A nivel mundial, nuestro tiempo vive contradicciones sustanciales. Mientras hay profundos avances en el camino hacia la mayor participación y la expansión democrática, también se están produciendo regresiones hacia problemas que se creían totalmente superados como es el caso que en algunos estratos aún se siga considerando al género como un marcador de diferencia.

Introducción: La progresión y la falta de opciones terapéuticas conlleva a un gran aumento de la morbi-mortalidad en la esclerodermia sistémica cutánea difusa. Caso Clínico: Se presentan tres pacientes con diagnóstico de Esclerodermia sistémica de rápida progresión sin compromiso cardiopulmonar o renal severo con múltiples líneas de tratamiento incluyendo altas dosis de ciclofosfamida, sometidas a trasplante autólogo (2015-2020) con acondicionamiento a base de Ciclofosfamida y Globulina Antitimocitica, como opción terapéutica. Durante el procedimiento no se observaron complicaciones infecciosas severas con un prendimiento medular en el día 10 y una recaída promedio de 9.6 meses. Conclusiones: Ante el buen perfil de toxicidad y la buena tolerancia al procedimiento se debe considerar al Trasplante Autólogo como una opción de tratamiento en pacientes sin altas dosis acumu...

Background: The progression and lack of therapeutic options leads to a large increase in morbidity and mortality in diffuse cutaneous systemic scleroderma. Clinical Case: Three patients with a diagnosis of rapidly progressing systemic scleroderma without severe cardiopulmonary or renal involvement with multiple lines of treatment including high doses of cyclophosphamide, submitted to autologous transplant (2015-2020) with conditioning based on Cyclophosphamide and Antithymocyte Globulin are presented as a therapeutic option. During the procedure, no various infectious infections were observed with a medullary seizure on day 10 and an average relapse of 9.6 months. Conclusions: Due to the good toxicity profile and good tolerance to the procedure, Autologous Transplantation should be considered as a treatment option in patients without high accumulated doses of cyclophosphamide or in early...

Background: The progression and lack of therapeutic options leads to a large increase in morbidity and mortality in diffuse cutaneous systemic scleroderma. Clinical Case: Three patients with a diagnosis of rapidly progressing systemic scleroderma without severe cardiopulmonary or renal involvement with multiple lines of treatment including high doses of cyclophosphamide, submitted to autologous transplant (2015-2020) with conditioning based on Cyclophosphamide and Antithymocyte Globulin are presented as a therapeutic option. During the procedure, no various infectious infections were observed with a medullary seizure on day 10 and an average relapse of 9.6 months. Conclusions: Due to the good toxicity profile and good tolerance to the procedure, Autologous Transplantation should be considered as a treatment option in patients without high accumulated doses of cyclophosphamide or in early...

This research presents the results that we have extracted from the impact of citizen participation and the organizational commitment of teachers at an art university. Our objective is to determine the relationship that exists between citizen participation and the organizational commitment of ENSABAP teachers. Four specific objectives were established to analyze the relationship with institutional decision-making. Methodology: Our work methodology starts from a theoretical approach in which it is characterized by being descriptive, correlational, basic, non-experimental, with a quantitative and cross-sectional methodological approach. The Participation Behavior Questionnaire by Vergara and Hevia (2012) and the Organizational Commitment Questionnaire by Meyer et al. (1993) were used. These questionnaires were answered by 62% of the teachers who made up a non-probabilistic sample. Results: ...

Man by nature is a homo pensantis. This means that he has the capacity to analyze, synthesize, deduce, etc. However, we must question how educational institutions strengthen critical thinking (CP). Therefore, the purpose of this study was to analyze its level in academic tasks assigned in the classroom context based on active methodologies as an integral element of a quality and sustainable education. The methodology was based on a documentary review with a qualitative and bibliometric approach. The corpus consisted of thirty-one articles extracted from the Scopus database. Likewise, the PRISMA technique was used for the exclusion and inclusion of the documents consulted. The writings are from the years 2020 to 2023. The results showed that CP is a limitation for the student, since its exercise demands the use of complex cognitive skills such as analysis, interpretation, inference, evalu...