Survival rates in children with cancer have increased over the years, however the consequences of the oncological treatment received have an impact on different organs and tissues, thus, holocranial radiotherapy and chemotherapy that penetrates the central nervous system can cause consequences. neurocognitive, long-term ocular complications include cataracts, glaucoma, retinopathy and severe dry eye, the use of platinum-based chemotherapy and radiotherapy is associated with hearing loss. The lungs and lung function are vulnerable to injury from oncological treatment and after hematopoietic stem cell transplantation; The use of anthracyclines constitutes the main cause of cardiomyopathy in survivors. At the gastrointestinal level, alkylating agents and anthracyclines can influence the risk of liver and gastrointestinal mucosal damage, and at the kidney level, chemotherapeutic agents such ...