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https://purl.org/pe-repo/ocde/ford#5.02.04
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https://purl.org/pe-repo/ocde/ford#6.04.08
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ODS 3: Salud y bienestar. Garantizar una vida sana y promover el bienestar de todos a todas las edades
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https://purl.org/pe-repo/ocde/ford#3.03.03
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https://purl.org/pe-repo/ocde/ford#5.01.00
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https://purl.org/pe-repo/ocde/ford#2.01.00
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https://purl.org/pe-repo/ocde/ford#3.02.10
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structure function » estructura funcion (Expander búsqueda), structure detection (Expander búsqueda), structure factor (Expander búsqueda)
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1
tesis doctoral
Publicado 2024
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Mycobacterium tuberculosis (Mtb) sigue siendo uno de los patógenos más mortales a nivel mundial, a pesar de ser una enfermedad prevenible. La tuberculosis (TB) se trata con una combinación de cuatro medicamentos antituberculosos de primera línea: rifampicina (RIF), isoniacida, pirazinamida y etambutol, para cepas sensibles a los medicamentos. Entre estos, la RIF es uno de los agentes más potentes para controlar la enfermedad. Sin embargo, la resistencia a la RIF conlleva la aparición de casos de TB resistente a la RIF (RR-TB) o multidrogo resistente (MDR-TB). El mecanismo principal de resistencia implica mutaciones en el gen rpoB, que es responsable de aproximadamente el 95% de los casos. No obstante, todavía se están identificando otros mecanismos moleculares y condiciones que podrían contribuir a la propagación de las poblaciones RR-TB y MDR-TB. Esta investigación doctoral s...
2
artículo
Publicado 2025
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El estudio evaluó la estructura poblacional y los parámetros productivos y reproductivos de 1149 bovinos Brown Swiss criados en 101 rebaños en tres sectores (K´uchuhuasi, Cullahuata y Alccavictoria) del distrito de Velille, Cusco, situados en altitudes que varían entre 3650 y 3900 msnm. Se realizaron encuestas y se analizaron registros existentes de estas poblaciones correspondientes a los años 2021, 2022 y 2023. Para el análisis de los datos se realizó un análisis de varianza y se empleó la función LSMENANS de la librería emmeans usando el lenguaje de programación R v. 4.0 y RStudio. No se encontraron diferencias significativas (p>0.05) entre sectores en la mayoría de las categorías de la estructura poblacional. El porcentaje de vacas en producción estuvo entre 33.98 ± 11.53% y 36.6 ± 12.88%. Los parámetros productivos y reproductivos evaluados no difirieron entre ...
3
artículo
Publicado 2024
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Objective. To determine the influence of family functionality on the nutritional status of children aged 1 to 5 years in a rural area of Huánuco (Peru) in 2023. Methods. The study was observational, cross-sectional, prospective, and analytical, with an explanatory level. The sample consisted of the census population, made up of 106 heads of families with their youngest child, aged 1 to 5 years. The Family APGAR Scale was used to measure family functionality, and the anthropometric chart was used to measure nutritional status. Fisher's test was applied for hypothesis testing. Results. The majority of participants perceived a family functionality of 86.8% (92), followed by those representing family dysfunctionality of 13.2% (14). It was also observed that most had an appropriate height for their age 47.2% (50), normal weight for age values 66.0% (70), and normal weight for height values i...
4
artículo
Publicado 2020
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Adolescence is a critical period where social skills play an important role in the personal performance of each individual, for which the family plays a fundamental role in the development and consolidation of these social skills. The article aims to identify the relationship between social skills in adolescents and family functionality. Quantitative research method, descriptive - correlational type; With a population of 726 and a sample of 251 students from first to fifth year of high school, it was carried out using stratified random probability sampling. The instrument that was used is the structured test of social skills of the Ministry of Health and the family APGAR that evaluates five basic functions Adaptation, Participation, Gradient of personal resource, Affection, and Resources. The results indicate that there is a positive correlation between social skills and family functiona...
