Cervical cancer in Peru - Cancer as a public health risk factors, papilloma virus and cervical, cancer treatment results.

283 cases of carcinoma in situ of the cervix are investigated to establish the value of conization in its diagnosis and treatment. Conization in this series, constitutes the best procedure for diagnosis of invasive lesions and should be preferently used as a guide to the individual treatment. Hysterectomy without previous conization as practised in 27 cases is held as a risk to the patient while the conservative approach with conization alone followed by adequate control renders excellent therapeutic results. However, hysterectomy extended to vagina remains the procedure of choice.

Dysplasia, carcinoma in situ and cervical carcinoma microinvasive are taking great importance in the problem of cervical cancer. Undoubtedly, the increasing frequency with which these diagnoses are made is directly related to the wider dissemination of colpocytology Pap. Obviously, where more centers use this diagnostic method will most cases diagnosed incipient dysplasias and malignant lesions and a significant decrease in advanced cases. The current doctor should know the importance of cytological screening and how to do it, as also the significance of cytologic reports in order to identify patients requiring further research. Finally, he must learn what it is investigating a suspected case and carry it out if you are qualified or refer to another who is trained in this field.

We report 116 cases of benign and malignant tumors of the genital area of children and adolescents up to 17 years, diagnosed in a span of 19 years, from 1952 to 1971 at a single institution. These tumors are rare at this age, they constitute only 0.6%; instead, they are much more common in adult women after age 17, group forming 99.4% of our cases. Of the 116 cases more than a third they corresponded to the group of malignant and almost two-thirds have been benign. 40 cases of malignant tumors of OU casuistry, represent the biggest single resportada so far in series. The most common malignant tumors in childhood and adolescence are ovarian location, which representana more than two-thirds of the total, followed by vaginal location. We emphasize certain gynecological principles that guide the surgeon in the management of benign ovarian tumors in children and adolescents. Our series of gyn...

Although ovarian tumors account for no more than 1% of all neoplasms in the girls under 16 years, they are, however, more common in that period of life genital tumor. Despite their rarity, they should be kept in mind in the differential diagnosis of many abdominal disorders. Because of its rarity, sometimes they undiagnosed and can lead to special problems. Any type of ovarian tumor seen in adult women, has also been found in girls. Approximately 30% of all ovarian tumors in children and adolescents are teratomas or dermoid cyst; moiety includes all kinds of benign and malignant tumors.

This syndrome of varied etiology, is characterized by more or less intense and persistent abdominal pain, accompanied by a set of symptoms and signs that are usually caused by intra-abdominal processes; often, eventually, they will cause first located and then in many cases, acute generalized peritonitis. This peritoneal box, if left to evolve freely, take the patient to the toxic and hypovolemic shock, progressive and irreversible progress, and ultimately death.

Casuistry of gynecologic malignancies at the Institute of Neoplastic Diseases

El director del Centro Detector del Cáncer informa la labor desarrollada por esta institución, única de su índole en Sudamérica. Más de 2,000 mujeres, aparentemente sanas, fueron examinadas en este Centro; su estudio llevó a la ejecución de un informe sobre los resultados obtenidos, que es objeto de este trabajo. El Centro Detector del Cáncer de Lima fue establecido el 19 de junio de 1953, bajo los auspicios de la Liga Peruana de Lucha contra el Cáncer y la gran cooperación del Instituto Nacional de Enfermedades Neoplásicas, que le brinda todas las facilidades para una labor eficaz. Las mujeres fueron examinadas entre el 8 de junio de 1953 y el 15 de febrero de 1954. Se estudiaron todos los casos minuciosamente, estudio ejecutado por los diversos equipos que constituyen el personal médico del Centro Detector, personal exprofesamente contratado en el Instituto Nacional de Enf...

Casuistry of gynecologic malignancies at the Institute of Neoplastic Diseases

We report 116 cases of benign and malignant tumors of the genital area of children and adolescents up to 17 years, diagnosed in a span of 19 years, from 1952 to 1971 at a single institution. These tumors are rare at this age, they constitute only 0.6%; instead, they are much more common in adult women after age 17, group forming 99.4% of our cases. Of the 116 cases more than a third they corresponded to the group of malignant and almost two-thirds have been benign. 40 cases of malignant tumors of OU casuistry, represent the biggest single resportada so far in series. The most common malignant tumors in childhood and adolescence are ovarian location, which representana more than two-thirds of the total, followed by vaginal location. We emphasize certain gynecological principles that guide the surgeon in the management of benign ovarian tumors in children and adolescents. Our series of gyn...

283 cases of carcinoma in situ of the cervix are investigated to establish the value of conization in its diagnosis and treatment. Conization in this series, constitutes the best procedure for diagnosis of invasive lesions and should be preferently used as a guide to the individual treatment. Hysterectomy without previous conization as practised in 27 cases is held as a risk to the patient while the conservative approach with conization alone followed by adequate control renders excellent therapeutic results. However, hysterectomy extended to vagina remains the procedure of choice.

