaglobulim. There is a diferrential relationship between normal values of serical gammaglobulim and salivary ones, in HIV/AIDS infected patiens and there is an increase of bucal pathologies.

The aim of this study was to compare two antibiotic prophylaxis regimens with Clindamycin in patients under semi-retained third lower molar surgery. Third molar extractions were carried out in healthy patients who complied with the inclusion criteria, in the central clinic surgery service of San Marcos University dentistry faculty. After having performed the exodontia control appointments were programmed during 5 days post – extraction where the infection signs were evaluated through the presence or bleeding or exudates on the surgical bed. This registration was carried out for both groups. The obtained data was analyzed using the Mann-Whitney U test (p <0.05). A significant difference was not found in the proportion of cases infected among the groups. However, the results showed a smaller quantity of patients with infection in the group of the intramuscular via (10%) in relation wi...

The aim of this study was to compare two antibiotic prophylaxis regimens with Clindamycin in patients under semi-retained third lower molar surgery. Third molar extractions were carried out in healthy patients who complied with the inclusion criteria, in the central clinic surgery service of San Marcos University dentistry faculty. After having performed the exodontia control appointments were programmed during 5 days post – extraction where the infection signs were evaluated through the presence or bleeding or exudates on the surgical bed. This registration was carried out for both groups. The obtained data was analyzed using the Mann-Whitney U test (p <0.05). A significant difference was not found in the proportion of cases infected among the groups. However, the results showed a smaller quantity of patients with infection in the group of the intramuscular via (10%) in relation wi...