5
artículo
Publicado 2020
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The relevance of the problem under study is due to the need to organize preventive work to counter extremist activities and terrorist threats in the country, implement measures to form the population's anti-terrorist consciousness, improve measures of an informational and propaganda nature and protect the information space of the State from the ideology of extremism and terrorism. The purpose is to find new solutions and to develop a structural and functional model aimed at preventing and countering the spread of religious extremist and terrorist activities on the territory of the State by the services and divisions of the Federal Penitentiary System of Russia (FPSR) and the Ministry of Internal Affairs of Russia (MIA of Russia) and other law enforcement agencies, state and public organizations, as well as a closer interaction of these organizations in the fight against destructive ass...
6
artículo
Publicado 2020
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In the present investigation we present a polysiloxane composite functionalized with silver nanoparticles (NPs-Ag). NPs-Ag was synthesized, by reduction of a silver nitrate solution (AgNO3) with sodium borohydride (NaBH4), the NPs-Ag were characterized by the UVvisible spectrophotometric method, finding that between 400 - 410 nm the typical peak of NPs-Ag by surface plasmon resonance. In the Dynamic Light Scattering (DLS) analysis of the NPs-Ag, a polydisperse distribution was found with two populations of 59.78 nm in 70% and 4.33 nm in 30%. Subsequently, the polysiloxane gel was synthesized by hydrolyzing chlorosilane, using diethyl ether as the solvent, the obtained polysiloxane was characterized by infrared Fourier transform spectrophotometry (FTIR). In the spectrum peaks are observed in the region of 1258.88 cm-1 corresponding to methyl, between 1000 - 1100 cm-1 a peak corresponding ...
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artículo
Background: Insomnia can harm daily functioning and is strongly associated with depression and anxiety symptoms, especially in women. El Salvador has no scales with adequate psychometric properties for their measurement. In this context, the Athens Insomnia Scale (AIS) is a viable option to measure this symptomatology, given its short length of time, solid theoretical foundation, and relevance in other countries. Objective: To analyze the psychometric properties of AIS in the Salvadoran population, in its complete (AIS-8) and abbreviated (AIS-5) versions. Method: The study consisted of 1479 Salvadoran adults from the 14 departments of the country (mean age = 33.3 years, SD = 11.7) who were screened through a non-probability sampling design. Evidence of reliability, validity based on internal structure, and convergent validity were examined. Results: Both scales showed adequate internal c...
8
artículo
Publicado 2023
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The objective was to determine the psychometric properties of the F-COPES in the Colombian population. Cross-sectional study, with 1373 people, aged between 18 and 84 years. Data were analyzed in Jasp, exploratory factor analyzes were performed using the weighted least squares estimation method and a promax-type oblique rotation. Confirmatory factor analyzes with diagonalized weighted least squares estimators and robust analysis methods. Internal consistency analysis using Cronbach’s Alpha indices, McDonald’s Omega, and the highest lower limit index. A structure of five factors was found, four original ones: finding social support, cognitive restructuring, finding spiritual support and passive evaluation, and a new one: neighbor support. The scale evaluates family functioning in crisis situations in the Colombian context.
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artículo
Publicado 2022
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Objective: The purpose of this work was to expose the qualities and capacities that adapted, Paralympic and inclusive sport possesses, its effect of abolition on a series of discriminatory stereotypes against functional diversity, limitations that are still maintained in certain societies. Various realities are analyzed where inclusive government policies have been developed based on physical-sports practices in populations with disabilities, detailing the specific case of Ecuador. Method: This research was based on a documentary-bibliographical exploration, using the following databases: Psycinfo, Medline, Ebsco, Scielo, Psicodoc, PsycArticles, and the main repositories of postgraduate institutions. Within this selection procedure, only bibliographic material published within a range of the last five years was considered. Under these criteria, 75 papers were obtained, of which 33 were s...
