In the present investigation the essential oil of the "lime-lime" (Aloysia aloysioides Loes and Moldenke) was studied, it was collected in the district of Tintay, Apurímac-Peru, the inhabitants of this area, use it for its anti-inflammatory properties in the form of plasters. The objective is to extract and characterize the essential oil of Aloysia aloysioides Loes & Moldenke and evaluate the antibacterial activity. From 674 grams of fresh sample (branches) the essential oil was obtained by steam distillation, then it was characterized by performing a physicochemical analysis, chromatographic by GC-MS, spectroscopic FT-IR and antibacterial analysis. The essential oil was obtained with a yield of 0.38%; β-Caryophyllene (10.88%), limonel (9.9%), p cymene (7.22%), caryophyllene oxide (5.98%), Nerolidol (4.96%) and α-humulene were identified (4.92%) as majority components. In addition...

In this research, a new depside of the lichen Everniopsis trulla has been isolated. The extraction was carried out to 400 g of dry sample and ground with ethanol for 3 repetitions, then, it was fractionated by applying column chromatography with the CHCl3-MeOH system and purified by recrystallization with MeOH-Acetone (1: 1); Finally, white crystals in the form of needles (solid C) with a melting point of 198 ° C were obtained, whose structure was elucidated based on spectroscopic data (UV-Visible, IR, NMR-H1, NMR-C13, mass spectrometry and single crystal X-ray diffraction). According to the Science Finder databases, it is a new depside, called trullarin, and it is observed that molecular packing is influenced by both intramolecular and intermolecular forces. Intermolecular hydrogen bonds of O - H -O type binds neighboring molecules forming dimers.

Seven species of lichens such us Umbilicaria aff. calvescens, Hypotrachyna enderythraea, Punctelia graminicola, Cladonia chlorophaea, Xanthoparmelia farinose, Psiloparmelia distincta (rock and tree substrates; rs and ts), and Usnea durietzii were collected from the province of Arequipa - Peru. Their usnic acid (UA) and fatty acid (FA) amounts in methanol-acetone were determined by High-performance liquid chromatography with diode-array detection (HPLC-DAD) and Gas chromatography-flame ionization detector (GC-FID). The antimicrobial activities of these extracts were evaluated against Staphylococcus aureus ATCC strains (43300, 29213, 25923 and 700699), Escherichia coli strains (O157:H7 and ATCC 10536), Salmonella enterica sv typhimurium ATCC 14028, Candida albicans ATCC 90028 and Candida. tropicalis ATCC 750T. In addition, antioxidant capacity was also studied by Total phenolic content (TP...

Eight new phenylisoxazole isoniazid derivatives, 3-(2'-fluorophenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (1), 3-(2'-methoxyphenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (2), 3-(2'-chlorophenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (3), 3-(3'-clorophenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (4), 3-(4'-bromophenyl)isoxazole-5-carbaldehyde isonicotinylhydrazone (5), 5-(4'-methoxiphenyl)isoxazole-3-carbaldehyde isonicotinylhydrazone (6), 5-(4'-methylphenyl)isoxazole-3-carbaldehyde isonicotinylhydrazone (7), and 5-(4'-clorophenyl)isoxazole-3-carbaldehyde isonicotinylhydrazone (8), have been synthesized and characterized by FT-IR, 1H-NMR, 13C-NMR, and mass spectral data. The 2D NMR (1H-1H NOESY) analysis of 1 and 2 confirmed that these compounds in acetone-d6 are in the trans(E) isomeric form. This evidence is supported by computational calculations which w...