La interrelación entre el poder y el estado, entre los poderosos y la política, no es un fenómeno de reciente conocimiento, es uno constante, y que en países con órganos estatales débiles se evidencia con mayor fuerza lo que conocemos como conflicto de intereses. Por ello, John Crabtree y Francisco Durand en PERÚ: ÉLITES DEL PODER Y CAPTURA POLÍTICA nos dan un recorrido en el conocimiento de los círculos de poder, pasando por los procesos históricos, la comparación y la actualidad de estos y de nuestro país, viendo, así como, la “captura política”, ha dejado de ser una exclusividad del poder militar para pasar a compartir escenario con las élites económicas.

Eduardo Dargent en una cortísima obra desliza sobre la mesa el argumento de que reformar es más complejo de lo que realmente creemos, pero ¿Qué tan difícil puede ser?

The Instituto Nacional de Enfermedades Neoplásicas (INEN) is a national reference center in Peru where the largest number of pediatric patients with acute lymphoblastic leukemia (ALL) are treated. Methods: Patientes ages 1 to less than 15 years with diagnosis of ALL who received treatment according to the modified 2002 intercontinental Berlin-Frankfurt-Münster (IC-BFM) ALL protocol. Risk stratification was based on age, leukocyte count, extramedullary involvement (CNS, testicular), genetics, and response to initial treatment. Results: From 2014 to 2017, 652 patients were treated, which included 113 with lowrisk ALL, 120 with intermediate-risk ALL, 308 with high-risk ALL, and 103 with very high-risk ALL. The mortality rate during induction was 4.9%, and the remission rate was 90.8%. The abandonment rate was 25.6%. Event-free survival and overall survival at 5 years were 62.9%±4.1% and ...

Survival rates in children with cancer have increased over the years, however the consequences of the oncological treatment received have an impact on different organs and tissues, thus, holocranial radiotherapy and chemotherapy that penetrates the central nervous system can cause consequences. neurocognitive, long-term ocular complications include cataracts, glaucoma, retinopathy and severe dry eye, the use of platinum-based chemotherapy and radiotherapy is associated with hearing loss. The lungs and lung function are vulnerable to injury from oncological treatment and after hematopoietic stem cell transplantation; The use of anthracyclines constitutes the main cause of cardiomyopathy in survivors. At the gastrointestinal level, alkylating agents and anthracyclines can influence the risk of liver and gastrointestinal mucosal damage, and at the kidney level, chemotherapeutic agents such ...

Introduction: Primary central nervous system (CNS) sarcomas are one of the rarest tumors in pediatrics, and an increase in the frequency of these cases has been observed in Peru. This article describes the clinical, demographic characteristics, and survival of pediatric patients with this condition diagnosed at the National Institute of Neoplastic Diseases (INEN). Methods: This is a descriptive observational case series study of a retrospective longitudinal design. Data was collected from 51 patients aged 0-18 years diagnosed with malignant CNS sarcoma between 2009 and 2019 at INEN, and statistical analysis was conducted using the STATA software program. Results: The male-to-female ratio was 1.23. The most common birthplace was Lima. The average age was 7.6 years, and the most frequent location was supratentorial (96.08%; 49/51). There was only one patient with leptomeningeal metastasis....

Background: To provide recommendations based on the best available scientific evidence for the multidisciplinary management of febrile neutropenia. The development included the stages: approval of the creation of the Working Group (WG); CPG search; analysis and synthesis of the evidence that led to establishing the recommendation of the selected CPGs, design of the consensus document, internal review. All phases were carried out through panel meetings using virtual platforms during 03 months. The “GRADE” system was used to establish the strength and direction of the recommendations. The recommendations cover the prevention, diagnosis and treatment of febrile neutropenia in oncohematological patients. Twenty-eight recommendations were developed. The topics approached were: correct evaluation; timely diagnosis, adequate antibiotic treatment, vaccination against influenza and pneumococc...