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artículo
Publicado 2018
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Camu camu is a typical Amazon native fruit shrub that possesses a diploid genome, moderate genetic diversity, and population structure. The fruits accumulate several essential nutrients and synthesize L-ascorbic acid (vitamin C) in great quantities and an array of diverse secondary metabolites with corroborated in vitro and in vivo health-promoting activities. These beneficial effects include antioxidative and antiinflammatory activities, antiobesity, hypolipidemic, antihypertensive and antidiabetic effects, DNA damage and cancer protection effects, and other bioactivities. Many health-promoting phytochemicals are biosynthesized in several metabolic pathways of camu camu. Their reconstruction from the fruit transcriptome database was accomplished by our research group. These include basic metabolic pathways such as glycolysis and pentose phosphate pathway, vitamin C biosynthesis pathways...
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artículo
Publicado 2020
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Western South America was one of the worldwide cradles of civilization. The well-known Inca Empire was the tip of the iceberg of an evolutionary process that started 11,000 to 14,000 years ago. Genetic data from 18 Peruvian populations reveal the following: 1) The between-population homogenization of the central southern Andes and its differentiation with respect to Amazonian populations of similar latitudes do not extend northward. Instead, longitudinal gene flow between the northern coast of Peru, Andes, and Amazonia accompanied cultural and socioeconomic interactions revealed by archeology. This pattern recapitulates the environmental and cultural differentiation between the fertile north, where altitudes are lower, and the arid south, where the Andes are higher, acting as a genetic barrier between the sharply different environments of the Andes and Amazonia. 2) The genetic homogeniza...
12
artículo
Publicado 2024
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The impact of the global COVID-19 pandemic on health systems has created a chaotic scenario, severely hindering the ability to meet health needs and negatively affecting the provision of health services to the population. This prolonged health crisis has exposed the collapse of health systems and their lack of institutional capacity to effectively address health emergencies. This situation is largely attributable to the segmentation and fragmentation rooted in the regional structure of these systems. Meanwhile, limited progress has been made in evaluating their performance. One of the primary objectives of health systems is universal health coverage. Nevertheless, achieving this goal requires the implementation of strategies aimed at strengthening these systems through the evaluation of their performance and the promotion of international health security. In this context, essential publi...
13
artículo
Publicado 2024
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The systematic review was carried out using the PRISMA methodology and focused on the search for scientific articles in which the effects of omega-3 or creatine supplementation in adults over 60 years of age and its effect on cognitive function had been investigated. The search criteria were supplementation, omega 3, creatine, older adults, memory, function and cognitive impairment. The exclusion criteria were athletes and people under 60 years of age. Articles from PubMed, ScienceDirect and SciELO were included. 223 articles were found investigating the effect of omega-3 supplementation and 25 articles on creatine supplementation, of which 29 and 3 were selected that met the inclusion and exclusion criteria respectively for each group. Concluding that adequate consumption of sources of omega 3 and creatine has a preventive benefit against memory conditions and cognitive deterioration re...
14
artículo
Publicado 2024
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The systematic review was carried out using the PRISMA methodology and focused on the search for scientific articles in which the effects of omega-3 or creatine supplementation in adults over 60 years of age and its effect on cognitive function had been investigated. The search criteria were supplementation, omega 3, creatine, older adults, memory, function and cognitive impairment. The exclusion criteria were athletes and people under 60 years of age. Articles from PubMed, ScienceDirect and SciELO were included. 223 articles were found investigating the effect of omega-3 supplementation and 25 articles on creatine supplementation, of which 29 and 3 were selected that met the inclusion and exclusion criteria respectively for each group. Concluding that adequate consumption of sources of omega 3 and creatine has a preventive benefit against memory conditions and cognitive deterioration re...
15
artículo
Publicado 2024
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Background: Depression and anxiety are two of the most prevalent and disabling mental disorders worldwide, both in the general population and in outpatient clinical settings. Objective: This study aimed to analyze the psychometric properties of the Patient Health Questionnaire-4 (PHQ-4) based on network analysis metrics. Methods: A total of 911 Paraguayans (23.71% women and 76.29% men; mean age 31.25 years, SD = 10.63), selected by non-probabilistic convenience sampling, participated in the study. Network analysis was used to evaluate the internal structure, reliability, and measurement invariance between men and women. Results: The results revealed that the PHQ-4 is a unidimensional measure through Exploratory Graph Analysis (EGA). Reliability, through structural consistency, identified that 100% of the time, only a single dimension was obtained, and all items remained stable, as they w...
