Watery, ethanolic and di-chloromethane extracts made of leafs of Baccharis lanceolata, were assayed by their possible anti-inflamatory activity. Extracts were given oral and topically to rats with plantar edema produced by carragenin or to rats with auricular edema induced by croton oil, respectively. This effect was dosis-dependent and the major effect anti-edema was the dichloromethane extract which produced 68% of inhibition in both patterns.

Se estudiarán botánica y farmacológicamente 4 especies con actividad cicatrizante, con el fin primeramente de clasificarlas en forma adecuada tomando en consideración caracteres morfológicos e histológicos realizando luego las pruebas biológicas correspondientes, cuyos resultados obtenidos se comparan en un cuadro general, caracterizando la especie de mayor efectividad.

Se estudiarán botánica y farmacológicamente 4 especies con actividad cicatrizante, con el fin primeramente de clasificarlas en forma adecuada tomando en consideración caracteres morfológicos e histológicos realizando luego las pruebas biológicas correspondientes, cuyos resultados obtenidos se comparan en un cuadro general, caracterizando la especie de mayor efectividad.

Se estudiarán botánica y farmacológicamente 4 especies con actividad cicatrizante, con el fin primeramente de clasificarlas en forma adecuada tomando en consideración caracteres morfológicos e histológicos realizando luego las pruebas biológicas correspondientes, cuyos resultados obtenidos se comparan en un cuadro general, caracterizando la especie de mayor efectividad.

OBJECTIVE: The gastric protective abilities of dried sap and alkaloid fraction of Croton palanostigma and sucralfate against ethanol-induced necrosis was compared by means of standard experimental rat model. Subchronic toxicity was determined. MATERIAL AND METHODS: A pretreatment with either saline solution, dried sap of C. palanostigma 120 mg/kg, alkaloid fraction of C. palanostigma 20 mg/kg, 35 mg/kg y 50 mg/kg or sucralfate was given to 60 rats. Intragastric administration of 2 mL of 100% ethanol was accomplished one hour later. A gastrectomy was perfomed four hours later followed by macroscopic and histological evaluation of the gastric lesions. Subchronic toxicity was determined with doses of 0,12, 0,40 and 1,20 mL/kg of sap for a 30-day period with biochemical and histopathologic study of the organs. RESULTS: Pretreatment with dried sap and alkaloid fractions of C. palanostigma and...