Using in situ hybridization, human papaillomavirus type 16 was identified in both primary and recurrent cervical carcinoma following radiation therapy.

Basal cell carcinoma of the vulva is a very rare lesion, and occupies the fourth place in the total of malignant tumors of the vulva attended at the Instituto Nacional de Enfermedades Neoplasicas of Lima, with an incidence of 2,7 per cent. The simple vulvectomy is the most adequate from of therapy when the basal cell carcinoma is present by itself, i.e. pure. The radical vulvectomy and bilateral regional node dissection must be practiced in all cases of basal squamous cells lesions.

Basal cell carcinoma of the vulva is a very rare lesion, and occupies the fourth place in the total of malignant tumors of the vulva attended at the Instituto Nacional de Enfermedades Neoplasicas of Lima, with an incidence of 2,7 per cent. The simple vulvectomy is the most adequate from of therapy when the basal cell carcinoma is present by itself, i.e. pure. The radical vulvectomy and bilateral regional node dissection must be practiced in all cases of basal squamous cells lesions.

The authors have studied 68 cases of carcinoma of the cervical stump treated at the INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS, Lima, between 1952 - 1967. By applying the criteria of two years free interval, 49 of these cases were "authentic" and 19 were of the coincident type. These 68 cases represented 0.7 % of the 9.197 cases of carcinoma of the cervix treated in the 15 years period. The overall survival rate for the surgical treated group was 50 % and 47 % for those who received roentgen therapy; however, after analysis of the clinical stages of the cases in both groups the authors suport radiation therapy as the more adequate procedure.

The authors have studied 68 cases of carcinoma of the cervical stump treated at the INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS, Lima, between 1952 - 1967. By applying the criteria of two years free interval, 49 of these cases were "authentic" and 19 were of the coincident type. These 68 cases represented 0.7 % of the 9.197 cases of carcinoma of the cervix treated in the 15 years period. The overall survival rate for the surgical treated group was 50 % and 47 % for those who received roentgen therapy; however, after analysis of the clinical stages of the cases in both groups the authors suport radiation therapy as the more adequate procedure.

The Peruvian Society of Obstetrics and Gynecology through its standing committee proposes training leaders in this project in order to deepen and broaden knowledge and skills in the specialty of ginecoobtetricia especially in the fields of perinatology, obstetrics and gynecology Human Reproduction and Oncology gynecological. It is proposed to develop an annual program that offers the opportunity to young doctors who have completed their residentado of obstetrics and gynecology or ginecoobstetras doctors who are practicing in a hospital MOH and IPSS, who through a selection process to obtain grants to develop knowledge , skills, and leadership responsibilities in the fields of human reproduction, perinatology and oncology, for which they must be assigned to a teaching hospital prequalified for a year.

Between 1962 and 1980, the Departments of Gynecology and Medical Oncology INEN have handled 170 cases of trophoblastic disease. All patients had clinical and / or radiographic evidence and hormonal disease activity; histopathologic evidence was obtained when the disease was accessible to biopsy. Half of the patients are in the third decade of life, and a quarter in the fourth decade; 8 percent were under 20 years old. Only 27 percent of cases were under three months of sick time; in 21 percent of cases the disease duration was more than one year. 64.7% of cases had a history of mole, and 20 percent of abortion; in 10% of cases of history was normal delivery. Only 110 patients (64.75%) showed evidence of pelvic disease admission; 35% of 110 cases found evidence of disease in the pelvis. 55% of cases presented lung metastases, and 20% vulvovaginal metastasis; intestinal metastasis, liver o...

The authors have studied 9 cases of primary carcinoma of the Fallopian tube; this means an incidence of 0.09 % in a total of 9266 malignant tumors of the genital tract observed at the Instituto Nacional de Enfermedades Neoplásicas, Lima Perú, between 1952 and 1966. The patients had an average age of 50 years, range 33-70; the treatment was surgical and radiation, and the overall survival rate was 22 %.

Between 1962 and 1980, the Departments of Gynecology and Medical Oncology INEN have handled 170 cases of trophoblastic disease. All patients had clinical and / or radiographic evidence and hormonal disease activity; histopathologic evidence was obtained when the disease was accessible to biopsy. Half of the patients are in the third decade of life, and a quarter in the fourth decade; 8 percent were under 20 years old. Only 27 percent of cases were under three months of sick time; in 21 percent of cases the disease duration was more than one year. 64.7% of cases had a history of mole, and 20 percent of abortion; in 10% of cases of history was normal delivery. Only 110 patients (64.75%) showed evidence of pelvic disease admission; 35% of 110 cases found evidence of disease in the pelvis. 55% of cases presented lung metastases, and 20% vulvovaginal metastasis; intestinal metastasis, liver o...