16
artículo
Publicado 2024
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Background: Depression and anxiety are two of the most prevalent and disabling mental disorders worldwide, both in the general population and in outpatient clinical settings. Objective: This study aimed to analyze the psychometric properties of the Patient Health Questionnaire-4 (PHQ-4) based on network analysis metrics. Methods: A total of 911 Paraguayans (23.71% women and 76.29% men; mean age 31.25 years, SD = 10.63), selected by non-probabilistic convenience sampling, participated in the study. Network analysis was used to evaluate the internal structure, reliability, and measurement invariance between men and women. Results: The results revealed that the PHQ-4 is a unidimensional measure through Exploratory Graph Analysis (EGA). Reliability, through structural consistency, identified that 100% of the time, only a single dimension was obtained, and all items remained stable, as they w...
17
artículo
Publicado 2022
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Nomophobia understood as fear of not being able to contact or make use of a smartphone, irrational fear of losing it, running out of batteries or being without an internet signal, which generates high rates of anxiety. The consumer behaviors of this virtual society lead to the postponement of personal, academic and work objectives because more time is spent performing online activities, which turn out to be more attractive and less complex. The main objective of this research has been to determine the factorial structure, validity and reliability of the Nomophobia Scale (NMPQ). 300 students participated in a State University of Metropolitan Lima. The confirmatory factor analysis corroborated a structure of four factors, showing adequate adjustment indicators composed of CFI= .997, TLI= 0.997 and RMSEA= 0.084. confirming a second-order model, plus a first-order model. Cronbach's a...
18
informe técnico
Publicado 2015
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Considerando a la familia, como una unidad o sistema de interacción humana y por ende de interacción social según el tipo de estructura familiar, con reglas interactivas que muy a menudo son implícitas, en donde suelen hacerse visibles cuando comienzan a tomarse funcionales o disfuncionales en porcentajes considerables a nivel regional, nacional y mundial. El objetivo general fue explicar la influencia de la estructura familiar sobre el nivel de rendimiento académico en estudiantes de la Escuela Profesional de Enfermería Universidad Nacional del Callao 2014. Respecto a los materiales y métodos se llevó a cabo un estudio de tipo descriptivo, diseño no experimental de corte transversal prospectivo, la población estudiada fue de 612 estudiantes matriculados del 1 al X ciclo en la Escuela Profesional de Enfermería Universidad Naciop.al del Callao, la muestra fue probabilística es...
19
artículo
Publicado 2014
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Mannose-binding lectin (MBL) is one of the five recognition molecules in the lectin complement pathway. Common variant alleles in the promoter and structural regions of the human MBL gene (MBL2) influence the stability and serum concentration of the protein. Epidemiological studies have shown that MBL2 variant alleles are associated with susceptibility to and the course of different types of infectious and inflammatory conditions. However, it has been suggested that these alleles are maintained in different populations due to selected advantages for carriers. We investigated the MBL2 allelic variation in indigenous individuals from 12 different West Central South America localities spanning from the desert coast, high altitude Andean plates and the Amazon tropical forest within the territories of Peru (n = 249) (Departments of Loreto, Ucayali, Lambayeque, Junin, Ayacucho, Huancayo and Pu...
20
artículo
Publicado 2022
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La morfometría es una herramienta para cuantificar y analizar la variación morfológica en el tamaño y forma de los animales. El objetivo del estudio fue contribuir a la caracterización morfométrica del cerdo criollo araucano para conocer algunas de sus características funcionales y etnológicas. Se estudiaron 58 cerdos (27 hembras y 31 machos), con edades entre 4 a 48 meses, localizados en tres veredas de Arauca, oriente de Colombia. Se obtuvieron 11 medidas corporales individuales y se construyeron tres índices. Se aplicó estadística descriptiva y un análisis univariado para medir el efecto ambiental sobre las medidas corporales e índices, usando la edad como covariable. Los cerdos presentaron una variabilidad media en las medidas corporales asociada con una mediana armonía. Los cerdos se consideran dolicocéfalos, mesolíneos y no aptitud cárnica. Las hembras tendían a s...
